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The map label for this gene is cbbF1 [H]

Identifier: 94310449

GI number: 94310449

Start: 1628605

End: 1629444

Strand: Reverse

Name: cbbF1 [H]

Synonym: Rmet_1507

Alternate gene names: 94310449

Gene position: 1629444-1628605 (Counterclockwise)

Preceding gene: 335055531

Following gene: 94310448

Centisome position: 41.48

GC content: 66.31

Gene sequence:

>840_bases
TTGCACGGTAGTCCCTTGGCCCGGTCTCCCTCGCACTTGCATCGACTCTCCTCGGCAAGTGCCTTCACCCCCTCCGCTGT
AGCGGAGGGGGTTTTTCTGGAACTCCGGCCAAGCGGCCACCTTTGCCACACCGACGATCCCCGACGAGGAGAGGGTCATA
ACCCCCACCGGCATCACCCTGACCCAGTTCATCATCCAGTCCCAGCGCGCCCACCCGGCGGCCACCGGGGAGTTTCCGGA
CTGCTCAACGTGATCGCCACCGCCTGCAAGGTGATCGCCACCGCGGCCAGCCGCGGCGCCCTGGCGGGCGTGCTCGGCTC
GGCGGAGCACGAGAACGTTCAGGGCGAGGTGCAGAAGAAGCTCGACGTGATCAGCAACGCGATCCTCGTCCACGCCACCG
AGAGGGGTGGCCACCTAGTCGCCCTCGCCTCCGAGGAGATGGACACGATCTACCCGATCCCCGCGGCCTTCCCGCGAGGC
AAGTACCTGCTGGTCTTCGATCCCCTGGACGGCTCTTCCAACATCGACGCCAACATCTCGGTGGGCGCCATCTTCTCGGT
GCTGCGCTCGCCCGATCCGGAGGTGCCGCCGACCCTCGAACACTTCCTGCAGGCGGGCGCCGGGCAGGTCTGCGCCGGTT
ACGCCCTCTACGGGCCGGCGACCATGCTGGTGCTCACCACCGGTCAGGGCACCCACGGCTTCACCCTCGACCGGGATGTC
GGCGAGTTCATCCTCACCCATCCAATGCTGCGCATCCCCGCGGCGACCCAGGAGTTCGCCATCAACACCTCCAGGGGTCT
CCTCGTTTTCAGTGCAATAAGTGACGGTACGCAAAGCTAG

Upstream 100 bases:

>100_bases
CCCGGGCGCCGGGTTGATTAAGACAAACTAAACTGCCGATAAAGTATTTACAAATTGTTTTAAGCATTGCCTCCATCTAA
GCTGTCGTCCCGATAGTGCC

Downstream 100 bases:

>100_bases
CACTGGCGCGGGGGTGGTCTGGGTAGACCGTTGATTTCATTGACTTTCCTGTTCGCTTTGTAAACGGGTATGGTGGCCTC
CCACTTTTGAGGTTCACGAT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MHGSPLARSPSHLHRLSSASAFTPSAVAEGVFLELRPSGHLCHTDDPRRGEGHNPHRHHPDPVHHPVPARPPGGHRGVSG
LLNVIATACKVIATAASRGALAGVLGSAEHENVQGEVQKKLDVISNAILVHATERGGHLVALASEEMDTIYPIPAAFPRG
KYLLVFDPLDGSSNIDANISVGAIFSVLRSPDPEVPPTLEHFLQAGAGQVCAGYALYGPATMLVLTTGQGTHGFTLDRDV
GEFILTHPMLRIPAATQEFAINTSRGLLVFSAISDGTQS

Sequences:

>Translated_279_residues
MHGSPLARSPSHLHRLSSASAFTPSAVAEGVFLELRPSGHLCHTDDPRRGEGHNPHRHHPDPVHHPVPARPPGGHRGVSG
LLNVIATACKVIATAASRGALAGVLGSAEHENVQGEVQKKLDVISNAILVHATERGGHLVALASEEMDTIYPIPAAFPRG
KYLLVFDPLDGSSNIDANISVGAIFSVLRSPDPEVPPTLEHFLQAGAGQVCAGYALYGPATMLVLTTGQGTHGFTLDRDV
GEFILTHPMLRIPAATQEFAINTSRGLLVFSAISDGTQS
>Mature_279_residues
MHGSPLARSPSHLHRLSSASAFTPSAVAEGVFLELRPSGHLCHTDDPRRGEGHNPHRHHPDPVHHPVPARPPGGHRGVSG
LLNVIATACKVIATAASRGALAGVLGSAEHENVQGEVQKKLDVISNAILVHATERGGHLVALASEEMDTIYPIPAAFPRG
KYLLVFDPLDGSSNIDANISVGAIFSVLRSPDPEVPPTLEHFLQAGAGQVCAGYALYGPATMLVLTTGQGTHGFTLDRDV
GEFILTHPMLRIPAATQEFAINTSRGLLVFSAISDGTQS

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=194, Percent_Identity=41.7525773195876, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI189083692, Length=193, Percent_Identity=40.9326424870466, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI16579888, Length=193, Percent_Identity=40.9326424870466, Blast_Score=127, Evalue=9e-30,
Organism=Escherichia coli, GI1790679, Length=186, Percent_Identity=44.0860215053763, Blast_Score=150, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17508131, Length=185, Percent_Identity=43.7837837837838, Blast_Score=153, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6323409, Length=187, Percent_Identity=41.7112299465241, Blast_Score=139, Evalue=4e-34,
Organism=Drosophila melanogaster, GI45550998, Length=185, Percent_Identity=43.2432432432432, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI19921562, Length=185, Percent_Identity=43.2432432432432, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 29346; Mature: 29346

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGSPLARSPSHLHRLSSASAFTPSAVAEGVFLELRPSGHLCHTDDPRRGEGHNPHRHHP
CCCCCCCCCHHHHHHHHCCCCCCHHHHHCCEEEEECCCCCEECCCCCCCCCCCCCCCCCC
DPVHHPVPARPPGGHRGVSGLLNVIATACKVIATAASRGALAGVLGSAEHENVQGEVQKK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHH
LDVISNAILVHATERGGHLVALASEEMDTIYPIPAAFPRGKYLLVFDPLDGSSNIDANIS
HHHHHCEEEEEEECCCCEEEEEECCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCCCH
VGAIFSVLRSPDPEVPPTLEHFLQAGAGQVCAGYALYGPATMLVLTTGQGTHGFTLDRDV
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEECCEEEEEEECCCCCCCEEECCHH
GEFILTHPMLRIPAATQEFAINTSRGLLVFSAISDGTQS
HHHHHHCCHHCCCCCCHHHEEECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MHGSPLARSPSHLHRLSSASAFTPSAVAEGVFLELRPSGHLCHTDDPRRGEGHNPHRHHP
CCCCCCCCCHHHHHHHHCCCCCCHHHHHCCEEEEECCCCCEECCCCCCCCCCCCCCCCCC
DPVHHPVPARPPGGHRGVSGLLNVIATACKVIATAASRGALAGVLGSAEHENVQGEVQKK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHH
LDVISNAILVHATERGGHLVALASEEMDTIYPIPAAFPRGKYLLVFDPLDGSSNIDANIS
HHHHHCEEEEEEECCCCEEEEEECCCCCEEECCCCCCCCCCEEEEEECCCCCCCCCCCCH
VGAIFSVLRSPDPEVPPTLEHFLQAGAGQVCAGYALYGPATMLVLTTGQGTHGFTLDRDV
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEECCEEEEEEECCCCCCCEEECCHH
GEFILTHPMLRIPAATQEFAINTSRGLLVFSAISDGTQS
HHHHHHCCHHCCCCCCHHHEEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA