| Definition | Cupriavidus metallidurans CH34 chromosome, complete genome. |
|---|---|
| Accession | NC_007973 |
| Length | 3,928,089 |
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The map label for this gene is ilvX [H]
Identifier: 94310833
GI number: 94310833
Start: 2062686
End: 2064230
Strand: Direct
Name: ilvX [H]
Synonym: Rmet_1895
Alternate gene names: 94310833
Gene position: 2062686-2064230 (Clockwise)
Preceding gene: 335055561
Following gene: 94310834
Centisome position: 52.51
GC content: 67.44
Gene sequence:
>1545_bases ATGAACGGTGCGGAAAGTCTGTTGCGTTCGCTGGTGGCGTGTGGCGTGGAGGTGTGTTTTGGCAATCCGGGCACGTCGGA GATGCATTTCGTGGCGGCGCTCGATGCGGTGGATGGCATGCGCCCCGTCCTTGGCCTGTTCGAAGGCGTGGTCACTGGCG CGGCCGACGGCTACGGTCGCATGGCAGGAAAGCCTGCCGCCACGCTGCTGCATCTGGGTCCGGGCCTGACCAATGGCCTG GCCAACCTGCACAACGCGCGGCGCGCATCGAGCCCGATCGTCAACATCGTCGGCGACCATGCAGCCTCTCATTCACGCTA CGAGGCACCGCTGACTTCCGATATCCAGGGATTCGCGCGGCCGGTATCGCAATGGATTCACGCATCCGCAAGCGCGCTGA CGGTTGGCGCCGACGCCGCGCGCGCCGTGCAAGCGTCGATGGAGGCACCCGGCCAGGTGGCCACACTGATCCTGCCTGCG GATACCGCCTGGAGCCAGGCCGATACCGTCGCGGCGCCGCTGCCGCTGCCGAGTCGGGCGCCGGTAAGCGGCGCCACCAT TGCGAACATCGCCGCGCTCGTCCAGCGTGGCGTGAAGACGGCGTTCCTGCTGCGCGGTGACGCTTTGCAGGAACGGGCCC TGCACGCCGCAGGCAAGATCGCTGCGAAGACGGGTGCCCGCCTGCTTTCCGATACGTTCGCCCCGCGCCTGCAGCGTGGC GCCGGGCGTGTGCCCGTGGAGCGCCTGCCGTACTTCGCCGAGCAAGTCGTGGAATTCCTGGCTGGCACCGAATTGATCGT GCTGGTCGGCGCGCAGCCACCGGTCAGCTTCTTCGCCTACCCGGACAAACCAAGCTGGCTGACGCCGGAAGGATGCCGGC TGGCGGTGCTCTCCCATGCGCACGAGGACGGCACCGGCGCGCTGAAAGCGCTGGCCGACGTGCTCGGCGCAACAGGTTCG ATCGCGGGGCACAGCGTACGCAAGCACATGGAGCCTCCCGCCAGTGGCTCCCTGACCCCCGAATCGATCATGCGCAGCGT GGCCCGGCATCTGCCCGAGCACGCCATCGTCACCGAGGAGTCGGGCATGGCGATGGCGTACTACGGCCTGACCGAATCGG CCGCGCCGCACGATTTCCTGACCCTGTCTGGCGGGGCCATCGGCAGCATGATGGCGCTGTCGATCGGTGCCGGCATCGCC TGCCCGGATCGCAAGATCGTCAACCTGCTTGGCGACGGCAGCGCGATGTACACGGTGCAGTCGCTGTGGACGCAGGCTCG CGAGCAGATCGACGTCGTGAACGTCATCTACGCGAACCGCGGCTACAAGATCCTGAACAACGAACTGAAGCGCGTCGGCG CGTCACAGGACGGTGCACGCGCCGCGTCGATGTTCGATCTGCAAGATCCATCGCTCGACTGGGTGGCACTGGCCGCGGGC ATGGGCGTGGAAGCGGTCCGTACGGTCTCGGCCACGGACTTCGACGCCGCGTTCGCTTCCGCGATGCAGCGCCGCGGGCC GATGCTCATCGAGGCGCTGATCTGA
Upstream 100 bases:
>100_bases TTCTACTATCGATCCGTGCTCGGTTGCACAACCTCGTTGCCCTGCTACGAAACCGCGGTGAACGAGGATTCGATGGTGGT TCGATTTCGGAGTGTCAAGC
Downstream 100 bases:
>100_bases GCGCGATGCACTGGAGCCATTCGCGGGCGGCGAATCGAACCTGCCGATGCGAGCCCCGTATCAGCCCGAATCGGAAGCAG CGATCAACGGCCTCGTTGCC
Product: hypothetical protein
Products: NA
Alternate protein names: ALS; Acetohydroxy-acid synthase large subunit; AHAS [H]
Number of amino acids: Translated: 514; Mature: 514
Protein sequence:
>514_residues MNGAESLLRSLVACGVEVCFGNPGTSEMHFVAALDAVDGMRPVLGLFEGVVTGAADGYGRMAGKPAATLLHLGPGLTNGL ANLHNARRASSPIVNIVGDHAASHSRYEAPLTSDIQGFARPVSQWIHASASALTVGADAARAVQASMEAPGQVATLILPA DTAWSQADTVAAPLPLPSRAPVSGATIANIAALVQRGVKTAFLLRGDALQERALHAAGKIAAKTGARLLSDTFAPRLQRG AGRVPVERLPYFAEQVVEFLAGTELIVLVGAQPPVSFFAYPDKPSWLTPEGCRLAVLSHAHEDGTGALKALADVLGATGS IAGHSVRKHMEPPASGSLTPESIMRSVARHLPEHAIVTEESGMAMAYYGLTESAAPHDFLTLSGGAIGSMMALSIGAGIA CPDRKIVNLLGDGSAMYTVQSLWTQAREQIDVVNVIYANRGYKILNNELKRVGASQDGARAASMFDLQDPSLDWVALAAG MGVEAVRTVSATDFDAAFASAMQRRGPMLIEALI
Sequences:
>Translated_514_residues MNGAESLLRSLVACGVEVCFGNPGTSEMHFVAALDAVDGMRPVLGLFEGVVTGAADGYGRMAGKPAATLLHLGPGLTNGL ANLHNARRASSPIVNIVGDHAASHSRYEAPLTSDIQGFARPVSQWIHASASALTVGADAARAVQASMEAPGQVATLILPA DTAWSQADTVAAPLPLPSRAPVSGATIANIAALVQRGVKTAFLLRGDALQERALHAAGKIAAKTGARLLSDTFAPRLQRG AGRVPVERLPYFAEQVVEFLAGTELIVLVGAQPPVSFFAYPDKPSWLTPEGCRLAVLSHAHEDGTGALKALADVLGATGS IAGHSVRKHMEPPASGSLTPESIMRSVARHLPEHAIVTEESGMAMAYYGLTESAAPHDFLTLSGGAIGSMMALSIGAGIA CPDRKIVNLLGDGSAMYTVQSLWTQAREQIDVVNVIYANRGYKILNNELKRVGASQDGARAASMFDLQDPSLDWVALAAG MGVEAVRTVSATDFDAAFASAMQRRGPMLIEALI >Mature_514_residues MNGAESLLRSLVACGVEVCFGNPGTSEMHFVAALDAVDGMRPVLGLFEGVVTGAADGYGRMAGKPAATLLHLGPGLTNGL ANLHNARRASSPIVNIVGDHAASHSRYEAPLTSDIQGFARPVSQWIHASASALTVGADAARAVQASMEAPGQVATLILPA DTAWSQADTVAAPLPLPSRAPVSGATIANIAALVQRGVKTAFLLRGDALQERALHAAGKIAAKTGARLLSDTFAPRLQRG AGRVPVERLPYFAEQVVEFLAGTELIVLVGAQPPVSFFAYPDKPSWLTPEGCRLAVLSHAHEDGTGALKALADVLGATGS IAGHSVRKHMEPPASGSLTPESIMRSVARHLPEHAIVTEESGMAMAYYGLTESAAPHDFLTLSGGAIGSMMALSIGAGIA CPDRKIVNLLGDGSAMYTVQSLWTQAREQIDVVNVIYANRGYKILNNELKRVGASQDGARAASMFDLQDPSLDWVALAAG MGVEAVRTVSATDFDAAFASAMQRRGPMLIEALI
Specific function: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine [H]
COG id: COG0028
COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the TPP enzyme family [H]
Homologues:
Organism=Escherichia coli, GI1790104, Length=556, Percent_Identity=24.4604316546763, Blast_Score=96, Evalue=6e-21, Organism=Escherichia coli, GI87081685, Length=122, Percent_Identity=36.0655737704918, Blast_Score=68, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012001 - InterPro: IPR011766 [H]
Pfam domain/function: PF02775 TPP_enzyme_C; PF02776 TPP_enzyme_N [H]
EC number: =2.2.1.6 [H]
Molecular weight: Translated: 53458; Mature: 53458
Theoretical pI: Translated: 6.51; Mature: 6.51
Prosite motif: PS00187 TPP_ENZYMES
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNGAESLLRSLVACGVEVCFGNPGTSEMHFVAALDAVDGMRPVLGLFEGVVTGAADGYGR CCHHHHHHHHHHHCCEEEEECCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCC MAGKPAATLLHLGPGLTNGLANLHNARRASSPIVNIVGDHAASHSRYEAPLTSDIQGFAR CCCCCHHHHEECCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH PVSQWIHASASALTVGADAARAVQASMEAPGQVATLILPADTAWSQADTVAAPLPLPSRA HHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC PVSGATIANIAALVQRGVKTAFLLRGDALQERALHAAGKIAAKTGARLLSDTFAPRLQRG CCCCHHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC AGRVPVERLPYFAEQVVEFLAGTELIVLVGAQPPVSFFAYPDKPSWLTPEGCRLAVLSHA CCCCCHHHCCHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEECCC HEDGTGALKALADVLGATGSIAGHSVRKHMEPPASGSLTPESIMRSVARHLPEHAIVTEE CCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECC SGMAMAYYGLTESAAPHDFLTLSGGAIGSMMALSIGAGIACPDRKIVNLLGDGSAMYTVQ CCCEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHH SLWTQAREQIDVVNVIYANRGYKILNNELKRVGASQDGARAASMFDLQDPSLDWVALAAG HHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHEECCCCCCCCHHHHHHC MGVEAVRTVSATDFDAAFASAMQRRGPMLIEALI CCHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCC >Mature Secondary Structure MNGAESLLRSLVACGVEVCFGNPGTSEMHFVAALDAVDGMRPVLGLFEGVVTGAADGYGR CCHHHHHHHHHHHCCEEEEECCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCC MAGKPAATLLHLGPGLTNGLANLHNARRASSPIVNIVGDHAASHSRYEAPLTSDIQGFAR CCCCCHHHHEECCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH PVSQWIHASASALTVGADAARAVQASMEAPGQVATLILPADTAWSQADTVAAPLPLPSRA HHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCC PVSGATIANIAALVQRGVKTAFLLRGDALQERALHAAGKIAAKTGARLLSDTFAPRLQRG CCCCHHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC AGRVPVERLPYFAEQVVEFLAGTELIVLVGAQPPVSFFAYPDKPSWLTPEGCRLAVLSHA CCCCCHHHCCHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEECCC HEDGTGALKALADVLGATGSIAGHSVRKHMEPPASGSLTPESIMRSVARHLPEHAIVTEE CCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECC SGMAMAYYGLTESAAPHDFLTLSGGAIGSMMALSIGAGIACPDRKIVNLLGDGSAMYTVQ CCCEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHH SLWTQAREQIDVVNVIYANRGYKILNNELKRVGASQDGARAASMFDLQDPSLDWVALAAG HHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCCCCCCHHHHEECCCCCCCCHHHHHHC MGVEAVRTVSATDFDAAFASAMQRRGPMLIEALI CCHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230 [H]