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The map label for this gene is lspA [H]

Identifier: 94311818

GI number: 94311818

Start: 3141487

End: 3142023

Strand: Direct

Name: lspA [H]

Synonym: Rmet_2886

Alternate gene names: 94311818

Gene position: 3141487-3142023 (Clockwise)

Preceding gene: 94311817

Following gene: 94311819

Centisome position: 79.97

GC content: 62.38

Gene sequence:

>537_bases
ATGGCATCGTCCACTCGTTCGACGCGTTCGACGCCGGCCCGCGGCAAGAGCAAGGGCGCCAGCGGCAACGTCACGCCGTG
GCTGTGGATGGCCTTTGCCCTGCTGGTGGTGATGATCGACCAGTTCTTCAAGGTGGTGATCACGCGCTCGTTCCAGTACG
GCGAGTCGCGCCCGATCACCAGCTTCTTCAATCTGGTGCTGGTCTATAACAAGGGTGCCGCGTTCAGCTTCCTGGCAGAT
GCGGGCGGCTGGCAGCGCTGGTTCTTCACGCTGCTGGGCGTGGTGGTCGGCGCGTTCATCATCTGGCTGCTCTATCGCCA
TACCGGACAGAAGCTGTTTTGCCTGGCGGTATCACTGATTCTCGGTGGCGCCGTGGGCAATGTGGTCGACCGGATCATCC
ACGGCCACGTGATCGACTTCCTGGACTTCCATCTGCGTAACACGCATTTCCCGGCATTCAACGTGGCGGACTGCGCGATC
ACGCTCGGGGCGATCCTGCTGATCGTCGACGAGCTGCGGCGCGTGCGACGTCACTGA

Upstream 100 bases:

>100_bases
ACTACCGCGCCGACGTGGGCCACAACCCCGAGCATCCGACGATCTGCGGCCGCTGCGACAGCAACCTGTTCGGCGCCGGT
GAACACAGGAGCCACGCCTG

Downstream 100 bases:

>100_bases
CGCCTGTCATACGCCCCTCTCCCACAAGCGGGAGAGGGCGCCAGCCAACCATCCCTTCCAGCGCGTCGCCTCTCCCAGCG
GTATCATGCGCAGACTCCCG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MASSTRSTRSTPARGKSKGASGNVTPWLWMAFALLVVMIDQFFKVVITRSFQYGESRPITSFFNLVLVYNKGAAFSFLAD
AGGWQRWFFTLLGVVVGAFIIWLLYRHTGQKLFCLAVSLILGGAVGNVVDRIIHGHVIDFLDFHLRNTHFPAFNVADCAI
TLGAILLIVDELRRVRRH

Sequences:

>Translated_178_residues
MASSTRSTRSTPARGKSKGASGNVTPWLWMAFALLVVMIDQFFKVVITRSFQYGESRPITSFFNLVLVYNKGAAFSFLAD
AGGWQRWFFTLLGVVVGAFIIWLLYRHTGQKLFCLAVSLILGGAVGNVVDRIIHGHVIDFLDFHLRNTHFPAFNVADCAI
TLGAILLIVDELRRVRRH
>Mature_177_residues
ASSTRSTRSTPARGKSKGASGNVTPWLWMAFALLVVMIDQFFKVVITRSFQYGESRPITSFFNLVLVYNKGAAFSFLADA
GGWQRWFFTLLGVVVGAFIIWLLYRHTGQKLFCLAVSLILGGAVGNVVDRIIHGHVIDFLDFHLRNTHFPAFNVADCAIT
LGAILLIVDELRRVRRH

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=145, Percent_Identity=43.448275862069, Blast_Score=123, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19905; Mature: 19773

Theoretical pI: Translated: 10.97; Mature: 10.97

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSTRSTRSTPARGKSKGASGNVTPWLWMAFALLVVMIDQFFKVVITRSFQYGESRPIT
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
SFFNLVLVYNKGAAFSFLADAGGWQRWFFTLLGVVVGAFIIWLLYRHTGQKLFCLAVSLI
HHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGGAVGNVVDRIIHGHVIDFLDFHLRNTHFPAFNVADCAITLGAILLIVDELRRVRRH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASSTRSTRSTPARGKSKGASGNVTPWLWMAFALLVVMIDQFFKVVITRSFQYGESRPIT
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
SFFNLVLVYNKGAAFSFLADAGGWQRWFFTLLGVVVGAFIIWLLYRHTGQKLFCLAVSLI
HHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGGAVGNVVDRIIHGHVIDFLDFHLRNTHFPAFNVADCAITLGAILLIVDELRRVRRH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA