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The map label for this gene is ydbM [H]

Identifier: 94311155

GI number: 94311155

Start: 2430495

End: 2431703

Strand: Reverse

Name: ydbM [H]

Synonym: Rmet_2217

Alternate gene names: 94311155

Gene position: 2431703-2430495 (Counterclockwise)

Preceding gene: 94311162

Following gene: 94311154

Centisome position: 61.91

GC content: 69.07

Gene sequence:

>1209_bases
ATGTCTTCGTCCCCCTTGCGCCGGCTGCCAACCAGTGAAGCGCGGCTGGCCAAAGTCCTTGCCGAACTCACGCCGCGCCT
TGCCGCCACTGCTGCCGATCACGACTCGCGCGGTACATTTCCCCATGACAACTTCGCGCTGCTGCACCAGTACGGCCTGA
TCTCACAGGCGGTACCCGTCGCTTCGGGAGGCGGTGGCGCCGGGCTGGCGGAGGCGCGCCGCATCATCGCCGCCGTGGCC
GGTGGAGACGCCGCGACGGCGCTGGTGTTGACGATGACCTACCTGCAGCACCGCGCGATCGGCCGGGACGAGGCACGCTG
GCCGGAGGCGGTGCGCGCGCAGGTGTTCCGCTCGGCCGTGGAAGAGGGGGCGCTGATCAACTCATTGCGCGTAGAGCCGG
AACTGGGCTCGCCGGCACGGGGTGGTCTGCCCGGCACCGTGGCCACGCGCGTGGGCGATCGCTGGCGGCTGCGGGGGCAC
AAGCTCTACAGCACGGGCATCCCCGCGCTGCGCTGGCTGGCGGTCTGGGCGCGCACGCACGAACCGGAGCCGCGGATCGG
GGTGTTCCTTGTGCCGAAGCCCGAAGCCGACACGCCGGGCATCCGTGTGATCGAAAGCTGGAACCACATGGGACTGCGGG
CATCGGGCAGCCATGAGACCTTGCTGGAGGACGTGTGGATCCCGATCGAGCATGCGGTGGATATCCGTCCGCCATCGGCC
TGGGCCCCGGCGGGCGCGAGCCAGGCCGATATCGACGGCAATATCGACCAGCAGGCGTGGATGGTGGTGCTGCTCGGCAG
CCTCTATGACGCCGTGGCGCGTGCCGCGTACGACTGGATTCGGGATTTCGTGCGCGAACGCGCACCTGGCAGTCTTGGCA
AGCCGCTGGCAACCCTGCCGCGTGTGCAGGAGACCATCGGCGAGATTGCCGCGCTGCTGCGCGCCAACGAAGTGCTGCTG
GACGATGCGGCGGGGCGTACCGACGCCGGCACGCCGCCGTCGGCCGAAGATAGCGGGCTGCTCAAGTTCACGGTGACCGG
GAATGCCATCCGCGCAGTGGAGCTGGCGCTGCAACTCTCGGGTAATCACGGCTTGAGCCGCAACAACCCGCTGGAGCGGC
ATTATCGCGATGTGCTCTGCAGCCGCATCCACACCCCCCAGAACGATTCGATCCTGACTGCCGCCGGCCGCGCGGCGCTG
GCCGACTGA

Upstream 100 bases:

>100_bases
TGGGAACCGATGCTCGATATGCGAATTGCGTCGTTATCGCCAGCCCGCTTCGGGCGGTACGCTATGCAGCGATTCGTTCA
CGTCTTCCGAAGGATTCCCG

Downstream 100 bases:

>100_bases
TCCCCGCAACGGAACGTCGCCGTCGTGCTATGTTTGCGGCAAACGTTAGCGGCCGCGACGCCTTGCCCAGGCACGACGGC
CGAATGATCCAGGAGACATG

Product: acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSSSPLRRLPTSEARLAKVLAELTPRLAATAADHDSRGTFPHDNFALLHQYGLISQAVPVASGGGGAGLAEARRIIAAVA
GGDAATALVLTMTYLQHRAIGRDEARWPEAVRAQVFRSAVEEGALINSLRVEPELGSPARGGLPGTVATRVGDRWRLRGH
KLYSTGIPALRWLAVWARTHEPEPRIGVFLVPKPEADTPGIRVIESWNHMGLRASGSHETLLEDVWIPIEHAVDIRPPSA
WAPAGASQADIDGNIDQQAWMVVLLGSLYDAVARAAYDWIRDFVRERAPGSLGKPLATLPRVQETIGEIAALLRANEVLL
DDAAGRTDAGTPPSAEDSGLLKFTVTGNAIRAVELALQLSGNHGLSRNNPLERHYRDVLCSRIHTPQNDSILTAAGRAAL
AD

Sequences:

>Translated_402_residues
MSSSPLRRLPTSEARLAKVLAELTPRLAATAADHDSRGTFPHDNFALLHQYGLISQAVPVASGGGGAGLAEARRIIAAVA
GGDAATALVLTMTYLQHRAIGRDEARWPEAVRAQVFRSAVEEGALINSLRVEPELGSPARGGLPGTVATRVGDRWRLRGH
KLYSTGIPALRWLAVWARTHEPEPRIGVFLVPKPEADTPGIRVIESWNHMGLRASGSHETLLEDVWIPIEHAVDIRPPSA
WAPAGASQADIDGNIDQQAWMVVLLGSLYDAVARAAYDWIRDFVRERAPGSLGKPLATLPRVQETIGEIAALLRANEVLL
DDAAGRTDAGTPPSAEDSGLLKFTVTGNAIRAVELALQLSGNHGLSRNNPLERHYRDVLCSRIHTPQNDSILTAAGRAAL
AD
>Mature_401_residues
SSSPLRRLPTSEARLAKVLAELTPRLAATAADHDSRGTFPHDNFALLHQYGLISQAVPVASGGGGAGLAEARRIIAAVAG
GDAATALVLTMTYLQHRAIGRDEARWPEAVRAQVFRSAVEEGALINSLRVEPELGSPARGGLPGTVATRVGDRWRLRGHK
LYSTGIPALRWLAVWARTHEPEPRIGVFLVPKPEADTPGIRVIESWNHMGLRASGSHETLLEDVWIPIEHAVDIRPPSAW
APAGASQADIDGNIDQQAWMVVLLGSLYDAVARAAYDWIRDFVRERAPGSLGKPLATLPRVQETIGEIAALLRANEVLLD
DAAGRTDAGTPPSAEDSGLLKFTVTGNAIRAVELALQLSGNHGLSRNNPLERHYRDVLCSRIHTPQNDSILTAAGRAALA
D

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=380, Percent_Identity=24.7368421052632, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1786223, Length=377, Percent_Identity=22.5464190981432, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=366, Percent_Identity=25.4098360655738, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=366, Percent_Identity=23.7704918032787, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=26.2162162162162, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 43106; Mature: 42975

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSPLRRLPTSEARLAKVLAELTPRLAATAADHDSRGTFPHDNFALLHQYGLISQAVPV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
ASGGGGAGLAEARRIIAAVAGGDAATALVLTMTYLQHRAIGRDEARWPEAVRAQVFRSAV
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHH
EEGALINSLRVEPELGSPARGGLPGTVATRVGDRWRLRGHKLYSTGIPALRWLAVWARTH
HCCHHHHHEECCCCCCCCCCCCCCCHHHHHCCCCEECCCCEEECCCCHHHHHHHHHHHCC
EPEPRIGVFLVPKPEADTPGIRVIESWNHMGLRASGSHETLLEDVWIPIEHAVDIRPPSA
CCCCCEEEEEEECCCCCCCCCEEEECCCCCCEECCCCHHHHHHHHCCCHHHEEECCCCCC
WAPAGASQADIDGNIDQQAWMVVLLGSLYDAVARAAYDWIRDFVRERAPGSLGKPLATLP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
RVQETIGEIAALLRANEVLLDDAAGRTDAGTPPSAEDSGLLKFTVTGNAIRAVELALQLS
HHHHHHHHHHHHHHHCHHEEECCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEEEC
GNHGLSRNNPLERHYRDVLCSRIHTPQNDSILTAAGRAALAD
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHCCC
>Mature Secondary Structure 
SSSPLRRLPTSEARLAKVLAELTPRLAATAADHDSRGTFPHDNFALLHQYGLISQAVPV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
ASGGGGAGLAEARRIIAAVAGGDAATALVLTMTYLQHRAIGRDEARWPEAVRAQVFRSAV
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHH
EEGALINSLRVEPELGSPARGGLPGTVATRVGDRWRLRGHKLYSTGIPALRWLAVWARTH
HCCHHHHHEECCCCCCCCCCCCCCCHHHHHCCCCEECCCCEEECCCCHHHHHHHHHHHCC
EPEPRIGVFLVPKPEADTPGIRVIESWNHMGLRASGSHETLLEDVWIPIEHAVDIRPPSA
CCCCCEEEEEEECCCCCCCCCEEEECCCCCCEECCCCHHHHHHHHCCCHHHEEECCCCCC
WAPAGASQADIDGNIDQQAWMVVLLGSLYDAVARAAYDWIRDFVRERAPGSLGKPLATLP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
RVQETIGEIAALLRANEVLLDDAAGRTDAGTPPSAEDSGLLKFTVTGNAIRAVELALQLS
HHHHHHHHHHHHHHHCHHEEECCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEEEC
GNHGLSRNNPLERHYRDVLCSRIHTPQNDSILTAAGRAALAD
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]