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The map label for this gene is surA [C]

Identifier: 94310806

GI number: 94310806

Start: 2024787

End: 2025581

Strand: Direct

Name: surA [C]

Synonym: Rmet_1868

Alternate gene names: 94310806

Gene position: 2024787-2025581 (Clockwise)

Preceding gene: 94310805

Following gene: 94310807

Centisome position: 51.55

GC content: 61.51

Gene sequence:

>795_bases
ATGAAGACCTCCGTCCTCTCGTTCAGCCTGGCGGCTGTGCTTGCTGCTGGCAGCCTGCCCGCATTCGCCCAGAACGCTGC
CGTTGTGAATGGCAAGCCGATTTCGTCGGCCAAGGTGGACAAGCTGATCGCCAGCACTGGCCAGCCGGAAACTCCCGAAC
TGCGCGACCGTGCGCGCAACATGCTGATCGACCGCGAACTGCTGCTCCAGGAAGCCAACAAGCGCGGCATCACCCAGCGT
GACGACGTGCAGGAGCAACTGGAACAGGCCCGCCTGAACGTGCTGGCCGGCGCGGTATTCGAGGACTACGTGCGCACCCA
CGGCGCCAGCGATGAAGAGCTGCGCAAGCAATACGAGAAGATCAAGGCGCAGTTCGGCAACGGCAAGGAATACCACGTCC
GTCACATCCTCGTGGAGAAGGAAGCCGACGCCAAAGCACTGATCGCCAAGATCAAGGCCGGCGCCAAGTTCGAAGATGTG
GCCAAGGCCCAGTCGAAGGACACCGGCTCCGCCGCGAACGGTGGCGACCTGGATTGGGCCAACAGCAGCAGCTACGTGCC
CGAGTTCTCGGCCGCGATGACCAACCTGAAGAAGGGCCAGATGACCGATACGCCGGTCAAGACCCAGTTTGGCTGGCACA
TCATCGAACTGGTGGACACGCGCGACGCCAAGATCCCGTCGTTCGAAGAAGTGAAGCCGCAGCTTCAGCAGATGATGATG
GGCGATCAGGGCTGGCAGCGCGAGCAGTTCCAGGCGATGATGAAGTCCCTCAAGGACAAGGCGAAGATTCAGTAA

Upstream 100 bases:

>100_bases
TCGCAAATCCACGCGTTGGCTGTCAACGCGTACACCGACCAAGAATATCAATCACGCGAAGCAACCCGCGACGCTACTCG
CAACTCTCAGACCTGACCCC

Downstream 100 bases:

>100_bases
TCTGTTGCCAATCCGATAAAAAGCCGGCGCTAATGCGCCGGCTTTTTCATTTAGAGCACTCTGGGCAGCCTTGCACGGCA
CGTGTTTGATCTTGATACGG

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKTSVLSFSLAAVLAAGSLPAFAQNAAVVNGKPISSAKVDKLIASTGQPETPELRDRARNMLIDRELLLQEANKRGITQR
DDVQEQLEQARLNVLAGAVFEDYVRTHGASDEELRKQYEKIKAQFGNGKEYHVRHILVEKEADAKALIAKIKAGAKFEDV
AKAQSKDTGSAANGGDLDWANSSSYVPEFSAAMTNLKKGQMTDTPVKTQFGWHIIELVDTRDAKIPSFEEVKPQLQQMMM
GDQGWQREQFQAMMKSLKDKAKIQ

Sequences:

>Translated_264_residues
MKTSVLSFSLAAVLAAGSLPAFAQNAAVVNGKPISSAKVDKLIASTGQPETPELRDRARNMLIDRELLLQEANKRGITQR
DDVQEQLEQARLNVLAGAVFEDYVRTHGASDEELRKQYEKIKAQFGNGKEYHVRHILVEKEADAKALIAKIKAGAKFEDV
AKAQSKDTGSAANGGDLDWANSSSYVPEFSAAMTNLKKGQMTDTPVKTQFGWHIIELVDTRDAKIPSFEEVKPQLQQMMM
GDQGWQREQFQAMMKSLKDKAKIQ
>Mature_264_residues
MKTSVLSFSLAAVLAAGSLPAFAQNAAVVNGKPISSAKVDKLIASTGQPETPELRDRARNMLIDRELLLQEANKRGITQR
DDVQEQLEQARLNVLAGAVFEDYVRTHGASDEELRKQYEKIKAQFGNGKEYHVRHILVEKEADAKALIAKIKAGAKFEDV
AKAQSKDTGSAANGGDLDWANSSSYVPEFSAAMTNLKKGQMTDTPVKTQFGWHIIELVDTRDAKIPSFEEVKPQLQQMMM
GDQGWQREQFQAMMKSLKDKAKIQ

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=101, Percent_Identity=40.5940594059406, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786238, Length=103, Percent_Identity=45.6310679611651, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786645, Length=168, Percent_Identity=27.9761904761905, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17537235, Length=95, Percent_Identity=44.2105263157895, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21356303, Length=94, Percent_Identity=40.4255319148936, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 29223; Mature: 29223

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSVLSFSLAAVLAAGSLPAFAQNAAVVNGKPISSAKVDKLIASTGQPETPELRDRARN
CCCCHHHHHHHHHHHHCCCCHHHCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
MLIDRELLLQEANKRGITQRDDVQEQLEQARLNVLAGAVFEDYVRTHGASDEELRKQYEK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IKAQFGNGKEYHVRHILVEKEADAKALIAKIKAGAKFEDVAKAQSKDTGSAANGGDLDWA
HHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCC
NSSSYVPEFSAAMTNLKKGQMTDTPVKTQFGWHIIELVDTRDAKIPSFEEVKPQLQQMMM
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
GDQGWQREQFQAMMKSLKDKAKIQ
CCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTSVLSFSLAAVLAAGSLPAFAQNAAVVNGKPISSAKVDKLIASTGQPETPELRDRARN
CCCCHHHHHHHHHHHHCCCCHHHCCCEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
MLIDRELLLQEANKRGITQRDDVQEQLEQARLNVLAGAVFEDYVRTHGASDEELRKQYEK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IKAQFGNGKEYHVRHILVEKEADAKALIAKIKAGAKFEDVAKAQSKDTGSAANGGDLDWA
HHHHCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCC
NSSSYVPEFSAAMTNLKKGQMTDTPVKTQFGWHIIELVDTRDAKIPSFEEVKPQLQQMMM
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
GDQGWQREQFQAMMKSLKDKAKIQ
CCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]