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The map label for this gene is agrR [H]

Identifier: 94310689

GI number: 94310689

Start: 1900803

End: 1901477

Strand: Direct

Name: agrR [H]

Synonym: Rmet_1751

Alternate gene names: 94310689

Gene position: 1900803-1901477 (Clockwise)

Preceding gene: 94310684

Following gene: 94310690

Centisome position: 48.39

GC content: 56.89

Gene sequence:

>675_bases
ATGAAGATCTTGGTAATCGAAGATGAACCTAAGACTGGCGAGTACCTCCGAAAAGGCCTCACCGAGTCATCTTTCGTTGT
CGATCTTGCGTCGACAGGACGGGATGGCCTGCACCACGCAATCGACGGGGACTACGATCTGGTCATTCTTGATGTCATGC
TGCCTGGCATGAACGGATGGGAAGTGCTCAAGGAACTCCGGGAACACAAAGATACTCCCGTGCTCTTCCTGACCGCACGC
GATGAAGTCGAGGACAGAGTGAAAGGGCTCGAGCTTGGCGGCGATGACTACCTCGCAAAACCCTTTGCTTTCGTCGAATT
GCTGGCGCGGGCCCGGACGCTGCTGCGGCGCGGACCCACGCGCGAAGCTGAGCGCATCGAAATCGAGGACTTGGAGATCG
ACCTTTTGCGTCACCGAGTCTCCAGAGGAGGGATACGCATCGACTTGTCGCCCAGGGAGTTCGCATTGCTCCACTTCCTC
GCGCGACGACACGGCGAAGTCCTTAGTCGCACGCAAATCGCCTCACACGTTTGGGATATGAACTTCGACAGCGACACGAA
CGTCGTGGACGTGGCGATTCGACGCCTTCGAGCGAAGATGGATGACACTTACGCTCCCAAACTTATCCATAGCGTCCGCG
GCATCGGCTACGTCCTTGAGAACCGACAGTCTTGA

Upstream 100 bases:

>100_bases
GACGAAACGATTACAGTCTTGTCATCCAATAGGCGAACCTGCGCCGTTATCATCGGCGGCATCGTTTGAGCTGTGAGCCC
GTGCAGCTGAGGATGAAAAC

Downstream 100 bases:

>100_bases
TGCGTAAAAGGTCGCTTACCGCTCGGCTCGCACTTGCATTTGCCCTGATCGCCGGACTAACTTTTTCCGGCGTGGGAATC
TATCTGTATGGTTCCCTCGC

Product: DNA-binding response regulator in two-component regulatory system with AgrS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKILVIEDEPKTGEYLRKGLTESSFVVDLASTGRDGLHHAIDGDYDLVILDVMLPGMNGWEVLKELREHKDTPVLFLTAR
DEVEDRVKGLELGGDDYLAKPFAFVELLARARTLLRRGPTREAERIEIEDLEIDLLRHRVSRGGIRIDLSPREFALLHFL
ARRHGEVLSRTQIASHVWDMNFDSDTNVVDVAIRRLRAKMDDTYAPKLIHSVRGIGYVLENRQS

Sequences:

>Translated_224_residues
MKILVIEDEPKTGEYLRKGLTESSFVVDLASTGRDGLHHAIDGDYDLVILDVMLPGMNGWEVLKELREHKDTPVLFLTAR
DEVEDRVKGLELGGDDYLAKPFAFVELLARARTLLRRGPTREAERIEIEDLEIDLLRHRVSRGGIRIDLSPREFALLHFL
ARRHGEVLSRTQIASHVWDMNFDSDTNVVDVAIRRLRAKMDDTYAPKLIHSVRGIGYVLENRQS
>Mature_224_residues
MKILVIEDEPKTGEYLRKGLTESSFVVDLASTGRDGLHHAIDGDYDLVILDVMLPGMNGWEVLKELREHKDTPVLFLTAR
DEVEDRVKGLELGGDDYLAKPFAFVELLARARTLLRRGPTREAERIEIEDLEIDLLRHRVSRGGIRIDLSPREFALLHFL
ARRHGEVLSRTQIASHVWDMNFDSDTNVVDVAIRRLRAKMDDTYAPKLIHSVRGIGYVLENRQS

Specific function: Member of the two-component regulatory system CzcS/CzcR involved in the control of cobalt, zinc and cadmium homeostasis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=60.3603603603604, Blast_Score=278, Evalue=3e-76,
Organism=Escherichia coli, GI87082012, Length=217, Percent_Identity=55.7603686635945, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=40, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=39.1111111111111, Blast_Score=148, Evalue=2e-37,
Organism=Escherichia coli, GI1788394, Length=219, Percent_Identity=38.8127853881278, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=36.3636363636364, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=35.1598173515982, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=38.2882882882883, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=29.5964125560538, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=33.0396475770925, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=35.0877192982456, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=36.5638766519824, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=31.4159292035398, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=28.2608695652174, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=38.3177570093458, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=37.037037037037, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=35.2380952380952, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25595; Mature: 25595

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVIEDEPKTGEYLRKGLTESSFVVDLASTGRDGLHHAIDGDYDLVILDVMLPGMNGW
CEEEEEECCCCHHHHHHHCCCCCCEEEEEHHCCCCCCHHCCCCCCCEEEEEECCCCCCHH
EVLKELREHKDTPVLFLTARDEVEDRVKGLELGGDDYLAKPFAFVELLARARTLLRRGPT
HHHHHHHHCCCCCEEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
REAERIEIEDLEIDLLRHRVSRGGIRIDLSPREFALLHFLARRHGEVLSRTQIASHVWDM
CCCCEEEHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NFDSDTNVVDVAIRRLRAKMDDTYAPKLIHSVRGIGYVLENRQS
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKILVIEDEPKTGEYLRKGLTESSFVVDLASTGRDGLHHAIDGDYDLVILDVMLPGMNGW
CEEEEEECCCCHHHHHHHCCCCCCEEEEEHHCCCCCCHHCCCCCCCEEEEEECCCCCCHH
EVLKELREHKDTPVLFLTARDEVEDRVKGLELGGDDYLAKPFAFVELLARARTLLRRGPT
HHHHHHHHCCCCCEEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
REAERIEIEDLEIDLLRHRVSRGGIRIDLSPREFALLHFLARRHGEVLSRTQIASHVWDM
CCCCEEEHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NFDSDTNVVDVAIRRLRAKMDDTYAPKLIHSVRGIGYVLENRQS
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9044283 [H]