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The map label for this gene is pbrC2 [H]

Identifier: 94311242

GI number: 94311242

Start: 2526140

End: 2526640

Strand: Direct

Name: pbrC2 [H]

Synonym: Rmet_2304

Alternate gene names: 94311242

Gene position: 2526140-2526640 (Clockwise)

Preceding gene: 94311241

Following gene: 94311243

Centisome position: 64.31

GC content: 61.48

Gene sequence:

>501_bases
ATGGATGAACCATCTCTTCGCAAGACGCAGTGGTACTCACTCGCGATCGTTATATTCGCCGGCGATCAGGCAGCTAAGAG
CTACATTGACGCGACAACTCCCTTGGGTTGGTCGCACGAGGTGGCGTCATTCTTCAACCTAGTTCACGCTCTCAATCCCG
GCGCGGCGTTCAGCTTCCTTGCTGGCGCGGGCGGCTGGCAGCGGTGGTTTTTTCTGGCGATCGCGTTCGCAATATCGGCA
TGGCTCGCATGGCTGCTCTCCCGGCCGCTGCGCAAAACGGAAGGCCTTTCGTACAGCCTCATTCTGGGCGGCGCATTGGG
CAACGCGTTCGACCGCGCCACGCGCGGGCACGTTATCGACTACATCGACTTTCACCTGCACGGCTGGCACTGGCCCGCCT
TCAACATCGCTGACATGGCCATCGTGGGCGGGGCGATCGCGCTGGTGGCCCAGTCGTTCATGAGCGTGGAGAACCCGGCC
GCCACAAAGGAGTCCCAGTGA

Upstream 100 bases:

>100_bases
GCATGCCACCATGTGGATGGCTGTGTTCGCTGACATGGGGGCAAGTCTTTTGGTTGTCGTCAATGGGCTGCGCCTCCTGA
AGTTCAAGGCGGCATGAACA

Downstream 100 bases:

>100_bases
CATTGGGACGATCCGGAAATTCGCAATGCACACGGTGCAGGACACCAATCTGAAGAGAACGGCCCCCAGCATGAGCGGCC
GCGGCTTGGCCCTCATGCTA

Product: prolipoprotein signal peptidase (signal peptidase II)

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MDEPSLRKTQWYSLAIVIFAGDQAAKSYIDATTPLGWSHEVASFFNLVHALNPGAAFSFLAGAGGWQRWFFLAIAFAISA
WLAWLLSRPLRKTEGLSYSLILGGALGNAFDRATRGHVIDYIDFHLHGWHWPAFNIADMAIVGGAIALVAQSFMSVENPA
ATKESQ

Sequences:

>Translated_166_residues
MDEPSLRKTQWYSLAIVIFAGDQAAKSYIDATTPLGWSHEVASFFNLVHALNPGAAFSFLAGAGGWQRWFFLAIAFAISA
WLAWLLSRPLRKTEGLSYSLILGGALGNAFDRATRGHVIDYIDFHLHGWHWPAFNIADMAIVGGAIALVAQSFMSVENPA
ATKESQ
>Mature_166_residues
MDEPSLRKTQWYSLAIVIFAGDQAAKSYIDATTPLGWSHEVASFFNLVHALNPGAAFSFLAGAGGWQRWFFLAIAFAISA
WLAWLLSRPLRKTEGLSYSLILGGALGNAFDRATRGHVIDYIDFHLHGWHWPAFNIADMAIVGGAIALVAQSFMSVENPA
ATKESQ

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=158, Percent_Identity=43.0379746835443, Blast_Score=117, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18157; Mature: 18157

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEPSLRKTQWYSLAIVIFAGDQAAKSYIDATTPLGWSHEVASFFNLVHALNPGAAFSFL
CCCCCCCCEEEEEEEEEEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
AGAGGWQRWFFLAIAFAISAWLAWLLSRPLRKTEGLSYSLILGGALGNAFDRATRGHVID
HCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCEEEEEECCHHHHHHHHHHCCCEEE
YIDFHLHGWHWPAFNIADMAIVGGAIALVAQSFMSVENPAATKESQ
EEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDEPSLRKTQWYSLAIVIFAGDQAAKSYIDATTPLGWSHEVASFFNLVHALNPGAAFSFL
CCCCCCCCEEEEEEEEEEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
AGAGGWQRWFFLAIAFAISAWLAWLLSRPLRKTEGLSYSLILGGALGNAFDRATRGHVID
HCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCEEEEEECCHHHHHHHHHHCCCEEE
YIDFHLHGWHWPAFNIADMAIVGGAIALVAQSFMSVENPAATKESQ
EEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA