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The map label for this gene is ampC [H]

Identifier: 94310714

GI number: 94310714

Start: 1927745

End: 1928917

Strand: Reverse

Name: ampC [H]

Synonym: Rmet_1776

Alternate gene names: 94310714

Gene position: 1928917-1927745 (Counterclockwise)

Preceding gene: 94310716

Following gene: 94310712

Centisome position: 49.11

GC content: 64.54

Gene sequence:

>1173_bases
ATGAAAATTTTCGCGTCCTACCGCCTTCGAACCGTTACCGCCGCCTTGGCGCTTTGCACGGCCAGCGCCCATGCCGCGGG
TGATGGTGTGCCCGTCGGGGAGGATCGTCTGGCGCGGCTGGTGGCAGATACCGTCCGACCCGTCATGGCGCAGTACGAAG
TACCCGGCATGGCCGTGGCCGTAACAGTCCGCGGCAAGTCCCAGGTCTTCAACTTCGGCCTGGCATCGAAGGCGGACGCC
ACCCCGGTCACCGAACACACGTTGTTCGAGATCGGGTCGGTCAGCAAGACGTTTACGGCGACGCTCGCCTCATACGCGGC
GCAGCGTGGCGCCATATCGTTCTCAGACAAGGCTAGCCAGTACCTGCCCGGATTGGCGGGTAGCAGCCTCGATGCGATCA
GCCTGCTGGAACTCGGGACGTACACGGCAGGCGGGCTGCCGTTGCAGTTCCCCGATGCGGTGACCACCTCTGACCGGATG
CTGGCGTACTTCAAGGAATGGAAGCCGACGTACGCGGCTGGCACGCATCGGCAGTACTCGAACCCGAGCATCGGCCTGTT
CGGTTATCTGGCCGCGCGGAGCCTGGGTGAGCCGTTCGACAACCTGATGGAGCACCGCATCTTTCCGGGCCTGGGCCTGA
AGCACTCATTCATCCGGGTGCCGCAGTCCCGCATGGGCGACTATGCCTATGGCTACAAGGACGGCAAGCCGATCCGCGTG
AACCCCGGCATGTTCGACTCGGAAGCCTATGGCGTGAAGACCACGGCGGCCGACATGATTCGGTTCGTCGAAGCCAATAT
GGATGGCGCGCGGCTGGAGCCGACGTTGCAGCGGGCGGTTACCGGTACGCACACCGGCTACTTCCGCGTTGGCCCCATGA
CCCAAGGCCTGGGCTGGGAAATGTACACCTGGCCAACCTCGCTCGAGGATCTGCTGACGGGCAACGCCGCCGGAATGCTG
GAGCCGAAGGAAGTCGCACGGCTGGCGCCGCCGCAGCCCCCCAGGGCCGACGTGCTGATCAATAAGACTGGTTCCACCAA
CGGCTTCGGCGCCTATGTGGTGTTCGTCCCGGCTCGTCAGATCGGCGTGGTGATGTTGGCGAACCGCAATCTGCCGATCC
CCGAGCGCGTGCGGGCGGCGTACCAGATCCTGAAGGCGCTCGACGCACAGTAG

Upstream 100 bases:

>100_bases
GCATGGGCAGCTTCGGGCAATGGGTCGACGCAAGCCAGCGACCGTGCCATTGTACGAGTTTCCTATACCATTTCACGCCA
TTGATTTTTTTGCCTCCACC

Downstream 100 bases:

>100_bases
ACACCGATATCGGGCATCGGGCATCGGGCATCGGGCATCGGGCATCGGGCATCGGGTCGGGATCAGGCCGGGTCGATGTT
CTGATTCAGCCTGAAAGCGT

Product: beta-lactamase/D-alanine carboxypeptidase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKIFASYRLRTVTAALALCTASAHAAGDGVPVGEDRLARLVADTVRPVMAQYEVPGMAVAVTVRGKSQVFNFGLASKADA
TPVTEHTLFEIGSVSKTFTATLASYAAQRGAISFSDKASQYLPGLAGSSLDAISLLELGTYTAGGLPLQFPDAVTTSDRM
LAYFKEWKPTYAAGTHRQYSNPSIGLFGYLAARSLGEPFDNLMEHRIFPGLGLKHSFIRVPQSRMGDYAYGYKDGKPIRV
NPGMFDSEAYGVKTTAADMIRFVEANMDGARLEPTLQRAVTGTHTGYFRVGPMTQGLGWEMYTWPTSLEDLLTGNAAGML
EPKEVARLAPPQPPRADVLINKTGSTNGFGAYVVFVPARQIGVVMLANRNLPIPERVRAAYQILKALDAQ

Sequences:

>Translated_390_residues
MKIFASYRLRTVTAALALCTASAHAAGDGVPVGEDRLARLVADTVRPVMAQYEVPGMAVAVTVRGKSQVFNFGLASKADA
TPVTEHTLFEIGSVSKTFTATLASYAAQRGAISFSDKASQYLPGLAGSSLDAISLLELGTYTAGGLPLQFPDAVTTSDRM
LAYFKEWKPTYAAGTHRQYSNPSIGLFGYLAARSLGEPFDNLMEHRIFPGLGLKHSFIRVPQSRMGDYAYGYKDGKPIRV
NPGMFDSEAYGVKTTAADMIRFVEANMDGARLEPTLQRAVTGTHTGYFRVGPMTQGLGWEMYTWPTSLEDLLTGNAAGML
EPKEVARLAPPQPPRADVLINKTGSTNGFGAYVVFVPARQIGVVMLANRNLPIPERVRAAYQILKALDAQ
>Mature_390_residues
MKIFASYRLRTVTAALALCTASAHAAGDGVPVGEDRLARLVADTVRPVMAQYEVPGMAVAVTVRGKSQVFNFGLASKADA
TPVTEHTLFEIGSVSKTFTATLASYAAQRGAISFSDKASQYLPGLAGSSLDAISLLELGTYTAGGLPLQFPDAVTTSDRM
LAYFKEWKPTYAAGTHRQYSNPSIGLFGYLAARSLGEPFDNLMEHRIFPGLGLKHSFIRVPQSRMGDYAYGYKDGKPIRV
NPGMFDSEAYGVKTTAADMIRFVEANMDGARLEPTLQRAVTGTHTGYFRVGPMTQGLGWEMYTWPTSLEDLLTGNAAGML
EPKEVARLAPPQPPRADVLINKTGSTNGFGAYVVFVPARQIGVVMLANRNLPIPERVRAAYQILKALDAQ

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=380, Percent_Identity=43.9473684210526, Blast_Score=333, Evalue=1e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 42061; Mature: 42061

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00099 THIOLASE_3 ; PS00336 BETA_LACTAMASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFASYRLRTVTAALALCTASAHAAGDGVPVGEDRLARLVADTVRPVMAQYEVPGMAVA
CEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
VTVRGKSQVFNFGLASKADATPVTEHTLFEIGSVSKTFTATLASYAAQRGAISFSDKASQ
EEECCCHHEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
YLPGLAGSSLDAISLLELGTYTAGGLPLQFPDAVTTSDRMLAYFKEWKPTYAAGTHRQYS
HCCCCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
NPSIGLFGYLAARSLGEPFDNLMEHRIFPGLGLKHSFIRVPQSRMGDYAYGYKDGKPIRV
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHCCCHHHCCCCEECCCCCCEEEE
NPGMFDSEAYGVKTTAADMIRFVEANMDGARLEPTLQRAVTGTHTGYFRVGPMTQGLGWE
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCE
MYTWPTSLEDLLTGNAAGMLEPKEVARLAPPQPPRADVLINKTGSTNGFGAYVVFVPARQ
EEECCCCHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCCCCCCEEEEEEEECCC
IGVVMLANRNLPIPERVRAAYQILKALDAQ
CCEEEEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIFASYRLRTVTAALALCTASAHAAGDGVPVGEDRLARLVADTVRPVMAQYEVPGMAVA
CEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
VTVRGKSQVFNFGLASKADATPVTEHTLFEIGSVSKTFTATLASYAAQRGAISFSDKASQ
EEECCCHHEEECCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
YLPGLAGSSLDAISLLELGTYTAGGLPLQFPDAVTTSDRMLAYFKEWKPTYAAGTHRQYS
HCCCCCCCCCCHHHHHHHCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
NPSIGLFGYLAARSLGEPFDNLMEHRIFPGLGLKHSFIRVPQSRMGDYAYGYKDGKPIRV
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHCCCHHHCCCCEECCCCCCEEEE
NPGMFDSEAYGVKTTAADMIRFVEANMDGARLEPTLQRAVTGTHTGYFRVGPMTQGLGWE
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCCE
MYTWPTSLEDLLTGNAAGMLEPKEVARLAPPQPPRADVLINKTGSTNGFGAYVVFVPARQ
EEECCCCHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCCCCCCEEEEEEEECCC
IGVVMLANRNLPIPERVRAAYQILKALDAQ
CCEEEEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA