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The map label for this gene is uup [H]

Identifier: 94311459

GI number: 94311459

Start: 2741991

End: 2743916

Strand: Reverse

Name: uup [H]

Synonym: Rmet_2523

Alternate gene names: 94311459

Gene position: 2743916-2741991 (Counterclockwise)

Preceding gene: 94311460

Following gene: 94311457

Centisome position: 69.85

GC content: 65.78

Gene sequence:

>1926_bases
ATGGCCCTGTTCTCCATTACCGATGCCCAGCTGGCTTTCGGCCACGTGGCGTTGCTCGACCACACCGATTTTTCCCTTGA
AGCCGGCGAACGTGTTGGCCTGATCGGCCGCAACGGCACGGGCAAGTCGTCCCTGCTGCGGATCGTGGCCGGAATGTCAG
CGCCCGACGATGGCCTGATCTCCCGCCAGAGCGGCGTGACGTGCGCCTATGTGTCGCAAGAGCCGCAGTTCGCGCCGGGC
TTGACCGTATTCGATGCGGTGAGCCAGGGCATGGGCGCAGCGCACGATCTGCTGCTGCGCTATGACGCTGCGCTCACCAA
GCTGGAAACCCACAACGACGAGGCCACCCTGGCCGAACTGCATCGCGTGCAGGCCGAACTTGATGCCGCCGACGCCTGGC
AGTTGCGCACCCGCGTGGAAACCACGCTGGCAAAGCTCGCGCTCGACCCGCATGTGCGCGTGGACGCGCTTTCTGGCGGT
CTGCAGAAGCGCGTGGCGCTGGCCCAGGGTCTGGTGGCCGAGCCGGACATCCTGCTGCTCGACGAGCCGACCAACCACCT
CGACGTGGAGGCCATCCGCTGGCTCGAAGACCTGCTGCTCGGGTTCCGCGGCAGCGTGCTGCTGATCACCCACGACCGCG
CGTTCCTGGATCGCGTGGCAACCCGCATCGTCGAACTCGATCGGGGCCGGCTGGTTTCGTTCCCGGGCAACTTTGCCGCC
TACCAGACGCGCAAGGCCGAACTGCTGGCCAACGAGGCCGTGGAGCAAGCCAAGTTCGACAAGCTGCTGGCGCAGGAAGA
AGTGTGGATCCGCAAGGGCGTGGAAGCACGCCGTACCCGCAGCGTGGCGCGGGTGCAGCGGCTGGTGACGATGCGGGCGG
AGCGCGCCTCGCGTCGCGAGGTGCAGGGCAACGTCAAGCTCGAGGTTTCGCAGGGCGAGCGTTCGGGCAAGATCGTGGCC
GAGTTGACTAACGTGTCGAAGGCTTATGGCGACAAGGCAGTCGTGCGCGACTTCACCGCGACGATCATGCGCGGCGACAA
GGTCGGCCTGATCGGGCCAAACGGCGTCGGCAAGACCACGCTGCTGCGGCTGATTCTGGGTGAACTGCCGCCCGACAGCG
GCACGGTGCGCAATGGCAGCAATCTGCAGGTGGCGTACTTCGACCAGATGCGTACCTCGCTGGATCTGGAGAAGTCGCTC
GCGGACACCATCAGCCCGGGTAGCGACTGGGTCGAGGTCAACGGCCAGCGCAAGCACGTGATGAGCTACCTGGGCGACTT
CCTGTTCGCGCCCGAACGCGCGCGGTCGCCGGTCAAGTCGCTGTCGGGCGGCGAGCGCAACCGGCTGCTGCTGGCGCGGT
TGTTCGCGCGACCCGCGAATGTGCTGGTGCTGGACGAACCGACCAACGACCTGGACATCGACACGCTCGAACTGCTGGAA
GAACTCCTACAGGACTACAGCGGCACGGTGTTCCTGGTTTCGCACGATCGTGCGTTCCTGGACAACGTGGTGACCTCCAC
GATCGCTGCCGAAGGCGATGGCATGTGGCGCGAATCGGTAGGCGGTTACTCGGACTGGCTGGAACAGTCGGCCCGTGCGC
AGGCGTTGCAGGCTGCCCGCGCTGAATCCAAGCAGGCTACGGAGGCGCCAAAGTCGGCCGCGCGCGAGGCGCGGGGCGCG
AATCGCACGGTCAAGCTGTCGTACAAGGAGCAGCGCGAACTCGACAGTCTGCCGGAACGTATCCAGTCGCTGGAGACCGA
GCAGAAGACCATCGGCGCGCAACTCGAGGACGGCTCGATGTACGCCACCGATCCGAAGCGGGCGGCCGATCTGGCCACGC
GTCACGACGAGATCGAGATGGAACTGCTTGAAGCACTCGAGCGCTGGGAAGTGCTGGAGAAGAAGACGAAGGGCGAGGGC
GCTTGA

Upstream 100 bases:

>100_bases
GTCATGCAGATCGGCAATGAACTTCTTTTCTCGGGGCACCTTATGGGTGCCGACGCCTGCGACTCGTCTACAATCTTGGG
CCTACTCAGTCGGACCCACC

Downstream 100 bases:

>100_bases
GCGTTGCCCTTGGTTTTCACCTTCTCTCCCACGGCGTGGGAGAGAGGGGCTGGTCGGTAGTCAATCCACTCATCCGCACC
ACGCCAGCACCATATTGGTC

Product: transposon excision ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MALFSITDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGTGKSSLLRIVAGMSAPDDGLISRQSGVTCAYVSQEPQFAPG
LTVFDAVSQGMGAAHDLLLRYDAALTKLETHNDEATLAELHRVQAELDAADAWQLRTRVETTLAKLALDPHVRVDALSGG
LQKRVALAQGLVAEPDILLLDEPTNHLDVEAIRWLEDLLLGFRGSVLLITHDRAFLDRVATRIVELDRGRLVSFPGNFAA
YQTRKAELLANEAVEQAKFDKLLAQEEVWIRKGVEARRTRSVARVQRLVTMRAERASRREVQGNVKLEVSQGERSGKIVA
ELTNVSKAYGDKAVVRDFTATIMRGDKVGLIGPNGVGKTTLLRLILGELPPDSGTVRNGSNLQVAYFDQMRTSLDLEKSL
ADTISPGSDWVEVNGQRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIDTLELLE
ELLQDYSGTVFLVSHDRAFLDNVVTSTIAAEGDGMWRESVGGYSDWLEQSARAQALQAARAESKQATEAPKSAAREARGA
NRTVKLSYKEQRELDSLPERIQSLETEQKTIGAQLEDGSMYATDPKRAADLATRHDEIEMELLEALERWEVLEKKTKGEG
A

Sequences:

>Translated_641_residues
MALFSITDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGTGKSSLLRIVAGMSAPDDGLISRQSGVTCAYVSQEPQFAPG
LTVFDAVSQGMGAAHDLLLRYDAALTKLETHNDEATLAELHRVQAELDAADAWQLRTRVETTLAKLALDPHVRVDALSGG
LQKRVALAQGLVAEPDILLLDEPTNHLDVEAIRWLEDLLLGFRGSVLLITHDRAFLDRVATRIVELDRGRLVSFPGNFAA
YQTRKAELLANEAVEQAKFDKLLAQEEVWIRKGVEARRTRSVARVQRLVTMRAERASRREVQGNVKLEVSQGERSGKIVA
ELTNVSKAYGDKAVVRDFTATIMRGDKVGLIGPNGVGKTTLLRLILGELPPDSGTVRNGSNLQVAYFDQMRTSLDLEKSL
ADTISPGSDWVEVNGQRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIDTLELLE
ELLQDYSGTVFLVSHDRAFLDNVVTSTIAAEGDGMWRESVGGYSDWLEQSARAQALQAARAESKQATEAPKSAAREARGA
NRTVKLSYKEQRELDSLPERIQSLETEQKTIGAQLEDGSMYATDPKRAADLATRHDEIEMELLEALERWEVLEKKTKGEG
A
>Mature_640_residues
ALFSITDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGTGKSSLLRIVAGMSAPDDGLISRQSGVTCAYVSQEPQFAPGL
TVFDAVSQGMGAAHDLLLRYDAALTKLETHNDEATLAELHRVQAELDAADAWQLRTRVETTLAKLALDPHVRVDALSGGL
QKRVALAQGLVAEPDILLLDEPTNHLDVEAIRWLEDLLLGFRGSVLLITHDRAFLDRVATRIVELDRGRLVSFPGNFAAY
QTRKAELLANEAVEQAKFDKLLAQEEVWIRKGVEARRTRSVARVQRLVTMRAERASRREVQGNVKLEVSQGERSGKIVAE
LTNVSKAYGDKAVVRDFTATIMRGDKVGLIGPNGVGKTTLLRLILGELPPDSGTVRNGSNLQVAYFDQMRTSLDLEKSLA
DTISPGSDWVEVNGQRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIDTLELLEE
LLQDYSGTVFLVSHDRAFLDNVVTSTIAAEGDGMWRESVGGYSDWLEQSARAQALQAARAESKQATEAPKSAAREARGAN
RTVKLSYKEQRELDSLPERIQSLETEQKTIGAQLEDGSMYATDPKRAADLATRHDEIEMELLEALERWEVLEKKTKGEGA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=536, Percent_Identity=32.2761194029851, Blast_Score=226, Evalue=6e-59,
Organism=Homo sapiens, GI10947135, Length=498, Percent_Identity=31.5261044176707, Blast_Score=192, Evalue=9e-49,
Organism=Homo sapiens, GI69354671, Length=498, Percent_Identity=31.5261044176707, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI27881506, Length=543, Percent_Identity=29.2817679558011, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI10947137, Length=543, Percent_Identity=29.2817679558011, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI9955963, Length=178, Percent_Identity=29.7752808988764, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1787182, Length=639, Percent_Identity=46.9483568075117, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI2367384, Length=534, Percent_Identity=37.4531835205993, Blast_Score=343, Evalue=2e-95,
Organism=Escherichia coli, GI1789751, Length=655, Percent_Identity=30.0763358778626, Blast_Score=258, Evalue=1e-69,
Organism=Escherichia coli, GI1787041, Length=535, Percent_Identity=32.1495327102804, Blast_Score=256, Evalue=4e-69,
Organism=Escherichia coli, GI1788165, Length=186, Percent_Identity=34.4086021505376, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI48995001, Length=519, Percent_Identity=25.2408477842004, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788506, Length=550, Percent_Identity=25.2727272727273, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693107, Length=564, Percent_Identity=22.5177304964539, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789891, Length=227, Percent_Identity=30.8370044052863, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789672, Length=252, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788761, Length=240, Percent_Identity=29.1666666666667, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786253, Length=235, Percent_Identity=31.063829787234, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787712, Length=204, Percent_Identity=31.8627450980392, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787758, Length=227, Percent_Identity=28.1938325991189, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994883, Length=253, Percent_Identity=24.1106719367589, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081791, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786872, Length=225, Percent_Identity=26.2222222222222, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081782, Length=183, Percent_Identity=31.1475409836066, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787164, Length=184, Percent_Identity=30.9782608695652, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790467, Length=197, Percent_Identity=29.9492385786802, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790190, Length=248, Percent_Identity=25.4032258064516, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=530, Percent_Identity=26.7924528301887, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17553372, Length=544, Percent_Identity=30.5147058823529, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17555318, Length=531, Percent_Identity=27.4952919020716, Blast_Score=184, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6320874, Length=543, Percent_Identity=28.5451197053407, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6321121, Length=550, Percent_Identity=28.3636363636364, Blast_Score=186, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6325030, Length=387, Percent_Identity=29.4573643410853, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6324314, Length=417, Percent_Identity=26.378896882494, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323278, Length=416, Percent_Identity=25.7211538461538, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24642252, Length=570, Percent_Identity=29.6491228070175, Blast_Score=215, Evalue=1e-55,
Organism=Drosophila melanogaster, GI18859989, Length=570, Percent_Identity=29.6491228070175, Blast_Score=215, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24666836, Length=537, Percent_Identity=30.3538175046555, Blast_Score=209, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24641342, Length=522, Percent_Identity=29.8850574712644, Blast_Score=201, Evalue=9e-52,
Organism=Drosophila melanogaster, GI116007184, Length=203, Percent_Identity=33.0049261083744, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221500365, Length=203, Percent_Identity=33.0049261083744, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574259, Length=208, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281361582, Length=191, Percent_Identity=31.413612565445, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 70465; Mature: 70333

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFSITDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGTGKSSLLRIVAGMSAPDDGLI
CEEEEECCHHHHHCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCC
SRQSGVTCAYVSQEPQFAPGLTVFDAVSQGMGAAHDLLLRYDAALTKLETHNDEATLAEL
CCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HRVQAELDAADAWQLRTRVETTLAKLALDPHVRVDALSGGLQKRVALAQGLVAEPDILLL
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCHHHHHHHHHHCCCCCCCEEEE
DEPTNHLDVEAIRWLEDLLLGFRGSVLLITHDRAFLDRVATRIVELDRGRLVSFPGNFAA
ECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCCHH
YQTRKAELLANEAVEQAKFDKLLAQEEVWIRKGVEARRTRSVARVQRLVTMRAERASRRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VQGNVKLEVSQGERSGKIVAELTNVSKAYGDKAVVRDFTATIMRGDKVGLIGPNGVGKTT
CCCCEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCHHH
LLRLILGELPPDSGTVRNGSNLQVAYFDQMRTSLDLEKSLADTISPGSDWVEVNGQRKHV
HHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHH
MSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIDTLELLE
HHHHHHHHCCCHHHCCHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHH
ELLQDYSGTVFLVSHDRAFLDNVVTSTIAAEGDGMWRESVGGYSDWLEQSARAQALQAAR
HHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
AESKQATEAPKSAAREARGANRTVKLSYKEQRELDSLPERIQSLETEQKTIGAQLEDGSM
HHHHHHHHCHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCE
YATDPKRAADLATRHDEIEMELLEALERWEVLEKKTKGEGA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALFSITDAQLAFGHVALLDHTDFSLEAGERVGLIGRNGTGKSSLLRIVAGMSAPDDGLI
EEEEECCHHHHHCEEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCC
SRQSGVTCAYVSQEPQFAPGLTVFDAVSQGMGAAHDLLLRYDAALTKLETHNDEATLAEL
CCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
HRVQAELDAADAWQLRTRVETTLAKLALDPHVRVDALSGGLQKRVALAQGLVAEPDILLL
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCHHHHHHHHHHCCCCCCCEEEE
DEPTNHLDVEAIRWLEDLLLGFRGSVLLITHDRAFLDRVATRIVELDRGRLVSFPGNFAA
ECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCCHH
YQTRKAELLANEAVEQAKFDKLLAQEEVWIRKGVEARRTRSVARVQRLVTMRAERASRRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VQGNVKLEVSQGERSGKIVAELTNVSKAYGDKAVVRDFTATIMRGDKVGLIGPNGVGKTT
CCCCEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCHHH
LLRLILGELPPDSGTVRNGSNLQVAYFDQMRTSLDLEKSLADTISPGSDWVEVNGQRKHV
HHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHH
MSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLDEPTNDLDIDTLELLE
HHHHHHHHCCCHHHCCHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHH
ELLQDYSGTVFLVSHDRAFLDNVVTSTIAAEGDGMWRESVGGYSDWLEQSARAQALQAAR
HHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
AESKQATEAPKSAAREARGANRTVKLSYKEQRELDSLPERIQSLETEQKTIGAQLEDGSM
HHHHHHHHCHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCE
YATDPKRAADLATRHDEIEMELLEALERWEVLEKKTKGEGA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]