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The map label for this gene is ndh [H]

Identifier: 94311559

GI number: 94311559

Start: 2854066

End: 2855469

Strand: Reverse

Name: ndh [H]

Synonym: Rmet_2623

Alternate gene names: 94311559

Gene position: 2855469-2854066 (Counterclockwise)

Preceding gene: 94311560

Following gene: 94311558

Centisome position: 72.69

GC content: 66.17

Gene sequence:

>1404_bases
ATGAGTCACGCATACGACAAAGAGGACAGCACGCAGAGGGAGGCGGCAACCGTAAGTACTCAGCCCCGCACGGTGGCACG
ATCGGAGAAGCAGGCACACCGGATCATCGTGGTCGGTGGCGGAGCCGGCGGGCTCGAGCTTGTCACGCGGTTGGGCGACA
AGCTTGGCAAGTCCGGCACGGCGCAGGTGACGCTGGTCGACCGCTCGCCCACGCACATCTGGAAGCCGCTGCTGCACGAG
GTGGCGGCGGGCAGCATGGACCCGAACACGCATCAGCTCGAGTACGTGGCCCAGGCGCGTTGGCACTACTTCGAGTTCCA
GCAAGGCGAACTGACCGGCATCGACCGGGAGCGCAAGCTTGTGAAGGTGGCGGCGTGCCTCGATCAGGATGGCGCGGAAT
TGCTGCCTGCCCGGGAATTGCCGTATGACACGCTCGTGCTCGCCATCGGTTGCGTCACGCATTTCTTCGGTGTGCCTGGA
GCAGCCGAGAACGCGATCGCGCTCGATACGGTCGATCAGGCAGAGCGCTTCCGGCGCAAGCTGATTGCCGCGTGCGTGCG
CGCGCAGAACGGCCGGGGCCGAGTCGGGGAGGATGGCCGCCCACGGGTCGACGTGGCGATCATCGGCGCCGGCGCGACGG
GGGTGGAACTGTCAGCGGAGTTGCGCAATACAGCGCACGTGCTCAATGCGTACGGGCTGCACCAGCTCGATCCGCGTCGC
GACGTACGCATCCATATCGTCGAGGCGGGCCCGCGCATCCTGCCGGCGCTGACGGAGCGTGTATCGGCCGAGACAACCAA
GCTGCTGCGCAAGCTCGATGTCGACGTGTTCACTTCGGAGCGCGTGACCGAAGTCACGAAGGACGCCGTGCTGACTGCCA
GCGGCAAGCATGTCGATGCCGATCTGACGGTGTGGGCGGCGGGTATTACCGCGCCGGGTGTGCTGCGCACGCTCGGCCTG
CCGGTCAGCAAGATGGGCCAGATCGTCGTGGGCCCGACGCTGCAGTGCGAGACGGATCCGGACATCTTCGCGTTCGGCGA
TTGCGCTGCCGCGCCGTGGCCCGAGAAGCAGACCACAGTGCCGCCGCGCGCTCAGGCCGCGCACCAGCAGGCAACATTCC
TCTATGACGCGATTCGCGCGCGGCTGGCTGGCAAGCCGCTGCCGAAGTTCGGCTTCAAGGACTTCGGCTCGCTGGTGTCG
TTGGGCCACTTCAGCGCCGTGGGCAGTCTGATGGGTGGCCTGATCGGTGGTTCGATGTTCATCGAGGGGCTGTTCGCGCG
CTTCATGTACACGTCGCTGTACCGGATGCATGTACTGGCGCTGCATGGGGCCATTGGCATGGGGCTGGACACCATCACGC
ACTGGCTGCGCAGCAAGACCAGCCCGCGCGTGAAGCTGCACTAG

Upstream 100 bases:

>100_bases
CAAGAAATGCTGCAAGAACATCGGCTTCGCGGCGCAAGACGACAATAGAAAGTCGCCGACGAGGCCTGCCGGTTTTCAAA
TTGAAAACATCGGGTAGACC

Downstream 100 bases:

>100_bases
GCGCAGCGGGCGGAGGCCGGCGCCGCGCGGGATGCGTGCCGCCGGCCCCACTTGGTCCAGGATTGCTTAGAATTGGCGGC
GATGTCTGCATCACTTACCT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSHAYDKEDSTQREAATVSTQPRTVARSEKQAHRIIVVGGGAGGLELVTRLGDKLGKSGTAQVTLVDRSPTHIWKPLLHE
VAAGSMDPNTHQLEYVAQARWHYFEFQQGELTGIDRERKLVKVAACLDQDGAELLPARELPYDTLVLAIGCVTHFFGVPG
AAENAIALDTVDQAERFRRKLIAACVRAQNGRGRVGEDGRPRVDVAIIGAGATGVELSAELRNTAHVLNAYGLHQLDPRR
DVRIHIVEAGPRILPALTERVSAETTKLLRKLDVDVFTSERVTEVTKDAVLTASGKHVDADLTVWAAGITAPGVLRTLGL
PVSKMGQIVVGPTLQCETDPDIFAFGDCAAAPWPEKQTTVPPRAQAAHQQATFLYDAIRARLAGKPLPKFGFKDFGSLVS
LGHFSAVGSLMGGLIGGSMFIEGLFARFMYTSLYRMHVLALHGAIGMGLDTITHWLRSKTSPRVKLH

Sequences:

>Translated_467_residues
MSHAYDKEDSTQREAATVSTQPRTVARSEKQAHRIIVVGGGAGGLELVTRLGDKLGKSGTAQVTLVDRSPTHIWKPLLHE
VAAGSMDPNTHQLEYVAQARWHYFEFQQGELTGIDRERKLVKVAACLDQDGAELLPARELPYDTLVLAIGCVTHFFGVPG
AAENAIALDTVDQAERFRRKLIAACVRAQNGRGRVGEDGRPRVDVAIIGAGATGVELSAELRNTAHVLNAYGLHQLDPRR
DVRIHIVEAGPRILPALTERVSAETTKLLRKLDVDVFTSERVTEVTKDAVLTASGKHVDADLTVWAAGITAPGVLRTLGL
PVSKMGQIVVGPTLQCETDPDIFAFGDCAAAPWPEKQTTVPPRAQAAHQQATFLYDAIRARLAGKPLPKFGFKDFGSLVS
LGHFSAVGSLMGGLIGGSMFIEGLFARFMYTSLYRMHVLALHGAIGMGLDTITHWLRSKTSPRVKLH
>Mature_466_residues
SHAYDKEDSTQREAATVSTQPRTVARSEKQAHRIIVVGGGAGGLELVTRLGDKLGKSGTAQVTLVDRSPTHIWKPLLHEV
AAGSMDPNTHQLEYVAQARWHYFEFQQGELTGIDRERKLVKVAACLDQDGAELLPARELPYDTLVLAIGCVTHFFGVPGA
AENAIALDTVDQAERFRRKLIAACVRAQNGRGRVGEDGRPRVDVAIIGAGATGVELSAELRNTAHVLNAYGLHQLDPRRD
VRIHIVEAGPRILPALTERVSAETTKLLRKLDVDVFTSERVTEVTKDAVLTASGKHVDADLTVWAAGITAPGVLRTLGLP
VSKMGQIVVGPTLQCETDPDIFAFGDCAAAPWPEKQTTVPPRAQAAHQQATFLYDAIRARLAGKPLPKFGFKDFGSLVSL
GHFSAVGSLMGGLIGGSMFIEGLFARFMYTSLYRMHVLALHGAIGMGLDTITHWLRSKTSPRVKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=435, Percent_Identity=49.4252873563218, Blast_Score=394, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6320118, Length=478, Percent_Identity=24.2677824267782, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323515, Length=471, Percent_Identity=24.416135881104, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323794, Length=458, Percent_Identity=22.2707423580786, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 50545; Mature: 50413

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHAYDKEDSTQREAATVSTQPRTVARSEKQAHRIIVVGGGAGGLELVTRLGDKLGKSGT
CCCCCCCCCCCHHHHHCCCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCC
AQVTLVDRSPTHIWKPLLHEVAAGSMDPNTHQLEYVAQARWHYFEFQQGELTGIDRERKL
EEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCHHHHH
VKVAACLDQDGAELLPARELPYDTLVLAIGCVTHFFGVPGAAENAIALDTVDQAERFRRK
HHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHH
LIAACVRAQNGRGRVGEDGRPRVDVAIIGAGATGVELSAELRNTAHVLNAYGLHQLDPRR
HHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
DVRIHIVEAGPRILPALTERVSAETTKLLRKLDVDVFTSERVTEVTKDAVLTASGKHVDA
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHEEEECCCCCCC
DLTVWAAGITAPGVLRTLGLPVSKMGQIVVGPTLQCETDPDIFAFGDCAAAPWPEKQTTV
CEEEEEECCCCCHHHHHHCCCHHHCCCEEECCEEEECCCCCEEEECCCCCCCCCCCCCCC
PPRAQAAHQQATFLYDAIRARLAGKPLPKFGFKDFGSLVSLGHFSAVGSLMGGLIGGSMF
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEGLFARFMYTSLYRMHVLALHGAIGMGLDTITHWLRSKTSPRVKLH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEECC
>Mature Secondary Structure 
SHAYDKEDSTQREAATVSTQPRTVARSEKQAHRIIVVGGGAGGLELVTRLGDKLGKSGT
CCCCCCCCCCHHHHHCCCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCC
AQVTLVDRSPTHIWKPLLHEVAAGSMDPNTHQLEYVAQARWHYFEFQQGELTGIDRERKL
EEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCHHHHH
VKVAACLDQDGAELLPARELPYDTLVLAIGCVTHFFGVPGAAENAIALDTVDQAERFRRK
HHHHHHHCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHH
LIAACVRAQNGRGRVGEDGRPRVDVAIIGAGATGVELSAELRNTAHVLNAYGLHQLDPRR
HHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
DVRIHIVEAGPRILPALTERVSAETTKLLRKLDVDVFTSERVTEVTKDAVLTASGKHVDA
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHEEEECCCCCCC
DLTVWAAGITAPGVLRTLGLPVSKMGQIVVGPTLQCETDPDIFAFGDCAAAPWPEKQTTV
CEEEEEECCCCCHHHHHHCCCHHHCCCEEECCEEEECCCCCEEEECCCCCCCCCCCCCCC
PPRAQAAHQQATFLYDAIRARLAGKPLPKFGFKDFGSLVSLGHFSAVGSLMGGLIGGSMF
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEGLFARFMYTSLYRMHVLALHGAIGMGLDTITHWLRSKTSPRVKLH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]