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The map label for this gene is cbbA1 [H]

Identifier: 94310434

GI number: 94310434

Start: 1614223

End: 1615083

Strand: Reverse

Name: cbbA1 [H]

Synonym: Rmet_1492

Alternate gene names: 94310434

Gene position: 1615083-1614223 (Counterclockwise)

Preceding gene: 94310438

Following gene: 94310432

Centisome position: 41.12

GC content: 68.41

Gene sequence:

>861_bases
ATGCCCCTGGTCAACATGAAGGACATGCTCGACCATGCCCATGCCCACGGTTACGCGGTGGGGGCCTTCGATCTGGTTGG
CCTGGATTTCCTGGAGGCCATCGTCGTCGGCGCGGAACGCGCCCGCGCACCGGTGATCCTGAGCCTGGCCGAATCGCATT
TCAGCCACTTCGATCTCGAGCTGGCCATGCCCGCCGTGGAAGCGGCGGCGCGGCGCGCCCAGGTGCCGGTGGCCATCCAT
CTCGACCACGGCGCGAGCCTCGATTCGGCCATCCGGGCCATTCGTCTCGGGGCCAACGGAGTGATGGTGGATGCCTCGCA
CCTGGATATCGGCGACAACATCGACGCGACCCGGGCCGTGACCGCGATGGCCCACGCCTGCGGCGTCTGCGTCGAGGGCG
AGCTGGGCTACGTGCCGGGTGTCGAGGGCGAAGATGCCGAGCGCCATCCCGGCCCGGTCCAATACACCACCGTGGCGGAA
GCCAAGGCCTTCGTGGAACGCACCGGCGTTGATTGCCTGGCCGTCTCCGTCGGCACCGTGCATGGCCGCATGAAGGACAA
ACCCGGGCTGGACTGGGGCCGGCTCAAGGACATCCACGCCGCGCTGGGGCTGCCCCTCGTCATCCATGGCGGCACCGGCC
TGTCCGATGACCAGTTCCGCAAGCTCATCACCTTCGGCGTGGCCAAGATCAATTACTACACCGCGCTGGCCGACGCCGCC
GGGGACGCCATCCGCGCCGCCGCTCGCGCCGGGGCGAGGAGCTACACGGCCCTGCTCGCCGGGGTGCGCGAGCCCATCGC
CGCCGAGGTAGAACGCTGCCTGCGGGTCTTGGGGTCTCCTCGTTTTCAGTGCAATAAGTGA

Upstream 100 bases:

>100_bases
CGGTTAAGAGCGCCCCCAGGAAACGGCTTGGCCGTTTCCGCCCCCCGAGGGGGACAAAAAAACTCGGGGCGGCCCTTCGT
TTTTTTGGGAGGAAAACGCC

Downstream 100 bases:

>100_bases
CGGTACGAAAAGCTAGCACTGGCGCGGAGGTGGTGTTGGTAGATCGTTGATTTCATTGACTTTCCTGTTCACTTTCAAAT
CTGCGATTCGTGGCGTCAAA

Product: Fructose-bisphosphate aldolase 1 (Fba)

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPLVNMKDMLDHAHAHGYAVGAFDLVGLDFLEAIVVGAERARAPVILSLAESHFSHFDLELAMPAVEAAARRAQVPVAIH
LDHGASLDSAIRAIRLGANGVMVDASHLDIGDNIDATRAVTAMAHACGVCVEGELGYVPGVEGEDAERHPGPVQYTTVAE
AKAFVERTGVDCLAVSVGTVHGRMKDKPGLDWGRLKDIHAALGLPLVIHGGTGLSDDQFRKLITFGVAKINYYTALADAA
GDAIRAAARAGARSYTALLAGVREPIAAEVERCLRVLGSPRFQCNK

Sequences:

>Translated_286_residues
MPLVNMKDMLDHAHAHGYAVGAFDLVGLDFLEAIVVGAERARAPVILSLAESHFSHFDLELAMPAVEAAARRAQVPVAIH
LDHGASLDSAIRAIRLGANGVMVDASHLDIGDNIDATRAVTAMAHACGVCVEGELGYVPGVEGEDAERHPGPVQYTTVAE
AKAFVERTGVDCLAVSVGTVHGRMKDKPGLDWGRLKDIHAALGLPLVIHGGTGLSDDQFRKLITFGVAKINYYTALADAA
GDAIRAAARAGARSYTALLAGVREPIAAEVERCLRVLGSPRFQCNK
>Mature_285_residues
PLVNMKDMLDHAHAHGYAVGAFDLVGLDFLEAIVVGAERARAPVILSLAESHFSHFDLELAMPAVEAAARRAQVPVAIHL
DHGASLDSAIRAIRLGANGVMVDASHLDIGDNIDATRAVTAMAHACGVCVEGELGYVPGVEGEDAERHPGPVQYTTVAEA
KAFVERTGVDCLAVSVGTVHGRMKDKPGLDWGRLKDIHAALGLPLVIHGGTGLSDDQFRKLITFGVAKINYYTALADAAG
DAIRAAARAGARSYTALLAGVREPIAAEVERCLRVLGSPRFQCNK

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=245, Percent_Identity=38.7755102040816, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1789526, Length=246, Percent_Identity=36.5853658536585, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1788072, Length=262, Percent_Identity=33.969465648855, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30154; Mature: 30023

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVNMKDMLDHAHAHGYAVGAFDLVGLDFLEAIVVGAERARAPVILSLAESHFSHFDLE
CCCCCHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCHH
LAMPAVEAAARRAQVPVAIHLDHGASLDSAIRAIRLGANGVMVDASHLDIGDNIDATRAV
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHH
TAMAHACGVCVEGELGYVPGVEGEDAERHPGPVQYTTVAEAKAFVERTGVDCLAVSVGTV
HHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEEHHH
HGRMKDKPGLDWGRLKDIHAALGLPLVIHGGTGLSDDQFRKLITFGVAKINYYTALADAA
HCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GDAIRAAARAGARSYTALLAGVREPIAAEVERCLRVLGSPRFQCNK
HHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PLVNMKDMLDHAHAHGYAVGAFDLVGLDFLEAIVVGAERARAPVILSLAESHFSHFDLE
CCCCHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCHH
LAMPAVEAAARRAQVPVAIHLDHGASLDSAIRAIRLGANGVMVDASHLDIGDNIDATRAV
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHH
TAMAHACGVCVEGELGYVPGVEGEDAERHPGPVQYTTVAEAKAFVERTGVDCLAVSVGTV
HHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEEHHH
HGRMKDKPGLDWGRLKDIHAALGLPLVIHGGTGLSDDQFRKLITFGVAKINYYTALADAA
HCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GDAIRAAARAGARSYTALLAGVREPIAAEVERCLRVLGSPRFQCNK
HHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2457578; 1640835; 9353933; 9384377; 1556067 [H]