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The map label for this gene is fabZ [H]

Identifier: 94310388

GI number: 94310388

Start: 1568289

End: 1568741

Strand: Direct

Name: fabZ [H]

Synonym: Rmet_1446

Alternate gene names: 94310388

Gene position: 1568289-1568741 (Clockwise)

Preceding gene: 94310387

Following gene: 94310389

Centisome position: 39.92

GC content: 60.04

Gene sequence:

>453_bases
ATGACCGCATCCGAAATCGATATCCGCAAGATCCTGAAGCTGCTGCCGCATCGGTATCCGATCCTGCTGGTCGACCGTGT
GCTCGAGTTCGAACCGCAGAAGCGGATCAAGACGCTGAAGAACGTGACGATCAACGAGCCGTACTTCATGGGCCACTTCC
CGGACCAACCGGTGATGCCGGGCGTCATGATCCTCGAGGCACTGGCTCAGTCCGCCGGTCTTCTGACGTTCGGCGCCGAT
ATGGAGCGCAAGGAAGGTGCGTTGTATTACTTCGTCGGGATCGACGGCGCGCGCTTCAAGCGCGTGGTGTATCCGGGCGA
TCAGCTTCACCTGAACGTGACCGTGGAGCGCTATATCCGCGGAATCTGGAAGTTCAAGGCCAGCGCGACCGTGGACGGTG
AGGTGGCCTGCGAGGCCGAACTGATGTGCACCGTGAAGCAAGCCGAAGGCTAA

Upstream 100 bases:

>100_bases
GCTTGTCAAAGCTGCGCGAACGTGTCGTGCAACTGGAACGCAGGCAGCGCGGTGAAAACAACGCCCCCGCACAGAACAAA
CAAGACGAAGAGAAATCATC

Downstream 100 bases:

>100_bases
GCACGGACCCAAAGCAGAACAGACCACAGGACAGCACGTATGACGCAAATCCATTCCACCGCACTAGTCGATCCGAAGGC
GGAACTGGCTGACGATGTTA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTASEIDIRKILKLLPHRYPILLVDRVLEFEPQKRIKTLKNVTINEPYFMGHFPDQPVMPGVMILEALAQSAGLLTFGAD
MERKEGALYYFVGIDGARFKRVVYPGDQLHLNVTVERYIRGIWKFKASATVDGEVACEAELMCTVKQAEG

Sequences:

>Translated_150_residues
MTASEIDIRKILKLLPHRYPILLVDRVLEFEPQKRIKTLKNVTINEPYFMGHFPDQPVMPGVMILEALAQSAGLLTFGAD
MERKEGALYYFVGIDGARFKRVVYPGDQLHLNVTVERYIRGIWKFKASATVDGEVACEAELMCTVKQAEG
>Mature_149_residues
TASEIDIRKILKLLPHRYPILLVDRVLEFEPQKRIKTLKNVTINEPYFMGHFPDQPVMPGVMILEALAQSAGLLTFGADM
ERKEGALYYFVGIDGARFKRVVYPGDQLHLNVTVERYIRGIWKFKASATVDGEVACEAELMCTVKQAEG

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=55.7971014492754, Blast_Score=171, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 16988; Mature: 16857

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASEIDIRKILKLLPHRYPILLVDRVLEFEPQKRIKTLKNVTINEPYFMGHFPDQPVMP
CCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCC
GVMILEALAQSAGLLTFGADMERKEGALYYFVGIDGARFKRVVYPGDQLHLNVTVERYIR
HHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHEEEEECCCCEEEEEEEHHHHHH
GIWKFKASATVDGEVACEAELMCTVKQAEG
HHHHHCCCCCCCCCEEECEEEEEEEECCCC
>Mature Secondary Structure 
TASEIDIRKILKLLPHRYPILLVDRVLEFEPQKRIKTLKNVTINEPYFMGHFPDQPVMP
CCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCC
GVMILEALAQSAGLLTFGADMERKEGALYYFVGIDGARFKRVVYPGDQLHLNVTVERYIR
HHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHEEEEECCCCEEEEEEEHHHHHH
GIWKFKASATVDGEVACEAELMCTVKQAEG
HHHHHCCCCCCCCCEEECEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA