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The map label for this gene is sohB [H]

Identifier: 94311372

GI number: 94311372

Start: 2644612

End: 2645775

Strand: Reverse

Name: sohB [H]

Synonym: Rmet_2436

Alternate gene names: 94311372

Gene position: 2645775-2644612 (Counterclockwise)

Preceding gene: 94311373

Following gene: 94311369

Centisome position: 67.36

GC content: 63.57

Gene sequence:

>1164_bases
ATGACAGAACAGCAAAATCCGCCGAACGAACCGGGTCAACCGCAAGAGCGCGCGGGCGACGACAGCAAGCTGGAGACGGC
AAAGCACGCCGAATTCCCGCTGGAGCGGGAACTGCAGGCTGGCGACGACGCGGCCAAGCGCGAAGCCGACGAGCGGCGCG
CCCGCCTGGCAGGCAAGGGCGGTCCGGTTGGTGGCAGCAGCGGCAGCGGTGGTGGCAGTGGTAGTGGCGGCTGGGAGCGC
GACGTGCTCGAGAAGGTGCTGATGGCCTCCCTGCGCGAGCAGCGCTCGGCGCGACGCTGGAAGATCTTCTTCCGCTTTCT
TACCCTCGCCATCGTTGCACTGATTCTCTACGCGGTGATCGACTTCAAGGGGGATGTGCTGAGTTCGACGAGCGGTCGCC
ATACCGCCATGGTCACGCTCGACGGCGAAATTGCCGCCGGCACCACGGCCAGCGCGGACTCTATCAACGCCGCGCTTCAG
GCGGCCTTCGAGGACACATCGGCAGCTGGCGTGATCCTGAAGATCAACTCGCCAGGCGGCTCGCCGGTACAGGCCGGCAT
CATCAACGACGAGATTCACCGCCTGCGCAAGCTGTATCCGGACAAGCCGTTCTACGTGGTGGTCGAGGAAATCTGCGCAT
CTGGCGGCTATTACGTGGCCGCCGCAGCCGACAAGATCTATGTCGACAAGGCCAGTATTGTTGGGTCGATCGGCGTGCTG
ATGGATGGCTTTGGCTTTACGGGCCTGATGGACAAGGTCGGCGTCCAGCGCCGCCTGTACACGTCAGGCGCCAATAAGGG
CATGCTCGATCCGTTCTCGCCGGAAGTGCCACGCCAGAAGGGCTACGCGGAGTCCATGCTCAAGGAGATCCACCAGCAGT
TCATCGACGTGGTGAAGGAAGGTCGTGGCGATCGGCTCAAGAACGATCCCGAACTGTTCTCGGGGCTCTTCTGGTCGGGT
GAGCGCGCTGTGGAGCTTGGGCTGGCCGATGGCCTGGGTAGCGCGGACTACGTGGCCCGGGACCTGTTCAAGGCCGAGGA
CATCGTCGACTACACGGTCAAGGAGAACATCGCCGAACGCATGGCCAAGCGCTTCGGCGCGGCCGCTGGATCGGCGGCGA
TGAAGTTGATGATGATGAGTGCAACCGTGCCTTCGGTGCGGTAA

Upstream 100 bases:

>100_bases
GCGAGGGCGCGGTCTTCTGGTTGCCTGAACCCCCATTTTTCCCGCTCGACGCCGAGTAAGGCGGAGCGGGACGTCATCTG
ACTTTATCGAGTCCATTCGC

Downstream 100 bases:

>100_bases
TCGGCGCGATGCGCCCATGCAAAAGCCCCCGATTTCCGGGGGCTTTTGTTTTTGTCTTACTGCGCCAGCAGCGAGAAGAT
CGCGGGGCGCTTGTGCAGGT

Product: peptidase S49, periplasmic serine protease (ClpP class)

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTEQQNPPNEPGQPQERAGDDSKLETAKHAEFPLERELQAGDDAAKREADERRARLAGKGGPVGGSSGSGGGSGSGGWER
DVLEKVLMASLREQRSARRWKIFFRFLTLAIVALILYAVIDFKGDVLSSTSGRHTAMVTLDGEIAAGTTASADSINAALQ
AAFEDTSAAGVILKINSPGGSPVQAGIINDEIHRLRKLYPDKPFYVVVEEICASGGYYVAAAADKIYVDKASIVGSIGVL
MDGFGFTGLMDKVGVQRRLYTSGANKGMLDPFSPEVPRQKGYAESMLKEIHQQFIDVVKEGRGDRLKNDPELFSGLFWSG
ERAVELGLADGLGSADYVARDLFKAEDIVDYTVKENIAERMAKRFGAAAGSAAMKLMMMSATVPSVR

Sequences:

>Translated_387_residues
MTEQQNPPNEPGQPQERAGDDSKLETAKHAEFPLERELQAGDDAAKREADERRARLAGKGGPVGGSSGSGGGSGSGGWER
DVLEKVLMASLREQRSARRWKIFFRFLTLAIVALILYAVIDFKGDVLSSTSGRHTAMVTLDGEIAAGTTASADSINAALQ
AAFEDTSAAGVILKINSPGGSPVQAGIINDEIHRLRKLYPDKPFYVVVEEICASGGYYVAAAADKIYVDKASIVGSIGVL
MDGFGFTGLMDKVGVQRRLYTSGANKGMLDPFSPEVPRQKGYAESMLKEIHQQFIDVVKEGRGDRLKNDPELFSGLFWSG
ERAVELGLADGLGSADYVARDLFKAEDIVDYTVKENIAERMAKRFGAAAGSAAMKLMMMSATVPSVR
>Mature_386_residues
TEQQNPPNEPGQPQERAGDDSKLETAKHAEFPLERELQAGDDAAKREADERRARLAGKGGPVGGSSGSGGGSGSGGWERD
VLEKVLMASLREQRSARRWKIFFRFLTLAIVALILYAVIDFKGDVLSSTSGRHTAMVTLDGEIAAGTTASADSINAALQA
AFEDTSAAGVILKINSPGGSPVQAGIINDEIHRLRKLYPDKPFYVVVEEICASGGYYVAAAADKIYVDKASIVGSIGVLM
DGFGFTGLMDKVGVQRRLYTSGANKGMLDPFSPEVPRQKGYAESMLKEIHQQFIDVVKEGRGDRLKNDPELFSGLFWSGE
RAVELGLADGLGSADYVARDLFKAEDIVDYTVKENIAERMAKRFGAAAGSAAMKLMMMSATVPSVR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=255, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788064, Length=200, Percent_Identity=27, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41520; Mature: 41389

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQQNPPNEPGQPQERAGDDSKLETAKHAEFPLERELQAGDDAAKREADERRARLAGKG
CCCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCC
GPVGGSSGSGGGSGSGGWERDVLEKVLMASLREQRSARRWKIFFRFLTLAIVALILYAVI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFKGDVLSSTSGRHTAMVTLDGEIAAGTTASADSINAALQAAFEDTSAAGVILKINSPGG
HCCCCHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCC
SPVQAGIINDEIHRLRKLYPDKPFYVVVEEICASGGYYVAAAADKIYVDKASIVGSIGVL
CCEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCEEEEEHHHHHHHHHHH
MDGFGFTGLMDKVGVQRRLYTSGANKGMLDPFSPEVPRQKGYAESMLKEIHQQFIDVVKE
HCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GRGDRLKNDPELFSGLFWSGERAVELGLADGLGSADYVARDLFKAEDIVDYTVKENIAER
CCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MAKRFGAAAGSAAMKLMMMSATVPSVR
HHHHHCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEQQNPPNEPGQPQERAGDDSKLETAKHAEFPLERELQAGDDAAKREADERRARLAGKG
CCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCC
GPVGGSSGSGGGSGSGGWERDVLEKVLMASLREQRSARRWKIFFRFLTLAIVALILYAVI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFKGDVLSSTSGRHTAMVTLDGEIAAGTTASADSINAALQAAFEDTSAAGVILKINSPGG
HCCCCHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCC
SPVQAGIINDEIHRLRKLYPDKPFYVVVEEICASGGYYVAAAADKIYVDKASIVGSIGVL
CCEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCEEEEEHHHHHHHHHHH
MDGFGFTGLMDKVGVQRRLYTSGANKGMLDPFSPEVPRQKGYAESMLKEIHQQFIDVVKE
HCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GRGDRLKNDPELFSGLFWSGERAVELGLADGLGSADYVARDLFKAEDIVDYTVKENIAER
CCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MAKRFGAAAGSAAMKLMMMSATVPSVR
HHHHHCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA