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The map label for this gene is yegE [C]

Identifier: 94311165

GI number: 94311165

Start: 2440894

End: 2442882

Strand: Direct

Name: yegE [C]

Synonym: Rmet_2227

Alternate gene names: 94311165

Gene position: 2440894-2442882 (Clockwise)

Preceding gene: 94311164

Following gene: 335055586

Centisome position: 62.14

GC content: 64.86

Gene sequence:

>1989_bases
ATGCGGCACTCATTGAAGTACCGGATGGCGATCGCTGCCGCAATTGTGGTCACGCTGGTATTTGTGGCACGCGCGGGGAT
TTCCCAGTGGTACGCCTATGGGCGCCTGAACGACCTCGTTCAGAGCCAGCAGGACACACTGGTGAGGCTCGTCGCCAACC
AATTGGACGAGAAGCTCGAATCACGCGCAGTCGTGCTGCGACGGCTCGCCCGCAACCTGTCGCCCGTGCTCGACGCGCCC
TCCGCCCGACTGCGCCAGCTTGCCACCGACACCATCGACATACCGGAGCAATTCAACGCGGTCTTCATGGCATGGCCCGA
CGGCACACTCGCGTTCAGCACGGCGGTTCCGGATGGCGTCAAGATGATGATCAGCGACCGCGACTACTTCAAGGAAATCC
TGCGCGGCTCCCCGTTTGTCGTTTCGGACCTGCTGCAGGGCAAACACAGCGCCGCCCCCGGCGTCATCCTCGCCGTGCCC
CTGCGGGGAGCGAAGGGTGAACTGCGCGCAGTCGTCGGCGGCATCCTGAACCTGTCCGCGGACAACTTCCTGCGCGAACT
GGCCGGCAGCCGCATCGGCCTGACCGGGTTCTATTGCCTGGTCTCGGCCGGTCCGAATCCACGCTATGCCATGCATCCCG
ACAGCGCGAAGGTGCTCGCGCCTGCGCGCGCCTCGGGAGACTCCTGCGGCGCCGAACGGCCAGCTTCGCGCTGGGAAGCG
CTGGAGCCGCAGCAACCGGTCGTCGCGCGCCACCTGCTGGCATCAAACGGGTGGGAGGTGATATCGGTCCTGCCCGCCAA
GGAAGCCTACGGGCCGCTGCTCGAAGCCCGCCAACATGCCATCGTCATCGGCGTCGTTTCTCTGATCTTTGCGGCCGCGT
TGATGTGGATGACGATCCGTTTCCTGCTGGCCCCACTCGAACACCTGCATCGCGCCGTCAGGCAACTGGCCACGCGCCCA
TCCGCTGTGGCGGACCTGCTCGTCAACCGCGAGGACGAAATCGGCGAGCTTGCCGGCGCCTTCTGCGAGGTCATGCAGCA
ACTCTCCGAGCGCGAGGCAGCGCTCAAGGCCGCCAACGACAGCGCCGCGGCGAGCGAGAAACGCTTCGTGGCCATCGCCA
ATCATGTTCCCGAGTTCGTCGCTTTCATCGATGCCAGCGAGCGGTTCGCGTTCGTCAATCAGGCCTATGCGCGACACTAT
GGCCTGCCGGCCGACCAGATCACGGGCCTTTCTGTGCGAGAACTCTGGGGCACGCCAGACTACGTCGCCAACAAGCCCTA
CCTCGAGCGCGCGCGCACTGGCGAAGTCGTGACCTTCACGCGAGAAACCTCCGACGGCACCGCCCGGGAGATCACCTACC
AACCAGCGTGGAACGATACGCAGGACGTTCTCACCGGCCTGCACATGTTCGCCCGCGATGTGACCGGCGAACGCCTGAAG
CTGCGCACACTCGAAGCCCAGACGCTGTCCGATCACCTGACCGGCCTGCTGAATCGCAAGGGCTTCGACCGGCGACTGCA
GGAAGCCATGGCGCGAGCGGACTCGGCAGATCACGGTGCTGCGCTGCTGCTGGTGGATCTCGACGATTTCAAGGCGGTCA
ACGACAGCTACGGCCACCCGGTCGGCGACCGCCTGCTGGTCGCTTTCGCCGAACGGCTGCGCACCTGTGTACGCAGCGGC
GATGCTGTGGCCCGAATTGGCGGCGACGAGTTCGCCATCATCCTCGAACACATCACCACGCCGAGTATCGTCGAACGCAT
CGGACATGCTGTCGTTCATGCGGCGCTACGCCCGTTCACGATCGATGGCCAGACACTCGTCTCGACGTGCAGCGTCGGCA
GCGCGATCCACCAATCCGGCCAGAGCGCATCCGTCAGCGAACTGTTCATACGGGCGGATATGGCCCTGTACGACGCCAAG
CGACATGGCAAAGCCTGCTATTCGGCGACCGGCCCCAACAAGGCCACGGATATCGCTCCGCACGCGTAG

Upstream 100 bases:

>100_bases
GCTACGCTTTGAACCGGTTGCCGATGATAGATAGGTGGGGCCATTCAATGAAAGCATCCAGGCAGCCAAATACGGGTCAG
TGCGCGAATAGACAAGAATC

Downstream 100 bases:

>100_bases
CTGACGTGGCCCATTCGCAGCCCCGCCTCAGGCAACCGATAAGTCGTGCTCCGCCCCGGAAACGAGGGTCAGCTTTCTGC
CCGAGACGCGCCTGACCACG

Product: signal transduction protein (GGDEF domain)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MRHSLKYRMAIAAAIVVTLVFVARAGISQWYAYGRLNDLVQSQQDTLVRLVANQLDEKLESRAVVLRRLARNLSPVLDAP
SARLRQLATDTIDIPEQFNAVFMAWPDGTLAFSTAVPDGVKMMISDRDYFKEILRGSPFVVSDLLQGKHSAAPGVILAVP
LRGAKGELRAVVGGILNLSADNFLRELAGSRIGLTGFYCLVSAGPNPRYAMHPDSAKVLAPARASGDSCGAERPASRWEA
LEPQQPVVARHLLASNGWEVISVLPAKEAYGPLLEARQHAIVIGVVSLIFAAALMWMTIRFLLAPLEHLHRAVRQLATRP
SAVADLLVNREDEIGELAGAFCEVMQQLSEREAALKAANDSAAASEKRFVAIANHVPEFVAFIDASERFAFVNQAYARHY
GLPADQITGLSVRELWGTPDYVANKPYLERARTGEVVTFTRETSDGTAREITYQPAWNDTQDVLTGLHMFARDVTGERLK
LRTLEAQTLSDHLTGLLNRKGFDRRLQEAMARADSADHGAALLLVDLDDFKAVNDSYGHPVGDRLLVAFAERLRTCVRSG
DAVARIGGDEFAIILEHITTPSIVERIGHAVVHAALRPFTIDGQTLVSTCSVGSAIHQSGQSASVSELFIRADMALYDAK
RHGKACYSATGPNKATDIAPHA

Sequences:

>Translated_662_residues
MRHSLKYRMAIAAAIVVTLVFVARAGISQWYAYGRLNDLVQSQQDTLVRLVANQLDEKLESRAVVLRRLARNLSPVLDAP
SARLRQLATDTIDIPEQFNAVFMAWPDGTLAFSTAVPDGVKMMISDRDYFKEILRGSPFVVSDLLQGKHSAAPGVILAVP
LRGAKGELRAVVGGILNLSADNFLRELAGSRIGLTGFYCLVSAGPNPRYAMHPDSAKVLAPARASGDSCGAERPASRWEA
LEPQQPVVARHLLASNGWEVISVLPAKEAYGPLLEARQHAIVIGVVSLIFAAALMWMTIRFLLAPLEHLHRAVRQLATRP
SAVADLLVNREDEIGELAGAFCEVMQQLSEREAALKAANDSAAASEKRFVAIANHVPEFVAFIDASERFAFVNQAYARHY
GLPADQITGLSVRELWGTPDYVANKPYLERARTGEVVTFTRETSDGTAREITYQPAWNDTQDVLTGLHMFARDVTGERLK
LRTLEAQTLSDHLTGLLNRKGFDRRLQEAMARADSADHGAALLLVDLDDFKAVNDSYGHPVGDRLLVAFAERLRTCVRSG
DAVARIGGDEFAIILEHITTPSIVERIGHAVVHAALRPFTIDGQTLVSTCSVGSAIHQSGQSASVSELFIRADMALYDAK
RHGKACYSATGPNKATDIAPHA
>Mature_662_residues
MRHSLKYRMAIAAAIVVTLVFVARAGISQWYAYGRLNDLVQSQQDTLVRLVANQLDEKLESRAVVLRRLARNLSPVLDAP
SARLRQLATDTIDIPEQFNAVFMAWPDGTLAFSTAVPDGVKMMISDRDYFKEILRGSPFVVSDLLQGKHSAAPGVILAVP
LRGAKGELRAVVGGILNLSADNFLRELAGSRIGLTGFYCLVSAGPNPRYAMHPDSAKVLAPARASGDSCGAERPASRWEA
LEPQQPVVARHLLASNGWEVISVLPAKEAYGPLLEARQHAIVIGVVSLIFAAALMWMTIRFLLAPLEHLHRAVRQLATRP
SAVADLLVNREDEIGELAGAFCEVMQQLSEREAALKAANDSAAASEKRFVAIANHVPEFVAFIDASERFAFVNQAYARHY
GLPADQITGLSVRELWGTPDYVANKPYLERARTGEVVTFTRETSDGTAREITYQPAWNDTQDVLTGLHMFARDVTGERLK
LRTLEAQTLSDHLTGLLNRKGFDRRLQEAMARADSADHGAALLLVDLDDFKAVNDSYGHPVGDRLLVAFAERLRTCVRSG
DAVARIGGDEFAIILEHITTPSIVERIGHAVVHAALRPFTIDGQTLVSTCSVGSAIHQSGQSASVSELFIRADMALYDAK
RHGKACYSATGPNKATDIAPHA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=364, Percent_Identity=27.1978021978022, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI87081881, Length=215, Percent_Identity=33.953488372093, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1786584, Length=164, Percent_Identity=33.5365853658537, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787541, Length=181, Percent_Identity=35.3591160220994, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788956, Length=198, Percent_Identity=33.8383838383838, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI87081977, Length=173, Percent_Identity=31.2138728323699, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=34.3949044585987, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=32.5153374233129, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787262, Length=159, Percent_Identity=32.0754716981132, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787056, Length=181, Percent_Identity=32.5966850828729, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081974, Length=113, Percent_Identity=33.6283185840708, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082007, Length=188, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788085, Length=158, Percent_Identity=27.8481012658228, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787816, Length=187, Percent_Identity=28.8770053475936, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 72074; Mature: 72074

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHSLKYRMAIAAAIVVTLVFVARAGISQWYAYGRLNDLVQSQQDTLVRLVANQLDEKLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAVVLRRLARNLSPVLDAPSARLRQLATDTIDIPEQFNAVFMAWPDGTLAFSTAVPDGV
HHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCCCCHHCCEEEEECCCCCEEEECCCCCCC
KMMISDRDYFKEILRGSPFVVSDLLQGKHSAAPGVILAVPLRGAKGELRAVVGGILNLSA
EEEECCHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCH
DNFLRELAGSRIGLTGFYCLVSAGPNPRYAMHPDSAKVLAPARASGDSCGAERPASRWEA
HHHHHHHCCCCCCCEEEEEEEECCCCCCEEECCCCCCEEECCCCCCCCCCCCCCHHHHCC
LEPQQPVVARHLLASNGWEVISVLPAKEAYGPLLEARQHAIVIGVVSLIFAAALMWMTIR
CCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLAPLEHLHRAVRQLATRPSAVADLLVNREDEIGELAGAFCEVMQQLSEREAALKAAND
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SAAASEKRFVAIANHVPEFVAFIDASERFAFVNQAYARHYGLPADQITGLSVRELWGTPD
CHHHCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHCCCCC
YVANKPYLERARTGEVVTFTRETSDGTAREITYQPAWNDTQDVLTGLHMFARDVTGERLK
HHCCCCHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEE
LRTLEAQTLSDHLTGLLNRKGFDRRLQEAMARADSADHGAALLLVDLDDFKAVNDSYGHP
EEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHCCCCCCCC
VGDRLLVAFAERLRTCVRSGDAVARIGGDEFAIILEHITTPSIVERIGHAVVHAALRPFT
HHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEE
IDGQTLVSTCSVGSAIHQSGQSASVSELFIRADMALYDAKRHGKACYSATGPNKATDIAP
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCC
HA
CC
>Mature Secondary Structure
MRHSLKYRMAIAAAIVVTLVFVARAGISQWYAYGRLNDLVQSQQDTLVRLVANQLDEKLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAVVLRRLARNLSPVLDAPSARLRQLATDTIDIPEQFNAVFMAWPDGTLAFSTAVPDGV
HHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCCCCHHCCEEEEECCCCCEEEECCCCCCC
KMMISDRDYFKEILRGSPFVVSDLLQGKHSAAPGVILAVPLRGAKGELRAVVGGILNLSA
EEEECCHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCH
DNFLRELAGSRIGLTGFYCLVSAGPNPRYAMHPDSAKVLAPARASGDSCGAERPASRWEA
HHHHHHHCCCCCCCEEEEEEEECCCCCCEEECCCCCCEEECCCCCCCCCCCCCCHHHHCC
LEPQQPVVARHLLASNGWEVISVLPAKEAYGPLLEARQHAIVIGVVSLIFAAALMWMTIR
CCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLAPLEHLHRAVRQLATRPSAVADLLVNREDEIGELAGAFCEVMQQLSEREAALKAAND
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SAAASEKRFVAIANHVPEFVAFIDASERFAFVNQAYARHYGLPADQITGLSVRELWGTPD
CHHHCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHCCCCC
YVANKPYLERARTGEVVTFTRETSDGTAREITYQPAWNDTQDVLTGLHMFARDVTGERLK
HHCCCCHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEE
LRTLEAQTLSDHLTGLLNRKGFDRRLQEAMARADSADHGAALLLVDLDDFKAVNDSYGHP
EEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHCCCCCCCC
VGDRLLVAFAERLRTCVRSGDAVARIGGDEFAIILEHITTPSIVERIGHAVVHAALRPFT
HHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEE
IDGQTLVSTCSVGSAIHQSGQSASVSELFIRADMALYDAKRHGKACYSATGPNKATDIAP
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCC
HA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]