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The map label for this gene is rdxI [H]

Identifier: 94310984

GI number: 94310984

Start: 2212650

End: 2215235

Strand: Reverse

Name: rdxI [H]

Synonym: Rmet_2046

Alternate gene names: 94310984

Gene position: 2215235-2212650 (Counterclockwise)

Preceding gene: 335055577

Following gene: 94310983

Centisome position: 56.39

GC content: 66.32

Gene sequence:

>2586_bases
ATGCCGTCCCTGCACGCTAGCCCCCTCGCGCCCGATGGAACGTCCGTTCCGTCCAATCCGAGCGCACAACTTGGTTCCGC
CGCAGCCCTTGCCTCGGGCACGCGGCTTGGGTCGGCGTCTCTATCTACATCCACTACTCATTGTTTTCATTGCGGCCAGC
CTCTCGGGCGCGATGTCACGCCGCTCGTCGCTGATATCGGCGGGCAGCGCCGCACATTCTGCTGTGGCGGCTGCCAGGCG
CTGGCGCAGACACTCTATTCAGCCGGCTTCGGGCATCTATATAGCGATGTCACGCGGTTCGCGCGGCCGATAGATGCCCA
GGCGCGACGCGAGGCAGAGCCTGTGTGGGCCGCCTACGATACCCCCGAGCTGCGCAACCAGTTCGTTCGCGAACTGGGCG
ACGGCCGGGCGGAGATCACGCTGGCGCCGGAAAACATCCGCTGCGCGGCCTGTGCCTGGCTGATCGAGCAGCACCTCGGG
CAACTGGATGGGGTCGAGTCGGCCGTGGCGAACGTGGCCACGCGCCGCGTAGTGGTGCGCTGGCAAGAGAACAAGCAGGG
CGTGGCGGGGCTGCTGTCCACGCTGGCCGACATCGGCTATCAGGCATGGCCGTTCGAGGTGTCGCGTGGCGACCAGCACG
ATCGCCGCGAGCGGCGCGGCTTGCTGATGCGCATGGCCGTGGCGATGCTCGGCATGATGCAGGTGATGATGTATGCGTGG
CCGCTCTATACGCACGAAGCCACGATCGACCCCGGCCAGCTTCAGTTGATGCGCTGGGCGAGCTTTGCGCTGACGATCCC
GGTGGTTCTTTACTCTGCCTCGCCGATTTTCGCTGGCGCATGGCGTTCATTGCGGCAACGACATATGGGCATGGACGTGC
CTGTTGCGATCGGCGTGCTGGCTGGCTTCTTCGCGAGCGCTGTGGCGACCGTGCGGGGCGTCGGGGAGGTCTACTTCGAT
TCCGTGACGATGTTCGTCGCGTTCCTTCTGTTGGCCCGCTATCTGGAGTTGCGTGTCCGGCAAGCCTCGCGCAGTGGCGC
CGAGATGCTGGCGCGCCAGCTGCCCGCGACCTGCGAGCGGCTGGTGGAGACGAGCGGCGTCGGCGAGCGGATCCCGGTTG
CGCGACTGAATGCCGGTGACCGGATTCGCGTGAAGGCGGGCGAGATCATGCCGGCCGACGGTGTCGTGGTGGCTGGCGTC
AGCGAAATCGACGAATCGATGCTGACAGGGGAAGCGCGGCCGGTGAAGCGCGCCATTGGCGACACCGTGCTGGCGGGTTG
TTTCAATGCTGCCAGTCCGCTCGAGGTGAGCGTGCGCCGGATCGGCGCGCAGACCCGTCTCGCCGAGATCGTAGCCGTGC
TGGATCGCGCGCTGGCGGATAAGCCCCGCCTGGCCCAGTTGGCAGATCGTGTGGCCGGCTGGTTTGTCGCCACCCTCTTG
ATCCTGGCCGCAATCACCGGGCTGGTCTGGGCGATCTGGATCGATCCATCACGCGCGCTATTGGTGACAGTCGCGGTGCT
CGTTGTGAGCTGTCCTTGCGCGTTGTCGCTGGCTACTCCGGCGGCGCTGGCCGCCGCTGGCGCGGCGTTGTCGCGGCGCG
GCGTGCTGCTGACCCGCGCGCACACGCTCGAAGCGCTTTCGGGTGTCACGGACATCATGCTCGACAAGACGGGCACGTTG
ACCGAGGGGCGTTTTGCGCTCGTGTCGACGGAGATCGCGGGCAATCTGGATGCGCCGACTTGCCAGAGTCTCGCCGCCGC
CATGGAGCGTGGTGGGGAACATCCGATTGCGAGGGCCTTGGTTGAGGCCGCGGCGGACCATGCCGAACGGCTGGTGGCTG
AACTGCACAACACTCCCGGGCAAGGATTGCAGGCAAATGTCGACGGCCGGTTGATGCGGCTGGGGCGTAGAGAGTTCGTC
GCGGAATTGGCACCGGCAGCAGCCGACATCCGCCGCAGTGGTGACCGTTTTCCGGGCGCTACCGAGGTCTGGCTTGGTGA
CGCAAACGGTCCGCTGGCGTGTTTTCAGTTGGCCGATGTCGAACGGCCCCAGACAGCCGAGCTTCTGGCTTCGCTGACCC
GACTCGGTGTGCGCTGTCATCTGGTTTCGGGCGATCAGCCGGCAGCGGTGCGCTGGTGGGCGGACCGCTTCGGCATCGAG
ACCGCCGTTGGAGCGGTCACGCCTGAAGGCAAGCGCGACTATGTAGCCAATCTTCAACAGCAGGGCGCCGTCGTTCTGGC
GGTGGGCGACGGCATCAACGATGCGCCGGTGCTGGCCCAGGCCCAGGTTTCGATAGCGATCGGCAGCGGTGCGCCATTGG
CGCAGGCCGGTGCCGATGCCGTGCTGACACACGGTGGCGTGGGCGAAATCGCCAATGCCATTGCCGTGGCCCGCAAGACG
CGCCGTGTGGTACGCCAGAACCTGGGTTGGGCCTTTTTCTACAACGTCGTGGCGATCCCCCTGGCAGCTACCGGACTCGT
TACGGCATGGATGGCAGGCATCGGAATGTCCGTGTCGTCGTTACTGGTTGTCGGCAATGCATGGCGCCTGTTGCGCGCCG
CGGCGGCGCCGGCCAGGGAGTCCTGA

Upstream 100 bases:

>100_bases
TTGCACGGCCAGACCCTGACTCCATTTTTGGAAGTTTGATCTTTATCAAGGCATATGGCGCGCTGGTTACCTAGTATTCG
CTGGGTACTAAAAGCGCACT

Downstream 100 bases:

>100_bases
ATATGGAAACACTCTATCTATTGGTGCCGATGAGCCTGGTGCTGGTGGCCGTGATTGCCGGGGCGCTGTGGTGGGCGTTG
CACGCGGGGCAGTACGACGA

Product: heavy metal transporting P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 861; Mature: 860

Protein sequence:

>861_residues
MPSLHASPLAPDGTSVPSNPSAQLGSAAALASGTRLGSASLSTSTTHCFHCGQPLGRDVTPLVADIGGQRRTFCCGGCQA
LAQTLYSAGFGHLYSDVTRFARPIDAQARREAEPVWAAYDTPELRNQFVRELGDGRAEITLAPENIRCAACAWLIEQHLG
QLDGVESAVANVATRRVVVRWQENKQGVAGLLSTLADIGYQAWPFEVSRGDQHDRRERRGLLMRMAVAMLGMMQVMMYAW
PLYTHEATIDPGQLQLMRWASFALTIPVVLYSASPIFAGAWRSLRQRHMGMDVPVAIGVLAGFFASAVATVRGVGEVYFD
SVTMFVAFLLLARYLELRVRQASRSGAEMLARQLPATCERLVETSGVGERIPVARLNAGDRIRVKAGEIMPADGVVVAGV
SEIDESMLTGEARPVKRAIGDTVLAGCFNAASPLEVSVRRIGAQTRLAEIVAVLDRALADKPRLAQLADRVAGWFVATLL
ILAAITGLVWAIWIDPSRALLVTVAVLVVSCPCALSLATPAALAAAGAALSRRGVLLTRAHTLEALSGVTDIMLDKTGTL
TEGRFALVSTEIAGNLDAPTCQSLAAAMERGGEHPIARALVEAAADHAERLVAELHNTPGQGLQANVDGRLMRLGRREFV
AELAPAAADIRRSGDRFPGATEVWLGDANGPLACFQLADVERPQTAELLASLTRLGVRCHLVSGDQPAAVRWWADRFGIE
TAVGAVTPEGKRDYVANLQQQGAVVLAVGDGINDAPVLAQAQVSIAIGSGAPLAQAGADAVLTHGGVGEIANAIAVARKT
RRVVRQNLGWAFFYNVVAIPLAATGLVTAWMAGIGMSVSSLLVVGNAWRLLRAAAAPARES

Sequences:

>Translated_861_residues
MPSLHASPLAPDGTSVPSNPSAQLGSAAALASGTRLGSASLSTSTTHCFHCGQPLGRDVTPLVADIGGQRRTFCCGGCQA
LAQTLYSAGFGHLYSDVTRFARPIDAQARREAEPVWAAYDTPELRNQFVRELGDGRAEITLAPENIRCAACAWLIEQHLG
QLDGVESAVANVATRRVVVRWQENKQGVAGLLSTLADIGYQAWPFEVSRGDQHDRRERRGLLMRMAVAMLGMMQVMMYAW
PLYTHEATIDPGQLQLMRWASFALTIPVVLYSASPIFAGAWRSLRQRHMGMDVPVAIGVLAGFFASAVATVRGVGEVYFD
SVTMFVAFLLLARYLELRVRQASRSGAEMLARQLPATCERLVETSGVGERIPVARLNAGDRIRVKAGEIMPADGVVVAGV
SEIDESMLTGEARPVKRAIGDTVLAGCFNAASPLEVSVRRIGAQTRLAEIVAVLDRALADKPRLAQLADRVAGWFVATLL
ILAAITGLVWAIWIDPSRALLVTVAVLVVSCPCALSLATPAALAAAGAALSRRGVLLTRAHTLEALSGVTDIMLDKTGTL
TEGRFALVSTEIAGNLDAPTCQSLAAAMERGGEHPIARALVEAAADHAERLVAELHNTPGQGLQANVDGRLMRLGRREFV
AELAPAAADIRRSGDRFPGATEVWLGDANGPLACFQLADVERPQTAELLASLTRLGVRCHLVSGDQPAAVRWWADRFGIE
TAVGAVTPEGKRDYVANLQQQGAVVLAVGDGINDAPVLAQAQVSIAIGSGAPLAQAGADAVLTHGGVGEIANAIAVARKT
RRVVRQNLGWAFFYNVVAIPLAATGLVTAWMAGIGMSVSSLLVVGNAWRLLRAAAAPARES
>Mature_860_residues
PSLHASPLAPDGTSVPSNPSAQLGSAAALASGTRLGSASLSTSTTHCFHCGQPLGRDVTPLVADIGGQRRTFCCGGCQAL
AQTLYSAGFGHLYSDVTRFARPIDAQARREAEPVWAAYDTPELRNQFVRELGDGRAEITLAPENIRCAACAWLIEQHLGQ
LDGVESAVANVATRRVVVRWQENKQGVAGLLSTLADIGYQAWPFEVSRGDQHDRRERRGLLMRMAVAMLGMMQVMMYAWP
LYTHEATIDPGQLQLMRWASFALTIPVVLYSASPIFAGAWRSLRQRHMGMDVPVAIGVLAGFFASAVATVRGVGEVYFDS
VTMFVAFLLLARYLELRVRQASRSGAEMLARQLPATCERLVETSGVGERIPVARLNAGDRIRVKAGEIMPADGVVVAGVS
EIDESMLTGEARPVKRAIGDTVLAGCFNAASPLEVSVRRIGAQTRLAEIVAVLDRALADKPRLAQLADRVAGWFVATLLI
LAAITGLVWAIWIDPSRALLVTVAVLVVSCPCALSLATPAALAAAGAALSRRGVLLTRAHTLEALSGVTDIMLDKTGTLT
EGRFALVSTEIAGNLDAPTCQSLAAAMERGGEHPIARALVEAAADHAERLVAELHNTPGQGLQANVDGRLMRLGRREFVA
ELAPAAADIRRSGDRFPGATEVWLGDANGPLACFQLADVERPQTAELLASLTRLGVRCHLVSGDQPAAVRWWADRFGIET
AVGAVTPEGKRDYVANLQQQGAVVLAVGDGINDAPVLAQAQVSIAIGSGAPLAQAGADAVLTHGGVGEIANAIAVARKTR
RVVRQNLGWAFFYNVVAIPLAATGLVTAWMAGIGMSVSSLLVVGNAWRLLRAAAAPARES

Specific function: Involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=801, Percent_Identity=27.5905118601748, Blast_Score=268, Evalue=2e-71,
Organism=Homo sapiens, GI115529486, Length=595, Percent_Identity=24.3697478991597, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI55743073, Length=501, Percent_Identity=28.3433133732535, Blast_Score=182, Evalue=2e-45,
Organism=Escherichia coli, GI1786691, Length=737, Percent_Identity=30.5291723202171, Blast_Score=288, Evalue=1e-78,
Organism=Escherichia coli, GI1789879, Length=719, Percent_Identity=29.4853963838665, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI1786914, Length=436, Percent_Identity=28.6697247706422, Blast_Score=126, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17556548, Length=795, Percent_Identity=25.2830188679245, Blast_Score=218, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6319772, Length=650, Percent_Identity=28.6153846153846, Blast_Score=247, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6320475, Length=752, Percent_Identity=26.5957446808511, Blast_Score=247, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6321430, Length=559, Percent_Identity=21.824686940966, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6325221, Length=559, Percent_Identity=21.6457960644007, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI221329854, Length=531, Percent_Identity=27.683615819209, Blast_Score=179, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR001366
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 91153; Mature: 91022

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00154 ATPASE_E1_E2 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLHASPLAPDGTSVPSNPSAQLGSAAALASGTRLGSASLSTSTTHCFHCGQPLGRDVT
CCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHCCCCCCCCCCCCCCCHHEECCCCCCCCCH
PLVADIGGQRRTFCCGGCQALAQTLYSAGFGHLYSDVTRFARPIDAQARREAEPVWAAYD
HHHHHCCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCCEEECC
TPELRNQFVRELGDGRAEITLAPENIRCAACAWLIEQHLGQLDGVESAVANVATRRVVVR
CHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEE
WQENKQGVAGLLSTLADIGYQAWPFEVSRGDQHDRRERRGLLMRMAVAMLGMMQVMMYAW
ECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLYTHEATIDPGQLQLMRWASFALTIPVVLYSASPIFAGAWRSLRQRHMGMDVPVAIGVL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
AGFFASAVATVRGVGEVYFDSVTMFVAFLLLARYLELRVRQASRSGAEMLARQLPATCER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHH
LVETSGVGERIPVARLNAGDRIRVKAGEIMPADGVVVAGVSEIDESMLTGEARPVKRAIG
HHHHCCCCCCCCEEECCCCCEEEEEECCCCCCCCEEECCHHHHHHHHHCCCCHHHHHHHH
DTVLAGCFNAASPLEVSVRRIGAQTRLAEIVAVLDRALADKPRLAQLADRVAGWFVATLL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ILAAITGLVWAIWIDPSRALLVTVAVLVVSCPCALSLATPAALAAAGAALSRRGVLLTRA
HHHHHHHHHEEEEECCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCEEEEHH
HTLEALSGVTDIMLDKTGTLTEGRFALVSTEIAGNLDAPTCQSLAAAMERGGEHPIARAL
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHHCCCCCHHHHHH
VEAAADHAERLVAELHNTPGQGLQANVDGRLMRLGRREFVAELAPAAADIRRSGDRFPGA
HHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TEVWLGDANGPLACFQLADVERPQTAELLASLTRLGVRCHLVSGDQPAAVRWWADRFGIE
CEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCHH
TAVGAVTPEGKRDYVANLQQQGAVVLAVGDGINDAPVLAQAQVSIAIGSGAPLAQAGADA
HHHCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCHHHCCCCC
VLTHGGVGEIANAIAVARKTRRVVRQNLGWAFFYNVVAIPLAATGLVTAWMAGIGMSVSS
EEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LLVVGNAWRLLRAAAAPARES
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PSLHASPLAPDGTSVPSNPSAQLGSAAALASGTRLGSASLSTSTTHCFHCGQPLGRDVT
CCCCCCCCCCCCCCCCCCCCHHHCCHHHHHCCCCCCCCCCCCCCCHHEECCCCCCCCCH
PLVADIGGQRRTFCCGGCQALAQTLYSAGFGHLYSDVTRFARPIDAQARREAEPVWAAYD
HHHHHCCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCCEEECC
TPELRNQFVRELGDGRAEITLAPENIRCAACAWLIEQHLGQLDGVESAVANVATRRVVVR
CHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEE
WQENKQGVAGLLSTLADIGYQAWPFEVSRGDQHDRRERRGLLMRMAVAMLGMMQVMMYAW
ECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLYTHEATIDPGQLQLMRWASFALTIPVVLYSASPIFAGAWRSLRQRHMGMDVPVAIGVL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
AGFFASAVATVRGVGEVYFDSVTMFVAFLLLARYLELRVRQASRSGAEMLARQLPATCER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHH
LVETSGVGERIPVARLNAGDRIRVKAGEIMPADGVVVAGVSEIDESMLTGEARPVKRAIG
HHHHCCCCCCCCEEECCCCCEEEEEECCCCCCCCEEECCHHHHHHHHHCCCCHHHHHHHH
DTVLAGCFNAASPLEVSVRRIGAQTRLAEIVAVLDRALADKPRLAQLADRVAGWFVATLL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ILAAITGLVWAIWIDPSRALLVTVAVLVVSCPCALSLATPAALAAAGAALSRRGVLLTRA
HHHHHHHHHEEEEECCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCEEEEHH
HTLEALSGVTDIMLDKTGTLTEGRFALVSTEIAGNLDAPTCQSLAAAMERGGEHPIARAL
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHHCCCCCHHHHHH
VEAAADHAERLVAELHNTPGQGLQANVDGRLMRLGRREFVAELAPAAADIRRSGDRFPGA
HHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TEVWLGDANGPLACFQLADVERPQTAELLASLTRLGVRCHLVSGDQPAAVRWWADRFGIE
CEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCHH
TAVGAVTPEGKRDYVANLQQQGAVVLAVGDGINDAPVLAQAQVSIAIGSGAPLAQAGADA
HHHCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEEECCCCCHHHCCCCC
VLTHGGVGEIANAIAVARKTRRVVRQNLGWAFFYNVVAIPLAATGLVTAWMAGIGMSVSS
EEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LLVVGNAWRLLRAAAAPARES
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA