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The map label for this gene is srlR [H]

Identifier: 94311527

GI number: 94311527

Start: 2817590

End: 2818366

Strand: Direct

Name: srlR [H]

Synonym: Rmet_2591

Alternate gene names: 94311527

Gene position: 2817590-2818366 (Clockwise)

Preceding gene: 94311526

Following gene: 94311529

Centisome position: 71.73

GC content: 67.82

Gene sequence:

>777_bases
ATGAAAGCCGCCGACCGCCGCCGCGCCATCCTCGAACTCGTACTGTCCGGCGAGGATGCCAACGTTGAACGGTTGACCAG
CAACCTCGGCGTATCCGAAGCAACGGTGCGCCGCGACCTCACCGCGCTGGCACGCGAAGGGCGCATCGTACGCACCTACG
GCGGTGCCGCACCGCTGATGCAGATCGGCGGACACGAACCCGAGGCTTCGCTCGAGGAACGCAAGGCACTGCAACGCGAC
CAGAAAGAGTCGATCGCGCGCATGGCGGCGACCTTTGTCGACGACGGTGATGCCGTGCTGCTCGATAGCGGCACCACGGC
GGCCGCGCTGGCCCGGATGCTCGCCGCGCGTTCAGACCTGCATGTCTACACGACGAACCTGCTCGTGGTCACCGCCCTGG
TCGGCCTGCCCGAAGTCCGCGTCACGCTGATCGGCGGCGATGTGCGGCCGTCGAGCATGGGCACGTTCGGCCCGCTGGCA
CAGTTGGCGCTGTCGCGCATCAGCGTCGACAAGGCATTCCTGGGCGCCGACGGTGTCGTGGCTGGCGTGGGCCTGTGCGA
GGCCAGCGCCGAACAGGCTTATCTGAAGGAATGCATCATCCGGCAGGCCGCCGAGATCTTCGTGCTGGCCGACTCGACCA
AGCTGGGCCGCGCCCGCCAGCAGCACTGGACCCCACTGGAACGCGGATGGACGCTGGTGACGGATGGCGACGCCACCGCC
GACCAGCTCGAACCGTTCCGCGCACTGAAGCAGGTGCGCGTGGCGGTCGCGAATTAG

Upstream 100 bases:

>100_bases
GCAGGACGGCGGCCCTGCCGCCCTGCCACACAGCTTGAGCCAGCCACCGCTGCGGTAAGATCGGGGATCGTTTTCGATCC
CCTTTTCTCTTTTCCCATCC

Downstream 100 bases:

>100_bases
CATCGCGCCACCCGCGCTTACGCATCTGCCCTGCGGCGCTCAGCCGCGACGATGCCCGTTGTGCTTGTCGTGGTAGATCT
GGCCGCTGGCATGGTTCTCG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKAADRRRAILELVLSGEDANVERLTSNLGVSEATVRRDLTALAREGRIVRTYGGAAPLMQIGGHEPEASLEERKALQRD
QKESIARMAATFVDDGDAVLLDSGTTAAALARMLAARSDLHVYTTNLLVVTALVGLPEVRVTLIGGDVRPSSMGTFGPLA
QLALSRISVDKAFLGADGVVAGVGLCEASAEQAYLKECIIRQAAEIFVLADSTKLGRARQQHWTPLERGWTLVTDGDATA
DQLEPFRALKQVRVAVAN

Sequences:

>Translated_258_residues
MKAADRRRAILELVLSGEDANVERLTSNLGVSEATVRRDLTALAREGRIVRTYGGAAPLMQIGGHEPEASLEERKALQRD
QKESIARMAATFVDDGDAVLLDSGTTAAALARMLAARSDLHVYTTNLLVVTALVGLPEVRVTLIGGDVRPSSMGTFGPLA
QLALSRISVDKAFLGADGVVAGVGLCEASAEQAYLKECIIRQAAEIFVLADSTKLGRARQQHWTPLERGWTLVTDGDATA
DQLEPFRALKQVRVAVAN
>Mature_258_residues
MKAADRRRAILELVLSGEDANVERLTSNLGVSEATVRRDLTALAREGRIVRTYGGAAPLMQIGGHEPEASLEERKALQRD
QKESIARMAATFVDDGDAVLLDSGTTAAALARMLAARSDLHVYTTNLLVVTALVGLPEVRVTLIGGDVRPSSMGTFGPLA
QLALSRISVDKAFLGADGVVAGVGLCEASAEQAYLKECIIRQAAEIFVLADSTKLGRARQQHWTPLERGWTLVTDGDATA
DQLEPFRALKQVRVAVAN

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=236, Percent_Identity=30.9322033898305, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789829, Length=221, Percent_Identity=32.579185520362, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789519, Length=244, Percent_Identity=30.327868852459, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788069, Length=217, Percent_Identity=29.4930875576037, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787540, Length=239, Percent_Identity=27.1966527196653, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI226510968, Length=235, Percent_Identity=28.5106382978723, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790753, Length=243, Percent_Identity=27.9835390946502, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87082344, Length=209, Percent_Identity=28.2296650717703, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789170, Length=221, Percent_Identity=27.6018099547511, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790635, Length=249, Percent_Identity=24.8995983935743, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787063, Length=215, Percent_Identity=27.4418604651163, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27574; Mature: 27574

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAADRRRAILELVLSGEDANVERLTSNLGVSEATVRRDLTALAREGRIVRTYGGAAPLM
CCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCHHH
QIGGHEPEASLEERKALQRDQKESIARMAATFVDDGDAVLLDSGTTAAALARMLAARSDL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCC
HVYTTNLLVVTALVGLPEVRVTLIGGDVRPSSMGTFGPLAQLALSRISVDKAFLGADGVV
EEHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
AGVGLCEASAEQAYLKECIIRQAAEIFVLADSTKLGRARQQHWTPLERGWTLVTDGDATA
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCHHHHCEEEEECCCCCH
DQLEPFRALKQVRVAVAN
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAADRRRAILELVLSGEDANVERLTSNLGVSEATVRRDLTALAREGRIVRTYGGAAPLM
CCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCHHH
QIGGHEPEASLEERKALQRDQKESIARMAATFVDDGDAVLLDSGTTAAALARMLAARSDL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCC
HVYTTNLLVVTALVGLPEVRVTLIGGDVRPSSMGTFGPLAQLALSRISVDKAFLGADGVV
EEHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
AGVGLCEASAEQAYLKECIIRQAAEIFVLADSTKLGRARQQHWTPLERGWTLVTDGDATA
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCHHHHCEEEEECCCCCH
DQLEPFRALKQVRVAVAN
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]