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The map label for this gene is moaE [H]

Identifier: 94310900

GI number: 94310900

Start: 2138178

End: 2138669

Strand: Reverse

Name: moaE [H]

Synonym: Rmet_1962

Alternate gene names: 94310900

Gene position: 2138669-2138178 (Counterclockwise)

Preceding gene: 94310901

Following gene: 94310899

Centisome position: 54.45

GC content: 66.26

Gene sequence:

>492_bases
ATGGCGGTGCGCGTTCAGCACGAGGATTTCGATCTCGGCGCGGAAGTGGCGGCGCTGCGCGCCGGCAATCCGGGCGTTGG
GGCGGTGGCCAGCTTCATCGGAACGGTGCGCGATGTCAGCGAAGGCACGCGCGTCAGTACGATGGAGCTCGAGCACTATC
CCGGCATGACCGAGAAGGCGCTGGAGACGATCGAGGCGGCGGCGCGCGAACGCTGGCCGCTGCTTGGCGTGACCATCGTG
CATCGCGTGGGCCTGCTGCAGCCGCTGGACCAGATCGTGCTGGTTGCCGTGTCCTCGGCCCACCGTGGGGCCGCGTTTGC
GGCGTGCGAGTTCATCATGGACTATCTGAAGTCCGAGGCACCGTTCTGGAAGAAAGAAGACACGCCGGAAGGCGCGCGCT
GGGTCGACGCGCGGGTCTCGGACGATGCCGCGCTGCGCCGCTGGGGTATCGAATCGTTCAACGCGGATCCCGCCAATAAC
AAGGAAGAATGA

Upstream 100 bases:

>100_bases
GCGCTGCGCATGGCCGTGGACCACGCCGTGGCACGTGCCGACACCCCGCTGGCCGACGGCTGCGAGGTGGCCTTTTTCCC
TCCCGTGACCGGAGGCTGAG

Downstream 100 bases:

>100_bases
TGGGCCCGATGGGTTTCGTGGCGGTCGGCGTCGGTGCCGCCGTCGGCGCCTGGCTGCGCTGGTTTTTCTCGGTCACGTGG
AACGCTATCAATCCGGCACT

Product: molybdopterin synthase, large subunit

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MAVRVQHEDFDLGAEVAALRAGNPGVGAVASFIGTVRDVSEGTRVSTMELEHYPGMTEKALETIEAAARERWPLLGVTIV
HRVGLLQPLDQIVLVAVSSAHRGAAFAACEFIMDYLKSEAPFWKKEDTPEGARWVDARVSDDAALRRWGIESFNADPANN
KEE

Sequences:

>Translated_163_residues
MAVRVQHEDFDLGAEVAALRAGNPGVGAVASFIGTVRDVSEGTRVSTMELEHYPGMTEKALETIEAAARERWPLLGVTIV
HRVGLLQPLDQIVLVAVSSAHRGAAFAACEFIMDYLKSEAPFWKKEDTPEGARWVDARVSDDAALRRWGIESFNADPANN
KEE
>Mature_162_residues
AVRVQHEDFDLGAEVAALRAGNPGVGAVASFIGTVRDVSEGTRVSTMELEHYPGMTEKALETIEAAARERWPLLGVTIVH
RVGLLQPLDQIVLVAVSSAHRGAAFAACEFIMDYLKSEAPFWKKEDTPEGARWVDARVSDDAALRRWGIESFNADPANNK
EE

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=112, Percent_Identity=37.5, Blast_Score=94, Evalue=6e-20,
Organism=Escherichia coli, GI1787003, Length=122, Percent_Identity=60.655737704918, Blast_Score=154, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21356259, Length=119, Percent_Identity=34.453781512605, Blast_Score=76, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17819; Mature: 17688

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRVQHEDFDLGAEVAALRAGNPGVGAVASFIGTVRDVSEGTRVSTMELEHYPGMTEKA
CEEEECCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCHHHH
LETIEAAARERWPLLGVTIVHRVGLLQPLDQIVLVAVSSAHRGAAFAACEFIMDYLKSEA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
PFWKKEDTPEGARWVDARVSDDAALRRWGIESFNADPANNKEE
CCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AVRVQHEDFDLGAEVAALRAGNPGVGAVASFIGTVRDVSEGTRVSTMELEHYPGMTEKA
EEEECCCCCCCCHHHHHEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCHHHH
LETIEAAARERWPLLGVTIVHRVGLLQPLDQIVLVAVSSAHRGAAFAACEFIMDYLKSEA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
PFWKKEDTPEGARWVDARVSDDAALRRWGIESFNADPANNKEE
CCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]