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The map label for this gene is ccmF [H]

Identifier: 94311326

GI number: 94311326

Start: 2600281

End: 2602242

Strand: Direct

Name: ccmF [H]

Synonym: Rmet_2390

Alternate gene names: 94311326

Gene position: 2600281-2602242 (Clockwise)

Preceding gene: 94311325

Following gene: 94311327

Centisome position: 66.2

GC content: 62.28

Gene sequence:

>1962_bases
ATGATTCCAGAAATCGGCCACCTCGCCCTCATCGCTGCCTTGTTCGTGGCACTCGCTCAAGGTGTTCTTGCCCTGGCCGG
CGCGGCGCGAGCCAACCTCACCTGGATCGCGTTCGCCCGCCCCGCTGCACGCGCTCAATTCCTGTTGGTGATGGTCGGTT
TTGCCGCGCTCACCTGGGCCTTTGTCGCGAAGGACTACTCGGTCGCCTACGTCGCTCAAAACTCCAATTCTCAGCTCCCG
CTGGGCTACAGAATGGCCGCGGTCTGGGGCGGACATGAGGGTTCGCTCCTGCTCTGGCTGCTGATGCAGACCGGCTGGGC
CTATGCGGTCAGCCGGTTGTCGAAACAGCTTCCGGATGCCATGGTGGCGCGCGTTCTGGGCGTGCTCGGCCTGGTGACGG
CCGGCTTCCTGCTGTTCGTCCTGTTGACCTCCAATCCCTTCGAGCGACTTTTCCCGGTACCGCAAGATGGATGGGATCTG
AATCCGCTCCTGCAGGATATCGGCTTGATCTTTCATCCACCGCTGCTTTACATGGGGTACGTCGGATTTTCGGTGGCCTT
CGCATTCGCGATTGCTGCATTGCTTGCCGGACAACTGGACTCGACGTGGGCACGCTGGTCTCGTCCCTGGGCCACCGCAG
CCTGGGCAAATCTGACGGTCGGAATCGCCTTGGGGAGTTGGTGGGCCTACTACGAGTTGGGCTGGGGGGGCTGGTGGTTT
TGGGACCCGGTCGAGAACTCGTCGTTCATCCCCTGGCTGGTGGGCACCGCCTTGATCCACTCTTTGGCGGTGACGGAAAA
GCGGGCCAGTTTCAAGAACTGGACGGTGCTGCTCTCGATCGGCGCATTTTCTTGCTCGCTTTTGGGTGCCTTTCTGGTGC
GCTCGGGCGTACTGACTTCTGTGCATGCATTTGCCACCGATCCGCGACGCGGGTTATTCATTCTGATTCTGCTGACGGTC
ATTGTGGGCACGTCGCTCGCTTTGTTCGCATGGCGAGCCCCTAAGGTCGGCATGGGAGGACGGTTCGACATGGTCTCCAG
GGAGTCCTTGCTGCTGGTCAACAATGTGCTGTTGGTCGTCACTGCCGGCGCTGTCGCGCTCGGTACGCTGTACCCACTGC
TCGTCGATGCGCTGGGCCTGGGCAAGCTCTCCGTGGGGCCGCCATACTTCAATGCGGTGTTCGTGCCATTGATGATCCCC
GCGTTGCTTCTGATTGCGGTAGGACCCGCCGCCAATTGGAAGGCCGCCCAGTTCGGTGCCATCTTCAGGCAGTTGCGCGT
GCCGATGATTGCTGCACCCCTGGTGGGCCTGACCGCCCCGTTCGTGCTGGGGCACTGGTCAGCTTCTGCGGCGTTGGGCT
TGATGCTCGCCACGTGGATTGCGGTGTCGGTGGTGACGGGCATCTTCGGCCGAATGCGCGCCACCCGCGGCGGGTTGCGT
GCCCAGCCACGCAGTTGGCTTGGGATGCATATGGCGCATCTGGGCATCGCGGTATTCGTGACTGGCGTGACCATCGTCAG
TGGGTATGAGACCGAGCGAGACGTTCGATTGGCCCAGGGCGAGTCCGTCAGCATCGGCGGCTACGACCTCACTTTGATCG
GCGTCAGAAGCACGCGGGGGCCCAACTACGTGGCGCAGATAGGCGATATCGAACTGTCGCGCGACGGCAAGGTCTTGCGT
CGGCTGCATCCGGAAAAGCGCAATTACCCGGCCTCGCAGATGCCGATGACCGAGGTGGCGATCGATGCAAACGGACTGCG
CCACGTCTACGCGGCGCTCGGCGAACCGCTCGGCGACGGTGTTTGGAGCGTTCGTGTCTACCACAAGCCATTCGTTGACT
GGATCTGGATCGGCTGCATCCTGATGGCGCTTGGCGGTGGCTTGGCCATCAGCGATCGTCGATACCGTCTGAAGCCTCGC
CGTCAACACGTCGCTCCGCCATTGCCCGAGGCCGCATCATGA

Upstream 100 bases:

>100_bases
GGAGGTGCTGGCCAAGCACGACGAGAACTACATGCCGCCCGAGGCCCAGCATGCGCTGGACGAAGTCCAGAAGAAGCCGG
CTTCAAGGAAGCCTTGACCC

Downstream 100 bases:

>100_bases
ACCGTTTCCTATGGCCGCTGCTCGGATTCCTTGTCTTGGTGTCGTTCCTCGCAGTGGGCCTGACGCTCAAGCCCAGCGAG
GTGCCATCGCCCTTGATCAA

Product: heme lyase, CcmF subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MIPEIGHLALIAALFVALAQGVLALAGAARANLTWIAFARPAARAQFLLVMVGFAALTWAFVAKDYSVAYVAQNSNSQLP
LGYRMAAVWGGHEGSLLLWLLMQTGWAYAVSRLSKQLPDAMVARVLGVLGLVTAGFLLFVLLTSNPFERLFPVPQDGWDL
NPLLQDIGLIFHPPLLYMGYVGFSVAFAFAIAALLAGQLDSTWARWSRPWATAAWANLTVGIALGSWWAYYELGWGGWWF
WDPVENSSFIPWLVGTALIHSLAVTEKRASFKNWTVLLSIGAFSCSLLGAFLVRSGVLTSVHAFATDPRRGLFILILLTV
IVGTSLALFAWRAPKVGMGGRFDMVSRESLLLVNNVLLVVTAGAVALGTLYPLLVDALGLGKLSVGPPYFNAVFVPLMIP
ALLLIAVGPAANWKAAQFGAIFRQLRVPMIAAPLVGLTAPFVLGHWSASAALGLMLATWIAVSVVTGIFGRMRATRGGLR
AQPRSWLGMHMAHLGIAVFVTGVTIVSGYETERDVRLAQGESVSIGGYDLTLIGVRSTRGPNYVAQIGDIELSRDGKVLR
RLHPEKRNYPASQMPMTEVAIDANGLRHVYAALGEPLGDGVWSVRVYHKPFVDWIWIGCILMALGGGLAISDRRYRLKPR
RQHVAPPLPEAAS

Sequences:

>Translated_653_residues
MIPEIGHLALIAALFVALAQGVLALAGAARANLTWIAFARPAARAQFLLVMVGFAALTWAFVAKDYSVAYVAQNSNSQLP
LGYRMAAVWGGHEGSLLLWLLMQTGWAYAVSRLSKQLPDAMVARVLGVLGLVTAGFLLFVLLTSNPFERLFPVPQDGWDL
NPLLQDIGLIFHPPLLYMGYVGFSVAFAFAIAALLAGQLDSTWARWSRPWATAAWANLTVGIALGSWWAYYELGWGGWWF
WDPVENSSFIPWLVGTALIHSLAVTEKRASFKNWTVLLSIGAFSCSLLGAFLVRSGVLTSVHAFATDPRRGLFILILLTV
IVGTSLALFAWRAPKVGMGGRFDMVSRESLLLVNNVLLVVTAGAVALGTLYPLLVDALGLGKLSVGPPYFNAVFVPLMIP
ALLLIAVGPAANWKAAQFGAIFRQLRVPMIAAPLVGLTAPFVLGHWSASAALGLMLATWIAVSVVTGIFGRMRATRGGLR
AQPRSWLGMHMAHLGIAVFVTGVTIVSGYETERDVRLAQGESVSIGGYDLTLIGVRSTRGPNYVAQIGDIELSRDGKVLR
RLHPEKRNYPASQMPMTEVAIDANGLRHVYAALGEPLGDGVWSVRVYHKPFVDWIWIGCILMALGGGLAISDRRYRLKPR
RQHVAPPLPEAAS
>Mature_653_residues
MIPEIGHLALIAALFVALAQGVLALAGAARANLTWIAFARPAARAQFLLVMVGFAALTWAFVAKDYSVAYVAQNSNSQLP
LGYRMAAVWGGHEGSLLLWLLMQTGWAYAVSRLSKQLPDAMVARVLGVLGLVTAGFLLFVLLTSNPFERLFPVPQDGWDL
NPLLQDIGLIFHPPLLYMGYVGFSVAFAFAIAALLAGQLDSTWARWSRPWATAAWANLTVGIALGSWWAYYELGWGGWWF
WDPVENSSFIPWLVGTALIHSLAVTEKRASFKNWTVLLSIGAFSCSLLGAFLVRSGVLTSVHAFATDPRRGLFILILLTV
IVGTSLALFAWRAPKVGMGGRFDMVSRESLLLVNNVLLVVTAGAVALGTLYPLLVDALGLGKLSVGPPYFNAVFVPLMIP
ALLLIAVGPAANWKAAQFGAIFRQLRVPMIAAPLVGLTAPFVLGHWSASAALGLMLATWIAVSVVTGIFGRMRATRGGLR
AQPRSWLGMHMAHLGIAVFVTGVTIVSGYETERDVRLAQGESVSIGGYDLTLIGVRSTRGPNYVAQIGDIELSRDGKVLR
RLHPEKRNYPASQMPMTEVAIDANGLRHVYAALGEPLGDGVWSVRVYHKPFVDWIWIGCILMALGGGLAISDRRYRLKPR
RQHVAPPLPEAAS

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=648, Percent_Identity=53.7037037037037, Blast_Score=607, Evalue=1e-175,
Organism=Escherichia coli, GI1790511, Length=379, Percent_Identity=48.5488126649077, Blast_Score=297, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 70625; Mature: 70625

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPEIGHLALIAALFVALAQGVLALAGAARANLTWIAFARPAARAQFLLVMVGFAALTWA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
FVAKDYSVAYVAQNSNSQLPLGYRMAAVWGGHEGSLLLWLLMQTGWAYAVSRLSKQLPDA
HHHCCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHCHHH
MVARVLGVLGLVTAGFLLFVLLTSNPFERLFPVPQDGWDLNPLLQDIGLIFHPPLLYMGY
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHHHHCHHHHCCHHHHHHH
VGFSVAFAFAIAALLAGQLDSTWARWSRPWATAAWANLTVGIALGSWWAYYELGWGGWWF
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHEEEEEECCCEEEEEEECCCCEEE
WDPVENSSFIPWLVGTALIHSLAVTEKRASFKNWTVLLSIGAFSCSLLGAFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHH
VHAFATDPRRGLFILILLTVIVGTSLALFAWRAPKVGMGGRFDMVSRESLLLVNNVLLVV
HHHHCCCCCCCHHHHHHHHHHHHCHHHHHEECCCCCCCCCCCCCCCCCCHHHHHCCHHEE
TAGAVALGTLYPLLVDALGLGKLSVGPPYFNAVFVPLMIPALLLIAVGPAANWKAAQFGA
EHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IFRQLRVPMIAAPLVGLTAPFVLGHWSASAALGLMLATWIAVSVVTGIFGRMRATRGGLR
HHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AQPRSWLGMHMAHLGIAVFVTGVTIVSGYETERDVRLAQGESVSIGGYDLTLIGVRSTRG
CCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEECCCEEEECCEEEEEEEEECCCC
PNYVAQIGDIELSRDGKVLRRLHPEKRNYPASQMPMTEVAIDANGLRHVYAALGEPLGDG
CCCEEEECCEEECCCCHHHHHCCCHHCCCCCCCCCCHHEEECCCHHHHHHHHHCCCCCCC
VWSVRVYHKPFVDWIWIGCILMALGGGLAISDRRYRLKPRRQHVAPPLPEAAS
EEEEEEECCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MIPEIGHLALIAALFVALAQGVLALAGAARANLTWIAFARPAARAQFLLVMVGFAALTWA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
FVAKDYSVAYVAQNSNSQLPLGYRMAAVWGGHEGSLLLWLLMQTGWAYAVSRLSKQLPDA
HHHCCCEEEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHCHHH
MVARVLGVLGLVTAGFLLFVLLTSNPFERLFPVPQDGWDLNPLLQDIGLIFHPPLLYMGY
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCHHHHHCHHHHCCHHHHHHH
VGFSVAFAFAIAALLAGQLDSTWARWSRPWATAAWANLTVGIALGSWWAYYELGWGGWWF
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHEEEEEECCCEEEEEEECCCCEEE
WDPVENSSFIPWLVGTALIHSLAVTEKRASFKNWTVLLSIGAFSCSLLGAFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHH
VHAFATDPRRGLFILILLTVIVGTSLALFAWRAPKVGMGGRFDMVSRESLLLVNNVLLVV
HHHHCCCCCCCHHHHHHHHHHHHCHHHHHEECCCCCCCCCCCCCCCCCCHHHHHCCHHEE
TAGAVALGTLYPLLVDALGLGKLSVGPPYFNAVFVPLMIPALLLIAVGPAANWKAAQFGA
EHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IFRQLRVPMIAAPLVGLTAPFVLGHWSASAALGLMLATWIAVSVVTGIFGRMRATRGGLR
HHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AQPRSWLGMHMAHLGIAVFVTGVTIVSGYETERDVRLAQGESVSIGGYDLTLIGVRSTRG
CCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEECCCEEEECCEEEEEEEEECCCC
PNYVAQIGDIELSRDGKVLRRLHPEKRNYPASQMPMTEVAIDANGLRHVYAALGEPLGDG
CCCEEEECCEEECCCCHHHHHCCCHHCCCCCCCCCCHHEEECCCHHHHHHHHHCCCCCCC
VWSVRVYHKPFVDWIWIGCILMALGGGLAISDRRYRLKPRRQHVAPPLPEAAS
EEEEEEECCHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]