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The map label for this gene is glpD [H]

Identifier: 94311177

GI number: 94311177

Start: 2454839

End: 2456479

Strand: Direct

Name: glpD [H]

Synonym: Rmet_2239

Alternate gene names: 94311177

Gene position: 2454839-2456479 (Clockwise)

Preceding gene: 94311176

Following gene: 94311178

Centisome position: 62.49

GC content: 68.62

Gene sequence:

>1641_bases
ATGACGCCGCACGCTGAACCCAGATTCGAATTTCCCATGCAAACTTCCGTCACTCCGATCGCCCCTCCCTCCCGCGACAC
CCTGCTTCAGACGCTCGCGCGCGAGCCACGCTGGGATGTGATCGTCATCGGCGGCGGCGCCACCGGGCTGGGCACCGCGC
TCGACGCTGCTTCGCGTGGCTACCGCACGCTGCTGCTCGAAGCCGCCGACTTCGCCAAGGGCACGTCGAGCAAGGCCACC
AAGCTCGTGCACGGCGGCGTTCGCTACCTGGCGCAAGGCAACATCAGCCTGGTGCGCGAGGCCCTGCACGAACGCGGCCT
GCTCGCGCGCAACGCACCGCACGTGGTGTGGCCGCTTGGCTTCGTCGTGCCGGCCTACCAGATGTTCGACCAGCCGTTCT
ACGGGATCGGCCTGAAGCTCTATGACATGCTGGCAGGCGGCCTGAACCTTTCCGGCAGCCGCTGGCTCAGCCATCACGAA
ACGCTCGAGGCCGCGCCAACCCTGGCCGAGCACGTGGGCGGGCGTCCGCTGCGCGGTGGCAATCTGTATTTCGACGGCCA
GTTCGATGACGCGCGGCTGGCGATGGCGTTGATGCGCACGCTGTTCGATGTGGGCGGCACCGCGGTCAACTACATGCGCG
TGAGCGGACTCTCGCAGTCCAACGGCGTCATCACCGGCGTCACGGCACAAGATGTGATCGGTGGGGAGACGTTCCACCTG
CGCGCGGATTGCGTGATCAACGCCACCGGCGTGTGGGTCGATGCCGTGCGCCAGATGGAAGACGGCCAGGCCCGGCGGAT
GGTGGCGCCGAGCCAGGGCGTTCACTTGACGATTCCGCGCAGCTTCCTGCCCGGCGATCGCGCAGTCCTGATTCCGAAAA
CCGACGATGGCCGCGTGCTGTTCCTGGTGCCCTGGAACGGACACACGATCGTCGGCACCACCGACACCCCGCGCCAGGAT
CTACCGCTGGAGCCCCGGGCAGCGAGCGACGACGTCGACTTCATCCTGGAAACGGCCGCGCGTTACCTGGCCCGCGACCC
GACCCGCGATGACGTGACCAGCGTCTGGGCGGGGCTGCGTCCGCTGGTGAAGGCCACCGGAGAAGCCTCCACCGCGTCGT
TGTCGCGCGAGCATACGATCCTGGTATCCAAAGCCGGACTGATCACGGTCACGGGCGGCAAATGGACCACGTATCGCAAG
ATGGCCGAGGACGTGATGGAAACCGCGATCCAGCGGCAGTTGCTGCGCGCCGCGCCCTGCCGCACGGCCGACCTGCCGCT
GCACGGCGCGACCAACATGCCCAATGACCTGCCGCCCTCGGGCACCGGATCGCCCGACCGCTACTACGGCGCCGACCTCC
CCCTGGTTCAGGCGATGCCTGGCGCGGACAACGTGCTCGTGCCCGCCTCCGGCCTGACCGAGGCCCACGTCCGCTTTGCG
GCGCGCTACGAGCTGGCCCGCCGCGTTGAGGACGTGCTGGCGCGGCGCAATCGGGCGCTGTTCCTGGACGCCCGCGCTGC
GCTGGACGGCGCCCCCCGGGTGGCGGCGATCCTGGCGGAGGAACTCGCGCACGACTCGGCCTGGCAGGCACGCGAACTCG
AGGACTTCGGCAAGCTCGCCAGGGGCTATATGCTCGGATGA

Upstream 100 bases:

>100_bases
CAGCGCTTCGAGCCGAAGCTGTCCGCCGACGAACGCGAACGCCGCATTGCGCGTTGGCACCGCGCCGTCGACCGCGCCCG
CGACTGGGCGCGCGAGTCCG

Downstream 100 bases:

>100_bases
TCGACGATACCTGCGTTCATGGTGCTGGACTTGGGCGATAATGCCGGTTAACGCATCAGGGAGAACACCATGGACGATAT
GGACGAGATTGACGATCTGT

Product: sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MTPHAEPRFEFPMQTSVTPIAPPSRDTLLQTLAREPRWDVIVIGGGATGLGTALDAASRGYRTLLLEAADFAKGTSSKAT
KLVHGGVRYLAQGNISLVREALHERGLLARNAPHVVWPLGFVVPAYQMFDQPFYGIGLKLYDMLAGGLNLSGSRWLSHHE
TLEAAPTLAEHVGGRPLRGGNLYFDGQFDDARLAMALMRTLFDVGGTAVNYMRVSGLSQSNGVITGVTAQDVIGGETFHL
RADCVINATGVWVDAVRQMEDGQARRMVAPSQGVHLTIPRSFLPGDRAVLIPKTDDGRVLFLVPWNGHTIVGTTDTPRQD
LPLEPRAASDDVDFILETAARYLARDPTRDDVTSVWAGLRPLVKATGEASTASLSREHTILVSKAGLITVTGGKWTTYRK
MAEDVMETAIQRQLLRAAPCRTADLPLHGATNMPNDLPPSGTGSPDRYYGADLPLVQAMPGADNVLVPASGLTEAHVRFA
ARYELARRVEDVLARRNRALFLDARAALDGAPRVAAILAEELAHDSAWQARELEDFGKLARGYMLG

Sequences:

>Translated_546_residues
MTPHAEPRFEFPMQTSVTPIAPPSRDTLLQTLAREPRWDVIVIGGGATGLGTALDAASRGYRTLLLEAADFAKGTSSKAT
KLVHGGVRYLAQGNISLVREALHERGLLARNAPHVVWPLGFVVPAYQMFDQPFYGIGLKLYDMLAGGLNLSGSRWLSHHE
TLEAAPTLAEHVGGRPLRGGNLYFDGQFDDARLAMALMRTLFDVGGTAVNYMRVSGLSQSNGVITGVTAQDVIGGETFHL
RADCVINATGVWVDAVRQMEDGQARRMVAPSQGVHLTIPRSFLPGDRAVLIPKTDDGRVLFLVPWNGHTIVGTTDTPRQD
LPLEPRAASDDVDFILETAARYLARDPTRDDVTSVWAGLRPLVKATGEASTASLSREHTILVSKAGLITVTGGKWTTYRK
MAEDVMETAIQRQLLRAAPCRTADLPLHGATNMPNDLPPSGTGSPDRYYGADLPLVQAMPGADNVLVPASGLTEAHVRFA
ARYELARRVEDVLARRNRALFLDARAALDGAPRVAAILAEELAHDSAWQARELEDFGKLARGYMLG
>Mature_545_residues
TPHAEPRFEFPMQTSVTPIAPPSRDTLLQTLAREPRWDVIVIGGGATGLGTALDAASRGYRTLLLEAADFAKGTSSKATK
LVHGGVRYLAQGNISLVREALHERGLLARNAPHVVWPLGFVVPAYQMFDQPFYGIGLKLYDMLAGGLNLSGSRWLSHHET
LEAAPTLAEHVGGRPLRGGNLYFDGQFDDARLAMALMRTLFDVGGTAVNYMRVSGLSQSNGVITGVTAQDVIGGETFHLR
ADCVINATGVWVDAVRQMEDGQARRMVAPSQGVHLTIPRSFLPGDRAVLIPKTDDGRVLFLVPWNGHTIVGTTDTPRQDL
PLEPRAASDDVDFILETAARYLARDPTRDDVTSVWAGLRPLVKATGEASTASLSREHTILVSKAGLITVTGGKWTTYRKM
AEDVMETAIQRQLLRAAPCRTADLPLHGATNMPNDLPPSGTGSPDRYYGADLPLVQAMPGADNVLVPASGLTEAHVRFAA
RYELARRVEDVLARRNRALFLDARAALDGAPRVAAILAEELAHDSAWQARELEDFGKLARGYMLG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=550, Percent_Identity=39.4545454545455, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI285002231, Length=550, Percent_Identity=39.4545454545455, Blast_Score=370, Evalue=1e-102,
Organism=Escherichia coli, GI2367226, Length=488, Percent_Identity=30.1229508196721, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1788574, Length=386, Percent_Identity=28.7564766839378, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17509253, Length=550, Percent_Identity=38.9090909090909, Blast_Score=330, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI115534726, Length=538, Percent_Identity=37.1747211895911, Blast_Score=325, Evalue=6e-89,
Organism=Saccharomyces cerevisiae, GI6322036, Length=613, Percent_Identity=34.584013050571, Blast_Score=303, Evalue=4e-83,
Organism=Drosophila melanogaster, GI161077125, Length=567, Percent_Identity=35.978835978836, Blast_Score=315, Evalue=6e-86,
Organism=Drosophila melanogaster, GI24653942, Length=567, Percent_Identity=35.978835978836, Blast_Score=315, Evalue=6e-86,
Organism=Drosophila melanogaster, GI24653944, Length=567, Percent_Identity=35.978835978836, Blast_Score=315, Evalue=6e-86,
Organism=Drosophila melanogaster, GI20130025, Length=567, Percent_Identity=35.978835978836, Blast_Score=315, Evalue=6e-86,
Organism=Drosophila melanogaster, GI24586295, Length=535, Percent_Identity=31.9626168224299, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI19921278, Length=545, Percent_Identity=33.0275229357798, Blast_Score=238, Evalue=6e-63,
Organism=Drosophila melanogaster, GI45550977, Length=384, Percent_Identity=32.2916666666667, Blast_Score=169, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 59060; Mature: 58929

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHAEPRFEFPMQTSVTPIAPPSRDTLLQTLAREPRWDVIVIGGGATGLGTALDAASRG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCC
YRTLLLEAADFAKGTSSKATKLVHGGVRYLAQGNISLVREALHERGLLARNAPHVVWPLG
CEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEHHH
FVVPAYQMFDQPFYGIGLKLYDMLAGGLNLSGSRWLSHHETLEAAPTLAEHVGGRPLRGG
HHHHHHHHHCCCCHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
NLYFDGQFDDARLAMALMRTLFDVGGTAVNYMRVSGLSQSNGVITGVTAQDVIGGETFHL
CEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCHHHHCCCCEEEE
RADCVINATGVWVDAVRQMEDGQARRMVAPSQGVHLTIPRSFLPGDRAVLIPKTDDGRVL
EEEEEEECCHHHHHHHHHHCCCCHHEEECCCCCEEEEECCCCCCCCCEEEEECCCCCEEE
FLVPWNGHTIVGTTDTPRQDLPLEPRAASDDVDFILETAARYLARDPTRDDVTSVWAGLR
EEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
PLVKATGEASTASLSREHTILVSKAGLITVTGGKWTTYRKMAEDVMETAIQRQLLRAAPC
HHHHHCCCCHHHHCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
RTADLPLHGATNMPNDLPPSGTGSPDRYYGADLPLVQAMPGADNVLVPASGLTEAHVRFA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEECCCCCCEEECCCCCCHHHHHHH
ARYELARRVEDVLARRNRALFLDARAALDGAPRVAAILAEELAHDSAWQARELEDFGKLA
HHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RGYMLG
HHCCCC
>Mature Secondary Structure 
TPHAEPRFEFPMQTSVTPIAPPSRDTLLQTLAREPRWDVIVIGGGATGLGTALDAASRG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCC
YRTLLLEAADFAKGTSSKATKLVHGGVRYLAQGNISLVREALHERGLLARNAPHVVWPLG
CEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEHHH
FVVPAYQMFDQPFYGIGLKLYDMLAGGLNLSGSRWLSHHETLEAAPTLAEHVGGRPLRGG
HHHHHHHHHCCCCHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
NLYFDGQFDDARLAMALMRTLFDVGGTAVNYMRVSGLSQSNGVITGVTAQDVIGGETFHL
CEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCHHHHCCCCEEEE
RADCVINATGVWVDAVRQMEDGQARRMVAPSQGVHLTIPRSFLPGDRAVLIPKTDDGRVL
EEEEEEECCHHHHHHHHHHCCCCHHEEECCCCCEEEEECCCCCCCCCEEEEECCCCCEEE
FLVPWNGHTIVGTTDTPRQDLPLEPRAASDDVDFILETAARYLARDPTRDDVTSVWAGLR
EEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
PLVKATGEASTASLSREHTILVSKAGLITVTGGKWTTYRKMAEDVMETAIQRQLLRAAPC
HHHHHCCCCHHHHCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
RTADLPLHGATNMPNDLPPSGTGSPDRYYGADLPLVQAMPGADNVLVPASGLTEAHVRFA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEECCCCCCEEECCCCCCHHHHHHH
ARYELARRVEDVLARRNRALFLDARAALDGAPRVAAILAEELAHDSAWQARELEDFGKLA
HHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RGYMLG
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]