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The map label for this gene is dnaQ [H]

Identifier: 94311147

GI number: 94311147

Start: 2421305

End: 2422030

Strand: Direct

Name: dnaQ [H]

Synonym: Rmet_2209

Alternate gene names: 94311147

Gene position: 2421305-2422030 (Clockwise)

Preceding gene: 94311146

Following gene: 94311149

Centisome position: 61.64

GC content: 63.36

Gene sequence:

>726_bases
ATGCGACAAATCGTTCTCGATACCGAAACCACCGGCCTTAATCACGCGACAGGCGACCGACTGATCGAAATCGGCTGCGT
GGAACTGGTGAATCGCCGCCTGACAGGCCGCCACCTCCACTTCTACGTCAATCCAGAGCGCGACATCCATGAGGATGCCA
TCGCAGTGCACGGGATCACGCTCGATTTCCTGGCCGACAAGCCCAAGTTCGCCGAGATCGTCAACGACGTCCGCGACTTC
GTGCAGGACGCCGAACTGATCATCCACAACGCGCCCTTCGACCTTGGCTTCCTGGACATGGAGTTCCAGCGCCTGGACCT
GCCGCCGTTCCGCCAGCACGCCAGCAACGTGATCGACACGCTGCGTGAAGCCCGCCAGATGTTCCCGGGCAAGCGCAACT
CGCTGGATGCGCTGTGCGACCGACTTGGCGTCAGCAACTCCCATCGCACGCTGCACGGCGCACTGCTCGATGCCGAACTG
CTCGCCGAGGTCTACCTGGCGATGACGCGCGGCCAGAACTCACTGGTCATCGACATGCTCGACGGCGCCGCCACGGACGG
CGAGACGCGTAGCACCGCCGACCTGTCCGCCATGACGCTGCCCGTGCTATTGGCCTCCGAGGCAGAAATCTCGGCGCACA
TGGGCGTGCTCAAGGAACTCGACAAGGCAAGTGGCGGCAAGACGGTCTGGCAGGAAGCCTCCCCTGCCGAAGCCGCCACT
CAGTAG

Upstream 100 bases:

>100_bases
CGCGGTCACAACGGGCACCCCGGCAACGAACGCGCGGATGCGCTGGCCAATCGCGGGGTGGCGTCGATCAATACCTGACC
CGTCGTTTACAATCCCGCCC

Downstream 100 bases:

>100_bases
GGCCTGGCGCCTCCCGAGGGATTTCGAAGAAAATTCGAAAAAGGGCTTTACAAGATACCGGCCCATCGGCATAATCTCGT
TTCTCCACTGCGCGACATCA

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MRQIVLDTETTGLNHATGDRLIEIGCVELVNRRLTGRHLHFYVNPERDIHEDAIAVHGITLDFLADKPKFAEIVNDVRDF
VQDAELIIHNAPFDLGFLDMEFQRLDLPPFRQHASNVIDTLREARQMFPGKRNSLDALCDRLGVSNSHRTLHGALLDAEL
LAEVYLAMTRGQNSLVIDMLDGAATDGETRSTADLSAMTLPVLLASEAEISAHMGVLKELDKASGGKTVWQEASPAEAAT
Q

Sequences:

>Translated_241_residues
MRQIVLDTETTGLNHATGDRLIEIGCVELVNRRLTGRHLHFYVNPERDIHEDAIAVHGITLDFLADKPKFAEIVNDVRDF
VQDAELIIHNAPFDLGFLDMEFQRLDLPPFRQHASNVIDTLREARQMFPGKRNSLDALCDRLGVSNSHRTLHGALLDAEL
LAEVYLAMTRGQNSLVIDMLDGAATDGETRSTADLSAMTLPVLLASEAEISAHMGVLKELDKASGGKTVWQEASPAEAAT
Q
>Mature_241_residues
MRQIVLDTETTGLNHATGDRLIEIGCVELVNRRLTGRHLHFYVNPERDIHEDAIAVHGITLDFLADKPKFAEIVNDVRDF
VQDAELIIHNAPFDLGFLDMEFQRLDLPPFRQHASNVIDTLREARQMFPGKRNSLDALCDRLGVSNSHRTLHGALLDAEL
LAEVYLAMTRGQNSLVIDMLDGAATDGETRSTADLSAMTLPVLLASEAEISAHMGVLKELDKASGGKTVWQEASPAEAAT
Q

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=239, Percent_Identity=50.6276150627615, Blast_Score=224, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26591; Mature: 26591

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIVLDTETTGLNHATGDRLIEIGCVELVNRRLTGRHLHFYVNPERDIHEDAIAVHGIT
CCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHEEEECEE
LDFLADKPKFAEIVNDVRDFVQDAELIIHNAPFDLGFLDMEFQRLDLPPFRQHASNVIDT
EEECCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCEECCHHHHCCCCHHHHHHHHHHHH
LREARQMFPGKRNSLDALCDRLGVSNSHRTLHGALLDAELLAEVYLAMTRGQNSLVIDML
HHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DGAATDGETRSTADLSAMTLPVLLASEAEISAHMGVLKELDKASGGKTVWQEASPAEAAT
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCC
Q
C
>Mature Secondary Structure
MRQIVLDTETTGLNHATGDRLIEIGCVELVNRRLTGRHLHFYVNPERDIHEDAIAVHGIT
CCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHEEEECEE
LDFLADKPKFAEIVNDVRDFVQDAELIIHNAPFDLGFLDMEFQRLDLPPFRQHASNVIDT
EEECCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCEECCHHHHCCCCHHHHHHHHHHHH
LREARQMFPGKRNSLDALCDRLGVSNSHRTLHGALLDAELLAEVYLAMTRGQNSLVIDML
HHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
DGAATDGETRSTADLSAMTLPVLLASEAEISAHMGVLKELDKASGGKTVWQEASPAEAAT
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]