Click here to switch to the map view.

The map label for this gene is cbbT1 [H]

Identifier: 94310455

GI number: 94310455

Start: 1634055

End: 1636109

Strand: Direct

Name: cbbT1 [H]

Synonym: Rmet_1513

Alternate gene names: 94310455

Gene position: 1634055-1636109 (Clockwise)

Preceding gene: 94310454

Following gene: 94310456

Centisome position: 41.6

GC content: 69.78

Gene sequence:

>2055_bases
ATGGCCAGTACCTCTGCCGACCGCGTGCTGCGCCCCGAGAGCGGCCGCTACGACGAACTCGCCAACGCGCTGCGCGCCCT
GGCCATGGACGCCGTTCAGCAGGCCAACTCCGGCCACCCCGGCGCGCCGATGGGCATGGCCGAGATGGCCGTCGCGCTGT
GGAGCGGTCATCTGCGCCACAACCCGGGCAATCCCGGGTGGCCCGACCGCGACCGGTTCGTCTTGTCCAACGGGCATGCG
TCGATGCTGCTGTATGCCTTGCTGCACCTGAGCGGCTACGACCTGCCGATCGAGGAACTGCAGCGCTTCCGGCAACTGCA
CAGCAAGACCCCGGGCCACCCCGAGGTGGGCCTCACGCCCGGCGTGGAAACCACGACCGGCCCATTGGGCCAAGGTTTGG
CGAACGCGGTCGGCATGGCGCTGGCCGGGAAGTTGCTGGGCGACGAGTTCAACCGCCCGGGACATGTCGTGGTCGACCAC
CACACCTACGTCTTTCTCGGCGACGGCTGCCTGATGGAAGGCATCAGTCACGAGGTCTGCTCGCTGGCTGGCGTGTGGAG
GCTCAACAAGCTGATCGCGCTGTACGACGACAACGGCATCTCGATCGACGGTGCGGTCGATGCCTGGTTTCGCGACGACA
CCGCGGCACGCTTTCGAGCCTATGGCTGGAACGTGATCGGCCCGATCGACGGCCACGACGTCGTGGCGATCGGGCGTTCC
ATCGCCGACGCGCGGCGCTCTGCCGACCGGCCCACGTTGATCGTGTGCCGCACCACCATCGGCCGCGGCTCCCCGGGACG
CGCCGGTACGGCCAAGGCCCATGGCGAACCGCTCGGGGCCGACGAGATTGCCGCCACGCGCGCCGCCATCGGGTGGCACG
AGGCTCCGTTCGAAATTCCGGATACCGTGCGTGCGCGCTGGAGCGCGCGCGATCTGGGCGCCAGGCGCGAAGCTCAGTGG
CGCTTGGGCTTCGAGGCCTACCGGAGCGAATATCCCGCACTGGCCGCGGAGTTCGAGCGCCGGATTGCCGGCGACCTGCC
GTCGTCGTTTCATGAAGCCGCGTCGGCAGCGATGATCGAACTCGGTCAGGCCACCACGCCGGTCGCCTCACGCAAGGCTT
CGCAGCAAGCGCTGGCGATGCTGGCGCCCAAGATCCCCGAGATGCTCGGCGGCAGTGCCGACCTCACGGGCTCTAACCTG
ACCGACTTCCCGGGCTGCGGTGCCGTGCGGGCCGGCCAGCCCGGCGGGCGCCACGTCAACTACGGCGTGCGCGAGTTCGG
CATGGCGGCGATCATGAACGGGCTGGCGCTGCACGGCGGCTTCATTCCGTACGGCGGCACCTTCCTCACCTTCAGCGACT
ACAGCCGCAACGGAATTCGCATGGCCGCGCTGATGAAGCTGCGCGTGGTTCATGTCTTCACGCACGACTCGATCGGCCTG
GGCGAGGACGGCCCGACGCACCAGGCCGTCGAGCATGCCGCGAGCTTGCGCCTGATCCCCAATCTCGATGTCTGGCGGCC
CTGCGACGCCGCCGAGACCGCGGTGGCCTGGGCGTTCGCGCTCGAGCAACGCACGCGCCCCAGCGCGTTGCTGCTGTCGC
GGCAGAACCTGCCGCCGCAGGCGCGCACTGCGGAGCAGGTCGCGCAGATCCGTCGCGGCGGTTACGTGCTCTCCGACCGA
CCCGAGCCGCAGGTGGTGCTGATCGGCACCGGCTCCGAGGTGTCCATCGCGATGGAGGCGCAGCGCCTTCTCGATGCGGT
GGGCATCGCGGCGCGGGTGGTCTCGTTGCCCTGCAGCACCCTCTTCGATCGGCAGGAGGCCGCCTGGCACGAGCAGGTGC
TCGGCCGGGGAATCCCGCGCATCGGCGTCGAAGCGGGCGTCACCTCGTGGTGGGGCCAGTACCACTGCGTCGCCGCGCTG
GGGGTGAACAGCTTCGGCGAGTCGGCGCCCGGCCCGCAGGTGTACGAGCACTTCGGCCTCGACGCCAAGGCGCTGGCCGA
CCTGGCACGCGAAGTGCTGGCGCGCGAAGTGCGGTTCGTCCGGTCCAGGAGCTGA

Upstream 100 bases:

>100_bases
TCGTGCCCGGCGGCAAGATGGAGCTGGCGATGCAGTTGATTTTTACGCCGTTTATCTGGCGCATGATGGAACGGCGCAAG
CGCGCCCTGGGAGTCCTGTG

Downstream 100 bases:

>100_bases
CATGCGCTACGACATCGTCAGTTTCGATCTCGACGGCACGCTGGTGGACACGGCCGCCGAGATTGCCGAGGCCGCCAATC
GCGCGCTCGAGTCGCATGGG

Product: transketolase 1, thiamin-binding protein

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MASTSADRVLRPESGRYDELANALRALAMDAVQQANSGHPGAPMGMAEMAVALWSGHLRHNPGNPGWPDRDRFVLSNGHA
SMLLYALLHLSGYDLPIEELQRFRQLHSKTPGHPEVGLTPGVETTTGPLGQGLANAVGMALAGKLLGDEFNRPGHVVVDH
HTYVFLGDGCLMEGISHEVCSLAGVWRLNKLIALYDDNGISIDGAVDAWFRDDTAARFRAYGWNVIGPIDGHDVVAIGRS
IADARRSADRPTLIVCRTTIGRGSPGRAGTAKAHGEPLGADEIAATRAAIGWHEAPFEIPDTVRARWSARDLGARREAQW
RLGFEAYRSEYPALAAEFERRIAGDLPSSFHEAASAAMIELGQATTPVASRKASQQALAMLAPKIPEMLGGSADLTGSNL
TDFPGCGAVRAGQPGGRHVNYGVREFGMAAIMNGLALHGGFIPYGGTFLTFSDYSRNGIRMAALMKLRVVHVFTHDSIGL
GEDGPTHQAVEHAASLRLIPNLDVWRPCDAAETAVAWAFALEQRTRPSALLLSRQNLPPQARTAEQVAQIRRGGYVLSDR
PEPQVVLIGTGSEVSIAMEAQRLLDAVGIAARVVSLPCSTLFDRQEAAWHEQVLGRGIPRIGVEAGVTSWWGQYHCVAAL
GVNSFGESAPGPQVYEHFGLDAKALADLAREVLAREVRFVRSRS

Sequences:

>Translated_684_residues
MASTSADRVLRPESGRYDELANALRALAMDAVQQANSGHPGAPMGMAEMAVALWSGHLRHNPGNPGWPDRDRFVLSNGHA
SMLLYALLHLSGYDLPIEELQRFRQLHSKTPGHPEVGLTPGVETTTGPLGQGLANAVGMALAGKLLGDEFNRPGHVVVDH
HTYVFLGDGCLMEGISHEVCSLAGVWRLNKLIALYDDNGISIDGAVDAWFRDDTAARFRAYGWNVIGPIDGHDVVAIGRS
IADARRSADRPTLIVCRTTIGRGSPGRAGTAKAHGEPLGADEIAATRAAIGWHEAPFEIPDTVRARWSARDLGARREAQW
RLGFEAYRSEYPALAAEFERRIAGDLPSSFHEAASAAMIELGQATTPVASRKASQQALAMLAPKIPEMLGGSADLTGSNL
TDFPGCGAVRAGQPGGRHVNYGVREFGMAAIMNGLALHGGFIPYGGTFLTFSDYSRNGIRMAALMKLRVVHVFTHDSIGL
GEDGPTHQAVEHAASLRLIPNLDVWRPCDAAETAVAWAFALEQRTRPSALLLSRQNLPPQARTAEQVAQIRRGGYVLSDR
PEPQVVLIGTGSEVSIAMEAQRLLDAVGIAARVVSLPCSTLFDRQEAAWHEQVLGRGIPRIGVEAGVTSWWGQYHCVAAL
GVNSFGESAPGPQVYEHFGLDAKALADLAREVLAREVRFVRSRS
>Mature_683_residues
ASTSADRVLRPESGRYDELANALRALAMDAVQQANSGHPGAPMGMAEMAVALWSGHLRHNPGNPGWPDRDRFVLSNGHAS
MLLYALLHLSGYDLPIEELQRFRQLHSKTPGHPEVGLTPGVETTTGPLGQGLANAVGMALAGKLLGDEFNRPGHVVVDHH
TYVFLGDGCLMEGISHEVCSLAGVWRLNKLIALYDDNGISIDGAVDAWFRDDTAARFRAYGWNVIGPIDGHDVVAIGRSI
ADARRSADRPTLIVCRTTIGRGSPGRAGTAKAHGEPLGADEIAATRAAIGWHEAPFEIPDTVRARWSARDLGARREAQWR
LGFEAYRSEYPALAAEFERRIAGDLPSSFHEAASAAMIELGQATTPVASRKASQQALAMLAPKIPEMLGGSADLTGSNLT
DFPGCGAVRAGQPGGRHVNYGVREFGMAAIMNGLALHGGFIPYGGTFLTFSDYSRNGIRMAALMKLRVVHVFTHDSIGLG
EDGPTHQAVEHAASLRLIPNLDVWRPCDAAETAVAWAFALEQRTRPSALLLSRQNLPPQARTAEQVAQIRRGGYVLSDRP
EPQVVLIGTGSEVSIAMEAQRLLDAVGIAARVVSLPCSTLFDRQEAAWHEQVLGRGIPRIGVEAGVTSWWGQYHCVAALG
VNSFGESAPGPQVYEHFGLDAKALADLAREVLAREVRFVRSRS

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=677, Percent_Identity=26.8833087149188, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI4507521, Length=677, Percent_Identity=26.8833087149188, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI133778974, Length=591, Percent_Identity=27.072758037225, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI225637459, Length=272, Percent_Identity=27.9411764705882, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI225637461, Length=183, Percent_Identity=30.6010928961749, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI225637463, Length=183, Percent_Identity=30.6010928961749, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI48994911, Length=659, Percent_Identity=58.7253414264036, Blast_Score=811, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=659, Percent_Identity=56.4491654021244, Blast_Score=772, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=669, Percent_Identity=25.8594917787743, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6325331, Length=671, Percent_Identity=46.6467958271237, Blast_Score=582, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6319593, Length=668, Percent_Identity=43.8622754491018, Blast_Score=531, Evalue=1e-152,
Organism=Drosophila melanogaster, GI45551847, Length=674, Percent_Identity=26.4094955489614, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI45550715, Length=674, Percent_Identity=26.4094955489614, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24666278, Length=579, Percent_Identity=27.8065630397237, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24645119, Length=635, Percent_Identity=25.8267716535433, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 73483; Mature: 73352

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTSADRVLRPESGRYDELANALRALAMDAVQQANSGHPGAPMGMAEMAVALWSGHLRH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
NPGNPGWPDRDRFVLSNGHASMLLYALLHLSGYDLPIEELQRFRQLHSKTPGHPEVGLTP
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GVETTTGPLGQGLANAVGMALAGKLLGDEFNRPGHVVVDHHTYVFLGDGCLMEGISHEVC
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEECCCHHHHHHHHHHH
SLAGVWRLNKLIALYDDNGISIDGAVDAWFRDDTAARFRAYGWNVIGPIDGHDVVAIGRS
HHHHHHHHCCEEEEECCCCEEECCCHHHHHCCCHHHHHHHCCCCEECCCCCCCHHHHHHH
IADARRSADRPTLIVCRTTIGRGSPGRAGTAKAHGEPLGADEIAATRAAIGWHEAPFEIP
HHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
DTVRARWSARDLGARREAQWRLGFEAYRSEYPALAAEFERRIAGDLPSSFHEAASAAMIE
HHHHHHHCHHHHCCCCCHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LGQATTPVASRKASQQALAMLAPKIPEMLGGSADLTGSNLTDFPGCGAVRAGQPGGRHVN
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YGVREFGMAAIMNGLALHGGFIPYGGTFLTFSDYSRNGIRMAALMKLRVVHVFTHDSIGL
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHEEEEEECCCCCC
GEDGPTHQAVEHAASLRLIPNLDVWRPCDAAETAVAWAFALEQRTRPSALLLSRQNLPPQ
CCCCCHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHEEEECCCCCCH
ARTAEQVAQIRRGGYVLSDRPEPQVVLIGTGSEVSIAMEAQRLLDAVGIAARVVSLPCST
HHHHHHHHHHHHCCEEECCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCHHH
LFDRQEAAWHEQVLGRGIPRIGVEAGVTSWWGQYHCVAALGVNSFGESAPGPQVYEHFGL
HHHHHHHHHHHHHHHCCCCCCCHHHCCHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHCC
DAKALADLAREVLAREVRFVRSRS
CHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASTSADRVLRPESGRYDELANALRALAMDAVQQANSGHPGAPMGMAEMAVALWSGHLRH
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
NPGNPGWPDRDRFVLSNGHASMLLYALLHLSGYDLPIEELQRFRQLHSKTPGHPEVGLTP
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GVETTTGPLGQGLANAVGMALAGKLLGDEFNRPGHVVVDHHTYVFLGDGCLMEGISHEVC
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEECCCHHHHHHHHHHH
SLAGVWRLNKLIALYDDNGISIDGAVDAWFRDDTAARFRAYGWNVIGPIDGHDVVAIGRS
HHHHHHHHCCEEEEECCCCEEECCCHHHHHCCCHHHHHHHCCCCEECCCCCCCHHHHHHH
IADARRSADRPTLIVCRTTIGRGSPGRAGTAKAHGEPLGADEIAATRAAIGWHEAPFEIP
HHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
DTVRARWSARDLGARREAQWRLGFEAYRSEYPALAAEFERRIAGDLPSSFHEAASAAMIE
HHHHHHHCHHHHCCCCCHHHHCCHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LGQATTPVASRKASQQALAMLAPKIPEMLGGSADLTGSNLTDFPGCGAVRAGQPGGRHVN
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YGVREFGMAAIMNGLALHGGFIPYGGTFLTFSDYSRNGIRMAALMKLRVVHVFTHDSIGL
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHEEEEEECCCCCC
GEDGPTHQAVEHAASLRLIPNLDVWRPCDAAETAVAWAFALEQRTRPSALLLSRQNLPPQ
CCCCCHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHEEEECCCCCCH
ARTAEQVAQIRRGGYVLSDRPEPQVVLIGTGSEVSIAMEAQRLLDAVGIAARVVSLPCST
HHHHHHHHHHHHCCEEECCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCHHH
LFDRQEAAWHEQVLGRGIPRIGVEAGVTSWWGQYHCVAALGVNSFGESAPGPQVYEHFGL
HHHHHHHHHHHHHHHCCCCCCCHHHCCHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHCC
DAKALADLAREVLAREVRFVRSRS
CHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226680; 2559876 [H]