Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 94311670

GI number: 94311670

Start: 2974018

End: 2974854

Strand: Reverse

Name: plsC [H]

Synonym: Rmet_2738

Alternate gene names: 94311670

Gene position: 2974854-2974018 (Counterclockwise)

Preceding gene: 94311671

Following gene: 94311669

Centisome position: 75.73

GC content: 64.87

Gene sequence:

>837_bases
ATGATCTGGTTACGCAAGGCGCGGCTGACATTTCACCTGCTGCGTGGGGTGCTGTTCTGTGCCACTGTCTTTCCGTGGGC
GAGCGCGCGTCTGCGCGAACGTCTGATCCGAGCATGGTCCCGCAAGCTCCTGGCCATCTGCGGCATCGAGGTGGAAGTCT
TGGGCCTGGCGCCAGGGCAGGCGGCCCCCAAAGGCGCAATGCTGGTGTCGAACCATATCTCGTGGCTCGACATCTATGTC
ATCCATAGCTGGCAGCCCGTGCGCTTCGTCGCCAAGTCGGAGATCCGCAACTGGCCCGTAGTTGGCTGGCTGTGCGACAA
GACCGGCACGATCTTTATCGAGCGCGCCCGCAAGCGCGACGCGCACCGAGTGCTCCACCACATCACCGAAGTGATGCAGC
AAGGCGACCTGGTGTGCGTGTTCCCCGAGGGCACGACCACCGATGGCAGCAAGGTGCTGCCGTTTCACGCGAATTTGATG
CAGGCGCCAGTGGCCGGGAAACTGCCGGTGCAGCCGGTAGGGTTGTCCTACCTGGACGCGGCAACTGGCAAGCCGACGCT
GGCACCGGCCTACATCGACGACATATCGCTGGTGCAGTGCCTGAACGCTATTCTCAAGTCGCCACCGATCAAGGCGAGGC
TGGTGATCGGGCCGCAGTTGCATGCTGCATCAGCCGGACGAAGGGAGCTGGCGGAGTCGGCGCGGGAGGTGGTGACGCAT
CTGGTGGAGGGCGCGCATGAGGCGGCCCACGGTGCTGCCGAGGCATTTCATTCCCTGCCAGTCGCGGCAACGCCGCCGGT
CCTGACGTCGGTCGCCGCGCCTGCCGCAGGCCACTGA

Upstream 100 bases:

>100_bases
CGAGATGGAAGGGCGTGTGCGTACGACGCTGGTCTGCGGCCAGGTCGTCTACGAACAGCGCTGACAGGCCGGGCGCCATC
GAGGCAACACGGGGTCGACG

Downstream 100 bases:

>100_bases
CTCGTGCCGGCCAAAGGTAAATTTTGATTCCACCAACCCTTCTGTTGAGGGGTAAATAGATGAAAACCCTGTCGATGCAC
TTCGTGTATTGTTACGTTTT

Product: 1-acylglycerol-3-phosphate O-acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MIWLRKARLTFHLLRGVLFCATVFPWASARLRERLIRAWSRKLLAICGIEVEVLGLAPGQAAPKGAMLVSNHISWLDIYV
IHSWQPVRFVAKSEIRNWPVVGWLCDKTGTIFIERARKRDAHRVLHHITEVMQQGDLVCVFPEGTTTDGSKVLPFHANLM
QAPVAGKLPVQPVGLSYLDAATGKPTLAPAYIDDISLVQCLNAILKSPPIKARLVIGPQLHAASAGRRELAESAREVVTH
LVEGAHEAAHGAAEAFHSLPVAATPPVLTSVAAPAAGH

Sequences:

>Translated_278_residues
MIWLRKARLTFHLLRGVLFCATVFPWASARLRERLIRAWSRKLLAICGIEVEVLGLAPGQAAPKGAMLVSNHISWLDIYV
IHSWQPVRFVAKSEIRNWPVVGWLCDKTGTIFIERARKRDAHRVLHHITEVMQQGDLVCVFPEGTTTDGSKVLPFHANLM
QAPVAGKLPVQPVGLSYLDAATGKPTLAPAYIDDISLVQCLNAILKSPPIKARLVIGPQLHAASAGRRELAESAREVVTH
LVEGAHEAAHGAAEAFHSLPVAATPPVLTSVAAPAAGH
>Mature_278_residues
MIWLRKARLTFHLLRGVLFCATVFPWASARLRERLIRAWSRKLLAICGIEVEVLGLAPGQAAPKGAMLVSNHISWLDIYV
IHSWQPVRFVAKSEIRNWPVVGWLCDKTGTIFIERARKRDAHRVLHHITEVMQQGDLVCVFPEGTTTDGSKVLPFHANLM
QAPVAGKLPVQPVGLSYLDAATGKPTLAPAYIDDISLVQCLNAILKSPPIKARLVIGPQLHAASAGRRELAESAREVVTH
LVEGAHEAAHGAAEAFHSLPVAATPPVLTSVAAPAAGH

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320151, Length=145, Percent_Identity=28.9655172413793, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364648, Length=185, Percent_Identity=31.3513513513514, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24582856, Length=185, Percent_Identity=31.3513513513514, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24582854, Length=185, Percent_Identity=31.3513513513514, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 30188; Mature: 30188

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWLRKARLTFHLLRGVLFCATVFPWASARLRERLIRAWSRKLLAICGIEVEVLGLAPGQ
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
AAPKGAMLVSNHISWLDIYVIHSWQPVRFVAKSEIRNWPVVGWLCDKTGTIFIERARKRD
CCCCCCEEECCCCCEEEEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEHHHHHH
AHRVLHHITEVMQQGDLVCVFPEGTTTDGSKVLPFHANLMQAPVAGKLPVQPVGLSYLDA
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEHHHHHHCCCCCCCCCCCCCCHHHHC
ATGKPTLAPAYIDDISLVQCLNAILKSPPIKARLVIGPQLHAASAGRRELAESAREVVTH
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LVEGAHEAAHGAAEAFHSLPVAATPPVLTSVAAPAAGH
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MIWLRKARLTFHLLRGVLFCATVFPWASARLRERLIRAWSRKLLAICGIEVEVLGLAPGQ
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
AAPKGAMLVSNHISWLDIYVIHSWQPVRFVAKSEIRNWPVVGWLCDKTGTIFIERARKRD
CCCCCCEEECCCCCEEEEEEEECCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEHHHHHH
AHRVLHHITEVMQQGDLVCVFPEGTTTDGSKVLPFHANLMQAPVAGKLPVQPVGLSYLDA
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEHHHHHHCCCCCCCCCCCCCCHHHHC
ATGKPTLAPAYIDDISLVQCLNAILKSPPIKARLVIGPQLHAASAGRRELAESAREVVTH
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LVEGAHEAAHGAAEAFHSLPVAATPPVLTSVAAPAAGH
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8748025 [H]