| Definition | Cupriavidus metallidurans CH34 chromosome, complete genome. |
|---|---|
| Accession | NC_007973 |
| Length | 3,928,089 |
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The map label for this gene is fabG [H]
Identifier: 94311462
GI number: 94311462
Start: 2748694
End: 2749563
Strand: Reverse
Name: fabG [H]
Synonym: Rmet_2526
Alternate gene names: 94311462
Gene position: 2749563-2748694 (Counterclockwise)
Preceding gene: 94311463
Following gene: 94311461
Centisome position: 70.0
GC content: 64.48
Gene sequence:
>870_bases GTGGCCCCCGCATCCAGCATCGAAAGGAACCATGCAATGAGCAAGCTCGCAGGAAAGTCCGCCATCGTCACCGGCTCGGG CCGTGGCATCGGCCGTGAAGTCGCAATGAAACTGGCGGCAGAAGGCGCCCGTGTGGTCGTGAACGACCTGGACGCCGATC CGGCGCAAGAAGTGGTGGAGCTGATCCGTGCAAACGGCGGCGAAGCCGTGGCCTGCGTCGGCAGCGTGACCGCGCCTGAT TTTGCCGACCGCCTCATCAAGACCACGGTCGACAGTTTCAAGGGCATCGACATCATCGTCAACAACGCCGGCTACACCTG GGACAACGTGATCCAGAAGATGACCGACGAGCAGTGGTACGCCATACTCGACTGCCACTTGACCGCACCGTTCCGCATCC TGCGTGCCGCACAGCCCGTCATCAGCGCTGCGGCCAAGGCCGAAGCCGCCGAAGGCCGCGAAGTCTTCCGCAAGGTCGTC AACATTTCCTCGGGTGCGGCCGGTGGCAATGCCGGGCAGTCGAACTACTCCGCCGCCAAGGCCGGCATCCTGGGCATGAC CAAGACGCTGGCCAAGGAGTGGGGCCGCCTGAAGGTCAACGTCAACGCCGTGGCGTTCGGTCTGATCGAAACGCGCCTCA CCCAGGCGCTGGCGGCGGACCAGAGCAAGAGCGTCAGTATCGAAGGCCGTGAGATCAAGGTCGGCGTGCAGCAGGCAATG CTCGACGGCGCCAGCCGCATGATTCCGGTCGGCCGCGCGGGCAGGGCCGAAGAGGCAGCTGGCGCTGTCTATCTGCTTTG CACGCCGGAGTCGAACTTCCTGTCCGGCCAGGTTCTGTACTGTGGCGGTGGCCCTGGCGCAAACTTCTGA
Upstream 100 bases:
>100_bases ACGAACCAGTACGGCGAAGAGAAGTTGCTTGGCGAAGCCGTGGTGGCGCTGCACTGAGTCACCAGGCCGAACTGCCATCC ATTCGCGGACGGGCCATGAC
Downstream 100 bases:
>100_bases TCGGATCGGGGCCACAGCCTTGCCTGCCGGTGGCGGGCAAGGCGCGCCTGGCTGCCAAAGCGGCCCTTCAAGAGGCTCGC TGCCGCACGTGCGGATAACG
Product: 3-Oxoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase 1 [H]
Number of amino acids: Translated: 289; Mature: 288
Protein sequence:
>289_residues MAPASSIERNHAMSKLAGKSAIVTGSGRGIGREVAMKLAAEGARVVVNDLDADPAQEVVELIRANGGEAVACVGSVTAPD FADRLIKTTVDSFKGIDIIVNNAGYTWDNVIQKMTDEQWYAILDCHLTAPFRILRAAQPVISAAAKAEAAEGREVFRKVV NISSGAAGGNAGQSNYSAAKAGILGMTKTLAKEWGRLKVNVNAVAFGLIETRLTQALAADQSKSVSIEGREIKVGVQQAM LDGASRMIPVGRAGRAEEAAGAVYLLCTPESNFLSGQVLYCGGGPGANF
Sequences:
>Translated_289_residues MAPASSIERNHAMSKLAGKSAIVTGSGRGIGREVAMKLAAEGARVVVNDLDADPAQEVVELIRANGGEAVACVGSVTAPD FADRLIKTTVDSFKGIDIIVNNAGYTWDNVIQKMTDEQWYAILDCHLTAPFRILRAAQPVISAAAKAEAAEGREVFRKVV NISSGAAGGNAGQSNYSAAKAGILGMTKTLAKEWGRLKVNVNAVAFGLIETRLTQALAADQSKSVSIEGREIKVGVQQAM LDGASRMIPVGRAGRAEEAAGAVYLLCTPESNFLSGQVLYCGGGPGANF >Mature_288_residues APASSIERNHAMSKLAGKSAIVTGSGRGIGREVAMKLAAEGARVVVNDLDADPAQEVVELIRANGGEAVACVGSVTAPDF ADRLIKTTVDSFKGIDIIVNNAGYTWDNVIQKMTDEQWYAILDCHLTAPFRILRAAQPVISAAAKAEAAEGREVFRKVVN ISSGAAGGNAGQSNYSAAKAGILGMTKTLAKEWGRLKVNVNAVAFGLIETRLTQALAADQSKSVSIEGREIKVGVQQAML DGASRMIPVGRAGRAEEAAGAVYLLCTPESNFLSGQVLYCGGGPGANF
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=281, Percent_Identity=31.6725978647687, Blast_Score=122, Evalue=5e-28, Organism=Homo sapiens, GI4504505, Length=200, Percent_Identity=37.5, Blast_Score=119, Evalue=5e-27, Organism=Homo sapiens, GI32483357, Length=270, Percent_Identity=31.1111111111111, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI19923817, Length=274, Percent_Identity=26.6423357664234, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI126723750, Length=276, Percent_Identity=27.1739130434783, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI40254992, Length=267, Percent_Identity=28.0898876404494, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI5031737, Length=265, Percent_Identity=25.6603773584906, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI7705925, Length=272, Percent_Identity=28.3088235294118, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI126723191, Length=202, Percent_Identity=30.1980198019802, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI59889578, Length=245, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=9e-11, Organism=Escherichia coli, GI1787335, Length=268, Percent_Identity=36.1940298507463, Blast_Score=149, Evalue=2e-37, Organism=Escherichia coli, GI1790717, Length=273, Percent_Identity=27.8388278388278, Blast_Score=105, Evalue=5e-24, Organism=Escherichia coli, GI1789208, Length=270, Percent_Identity=29.2592592592593, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI87082160, Length=285, Percent_Identity=29.8245614035088, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1787905, Length=275, Percent_Identity=32.7272727272727, Blast_Score=99, Evalue=5e-22, Organism=Escherichia coli, GI87082100, Length=272, Percent_Identity=26.4705882352941, Blast_Score=88, Evalue=8e-19, Organism=Escherichia coli, GI2367175, Length=275, Percent_Identity=30.5454545454545, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789378, Length=273, Percent_Identity=27.1062271062271, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1789057, Length=267, Percent_Identity=25.8426966292135, Blast_Score=69, Evalue=5e-13, Organism=Escherichia coli, GI1788459, Length=267, Percent_Identity=27.3408239700375, Blast_Score=67, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17555706, Length=274, Percent_Identity=32.8467153284672, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17568967, Length=216, Percent_Identity=36.1111111111111, Blast_Score=124, Evalue=4e-29, Organism=Caenorhabditis elegans, GI25147288, Length=271, Percent_Identity=34.3173431734317, Blast_Score=121, Evalue=5e-28, Organism=Caenorhabditis elegans, GI17562910, Length=282, Percent_Identity=31.5602836879433, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17560676, Length=276, Percent_Identity=29.7101449275362, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17561402, Length=276, Percent_Identity=26.8115942028986, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562904, Length=282, Percent_Identity=27.3049645390071, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17544670, Length=279, Percent_Identity=26.1648745519713, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560332, Length=288, Percent_Identity=29.5138888888889, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560150, Length=282, Percent_Identity=28.7234042553192, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17559104, Length=282, Percent_Identity=28.3687943262411, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17538486, Length=284, Percent_Identity=28.5211267605634, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17562906, Length=285, Percent_Identity=28.0701754385965, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17562990, Length=281, Percent_Identity=28.8256227758007, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI72000259, Length=283, Percent_Identity=26.1484098939929, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71994600, Length=271, Percent_Identity=25.830258302583, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17563726, Length=286, Percent_Identity=28.3216783216783, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17560220, Length=213, Percent_Identity=28.6384976525822, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71994604, Length=274, Percent_Identity=27.3722627737226, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17562908, Length=211, Percent_Identity=27.4881516587678, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17538480, Length=282, Percent_Identity=29.4326241134752, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17531453, Length=284, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI115534694, Length=274, Percent_Identity=27.007299270073, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17551412, Length=280, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=29.5336787564767, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=29.2929292929293, Blast_Score=65, Evalue=6e-11, Organism=Caenorhabditis elegans, GI193204405, Length=212, Percent_Identity=29.2452830188679, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=204, Percent_Identity=36.2745098039216, Blast_Score=120, Evalue=2e-28, Organism=Drosophila melanogaster, GI18859837, Length=213, Percent_Identity=35.6807511737089, Blast_Score=110, Evalue=8e-25, Organism=Drosophila melanogaster, GI24639444, Length=272, Percent_Identity=31.6176470588235, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI21355319, Length=276, Percent_Identity=26.8115942028986, Blast_Score=94, Evalue=8e-20, Organism=Drosophila melanogaster, GI23397609, Length=270, Percent_Identity=28.5185185185185, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24644339, Length=271, Percent_Identity=24.7232472324723, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI17737361, Length=206, Percent_Identity=29.126213592233, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24643142, Length=281, Percent_Identity=25.2669039145907, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI21357041, Length=274, Percent_Identity=25.5474452554745, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 30094; Mature: 29962
Theoretical pI: Translated: 7.93; Mature: 7.93
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAPASSIERNHAMSKLAGKSAIVTGSGRGIGREVAMKLAAEGARVVVNDLDADPAQEVVE CCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHH LIRANGGEAVACVGSVTAPDFADRLIKTTVDSFKGIDIIVNNAGYTWDNVIQKMTDEQWY HHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCEE AILDCHLTAPFRILRAAQPVISAAAKAEAAEGREVFRKVVNISSGAAGGNAGQSNYSAAK EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH AGILGMTKTLAKEWGRLKVNVNAVAFGLIETRLTQALAADQSKSVSIEGREIKVGVQQAM HHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEHHHHHHH LDGASRMIPVGRAGRAEEAAGAVYLLCTPESNFLSGQVLYCGGGPGANF HCCHHHEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCC >Mature Secondary Structure APASSIERNHAMSKLAGKSAIVTGSGRGIGREVAMKLAAEGARVVVNDLDADPAQEVVE CCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHH LIRANGGEAVACVGSVTAPDFADRLIKTTVDSFKGIDIIVNNAGYTWDNVIQKMTDEQWY HHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCEE AILDCHLTAPFRILRAAQPVISAAAKAEAAEGREVFRKVVNISSGAAGGNAGQSNYSAAK EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH AGILGMTKTLAKEWGRLKVNVNAVAFGLIETRLTQALAADQSKSVSIEGREIKVGVQQAM HHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEHHHHHHH LDGASRMIPVGRAGRAEEAAGAVYLLCTPESNFLSGQVLYCGGGPGANF HCCHHHEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]