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The map label for this gene is argE1 [H]

Identifier: 94310894

GI number: 94310894

Start: 2128466

End: 2129701

Strand: Direct

Name: argE1 [H]

Synonym: Rmet_1956

Alternate gene names: 94310894

Gene position: 2128466-2129701 (Clockwise)

Preceding gene: 94310893

Following gene: 94310906

Centisome position: 54.19

GC content: 65.05

Gene sequence:

>1236_bases
ATGAATCAGACGTTTCAACGCCCCATGCCAGCCCAACCCGACAACCGATCCGCCGCCACCAATGCCCCCGCGCGTGGCAG
CGCGCTCGAATGGACCGAGCGCCTGGTATCGATGGATACCACTTCCCGCCATTCGAATCTGGGCCTGATCGAGTCCGTGC
GCGACCACTTCCTGGCCAAGGGCCTGCGCCCCCATCTGAGCTACAACCCGCAGGGCGACAAGGCCAACCTGTTCGTGACG
ATTCCCGCAGCCGATGGCGCCACCAATGGTGGCATCGTGCTGTCCGGGCACACGGACGTGGTGCCCGTCGACGGGCAGAA
CTGGAGCACCGACCCGTTCAAGCCGGTGGTGCGCGACGGCAAGCTCTACGGTCGCGGCACCTGTGACATGAAGGGGTTCA
TCGGCACGAGCCTGGCGCTGCTGCCGACCATCCTTGATGCCAGGCTGCGCGAGCCAGTGCACTACGCACTGTCGTTCGAC
GAAGAGATCGGCTGCATGGGCGCGCCGTACCTGCTGGCCGAACTGCGTGACCGTGGCGTGCGCCCGGCGGGCTGCATCGT
CGGCGAGCCGACCAGCATGCGCGTGATCGTGGCGCACAAGGGCATCAATGCCTACCGGTGCTGCGTTAAGGGCCAGGCGG
CGCACTCGTCGCTGACCCCTAAGGGCGTCAATGCGATCGAGTACGCCGCGCGCCTGATCTGTTTCATTCGCGATATTGCC
GACGAGTTCAAGGCCAATGGCCCTTACGACCGGGCCTTCGACGTGCCGTTTACGACCGCTTCGACCGGCACGATCCAGGG
TGGCATCGCGCTAAACACCATTCCCGCCGAGTGCGAATTCGTCTTCGAGTTCCGGAATCTTCCTGGCGTTGATCCGGAAG
CGATCCTGGCGCGCATCCAGGCCTACGCGAACGATGTGCTGTTGCCGAAGATGCGCAACGAGCATCCGGATGCCGGCATG
GCCATCAGCAAGATCGCCGCCGCGCCTTCGCTCGATGCCGCCGAGACCGATGCCATTACCCAGCTCGTACGCGCGCTGAC
CGCCGACCGCGATACCAACAAGGTGGCCTACGGCACCGAGGCTGGCCTGTTCCAGCGCGCAGGCATTCCGGCTGTGGTGT
GCGGCCCCGGCGATATCCAGCAGGCGCACAAGCCCGACGAGTTCGTCTCGCTGGATCAGCTTGCCGCGTGCGAGACCTTC
CTGCACAAGGTGGTGGATAGCCTGCGCGTCGCCTGA

Upstream 100 bases:

>100_bases
CGAGGCAAAGATGCCCGACGTGGCTACCCGCGCGCAAACCATCAAGCACACGCTGCGCCAGTTGGCCTGATGCCGGGCCA
GGTGTACGATCAAACCCCCA

Downstream 100 bases:

>100_bases
TTCGGCCCCGTGAAAGCGGGGCCACGGACAGGGCAAAGACCAAGACCAAAAAACGGGGTCACCAACGCCGGCCCGCAAAA
AGAAAAAACCCGCGGCACCG

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNQTFQRPMPAQPDNRSAATNAPARGSALEWTERLVSMDTTSRHSNLGLIESVRDHFLAKGLRPHLSYNPQGDKANLFVT
IPAADGATNGGIVLSGHTDVVPVDGQNWSTDPFKPVVRDGKLYGRGTCDMKGFIGTSLALLPTILDARLREPVHYALSFD
EEIGCMGAPYLLAELRDRGVRPAGCIVGEPTSMRVIVAHKGINAYRCCVKGQAAHSSLTPKGVNAIEYAARLICFIRDIA
DEFKANGPYDRAFDVPFTTASTGTIQGGIALNTIPAECEFVFEFRNLPGVDPEAILARIQAYANDVLLPKMRNEHPDAGM
AISKIAAAPSLDAAETDAITQLVRALTADRDTNKVAYGTEAGLFQRAGIPAVVCGPGDIQQAHKPDEFVSLDQLAACETF
LHKVVDSLRVA

Sequences:

>Translated_411_residues
MNQTFQRPMPAQPDNRSAATNAPARGSALEWTERLVSMDTTSRHSNLGLIESVRDHFLAKGLRPHLSYNPQGDKANLFVT
IPAADGATNGGIVLSGHTDVVPVDGQNWSTDPFKPVVRDGKLYGRGTCDMKGFIGTSLALLPTILDARLREPVHYALSFD
EEIGCMGAPYLLAELRDRGVRPAGCIVGEPTSMRVIVAHKGINAYRCCVKGQAAHSSLTPKGVNAIEYAARLICFIRDIA
DEFKANGPYDRAFDVPFTTASTGTIQGGIALNTIPAECEFVFEFRNLPGVDPEAILARIQAYANDVLLPKMRNEHPDAGM
AISKIAAAPSLDAAETDAITQLVRALTADRDTNKVAYGTEAGLFQRAGIPAVVCGPGDIQQAHKPDEFVSLDQLAACETF
LHKVVDSLRVA
>Mature_411_residues
MNQTFQRPMPAQPDNRSAATNAPARGSALEWTERLVSMDTTSRHSNLGLIESVRDHFLAKGLRPHLSYNPQGDKANLFVT
IPAADGATNGGIVLSGHTDVVPVDGQNWSTDPFKPVVRDGKLYGRGTCDMKGFIGTSLALLPTILDARLREPVHYALSFD
EEIGCMGAPYLLAELRDRGVRPAGCIVGEPTSMRVIVAHKGINAYRCCVKGQAAHSSLTPKGVNAIEYAARLICFIRDIA
DEFKANGPYDRAFDVPFTTASTGTIQGGIALNTIPAECEFVFEFRNLPGVDPEAILARIQAYANDVLLPKMRNEHPDAGM
AISKIAAAPSLDAAETDAITQLVRALTADRDTNKVAYGTEAGLFQRAGIPAVVCGPGDIQQAHKPDEFVSLDQLAACETF
LHKVVDSLRVA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=380, Percent_Identity=33.6842105263158, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1788816, Length=338, Percent_Identity=28.4023668639053, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17551016, Length=350, Percent_Identity=26.8571428571429, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 44195; Mature: 44195

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQTFQRPMPAQPDNRSAATNAPARGSALEWTERLVSMDTTSRHSNLGLIESVRDHFLAK
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
GLRPHLSYNPQGDKANLFVTIPAADGATNGGIVLSGHTDVVPVDGQNWSTDPFKPVVRDG
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCEEECCCCCCCCCCCCHHHHCC
KLYGRGTCDMKGFIGTSLALLPTILDARLREPVHYALSFDEEIGCMGAPYLLAELRDRGV
CEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCC
RPAGCIVGEPTSMRVIVAHKGINAYRCCVKGQAAHSSLTPKGVNAIEYAARLICFIRDIA
CCCCCEEECCCCEEEEEEECCCCCEEHEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHHH
DEFKANGPYDRAFDVPFTTASTGTIQGGIALNTIPAECEFVFEFRNLPGVDPEAILARIQ
HHHCCCCCCCCEECCCCCCCCCCEEECCEEEECCCCCCEEEEEECCCCCCCHHHHHHHHH
AYANDVLLPKMRNEHPDAGMAISKIAAAPSLDAAETDAITQLVRALTADRDTNKVAYGTE
HHHCCEECCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCC
AGLFQRAGIPAVVCGPGDIQQAHKPDEFVSLDQLAACETFLHKVVDSLRVA
CCHHHHCCCCEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQTFQRPMPAQPDNRSAATNAPARGSALEWTERLVSMDTTSRHSNLGLIESVRDHFLAK
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
GLRPHLSYNPQGDKANLFVTIPAADGATNGGIVLSGHTDVVPVDGQNWSTDPFKPVVRDG
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCEEECCCCCCCCCCCCHHHHCC
KLYGRGTCDMKGFIGTSLALLPTILDARLREPVHYALSFDEEIGCMGAPYLLAELRDRGV
CEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCC
RPAGCIVGEPTSMRVIVAHKGINAYRCCVKGQAAHSSLTPKGVNAIEYAARLICFIRDIA
CCCCCEEECCCCEEEEEEECCCCCEEHEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHHH
DEFKANGPYDRAFDVPFTTASTGTIQGGIALNTIPAECEFVFEFRNLPGVDPEAILARIQ
HHHCCCCCCCCEECCCCCCCCCCEEECCEEEECCCCCCEEEEEECCCCCCCHHHHHHHHH
AYANDVLLPKMRNEHPDAGMAISKIAAAPSLDAAETDAITQLVRALTADRDTNKVAYGTE
HHHCCEECCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCC
AGLFQRAGIPAVVCGPGDIQQAHKPDEFVSLDQLAACETFLHKVVDSLRVA
CCHHHHCCCCEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]