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The map label for this gene is macB [H]

Identifier: 94310732

GI number: 94310732

Start: 1946109

End: 1947275

Strand: Direct

Name: macB [H]

Synonym: Rmet_1794

Alternate gene names: 94310732

Gene position: 1946109-1947275 (Clockwise)

Preceding gene: 94310731

Following gene: 94310734

Centisome position: 49.54

GC content: 63.67

Gene sequence:

>1167_bases
ATGGTCATCCCGCTCCACTACATCGCACGCAACGTCTGGGCACGGCGCCTGACCACCACGCTGACCGCAGGCGGGCTGGC
GCTGGTCGTGTTCGTATTCGCGACCATGCTGATGCTCGACGCCGGCCTCAAGCGGACGCTGGTGACGACTGGGGAACGTG
ACAACGTCGTGCTGATCCGCAAGGGCGCCGAAACCGAGATACAGAGCGCGATATCGCGCGATCAGGCGGCGGCCATGGAG
ATGCATTCGGCCGTTGCGTTGACCCCGGAAGGCAGGCCGATGTCATCACGCGAGGCCGTGGTGCTGATCTCGCTGACCAA
GACCGGCTACACCACGCCTTCCAATGTGGTGATTCGCGGCATTACCCCGCTGGGGGTGGAGATGCGGCCGCAGGTCAGGC
TGACCCGGGGACGCATGTTCAAGCCGGGCTCGTCGGAAATCATTGTCGGGAGCAGCATCGCCAAGGGTTATGACAACGTC
AGCATCGGCGACCATCTGCGATTTGCCCAGCGGGACTGGACCGTGGTTGGCCACTTCGACGCCGGCGGCAGCGGGTTCGA
TTCCGAGATCTGGGGCGACGTGGACCAGTTGATGCAGTCGTTCCGGCGCACCAGCTATTCCTCTATGGCGGTCCGGTTGG
CCGACTCGGACGCGTTCGATCGTTTTCGCGCCGATATCGACGTCGACCCGCGTCTGGCTAATGAAGCCAAGCGCGAGCAG
CAGTTCTACAGCGACCAGTCGAAGGCGCTATCGGCGTTCATCAACATCCTGGGGCTGACGCTGACCACGATCTTCTCGGT
CGCCGCGATGATCGGCGCGATGATCACCATGTATGCGTCGGTGGCGAACCGCGTTGGCGAGATCGGCACCCTGCGCGCGC
TGGGCTTCCAGCGCATCAACGTGCTCGCGGCCTTCCTGATCGAGGCCGTGCTGCTCGGCCTGGTTGGTGGGGTCGCCGGT
CTGCTCTGCGCCTCGCTGATGCAATTCGCGTCGTTCTCGACCACGAACTTTCAGACCTTCGCCGATCTGTCGTTCCGCTT
CGTGCTGACACCCGGGATCGTGATCAAAACACTGCTGTTCTCGATGACGATGGGCCTGATCGGCGGCTTCCTGCCGGCGC
TCAGGGCGTCGCGGCTGAATATCGTGGATGCGCTGCGGGCGCGTTGA

Upstream 100 bases:

>100_bases
CGTGCGCACTGGTGGTCGGCCTCGCGGCCGCCATCGTCCCCGCGGTGCAGGCGGCGCGCGTGCGCATCGTCGAGGGCCTG
CGGGCCATCGGGTAATTCGG

Downstream 100 bases:

>100_bases
GCCGACCCGCTGCCTTCTCCCGCTGTCTTCCCGCCTGCTTTCTCCCCCTTACCCCATCACCTCCTCGCAAACCTCCAGCC
ACGCCCGCGCGGCGTGCGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MVIPLHYIARNVWARRLTTTLTAGGLALVVFVFATMLMLDAGLKRTLVTTGERDNVVLIRKGAETEIQSAISRDQAAAME
MHSAVALTPEGRPMSSREAVVLISLTKTGYTTPSNVVIRGITPLGVEMRPQVRLTRGRMFKPGSSEIIVGSSIAKGYDNV
SIGDHLRFAQRDWTVVGHFDAGGSGFDSEIWGDVDQLMQSFRRTSYSSMAVRLADSDAFDRFRADIDVDPRLANEAKREQ
QFYSDQSKALSAFINILGLTLTTIFSVAAMIGAMITMYASVANRVGEIGTLRALGFQRINVLAAFLIEAVLLGLVGGVAG
LLCASLMQFASFSTTNFQTFADLSFRFVLTPGIVIKTLLFSMTMGLIGGFLPALRASRLNIVDALRAR

Sequences:

>Translated_388_residues
MVIPLHYIARNVWARRLTTTLTAGGLALVVFVFATMLMLDAGLKRTLVTTGERDNVVLIRKGAETEIQSAISRDQAAAME
MHSAVALTPEGRPMSSREAVVLISLTKTGYTTPSNVVIRGITPLGVEMRPQVRLTRGRMFKPGSSEIIVGSSIAKGYDNV
SIGDHLRFAQRDWTVVGHFDAGGSGFDSEIWGDVDQLMQSFRRTSYSSMAVRLADSDAFDRFRADIDVDPRLANEAKREQ
QFYSDQSKALSAFINILGLTLTTIFSVAAMIGAMITMYASVANRVGEIGTLRALGFQRINVLAAFLIEAVLLGLVGGVAG
LLCASLMQFASFSTTNFQTFADLSFRFVLTPGIVIKTLLFSMTMGLIGGFLPALRASRLNIVDALRAR
>Mature_388_residues
MVIPLHYIARNVWARRLTTTLTAGGLALVVFVFATMLMLDAGLKRTLVTTGERDNVVLIRKGAETEIQSAISRDQAAAME
MHSAVALTPEGRPMSSREAVVLISLTKTGYTTPSNVVIRGITPLGVEMRPQVRLTRGRMFKPGSSEIIVGSSIAKGYDNV
SIGDHLRFAQRDWTVVGHFDAGGSGFDSEIWGDVDQLMQSFRRTSYSSMAVRLADSDAFDRFRADIDVDPRLANEAKREQ
QFYSDQSKALSAFINILGLTLTTIFSVAAMIGAMITMYASVANRVGEIGTLRALGFQRINVLAAFLIEAVLLGLVGGVAG
LLCASLMQFASFSTTNFQTFADLSFRFVLTPGIVIKTLLFSMTMGLIGGFLPALRASRLNIVDALRAR

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=128, Percent_Identity=39.0625, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42150; Mature: 42150

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIPLHYIARNVWARRLTTTLTAGGLALVVFVFATMLMLDAGLKRTLVTTGERDNVVLIR
CEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCEEEEE
KGAETEIQSAISRDQAAAMEMHSAVALTPEGRPMSSREAVVLISLTKTGYTTPSNVVIRG
CCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEC
ITPLGVEMRPQVRLTRGRMFKPGSSEIIVGSSIAKGYDNVSIGDHLRFAQRDWTVVGHFD
CCCCCCCCCCCEEECCCCCCCCCCCCEEECCHHHCCCCCCCCCHHHHHHCCCCEEEEEEC
AGGSGFDSEIWGDVDQLMQSFRRTSYSSMAVRLADSDAFDRFRADIDVDPRLANEAKREQ
CCCCCCCHHHHCCHHHHHHHHHHCCHHHHEEEECCCHHHHHHHCCCCCCCHHHHHHHHHH
QFYSDQSKALSAFINILGLTLTTIFSVAAMIGAMITMYASVANRVGEIGTLRALGFQRIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VLAAFLIEAVLLGLVGGVAGLLCASLMQFASFSTTNFQTFADLSFRFVLTPGIVIKTLLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEECCHHHHHHHHH
SMTMGLIGGFLPALRASRLNIVDALRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVIPLHYIARNVWARRLTTTLTAGGLALVVFVFATMLMLDAGLKRTLVTTGERDNVVLIR
CEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCEEEEE
KGAETEIQSAISRDQAAAMEMHSAVALTPEGRPMSSREAVVLISLTKTGYTTPSNVVIRG
CCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEC
ITPLGVEMRPQVRLTRGRMFKPGSSEIIVGSSIAKGYDNVSIGDHLRFAQRDWTVVGHFD
CCCCCCCCCCCEEECCCCCCCCCCCCEEECCHHHCCCCCCCCCHHHHHHCCCCEEEEEEC
AGGSGFDSEIWGDVDQLMQSFRRTSYSSMAVRLADSDAFDRFRADIDVDPRLANEAKREQ
CCCCCCCHHHHCCHHHHHHHHHHCCHHHHEEEECCCHHHHHHHCCCCCCCHHHHHHHHHH
QFYSDQSKALSAFINILGLTLTTIFSVAAMIGAMITMYASVANRVGEIGTLRALGFQRIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VLAAFLIEAVLLGLVGGVAGLLCASLMQFASFSTTNFQTFADLSFRFVLTPGIVIKTLLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEEECCHHHHHHHHH
SMTMGLIGGFLPALRASRLNIVDALRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA