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The map label for this gene is pepM [H]

Identifier: 94310746

GI number: 94310746

Start: 1959433

End: 1961127

Strand: Direct

Name: pepM [H]

Synonym: Rmet_1808

Alternate gene names: 94310746

Gene position: 1959433-1961127 (Clockwise)

Preceding gene: 94310745

Following gene: 94310747

Centisome position: 49.88

GC content: 66.61

Gene sequence:

>1695_bases
ATGAACGCCCACGACCCGAACCTCCTCGCCACCTCGCGCAGCGCCCGCCTGCGCCAGATGCTGCGCTCGAACGAACTCGA
ATTCATCATGGAAGCCCATAACGGCCTGTCCGCGCGCATCGTGCGCGAGGCCGGCTTCAAGGGCATCTGGGCCTCGGGCC
TGGCCATCTCCGCCCAGTTCGGCGTGCGCGACAACAACGAGGCAAGCTGGACCCAGGTGGTCGACAACCTCGAATTCATG
GCCGATGCCAGCGATCTGCCGATCCTGCTGGACGGCGACACCGGCTACGGCAACTTCAACAACGTGCGCCGCCTGGTGCG
CAAGCTCGAGCAGCGCGGCATCGCCGGCGTCTGCATCGAAGACAAGATCTTCCCGAAGACCAACAGCTTCATCGGCGGCG
AGCAGCAGCCGCTGGCCGATATCGACGAGTTCTGCGGCAAGATCAAGGCCGGTAAGGATTCGCAGGCCGACGACGACTTC
TCGATCGTCGCGCGTGTCGAAGCGCTGATCGCCGGCTGGGGCATGGAAGAAGCCCTGCGCCGCGCCGAGGCGTACCGTCA
GGCCGGCGCCGACGCCATCCTGATCCACAGCAAGCTGTCGAAGGCCGACGAGATCGTGACCTTCGCGCGCGAATGGGCCG
GGCGCGCGCCGCTGGTGATCGTTCCCACCAAGTACTACAGCACGCCGACCGACGTGTTCCGCAAGGCCGGCATCAGCCTC
GTGATCTGGGCCAACCACCTGATCCGCGTGGCCGCATCGTCGATGCAGGCTGTGGCCCGGGAAATCCACGACAGCCAGAC
GCTGGTCAACGTGGAAGACCGCATCGCCACCGTCAACGAAATTTTCCGCCTGCAGGATGCCGACGAATACTCGGCCGCCG
AGAAGATCTACCTGACCGGTGGCCAGGCGCCCAGCTCCGCCGTGGTGCTTGCGGCCGGACGCGGCAAGGGCCTGGAGGCC
CTGACCGAAGACAAGCCCAAGATCATGCTGCCGGTAGCCGGCAAGCCGCTGCTGCGCTGGCTGGTCGACGGCTTCAAGAA
CCAGGGCATCAACGACATCACCGTGGTGGGCGGCTACAAGGCCGAGGCGATCGACGCGGCCGGCATCAAGCTGGTGCGCA
ACGAGCGCCACGCCGCCACCGGCGAGCTGGCTTCGCTGGCGTGCGCCGCCGATTCGCTCGAGACCGACACCGTCGTCTCC
TATGGCGACCTGATGTTCCGCAGCTACATCCTGCGCGACCTGCTGGAAACCGATGCGCCGTTCAGCGTGGTGGTCGACTC
ATCCGAGTCCGCCCCGTCGAACCAGAGCGTGCGCGATTTCGCGTGGTGCTCGGCCGCCGACGACCGCGACCTGTTCGGCC
AGAAGGTGCTGCTGCGCAAGATCTCCGACACGCCGGCCGCTACCGACGGAGAGCCGCATGGCCGCTGGATCGGTCTGCTC
AACGTGCGGGGCGAAGGCCGCGCGCGCCTGCAGAAGCTGCTGGCCGAACTGCGTCAGCGGCCCGACTTCGACTCGCTCGA
CATGCCCGACCTGATCAACGCGCTGGTCGAAGCCGGCGAGAAGGTCGAGGTCCGTTACGTACATGGCCACTGGCGCGGCG
TGAACGACCTGGAGGACTTCCGCCGGGCCGGAGACTTCGCGCACACGCAAACGCCGTACGCGCTGGGCAACAACGACGGA
GAGACTGCCCGATGA

Upstream 100 bases:

>100_bases
ACGTCACCGGCGCGCCCTGGATCGAGATCGATTTCCCGGGCGATGTGGCCCGTGCCGCCGAAGAAGTCCTGCCCCAACTG
CAGCCCGTAGGAATCGCCCA

Downstream 100 bases:

>100_bases
TCGAGGCCGTCCAGTTCGTGGAAGCCGCGCGCGAGCGCGGTTTCGAGTGGTACGCGGGCGTACCGTGCTCGTACCTGACG
CCGTTCATCAATTACGTGGT

Product: phosphoenolpyruvate phosphomutase

Products: NA

Alternate protein names: PEP mutase; PEP phosphomutase; Phosphoenolpyruvate mutase [H]

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MNAHDPNLLATSRSARLRQMLRSNELEFIMEAHNGLSARIVREAGFKGIWASGLAISAQFGVRDNNEASWTQVVDNLEFM
ADASDLPILLDGDTGYGNFNNVRRLVRKLEQRGIAGVCIEDKIFPKTNSFIGGEQQPLADIDEFCGKIKAGKDSQADDDF
SIVARVEALIAGWGMEEALRRAEAYRQAGADAILIHSKLSKADEIVTFAREWAGRAPLVIVPTKYYSTPTDVFRKAGISL
VIWANHLIRVAASSMQAVAREIHDSQTLVNVEDRIATVNEIFRLQDADEYSAAEKIYLTGGQAPSSAVVLAAGRGKGLEA
LTEDKPKIMLPVAGKPLLRWLVDGFKNQGINDITVVGGYKAEAIDAAGIKLVRNERHAATGELASLACAADSLETDTVVS
YGDLMFRSYILRDLLETDAPFSVVVDSSESAPSNQSVRDFAWCSAADDRDLFGQKVLLRKISDTPAATDGEPHGRWIGLL
NVRGEGRARLQKLLAELRQRPDFDSLDMPDLINALVEAGEKVEVRYVHGHWRGVNDLEDFRRAGDFAHTQTPYALGNNDG
ETAR

Sequences:

>Translated_564_residues
MNAHDPNLLATSRSARLRQMLRSNELEFIMEAHNGLSARIVREAGFKGIWASGLAISAQFGVRDNNEASWTQVVDNLEFM
ADASDLPILLDGDTGYGNFNNVRRLVRKLEQRGIAGVCIEDKIFPKTNSFIGGEQQPLADIDEFCGKIKAGKDSQADDDF
SIVARVEALIAGWGMEEALRRAEAYRQAGADAILIHSKLSKADEIVTFAREWAGRAPLVIVPTKYYSTPTDVFRKAGISL
VIWANHLIRVAASSMQAVAREIHDSQTLVNVEDRIATVNEIFRLQDADEYSAAEKIYLTGGQAPSSAVVLAAGRGKGLEA
LTEDKPKIMLPVAGKPLLRWLVDGFKNQGINDITVVGGYKAEAIDAAGIKLVRNERHAATGELASLACAADSLETDTVVS
YGDLMFRSYILRDLLETDAPFSVVVDSSESAPSNQSVRDFAWCSAADDRDLFGQKVLLRKISDTPAATDGEPHGRWIGLL
NVRGEGRARLQKLLAELRQRPDFDSLDMPDLINALVEAGEKVEVRYVHGHWRGVNDLEDFRRAGDFAHTQTPYALGNNDG
ETAR
>Mature_564_residues
MNAHDPNLLATSRSARLRQMLRSNELEFIMEAHNGLSARIVREAGFKGIWASGLAISAQFGVRDNNEASWTQVVDNLEFM
ADASDLPILLDGDTGYGNFNNVRRLVRKLEQRGIAGVCIEDKIFPKTNSFIGGEQQPLADIDEFCGKIKAGKDSQADDDF
SIVARVEALIAGWGMEEALRRAEAYRQAGADAILIHSKLSKADEIVTFAREWAGRAPLVIVPTKYYSTPTDVFRKAGISL
VIWANHLIRVAASSMQAVAREIHDSQTLVNVEDRIATVNEIFRLQDADEYSAAEKIYLTGGQAPSSAVVLAAGRGKGLEA
LTEDKPKIMLPVAGKPLLRWLVDGFKNQGINDITVVGGYKAEAIDAAGIKLVRNERHAATGELASLACAADSLETDTVVS
YGDLMFRSYILRDLLETDAPFSVVVDSSESAPSNQSVRDFAWCSAADDRDLFGQKVLLRKISDTPAATDGEPHGRWIGLL
NVRGEGRARLQKLLAELRQRPDFDSLDMPDLINALVEAGEKVEVRYVHGHWRGVNDLEDFRRAGDFAHTQTPYALGNNDG
ETAR

Specific function: Formation of a carbon-phosphorus bond by converting phosphoenolpyruvate (PEP) to phosphonopyruvate (P-Pyr) [H]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate lyase/PEP mutase superfamily. PEP mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786525, Length=284, Percent_Identity=27.112676056338, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012698
- InterPro:   IPR015813 [H]

Pfam domain/function: NA

EC number: =5.4.2.9 [H]

Molecular weight: Translated: 61809; Mature: 61809

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAHDPNLLATSRSARLRQMLRSNELEFIMEAHNGLSARIVREAGFKGIWASGLAISAQF
CCCCCCCCEECCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHCCCCCEEECCEEEEEEE
GVRDNNEASWTQVVDNLEFMADASDLPILLDGDTGYGNFNNVRRLVRKLEQRGIAGVCIE
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEC
DKIFPKTNSFIGGEQQPLADIDEFCGKIKAGKDSQADDDFSIVARVEALIAGWGMEEALR
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHH
RAEAYRQAGADAILIHSKLSKADEIVTFAREWAGRAPLVIVPTKYYSTPTDVFRKAGISL
HHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHCCCEE
VIWANHLIRVAASSMQAVAREIHDSQTLVNVEDRIATVNEIFRLQDADEYSAAEKIYLTG
EEHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCHHCCCCEEEEEC
GQAPSSAVVLAAGRGKGLEALTEDKPKIMLPVAGKPLLRWLVDGFKNQGINDITVVGGYK
CCCCCCEEEEEECCCCCCHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCC
AEAIDAAGIKLVRNERHAATGELASLACAADSLETDTVVSYGDLMFRSYILRDLLETDAP
CCHHHHCCHHEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
FSVVVDSSESAPSNQSVRDFAWCSAADDRDLFGQKVLLRKISDTPAATDGEPHGRWIGLL
EEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
NVRGEGRARLQKLLAELRQRPDFDSLDMPDLINALVEAGEKVEVRYVHGHWRGVNDLEDF
EECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHH
RRAGDFAHTQTPYALGNNDGETAR
HHHCCCCCCCCCCEECCCCCCCCC
>Mature Secondary Structure
MNAHDPNLLATSRSARLRQMLRSNELEFIMEAHNGLSARIVREAGFKGIWASGLAISAQF
CCCCCCCCEECCHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHCCCCCEEECCEEEEEEE
GVRDNNEASWTQVVDNLEFMADASDLPILLDGDTGYGNFNNVRRLVRKLEQRGIAGVCIE
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEC
DKIFPKTNSFIGGEQQPLADIDEFCGKIKAGKDSQADDDFSIVARVEALIAGWGMEEALR
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHH
RAEAYRQAGADAILIHSKLSKADEIVTFAREWAGRAPLVIVPTKYYSTPTDVFRKAGISL
HHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHCCCEE
VIWANHLIRVAASSMQAVAREIHDSQTLVNVEDRIATVNEIFRLQDADEYSAAEKIYLTG
EEHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCHHCCCCEEEEEC
GQAPSSAVVLAAGRGKGLEALTEDKPKIMLPVAGKPLLRWLVDGFKNQGINDITVVGGYK
CCCCCCEEEEEECCCCCCHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCC
AEAIDAAGIKLVRNERHAATGELASLACAADSLETDTVVSYGDLMFRSYILRDLLETDAP
CCHHHHCCHHEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
FSVVVDSSESAPSNQSVRDFAWCSAADDRDLFGQKVLLRKISDTPAATDGEPHGRWIGLL
EEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
NVRGEGRARLQKLLAELRQRPDFDSLDMPDLINALVEAGEKVEVRYVHGHWRGVNDLEDF
EECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHH
RRAGDFAHTQTPYALGNNDGETAR
HHHCCCCCCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9673017 [H]