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The map label for this gene is fabD [H]

Identifier: 94311365

GI number: 94311365

Start: 2638797

End: 2639732

Strand: Reverse

Name: fabD [H]

Synonym: Rmet_2429

Alternate gene names: 94311365

Gene position: 2639732-2638797 (Counterclockwise)

Preceding gene: 335055598

Following gene: 94311364

Centisome position: 67.2

GC content: 65.71

Gene sequence:

>936_bases
ATGAAATTCGCATTTGTTTTCCCCGGACAGGGTTCGCAGTCGGTCGGCATGCTCAATGCCTTTGCCGATAACCCAGTGGT
GCGTGCCACGCTTGAAGAAGCTTCGACGGCGCTGGGTCAGGACATCGGCAAGCTGATTGCGGAAGGTCCGGCCGAAGAGC
TGAACCTGACGACCAACACGCAGCCCGTGATGCTGACGGCCGCAGTGGCCGTGTACCGCGCATGGCTCGACGCCGGTGGT
CCGGCTCCGGCGCTGGTTGCAGGCCATAGCCTGGGCGAGTACTCGGCGCTGGTGGCCGCAGGGGTGATCCCGTTTGCCGA
GGCGGTGCCGCTGGTTCGCTTCCGTGCCCAGGCGATGCAGGAAGCGGTGCCGGTGGGTGAGGGCGGCATGGCCGCGATCC
TTGGCCTGTCGGACGATGACGTGCGCGCCGCGTGCGCCGAGGCTGCGGCGGCAGGCGCTGGCGTGGTCGAGGCTGTCAAC
TTCAATGCCCCGTCGCAGGTGGTGATCGCCGGCAACAAGGGCGCCGTGGAAAAGGCCTGCGAGATTGCCAAGGCGAAGGG
CGCCAAGCGCGCGCTGCCGCTGCCGGTGTCCGCCCCGTTCCACTCGTCGCTGCTCAAGCCTGCCTCCGATCGCCTGCGCG
AGCGCATGGCTGGCCTGTCGTTCTCGGCACCGGCCATTCCGCTGGTGAACAATGTCGACGTGGCAATCATCAGTGACCCG
GCTCAGATCAAGGACGCGCTTGTTCGTCAGGCAGCCGCTCCGGTACGCTGGGTCGAGTGCGTGCAGAAGATTGCCGCCGA
GGGCGTGACACACGTGATCGAGTGCGGTCCGGGTAAAGTGCTGGCCGGTATGACCAAGCGCATCGACGGCAACCTCGTTG
GTGGTGCAATCTTTGATCCGGCGTCGCTGCAGGAAACGCTGGCGCTGCTGAAGTAA

Upstream 100 bases:

>100_bases
TGGGGCGCGGTGCTGCTGCGCATGTAAGATGCGGCCGGCGCGCGGCGCGTAGAACGCGGTGCACCAGTTGACAAGATGAA
TTGCTAGGACTGGATTTCAG

Downstream 100 bases:

>100_bases
GACCAAGGAACAAACGCAACATGAGCAAGACTCTGGAGAATCAGGTCGCACTGGTGACCGGCGCATCGCGCGGGATCGGC
CGTGCCATCGCGCTGGAGCT

Product: malonyl-CoA-(acyl-carrier-protein) transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKFAFVFPGQGSQSVGMLNAFADNPVVRATLEEASTALGQDIGKLIAEGPAEELNLTTNTQPVMLTAAVAVYRAWLDAGG
PAPALVAGHSLGEYSALVAAGVIPFAEAVPLVRFRAQAMQEAVPVGEGGMAAILGLSDDDVRAACAEAAAAGAGVVEAVN
FNAPSQVVIAGNKGAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDRLRERMAGLSFSAPAIPLVNNVDVAIISDP
AQIKDALVRQAAAPVRWVECVQKIAAEGVTHVIECGPGKVLAGMTKRIDGNLVGGAIFDPASLQETLALLK

Sequences:

>Translated_311_residues
MKFAFVFPGQGSQSVGMLNAFADNPVVRATLEEASTALGQDIGKLIAEGPAEELNLTTNTQPVMLTAAVAVYRAWLDAGG
PAPALVAGHSLGEYSALVAAGVIPFAEAVPLVRFRAQAMQEAVPVGEGGMAAILGLSDDDVRAACAEAAAAGAGVVEAVN
FNAPSQVVIAGNKGAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDRLRERMAGLSFSAPAIPLVNNVDVAIISDP
AQIKDALVRQAAAPVRWVECVQKIAAEGVTHVIECGPGKVLAGMTKRIDGNLVGGAIFDPASLQETLALLK
>Mature_311_residues
MKFAFVFPGQGSQSVGMLNAFADNPVVRATLEEASTALGQDIGKLIAEGPAEELNLTTNTQPVMLTAAVAVYRAWLDAGG
PAPALVAGHSLGEYSALVAAGVIPFAEAVPLVRFRAQAMQEAVPVGEGGMAAILGLSDDDVRAACAEAAAAGAGVVEAVN
FNAPSQVVIAGNKGAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDRLRERMAGLSFSAPAIPLVNNVDVAIISDP
AQIKDALVRQAAAPVRWVECVQKIAAEGVTHVIECGPGKVLAGMTKRIDGNLVGGAIFDPASLQETLALLK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=31.2292358803987, Blast_Score=142, Evalue=3e-34,
Organism=Escherichia coli, GI1787334, Length=309, Percent_Identity=57.2815533980583, Blast_Score=322, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=29.553264604811, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=300, Percent_Identity=30.6666666666667, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI212642053, Length=294, Percent_Identity=27.2108843537415, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665753, Length=300, Percent_Identity=32, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31772; Mature: 31772

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00889 CNMP_BINDING_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADNPVVRATLEEASTALGQDIGKLIAEGPAEELNLTTNT
CEEEEEECCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHCEECCCC
QPVMLTAAVAVYRAWLDAGGPAPALVAGHSLGEYSALVAAGVIPFAEAVPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVPVGEGGMAAILGLSDDDVRAACAEAAAAGAGVVEAVNFNAPSQVVIAGNKGAVEKAC
HHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCHHHHHH
EIAKAKGAKRALPLPVSAPFHSSLLKPASDRLRERMAGLSFSAPAIPLVNNVDVAIISDP
HHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCEECCCCEEEECCH
AQIKDALVRQAAAPVRWVECVQKIAAEGVTHVIECGPGKVLAGMTKRIDGNLVGGAIFDP
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCEECCCCCCH
ASLQETLALLK
HHHHHHHHHCC
>Mature Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADNPVVRATLEEASTALGQDIGKLIAEGPAEELNLTTNT
CEEEEEECCCCCCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHCEECCCC
QPVMLTAAVAVYRAWLDAGGPAPALVAGHSLGEYSALVAAGVIPFAEAVPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVPVGEGGMAAILGLSDDDVRAACAEAAAAGAGVVEAVNFNAPSQVVIAGNKGAVEKAC
HHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCHHHHHH
EIAKAKGAKRALPLPVSAPFHSSLLKPASDRLRERMAGLSFSAPAIPLVNNVDVAIISDP
HHHHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCCCCEECCCCEEEECCH
AQIKDALVRQAAAPVRWVECVQKIAAEGVTHVIECGPGKVLAGMTKRIDGNLVGGAIFDP
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCEECCCCCCH
ASLQETLALLK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]