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The map label for this gene is quiP [H]

Identifier: 94310520

GI number: 94310520

Start: 1698626

End: 1701091

Strand: Direct

Name: quiP [H]

Synonym: Rmet_1578

Alternate gene names: 94310520

Gene position: 1698626-1701091 (Clockwise)

Preceding gene: 94310519

Following gene: 94310521

Centisome position: 43.24

GC content: 66.26

Gene sequence:

>2466_bases
ATGCGCTGGTTGAAACGGCTGGGCTGGGGTTTGCTGGGCATCGTGCTGTTGGCGGCAACCGGGTCGATCGGCGGCTATAT
CTGGTACCGGCAGGCGTCGCAGCCAGACGTGGCCGGCACCTTGCGACTGGCCGGCCTGCGAGACCGCGTGGTGGTGGTGC
GAGACCGGAATGCCGTGCCGCATATTCAGGCGGCCAACTCACTCGACGCCTACTACGCGCTTGGCTACGTCCACGCGCAG
GACCGCCTATGGCAGATGCAAATGAACAAGCGCATCGTCGCGGGCCGTCTTGCCGAAATCCTGGGTCCCAGCGCGCTCGA
AACCGACCGCTTCCTGCGCACACTGGGCGTGCGGCGCAATGCAGAGGCGATCCTCGCACAGACACCGCCAGAGGGCCGCG
CGGTGCTGCAGGCCTATGCCGACGGCGTCAATGCGTTCATCGACACGCGCAAGTCGGCGCTGCCACCGGAATTCCTGATC
GTTGGCACCCGCCCCGAGCACTGGGAGCCGGTGGATACGATTGGCTGGCAGACGATGATGGCGTGGGATCTCGGGGGCAA
CTGGACGCAGGAAGTCCTGCGCATGGGGCTGTCCCAGCAGTTGCCGGCCTCTCGCATTGCAGAAATCCTGGCGCCGTATC
CGGGCGAGAAGCCGTTGCGGACGATGGACTACGCCAGCTTCTATCGCAAGCTTGGCCCGGTGGCCACGGCCATGGCGCAA
GTTGTCCAGCAGGCGCCGTCTGGCTACGTGGAGGGGATGGGCTCGAACAACTGGGTTGTCTCCGGCGCCCATACGCGCAG
TGGCAAGCCTCTGCTGGCCAATGACCCGCATCTGGGGCTCCAGGCGCCCGCGCTCTGGTATTTCGCGCATCTGCAGGCCC
CTGGCCTGGATCTGACCGGCGCCACGCTGCCCGGCGCGCCGCTGGTGGTGCTGGGTCACAACAAGCGCATTGCCTGGGGC
TTCACCAATACCGCGCCCGATGTCCAGGACCTGTATCTGGAGCGGGTCGACCCGGCCAATCCCAACCGCTATCAAACGCC
AGAGGGCTGGGCGGAGTTCAGCACGCGAACCGAGACCATCCAGGTCAAGGGGGCGCCGGATGTCACGCTGACGGTGCGCG
GCACGCGCCACGGACCGGTCATGTCCGATGTGGCGGAGCCGATCAGCGCGGCCGCCAAGCCGCTGGGCGCGCAGTACGTG
GTGGCGTTCCAGTGGGCGGCGCTGCGCGCCGACGATCGCACGTTCGTGGCCAGCCTGAACATGAGCCACGCATCGGACTG
GAAGTCGTTCGTGGCGGCATTGCGTGACTTTCATTCGCCGCAGCAGAACATCGTCTATGCCGACGTCGACGGCAATATCG
GATATATCGCCCCGGGCCGCGTGCCGCTGCGCCGCCCTGACAATGACCTGATGGGGCTCGCGCCAGCGCCGGGCTGGGAT
GCGCGTTACGACTGGCAGGGTTTCATTCCGTTCGAGCAGTTGCCGCGCCGCTTCAATCCGCCCGAGGGCATGATCGTCAC
GGCGAACCAGAAGATCGTGGGCGACGATTACCCGTACTTCATCACGAGCGAGTGGACGGTGCCGTATCGCTACCAGCGCA
TCCGCACGCTGCTGGAGGCCGAGCCGCACCATACGAAGGACACCTTCGCCGCGATCCAGAAGGACGTGGTCTCTCTAGCC
GTGCGCGATGCGCTGCCATTGCTGCTGGCTGCCCCAGTGGCGACGGACGCCACACGCCCGCCGCGCGAGCGCGCGCTGCT
CGACGCGCTGCGCAAATGGGACGGCACGATGTCGGCCGACCGGGCGGAGCCGCTGGTGGTGACCGCATGGCTACGCGAAC
TGTCGCGCCTGCTGTTCGAGGACAAGGTCGGCGAATCGCAATTCAACCGACTCTGGGAGCAACGCAACGTCCAGTTGCCG
ATGCTCAATGCGATGCGCGACCCGAAGGGCCTGGGTGCCTTCTGGTGCGACAACTCGCGCACGCCCGCCCACGAGAGCTG
CGCGGACACGATCGGGCTGGCCTGGCAGCGGGCGATTGCCGATCTGGATCGTCGCTACGGCGAAGACACGGCCAAGTGGC
GTTGGGGCAAGGCGCACACCGCTCGTTCCGAGCACAAGCCGTTTGGCAAGGTGCCGTACCTGTCCGGCCTGTTCAACGTG
CGCGTGCCCACCGGCGGCGATACGTATACGGTGGATGTGGGCCGCCACAACCTCCGCGATGAGCACGCACCATTCGAGAG
CACGCACGCGGCCAGTCTGCGCGCCATATACGATCTGGACGACCTGTCGGAGTCGCGTTTCATGACGTCGACCGGACAGT
CTGGCAATGCGCTGTCGCCGCACTACCGCGACTGGACCGAGGAGTGGGCAGCCGTGCAGTTCATCACGATTGGCGCCCAC
CGGCGCAATCCGGGCGGTGACAGCTTTGACACGCTGGTACTGCGGCCGCTGAGTGATGGCAACTGA

Upstream 100 bases:

>100_bases
CCCGCCTGACCGAGGACGAGTTCGTCGTATCATCAATGCCCGGCATGTCCGGGCATTTTTTATTCCTGTCATTGCAGTCT
TTCCTATCGGGGGGAGTTGG

Downstream 100 bases:

>100_bases
TCGACGGCAACCGAGCGATGGCAACTGACCCGCCCGATGTTGTCAAAGATTGTGTCAATGGAAATCATTCCCGGTAAGCG
GGCAGTACCATCACGGGACC

Product: penicillin amidase or acylase

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Quorum signal utilization and inactivation protein; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 821; Mature: 821

Protein sequence:

>821_residues
MRWLKRLGWGLLGIVLLAATGSIGGYIWYRQASQPDVAGTLRLAGLRDRVVVVRDRNAVPHIQAANSLDAYYALGYVHAQ
DRLWQMQMNKRIVAGRLAEILGPSALETDRFLRTLGVRRNAEAILAQTPPEGRAVLQAYADGVNAFIDTRKSALPPEFLI
VGTRPEHWEPVDTIGWQTMMAWDLGGNWTQEVLRMGLSQQLPASRIAEILAPYPGEKPLRTMDYASFYRKLGPVATAMAQ
VVQQAPSGYVEGMGSNNWVVSGAHTRSGKPLLANDPHLGLQAPALWYFAHLQAPGLDLTGATLPGAPLVVLGHNKRIAWG
FTNTAPDVQDLYLERVDPANPNRYQTPEGWAEFSTRTETIQVKGAPDVTLTVRGTRHGPVMSDVAEPISAAAKPLGAQYV
VAFQWAALRADDRTFVASLNMSHASDWKSFVAALRDFHSPQQNIVYADVDGNIGYIAPGRVPLRRPDNDLMGLAPAPGWD
ARYDWQGFIPFEQLPRRFNPPEGMIVTANQKIVGDDYPYFITSEWTVPYRYQRIRTLLEAEPHHTKDTFAAIQKDVVSLA
VRDALPLLLAAPVATDATRPPRERALLDALRKWDGTMSADRAEPLVVTAWLRELSRLLFEDKVGESQFNRLWEQRNVQLP
MLNAMRDPKGLGAFWCDNSRTPAHESCADTIGLAWQRAIADLDRRYGEDTAKWRWGKAHTARSEHKPFGKVPYLSGLFNV
RVPTGGDTYTVDVGRHNLRDEHAPFESTHAASLRAIYDLDDLSESRFMTSTGQSGNALSPHYRDWTEEWAAVQFITIGAH
RRNPGGDSFDTLVLRPLSDGN

Sequences:

>Translated_821_residues
MRWLKRLGWGLLGIVLLAATGSIGGYIWYRQASQPDVAGTLRLAGLRDRVVVVRDRNAVPHIQAANSLDAYYALGYVHAQ
DRLWQMQMNKRIVAGRLAEILGPSALETDRFLRTLGVRRNAEAILAQTPPEGRAVLQAYADGVNAFIDTRKSALPPEFLI
VGTRPEHWEPVDTIGWQTMMAWDLGGNWTQEVLRMGLSQQLPASRIAEILAPYPGEKPLRTMDYASFYRKLGPVATAMAQ
VVQQAPSGYVEGMGSNNWVVSGAHTRSGKPLLANDPHLGLQAPALWYFAHLQAPGLDLTGATLPGAPLVVLGHNKRIAWG
FTNTAPDVQDLYLERVDPANPNRYQTPEGWAEFSTRTETIQVKGAPDVTLTVRGTRHGPVMSDVAEPISAAAKPLGAQYV
VAFQWAALRADDRTFVASLNMSHASDWKSFVAALRDFHSPQQNIVYADVDGNIGYIAPGRVPLRRPDNDLMGLAPAPGWD
ARYDWQGFIPFEQLPRRFNPPEGMIVTANQKIVGDDYPYFITSEWTVPYRYQRIRTLLEAEPHHTKDTFAAIQKDVVSLA
VRDALPLLLAAPVATDATRPPRERALLDALRKWDGTMSADRAEPLVVTAWLRELSRLLFEDKVGESQFNRLWEQRNVQLP
MLNAMRDPKGLGAFWCDNSRTPAHESCADTIGLAWQRAIADLDRRYGEDTAKWRWGKAHTARSEHKPFGKVPYLSGLFNV
RVPTGGDTYTVDVGRHNLRDEHAPFESTHAASLRAIYDLDDLSESRFMTSTGQSGNALSPHYRDWTEEWAAVQFITIGAH
RRNPGGDSFDTLVLRPLSDGN
>Mature_821_residues
MRWLKRLGWGLLGIVLLAATGSIGGYIWYRQASQPDVAGTLRLAGLRDRVVVVRDRNAVPHIQAANSLDAYYALGYVHAQ
DRLWQMQMNKRIVAGRLAEILGPSALETDRFLRTLGVRRNAEAILAQTPPEGRAVLQAYADGVNAFIDTRKSALPPEFLI
VGTRPEHWEPVDTIGWQTMMAWDLGGNWTQEVLRMGLSQQLPASRIAEILAPYPGEKPLRTMDYASFYRKLGPVATAMAQ
VVQQAPSGYVEGMGSNNWVVSGAHTRSGKPLLANDPHLGLQAPALWYFAHLQAPGLDLTGATLPGAPLVVLGHNKRIAWG
FTNTAPDVQDLYLERVDPANPNRYQTPEGWAEFSTRTETIQVKGAPDVTLTVRGTRHGPVMSDVAEPISAAAKPLGAQYV
VAFQWAALRADDRTFVASLNMSHASDWKSFVAALRDFHSPQQNIVYADVDGNIGYIAPGRVPLRRPDNDLMGLAPAPGWD
ARYDWQGFIPFEQLPRRFNPPEGMIVTANQKIVGDDYPYFITSEWTVPYRYQRIRTLLEAEPHHTKDTFAAIQKDVVSLA
VRDALPLLLAAPVATDATRPPRERALLDALRKWDGTMSADRAEPLVVTAWLRELSRLLFEDKVGESQFNRLWEQRNVQLP
MLNAMRDPKGLGAFWCDNSRTPAHESCADTIGLAWQRAIADLDRRYGEDTAKWRWGKAHTARSEHKPFGKVPYLSGLFNV
RVPTGGDTYTVDVGRHNLRDEHAPFESTHAASLRAIYDLDDLSESRFMTSTGQSGNALSPHYRDWTEEWAAVQFITIGAH
RRNPGGDSFDTLVLRPLSDGN

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 91347; Mature: 91347

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLKRLGWGLLGIVLLAATGSIGGYIWYRQASQPDVAGTLRLAGLRDRVVVVRDRNAVP
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEECCCCCC
HIQAANSLDAYYALGYVHAQDRLWQMQMNKRIVAGRLAEILGPSALETDRFLRTLGVRRN
CEECCCCCCHHHHEEEEEHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
AEAILAQTPPEGRAVLQAYADGVNAFIDTRKSALPPEFLIVGTRPEHWEPVDTIGWQTMM
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHCCCEEEE
AWDLGGNWTQEVLRMGLSQQLPASRIAEILAPYPGEKPLRTMDYASFYRKLGPVATAMAQ
EEECCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VVQQAPSGYVEGMGSNNWVVSGAHTRSGKPLLANDPHLGLQAPALWYFAHLQAPGLDLTG
HHHHCCCCCEECCCCCCEEEECCCCCCCCCEECCCCCCCCCCCHHHHEEHHCCCCCCCCC
ATLPGAPLVVLGHNKRIAWGFTNTAPDVQDLYLERVDPANPNRYQTPEGWAEFSTRTETI
CCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCEEE
QVKGAPDVTLTVRGTRHGPVMSDVAEPISAAAKPLGAQYVVAFQWAALRADDRTFVASLN
EEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEHCCCCCCEEEEEEC
MSHASDWKSFVAALRDFHSPQQNIVYADVDGNIGYIAPGRVPLRRPDNDLMGLAPAPGWD
CCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCEECCCCCCCC
ARYDWQGFIPFEQLPRRFNPPEGMIVTANQKIVGDDYPYFITSEWTVPYRYQRIRTLLEA
CCCCCCCCCCHHHHHCCCCCCCCEEEECCCEEECCCCCEEEEECCCCCHHHHHHHHHHHC
EPHHTKDTFAAIQKDVVSLAVRDALPLLLAAPVATDATRPPRERALLDALRKWDGTMSAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
RAEPLVVTAWLRELSRLLFEDKVGESQFNRLWEQRNVQLPMLNAMRDPKGLGAFWCDNSR
CCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCCC
TPAHESCADTIGLAWQRAIADLDRRYGEDTAKWRWGKAHTARSEHKPFGKVPYLSGLFNV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCCCCCCCCCCCHHCCEEEE
RVPTGGDTYTVDVGRHNLRDEHAPFESTHAASLRAIYDLDDLSESRFMTSTGQSGNALSP
EECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHEEECHHHCCCCCEEECCCCCCCCCCC
HYRDWTEEWAAVQFITIGAHRRNPGGDSFDTLVLRPLSDGN
CHHHHHHHHHEEEEEEEECCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MRWLKRLGWGLLGIVLLAATGSIGGYIWYRQASQPDVAGTLRLAGLRDRVVVVRDRNAVP
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEECCCCCC
HIQAANSLDAYYALGYVHAQDRLWQMQMNKRIVAGRLAEILGPSALETDRFLRTLGVRRN
CEECCCCCCHHHHEEEEEHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
AEAILAQTPPEGRAVLQAYADGVNAFIDTRKSALPPEFLIVGTRPEHWEPVDTIGWQTMM
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHCCCEEEE
AWDLGGNWTQEVLRMGLSQQLPASRIAEILAPYPGEKPLRTMDYASFYRKLGPVATAMAQ
EEECCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VVQQAPSGYVEGMGSNNWVVSGAHTRSGKPLLANDPHLGLQAPALWYFAHLQAPGLDLTG
HHHHCCCCCEECCCCCCEEEECCCCCCCCCEECCCCCCCCCCCHHHHEEHHCCCCCCCCC
ATLPGAPLVVLGHNKRIAWGFTNTAPDVQDLYLERVDPANPNRYQTPEGWAEFSTRTETI
CCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCEEE
QVKGAPDVTLTVRGTRHGPVMSDVAEPISAAAKPLGAQYVVAFQWAALRADDRTFVASLN
EEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEHCCCCCCEEEEEEC
MSHASDWKSFVAALRDFHSPQQNIVYADVDGNIGYIAPGRVPLRRPDNDLMGLAPAPGWD
CCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCEECCCCCCCC
ARYDWQGFIPFEQLPRRFNPPEGMIVTANQKIVGDDYPYFITSEWTVPYRYQRIRTLLEA
CCCCCCCCCCHHHHHCCCCCCCCEEEECCCEEECCCCCEEEEECCCCCHHHHHHHHHHHC
EPHHTKDTFAAIQKDVVSLAVRDALPLLLAAPVATDATRPPRERALLDALRKWDGTMSAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
RAEPLVVTAWLRELSRLLFEDKVGESQFNRLWEQRNVQLPMLNAMRDPKGLGAFWCDNSR
CCCCEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCCC
TPAHESCADTIGLAWQRAIADLDRRYGEDTAKWRWGKAHTARSEHKPFGKVPYLSGLFNV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCCCCCCCCCCCHHCCEEEE
RVPTGGDTYTVDVGRHNLRDEHAPFESTHAASLRAIYDLDDLSESRFMTSTGQSGNALSP
EECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHEEECHHHCCCCCEEECCCCCCCCCCC
HYRDWTEEWAAVQFITIGAHRRNPGGDSFDTLVLRPLSDGN
CHHHHHHHHHEEEEEEEECCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]