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The map label for this gene is nodV [H]

Identifier: 94310637

GI number: 94310637

Start: 1839378

End: 1840331

Strand: Direct

Name: nodV [H]

Synonym: Rmet_1697

Alternate gene names: 94310637

Gene position: 1839378-1840331 (Clockwise)

Preceding gene: 94310636

Following gene: 94310638

Centisome position: 46.83

GC content: 62.89

Gene sequence:

>954_bases
ATGCGATGGCTGTCCTTCCTGTTGGTAGGCATCTCCAGCGGCGTGGCGTTCGCCGCCGCGATCGTTCCCAGCTTCGGGCG
TCGCAGGTCGCATTCCGGCGGGACAACGGAATCAGTGCAATCCAGCAACCATGCAAGGGAGATCGCCCATCTGTCGCCCG
CACCCGGCATGAACGAACTAGCCGGCTCGATCGCGCATGAATTGAACCAGCCGCTGACGGCTATCACCAGCAATGCTCAG
GCGGCCAGGGAGTATCTGGCATCGGGGCCATGCGACCCCGCCGAGGTGCGCGAGATCCTGGACGATATCGTCGCCGATGC
GTCTCGCGCGAGCGAGATCGTCAGGCGGGTGAGGGCATTGATCCTGGGCGAAGCCCCTTCGGCGATCCACTTCAATGTCG
GCGAGGTCGTCGATCAGGCGATAGCCCTCGTCGATGCCAATGCGCGGGCACGTAGTGTTCTGGTGTCGCGCGAAGTTGCC
AATTCGCTTCCCCGCGCCGTTGGCGACCCGATGGAAATCCAGCTGGTGCTGCTCAATCTGCTGAGCAACGCCCTCGATGC
AGTGGAATCCGTGCGCCCGCACGGCGAGCGCTCAGCGTCGATCCTGGCGCAGGAACGCAATGGAATGGTCGTCGTTTCGG
TGCGCGACAACGGTTGCGGCGTCGAACCGGGGCAGCTCGAGCGTATCTTCCAGCCGTTCTATTCGTCGAAGCACAAGGGC
ATGGGGTTGGGGCTGTCTTTCAGCCGCGCCCTGGTGGAGCGCAATGGCGGACGCCTGTCTGCGATCCGCAACAGCAACAC
GGGTATGACTTTTGAACTATCGCTGCGCACGGAAGACGCGGCGCAGGACCTGCGCGGGTCGGTATTGCCACTCGCACCGC
GCGGCATCCATCCGCTCCATCACGGAGGAAAGAACGATGAACGCAATGCAGCCAACGGTATGTATCGTCGATGA

Upstream 100 bases:

>100_bases
GAAACTCTCGCGTGTCCGCGCTCGGGCCAATGCCCGCAGTGGCCGTCATTTGCGGCAATGCAGCAAGTCTCATTCACTCC
ACCGCTGAAGGACAACAGCA

Downstream 100 bases:

>100_bases
CGACGACAGTGTGCGGCGTGCCCTGGCACGCGTCCTTGGCGCCCATCGGTATCACACCAGTTGCTTCGATTCCGCCAAGC
GCTTTCTGGATAACGTCGAA

Product: putative Histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MRWLSFLLVGISSGVAFAAAIVPSFGRRRSHSGGTTESVQSSNHAREIAHLSPAPGMNELAGSIAHELNQPLTAITSNAQ
AAREYLASGPCDPAEVREILDDIVADASRASEIVRRVRALILGEAPSAIHFNVGEVVDQAIALVDANARARSVLVSREVA
NSLPRAVGDPMEIQLVLLNLLSNALDAVESVRPHGERSASILAQERNGMVVVSVRDNGCGVEPGQLERIFQPFYSSKHKG
MGLGLSFSRALVERNGGRLSAIRNSNTGMTFELSLRTEDAAQDLRGSVLPLAPRGIHPLHHGGKNDERNAANGMYRR

Sequences:

>Translated_317_residues
MRWLSFLLVGISSGVAFAAAIVPSFGRRRSHSGGTTESVQSSNHAREIAHLSPAPGMNELAGSIAHELNQPLTAITSNAQ
AAREYLASGPCDPAEVREILDDIVADASRASEIVRRVRALILGEAPSAIHFNVGEVVDQAIALVDANARARSVLVSREVA
NSLPRAVGDPMEIQLVLLNLLSNALDAVESVRPHGERSASILAQERNGMVVVSVRDNGCGVEPGQLERIFQPFYSSKHKG
MGLGLSFSRALVERNGGRLSAIRNSNTGMTFELSLRTEDAAQDLRGSVLPLAPRGIHPLHHGGKNDERNAANGMYRR
>Mature_317_residues
MRWLSFLLVGISSGVAFAAAIVPSFGRRRSHSGGTTESVQSSNHAREIAHLSPAPGMNELAGSIAHELNQPLTAITSNAQ
AAREYLASGPCDPAEVREILDDIVADASRASEIVRRVRALILGEAPSAIHFNVGEVVDQAIALVDANARARSVLVSREVA
NSLPRAVGDPMEIQLVLLNLLSNALDAVESVRPHGERSASILAQERNGMVVVSVRDNGCGVEPGQLERIFQPFYSSKHKG
MGLGLSFSRALVERNGGRLSAIRNSNTGMTFELSLRTEDAAQDLRGSVLPLAPRGIHPLHHGGKNDERNAANGMYRR

Specific function: Member of the two-component regulatory system nodV/nodW probably involved in the regulation of the transcription of genes involved in the nodulation process. NodV may function as a membrane-associated protein kinase that phosphorylates nodW in response to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=27.8260869565217, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=25.8964143426295, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87081816, Length=227, Percent_Identity=31.2775330396476, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=26.8085106382979, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=24.6808510638298, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 33896; Mature: 33896

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLSFLLVGISSGVAFAAAIVPSFGRRRSHSGGTTESVQSSNHAREIAHLSPAPGMNEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
AGSIAHELNQPLTAITSNAQAAREYLASGPCDPAEVREILDDIVADASRASEIVRRVRAL
HHHHHHHHCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILGEAPSAIHFNVGEVVDQAIALVDANARARSVLVSREVANSLPRAVGDPMEIQLVLLNL
HHCCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LSNALDAVESVRPHGERSASILAQERNGMVVVSVRDNGCGVEPGQLERIFQPFYSSKHKG
HHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCC
MGLGLSFSRALVERNGGRLSAIRNSNTGMTFELSLRTEDAAQDLRGSVLPLAPRGIHPLH
CCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCCCHHH
HGGKNDERNAANGMYRR
CCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MRWLSFLLVGISSGVAFAAAIVPSFGRRRSHSGGTTESVQSSNHAREIAHLSPAPGMNEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
AGSIAHELNQPLTAITSNAQAAREYLASGPCDPAEVREILDDIVADASRASEIVRRVRAL
HHHHHHHHCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILGEAPSAIHFNVGEVVDQAIALVDANARARSVLVSREVANSLPRAVGDPMEIQLVLLNL
HHCCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LSNALDAVESVRPHGERSASILAQERNGMVVVSVRDNGCGVEPGQLERIFQPFYSSKHKG
HHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCC
MGLGLSFSRALVERNGGRLSAIRNSNTGMTFELSLRTEDAAQDLRGSVLPLAPRGIHPLH
CCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCCCHHH
HGGKNDERNAANGMYRR
CCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2320582; 11157954; 12597275 [H]