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The map label for this gene is siaT [H]

Identifier: 94311685

GI number: 94311685

Start: 2992394

End: 2994118

Strand: Direct

Name: siaT [H]

Synonym: Rmet_2753

Alternate gene names: 94311685

Gene position: 2992394-2994118 (Clockwise)

Preceding gene: 94311684

Following gene: 335055629

Centisome position: 76.18

GC content: 64.75

Gene sequence:

>1725_bases
ATGATTCCATTGGAATATATGCCGCCGCTCATGTTCGGCGGCTTGGTGGTATTTATGCTGATCGGGTTCCCGGTCGCATT
CTCGCTGTCGGCCGTGGGTCTGGCCTTCGGCTTCCTGGCCATCGAATGGGGCTACTTCCCCGTGCAGTTCCTGCAGGCCG
TGCCAAGCCGCGTGTTCGGCAGCGTGCTGTCCAACGAACTGCTGCTGGCGATTCCGTTCTTCACCTTCATGGGCGCGATC
CTGGAGAAATGCGGACTCGCGGAGGACATGCTCGACTCGATGGGCCAGTTGTTCGGCCCGGTTCGTGGCGGCCTGGGCTA
CTCGGTCATCATCGTCGGCTTCATCCTGGGCGCGATCACCGGCACGGTGGCGGCGCAGGTGATCGCCATGGCCATGATCT
CGCTGCCCGTGATGATGCGCTACCGCTACAACATGAAGTACGCCACGGGCGTGCTGGCCGCATCGGGCACGATCACCCAG
CTGGTGCCGCCGTCGCTGGTGCTGGTGGTGCTGGCCGACCAGTTGAAGACCCCGGCCGGTAGCGCCGACGTCGGCAGCAT
GTACCTGGGCGCGTGGGGCCCGTCGGTGATCCAGATCGCGCTGTTCGCGCTCTACACCTTCGTGCTGACCCGCATCAAAC
CAGACTGGCTGCCGCCGGTGCCGGAAGAAGCGCGCACGCTGCGCGGCTGGGCGCTGTGGCGTACCTGCCTGCGCGGCATC
ATCCCCTGCGCCGTGCTGATCTTCCTGGTGCTCGGCACGATCATGCTCGGCATCGCCACGCCGACCGAGTCCGGAGCGAT
GGGCGCGGTTGGCGCGCTGGTGCTGGCCGTGATCCGCGACAAGGGCTTCAACAAGATCGACCGCAACATCTATCGGCTGG
GCCTGTTGGCAACGCTGGTGGCCGCTGCGGTGGGCGTCTTCGCATTCGGCTCGCATGCGTTCCGCATCCCGCTGGCGATT
GCCTACCTTGTGGTGTTGTGGCTCCTGATCCGCGCCGGCCAGCTTACCGACCTGCGGCTGCTGATCGTGGATGCCTACCA
ATCCACCGCGCGCATCACCGCCATGGTCGTGTTCATCCTGATTGGATCCACCTGCTTCTCGGTGGTGTTCCAGGGCGTGG
ACGGCGGCGCATGGGTGGAACACCTGTTCACCTCGCTACCGGGCGGCTGGATCGGCTTCCTGATCGTGGTGAACCTGTTC
ATCTTCTTCCTGGCGTTCTTCCTCGACTTCTTCGAGATCGCGTTCATCGTCGTGCCGATGCTGGCGCCGGTTGCGGTCAA
GGTGCTGGCCCCGGTGGTAGCCGATTCGATGGGCGGCAACCCCGAAGCCGCCGCCACGGCCGCGCTGGTCTGGTTCGGCG
TGATGCTGTGCGTGAACATGCAGACGTCGTTCATGCACCCGCCGTTCGGCTTCGCGCTGTTCTACCTGCGCGGCATCGCC
CCGAAGGAAGTCAAGAGCTCGGACATCTACTGGGGTGCCCTGCCGTGGGTGGGCCTGCAGCTCGTCATGGTGCTGCTGGT
GATGTTCTGGCCGGGCATGGTGACTGGCCTGCTCGACAAGGGATCGCTCAAACACAGTAATTCCGCCGAGGTCAGTATCC
CGCTTGGCGGACAGGACGATGGCAAGCCCGGGGGGGCGTCCTCGCCCGGCACGCTGGAGTTGCCGAGCGGCGGCGACTCG
AGTGAACCGGTGGCGCCTTCGTTCCAGTTCGAGAAAAGCAAGTAG

Upstream 100 bases:

>100_bases
CCCTGCTCACGCTGCAGGGGATTTCCGAACTGATCAAGCGCTTCGCCGCCCTGCAGGGCCTGCTGCGCATCGAATCGAAA
TACGAAAGGCCGGTGCAATA

Downstream 100 bases:

>100_bases
CTGGATTGAAGTGGGGTTGGAGGGTGATGCGCTGACCCTCTCCCTCTCCCCACAGATCACGCAAGACACAAAAAACCCCC
GGCCTCACGGCACGGGGGTT

Product: TRAP-type transporter, large permease

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MIPLEYMPPLMFGGLVVFMLIGFPVAFSLSAVGLAFGFLAIEWGYFPVQFLQAVPSRVFGSVLSNELLLAIPFFTFMGAI
LEKCGLAEDMLDSMGQLFGPVRGGLGYSVIIVGFILGAITGTVAAQVIAMAMISLPVMMRYRYNMKYATGVLAASGTITQ
LVPPSLVLVVLADQLKTPAGSADVGSMYLGAWGPSVIQIALFALYTFVLTRIKPDWLPPVPEEARTLRGWALWRTCLRGI
IPCAVLIFLVLGTIMLGIATPTESGAMGAVGALVLAVIRDKGFNKIDRNIYRLGLLATLVAAAVGVFAFGSHAFRIPLAI
AYLVVLWLLIRAGQLTDLRLLIVDAYQSTARITAMVVFILIGSTCFSVVFQGVDGGAWVEHLFTSLPGGWIGFLIVVNLF
IFFLAFFLDFFEIAFIVVPMLAPVAVKVLAPVVADSMGGNPEAAATAALVWFGVMLCVNMQTSFMHPPFGFALFYLRGIA
PKEVKSSDIYWGALPWVGLQLVMVLLVMFWPGMVTGLLDKGSLKHSNSAEVSIPLGGQDDGKPGGASSPGTLELPSGGDS
SEPVAPSFQFEKSK

Sequences:

>Translated_574_residues
MIPLEYMPPLMFGGLVVFMLIGFPVAFSLSAVGLAFGFLAIEWGYFPVQFLQAVPSRVFGSVLSNELLLAIPFFTFMGAI
LEKCGLAEDMLDSMGQLFGPVRGGLGYSVIIVGFILGAITGTVAAQVIAMAMISLPVMMRYRYNMKYATGVLAASGTITQ
LVPPSLVLVVLADQLKTPAGSADVGSMYLGAWGPSVIQIALFALYTFVLTRIKPDWLPPVPEEARTLRGWALWRTCLRGI
IPCAVLIFLVLGTIMLGIATPTESGAMGAVGALVLAVIRDKGFNKIDRNIYRLGLLATLVAAAVGVFAFGSHAFRIPLAI
AYLVVLWLLIRAGQLTDLRLLIVDAYQSTARITAMVVFILIGSTCFSVVFQGVDGGAWVEHLFTSLPGGWIGFLIVVNLF
IFFLAFFLDFFEIAFIVVPMLAPVAVKVLAPVVADSMGGNPEAAATAALVWFGVMLCVNMQTSFMHPPFGFALFYLRGIA
PKEVKSSDIYWGALPWVGLQLVMVLLVMFWPGMVTGLLDKGSLKHSNSAEVSIPLGGQDDGKPGGASSPGTLELPSGGDS
SEPVAPSFQFEKSK
>Mature_574_residues
MIPLEYMPPLMFGGLVVFMLIGFPVAFSLSAVGLAFGFLAIEWGYFPVQFLQAVPSRVFGSVLSNELLLAIPFFTFMGAI
LEKCGLAEDMLDSMGQLFGPVRGGLGYSVIIVGFILGAITGTVAAQVIAMAMISLPVMMRYRYNMKYATGVLAASGTITQ
LVPPSLVLVVLADQLKTPAGSADVGSMYLGAWGPSVIQIALFALYTFVLTRIKPDWLPPVPEEARTLRGWALWRTCLRGI
IPCAVLIFLVLGTIMLGIATPTESGAMGAVGALVLAVIRDKGFNKIDRNIYRLGLLATLVAAAVGVFAFGSHAFRIPLAI
AYLVVLWLLIRAGQLTDLRLLIVDAYQSTARITAMVVFILIGSTCFSVVFQGVDGGAWVEHLFTSLPGGWIGFLIVVNLF
IFFLAFFLDFFEIAFIVVPMLAPVAVKVLAPVVADSMGGNPEAAATAALVWFGVMLCVNMQTSFMHPPFGFALFYLRGIA
PKEVKSSDIYWGALPWVGLQLVMVLLVMFWPGMVTGLLDKGSLKHSNSAEVSIPLGGQDDGKPGGASSPGTLELPSGGDS
SEPVAPSFQFEKSK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 61367; Mature: 61367

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]