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The map label for this gene is silC [H]

Identifier: 94310650

GI number: 94310650

Start: 1851867

End: 1853426

Strand: Direct

Name: silC [H]

Synonym: Rmet_1710

Alternate gene names: 94310650

Gene position: 1851867-1853426 (Clockwise)

Preceding gene: 94310649

Following gene: 94310651

Centisome position: 47.14

GC content: 65.9

Gene sequence:

>1560_bases
ATGTTGCCCCAGGGCCGCGTGTTCCGTTGCTGGATGCTGGCCGCGACGATGCTCGCCGGCTGCGCGCGCGTTGGCCCGGA
TTTCCAGCCGCAGCACGAGACGTGGAGCGGCCAATGGACCAGCGAGGCGATCGGGCAGGCCAGCGAGGCGGGTGACCAAC
CGGATATGCGCCAATGGTGGCAGGTCTTCAACGACCCGGTGCTCGAACACCTGATCACCGAGGCCGATGCCAATGACGCC
GGGGTTCGGATTGCCGGCCTGCGGGTCATGGAAGCCCGGGCGCAACTTGGCATGGCGCTGGCTGGCCGGTATCCCCAGAT
GCAGCAGGCGGGCGCGGATGCCATGTACGTTCACAGCCGCCAATCCGGGCCAACTGCGCAAACCGCTCGCGTCTGGGAGT
ACAGCGCGGGTGTCGATGTCGGCTGGGAACTCGACTTCTGGGGGAAATTCGCCCGGGCGATCGAGTCCGCCGATGCCGCG
TACTTCGCGGCCCAGGCGAATCACGAGAACGTACTGGTACTGCTTCACGCACAACTCGCGCAGACCTATTACGCATTGCG
CACCGCGGAAGCCCGCGTGCGGATAGCGCGGGAGAACGCCCGACTGCAGAAGCGCAGCTATGAGATCACCGAGCGATTGT
TCAAGGCCGGCGAAAGCGACGAACTGGACCTGCAACAAGCCAAGACGCAGTACTTCGGCACATTGAGCAGCATTCCCGAA
CTGGAGCGGCAGATTGCGCTCTCGCGCAACGCCGTGGCGATCCTGCTGGGGAGGCCACCCGGCCCGATTCCCGAGTTGGG
CGAGGCATCGGGCAAGGAGGGCGTGTTGCCCCGGATCGATCGGGCGATTCTGCAAGACGTGCCCGCCAACCTGTTGCTGC
GCCGACCGGACATCCGGGCCGCCGAGTTCCAGATCGCGGCGCAGTCGGCCCAGATCGGCGTGGCGAAGGCGGACCTGTAT
CCATCGGTGACGCTCGTCGGCAGCATCGGCTGGTCCGCGACTTCGCTGCCCGGGACGCAGAACGGCCTGCTGCTGGTGGG
CGGCCCCAGCCTTCGCTGGAACATCTTCGACTATGGCCGGATCCACAACAACGTGCGCGTGCAGGATGCCCGGCTCCAGC
AACTGATCCTCACCTACCAGAACGACGTGCGCGTGGCGGCGCGCGAGGCCGACGATGCGGCCAGCGGCCTGCTCAAGGCA
CTCGAACGCGAAGAAATCCTGCGTGAGGCCGCGTATTCTGCGGAACGCTCGCTGACGCTGGCCAACACCCTGTTCAAGGA
GGGGTACTCCGACTTCCAGCGCGTGCTCGATGCCCAGCGGGCGTTGTTCGCCCAGCAGGACGCCTATCTGGTCAATCGCA
GCAACGCCGTTGGCTATCTGATCGACCTTTACAAGGCCCTTGGCGGTGGCTGGTACAGCGAGCAGCCGTTGGTCGACCCA
GCCACCCGCGACCAGATGCGGCAGCGTACCGATTGGGGAGACCTGCTGGACGAGCCGCCGCGCACGCCGCCGACATCCAA
TAACACCACGGCCAAAGCCACCGGGAGCCAACGCCAATGA

Upstream 100 bases:

>100_bases
AGCAAGCCATCGAAGGCGGCGAGGCCGTGGCGAGTGGTGAGGCCGTGGAGGGTGGCCAGGCGTCGGGACGTACCGAAAGC
GGTCCGGCTGCCGGATAGCG

Downstream 100 bases:

>100_bases
GTGACGCCAGTGATGCGAATGCGCCAGCCACGCCGCCTGCCTCGCCAGGCCCGGCGGCATCCGGAGACGCGTCGGGAAAA
GGGGTGCGGTGGGTTGTCAT

Product: outer membrane heavy metal efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MLPQGRVFRCWMLAATMLAGCARVGPDFQPQHETWSGQWTSEAIGQASEAGDQPDMRQWWQVFNDPVLEHLITEADANDA
GVRIAGLRVMEARAQLGMALAGRYPQMQQAGADAMYVHSRQSGPTAQTARVWEYSAGVDVGWELDFWGKFARAIESADAA
YFAAQANHENVLVLLHAQLAQTYYALRTAEARVRIARENARLQKRSYEITERLFKAGESDELDLQQAKTQYFGTLSSIPE
LERQIALSRNAVAILLGRPPGPIPELGEASGKEGVLPRIDRAILQDVPANLLLRRPDIRAAEFQIAAQSAQIGVAKADLY
PSVTLVGSIGWSATSLPGTQNGLLLVGGPSLRWNIFDYGRIHNNVRVQDARLQQLILTYQNDVRVAAREADDAASGLLKA
LEREEILREAAYSAERSLTLANTLFKEGYSDFQRVLDAQRALFAQQDAYLVNRSNAVGYLIDLYKALGGGWYSEQPLVDP
ATRDQMRQRTDWGDLLDEPPRTPPTSNNTTAKATGSQRQ

Sequences:

>Translated_519_residues
MLPQGRVFRCWMLAATMLAGCARVGPDFQPQHETWSGQWTSEAIGQASEAGDQPDMRQWWQVFNDPVLEHLITEADANDA
GVRIAGLRVMEARAQLGMALAGRYPQMQQAGADAMYVHSRQSGPTAQTARVWEYSAGVDVGWELDFWGKFARAIESADAA
YFAAQANHENVLVLLHAQLAQTYYALRTAEARVRIARENARLQKRSYEITERLFKAGESDELDLQQAKTQYFGTLSSIPE
LERQIALSRNAVAILLGRPPGPIPELGEASGKEGVLPRIDRAILQDVPANLLLRRPDIRAAEFQIAAQSAQIGVAKADLY
PSVTLVGSIGWSATSLPGTQNGLLLVGGPSLRWNIFDYGRIHNNVRVQDARLQQLILTYQNDVRVAAREADDAASGLLKA
LEREEILREAAYSAERSLTLANTLFKEGYSDFQRVLDAQRALFAQQDAYLVNRSNAVGYLIDLYKALGGGWYSEQPLVDP
ATRDQMRQRTDWGDLLDEPPRTPPTSNNTTAKATGSQRQ
>Mature_519_residues
MLPQGRVFRCWMLAATMLAGCARVGPDFQPQHETWSGQWTSEAIGQASEAGDQPDMRQWWQVFNDPVLEHLITEADANDA
GVRIAGLRVMEARAQLGMALAGRYPQMQQAGADAMYVHSRQSGPTAQTARVWEYSAGVDVGWELDFWGKFARAIESADAA
YFAAQANHENVLVLLHAQLAQTYYALRTAEARVRIARENARLQKRSYEITERLFKAGESDELDLQQAKTQYFGTLSSIPE
LERQIALSRNAVAILLGRPPGPIPELGEASGKEGVLPRIDRAILQDVPANLLLRRPDIRAAEFQIAAQSAQIGVAKADLY
PSVTLVGSIGWSATSLPGTQNGLLLVGGPSLRWNIFDYGRIHNNVRVQDARLQQLILTYQNDVRVAAREADDAASGLLKA
LEREEILREAAYSAERSLTLANTLFKEGYSDFQRVLDAQRALFAQQDAYLVNRSNAVGYLIDLYKALGGGWYSEQPLVDP
ATRDQMRQRTDWGDLLDEPPRTPPTSNNTTAKATGSQRQ

Specific function: Component of the sil cation-efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=484, Percent_Identity=30.9917355371901, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI2367348, Length=490, Percent_Identity=24.0816326530612, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 57438; Mature: 57438

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPQGRVFRCWMLAATMLAGCARVGPDFQPQHETWSGQWTSEAIGQASEAGDQPDMRQWW
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHCCCCCCHHHHH
QVFNDPVLEHLITEADANDAGVRIAGLRVMEARAQLGMALAGRYPQMQQAGADAMYVHSR
HHHCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECC
QSGPTAQTARVWEYSAGVDVGWELDFWGKFARAIESADAAYFAAQANHENVLVLLHAQLA
CCCCCCHHHEEEEECCCCCCCEEEHHHHHHHHHHHHCCHHEEEEECCCCCEEEEEEHHHH
QTYYALRTAEARVRIARENARLQKRSYEITERLFKAGESDELDLQQAKTQYFGTLSSIPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LERQIALSRNAVAILLGRPPGPIPELGEASGKEGVLPRIDRAILQDVPANLLLRRPDIRA
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHEEECCCCCH
AEFQIAAQSAQIGVAKADLYPSVTLVGSIGWSATSLPGTQNGLLLVGGPSLRWNIFDYGR
HHHEEEHHHHHCCEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCEEEEEEECCC
IHNNVRVQDARLQQLILTYQNDVRVAAREADDAASGLLKALEREEILREAAYSAERSLTL
CCCCEEEHHHHHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ANTLFKEGYSDFQRVLDAQRALFAQQDAYLVNRSNAVGYLIDLYKALGGGWYSEQPLVDP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
ATRDQMRQRTDWGDLLDEPPRTPPTSNNTTAKATGSQRQ
HHHHHHHHHCCHHHHHCCCCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MLPQGRVFRCWMLAATMLAGCARVGPDFQPQHETWSGQWTSEAIGQASEAGDQPDMRQWW
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHCCCCCCHHHHH
QVFNDPVLEHLITEADANDAGVRIAGLRVMEARAQLGMALAGRYPQMQQAGADAMYVHSR
HHHCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECC
QSGPTAQTARVWEYSAGVDVGWELDFWGKFARAIESADAAYFAAQANHENVLVLLHAQLA
CCCCCCHHHEEEEECCCCCCCEEEHHHHHHHHHHHHCCHHEEEEECCCCCEEEEEEHHHH
QTYYALRTAEARVRIARENARLQKRSYEITERLFKAGESDELDLQQAKTQYFGTLSSIPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LERQIALSRNAVAILLGRPPGPIPELGEASGKEGVLPRIDRAILQDVPANLLLRRPDIRA
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHEEECCCCCH
AEFQIAAQSAQIGVAKADLYPSVTLVGSIGWSATSLPGTQNGLLLVGGPSLRWNIFDYGR
HHHEEEHHHHHCCEEECCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCEEEEEEECCC
IHNNVRVQDARLQQLILTYQNDVRVAAREADDAASGLLKALEREEILREAAYSAERSLTL
CCCCEEEHHHHHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ANTLFKEGYSDFQRVLDAQRALFAQQDAYLVNRSNAVGYLIDLYKALGGGWYSEQPLVDP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCC
ATRDQMRQRTDWGDLLDEPPRTPPTSNNTTAKATGSQRQ
HHHHHHHHHCCHHHHHCCCCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]