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The map label for this gene is aceB [H]

Identifier: 94310332

GI number: 94310332

Start: 1499337

End: 1500920

Strand: Direct

Name: aceB [H]

Synonym: Rmet_1390

Alternate gene names: 94310332

Gene position: 1499337-1500920 (Clockwise)

Preceding gene: 94310331

Following gene: 94310334

Centisome position: 38.17

GC content: 63.51

Gene sequence:

>1584_bases
ATGGCTATCACGCTGCCCGCGGGCATGAAGATTACCGGCGAGATTCTGCCGGCTTATGAAGACATCCTGACGCCGGAAGC
CCTGGCCCTGGTCGACAAGCTGCACCGTGCCTTCGAGGCCCGCCGTCAGGAACTGCTGGCCGCGCGCGTGGCGCGCACCA
AGCGCCTCGACGCCGGCGAACTGCCCGACTTCCTGCCGGAAACCAAGAGCATCCGCGAAGGCGACTGGAAGGTTGCGCCG
GTGCCGAAGGCGCTGGAATGCCGCCGCGTGGAAATCACCGGTCCGGTCGAAGCCAAGATGGTGATCAACGCCTTCAACTC
GGGCGCTGACAGCTACATGACCGACTTCGAGGACTCCAACACCCCGAACTGGCACAACCAGATGCAGGGTCAGGTGAACC
TGAAGTCCGCCGTGCGCCGCACGCTGACGCTGGACAGCAACGGAAAGCACTACAAACTCAACGACAAGATCGCCACGCTG
CAGGTGCGTCCGCGCGGCTGGCACCTAGACGAGAAGCACGTCACGATCGACGGCAAGCGCGTCTCGGGCGGCATCTTCGA
CTTCGCGCTGTTCCTGTTCCACAACGCCAAGGAGCAGATTGCCCGCGGCGCCGGCCCGTTCTTCTATCTGCCGAAGATGG
AAAGCCATCTGGAAGCGCGTCTGTGGAACGACATCTTCGTGATGGCGCAGAAGGAAGTCGGTCTGCCGCAAGGCACGGTC
AAGGCCACGGTGCTGATCGAGACGATCCTGGCCGCGTTCGAGATGGAAGAAATCCTGTACGAACTGCGCGAGCACAGCGC
CGGCCTGAACGCTGGCCGTTGGGACTACATCTTCTCGTGCATCAAGAAGTTCAAGGTCGACAAGAACTTCTGCCTTGCCG
ACCGCGCCAAGGTGACGATGACCTCGCCGTTCATGCGCGCCTACGCGCTGCTGCTGCTGAAGACCTGCCACAAGCGCGGC
GCGCCTGCGATCGGCGGCATGAGCGCGCTGATCCCGATCAAGAACGATCCGGAGAAGAACGCTATCGCCATGCAGGGCAT
CATCGGCGACAAGCGCCGTGACGCCACCGACGGCTACGACGGCGGCTGGGTGGCCCACCCGGGTCTGGTCGAGCCGGCAA
TGAAGGAATTCGTGGACGTGCTGGGCGACCGCCCGAACCAGTTCGACAAGCAACGTCCGGACGTCGAAGTGAAGGGTGCC
GACCTGCTGAACTTCCAGCCGGAAGCGCCGATCACCGAAGCCGGCCTGCGCATGAACATCAACGTCGGCATCCACTACCT
GGGCGCCTGGCTGGCTGGCAATGGCTGCGTGCCGATCCACAACCTGATGGAAGACGCCGCCACCGCCGAGATCTCGCGCT
CCCAGGTGTGGCAGTGGATCCGCTCGCCGAAGGGCAAGCTGGAAGACGGCCGCAAGGTGACCGCCGAGATGGTGCGCGCG
CTGATTCCGGAAGAACTGGCCAAGGTCCGCGAAGTGGTGGGCGCAGGCGCCACGTACGACCGTGCCGCGCAGATCTTCGA
GCAGATGTCGACTTCGGAAGACTTTGCCGAATTCCTGACGCTGCCGCTGTACGAAGAAGTCTGA

Upstream 100 bases:

>100_bases
CTGCTTGCTTTCGCTTCGCCACTGGTTACCGCCACTGGCGTTGCGCTCTGACGAGCCAGGCCAACCCTTAACACACCATC
GCACCTACAGGAGATGACTG

Downstream 100 bases:

>100_bases
GTCCGGGCGTCAGCCTGAAAAAAATCCCACGGTGATGAGCCGTGGGATTTTTTTTGCCGCCGTGACTGGGTAAGAGCGTC
GCGGTGGGGGCGTGTCCATG

Product: malate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MAITLPAGMKITGEILPAYEDILTPEALALVDKLHRAFEARRQELLAARVARTKRLDAGELPDFLPETKSIREGDWKVAP
VPKALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSNTPNWHNQMQGQVNLKSAVRRTLTLDSNGKHYKLNDKIATL
QVRPRGWHLDEKHVTIDGKRVSGGIFDFALFLFHNAKEQIARGAGPFFYLPKMESHLEARLWNDIFVMAQKEVGLPQGTV
KATVLIETILAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKVDKNFCLADRAKVTMTSPFMRAYALLLLKTCHKRG
APAIGGMSALIPIKNDPEKNAIAMQGIIGDKRRDATDGYDGGWVAHPGLVEPAMKEFVDVLGDRPNQFDKQRPDVEVKGA
DLLNFQPEAPITEAGLRMNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGKLEDGRKVTAEMVRA
LIPEELAKVREVVGAGATYDRAAQIFEQMSTSEDFAEFLTLPLYEEV

Sequences:

>Translated_527_residues
MAITLPAGMKITGEILPAYEDILTPEALALVDKLHRAFEARRQELLAARVARTKRLDAGELPDFLPETKSIREGDWKVAP
VPKALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSNTPNWHNQMQGQVNLKSAVRRTLTLDSNGKHYKLNDKIATL
QVRPRGWHLDEKHVTIDGKRVSGGIFDFALFLFHNAKEQIARGAGPFFYLPKMESHLEARLWNDIFVMAQKEVGLPQGTV
KATVLIETILAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKVDKNFCLADRAKVTMTSPFMRAYALLLLKTCHKRG
APAIGGMSALIPIKNDPEKNAIAMQGIIGDKRRDATDGYDGGWVAHPGLVEPAMKEFVDVLGDRPNQFDKQRPDVEVKGA
DLLNFQPEAPITEAGLRMNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGKLEDGRKVTAEMVRA
LIPEELAKVREVVGAGATYDRAAQIFEQMSTSEDFAEFLTLPLYEEV
>Mature_526_residues
AITLPAGMKITGEILPAYEDILTPEALALVDKLHRAFEARRQELLAARVARTKRLDAGELPDFLPETKSIREGDWKVAPV
PKALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSNTPNWHNQMQGQVNLKSAVRRTLTLDSNGKHYKLNDKIATLQ
VRPRGWHLDEKHVTIDGKRVSGGIFDFALFLFHNAKEQIARGAGPFFYLPKMESHLEARLWNDIFVMAQKEVGLPQGTVK
ATVLIETILAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKVDKNFCLADRAKVTMTSPFMRAYALLLLKTCHKRGA
PAIGGMSALIPIKNDPEKNAIAMQGIIGDKRRDATDGYDGGWVAHPGLVEPAMKEFVDVLGDRPNQFDKQRPDVEVKGAD
LLNFQPEAPITEAGLRMNINVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGKLEDGRKVTAEMVRAL
IPEELAKVREVVGAGATYDRAAQIFEQMSTSEDFAEFLTLPLYEEV

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=508, Percent_Identity=48.8188976377953, Blast_Score=492, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17561814, Length=526, Percent_Identity=48.6692015209125, Blast_Score=497, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI71982926, Length=420, Percent_Identity=49.2857142857143, Blast_Score=406, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6324212, Length=515, Percent_Identity=48.7378640776699, Blast_Score=501, Evalue=1e-142,
Organism=Saccharomyces cerevisiae, GI6322222, Length=515, Percent_Identity=49.126213592233, Blast_Score=495, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 58842; Mature: 58711

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00510 MALATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITLPAGMKITGEILPAYEDILTPEALALVDKLHRAFEARRQELLAARVARTKRLDAGE
CEEECCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LPDFLPETKSIREGDWKVAPVPKALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSN
CCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCCCHHHHHEEHHCCCCHHHHHCCCCCC
TPNWHNQMQGQVNLKSAVRRTLTLDSNGKHYKLNDKIATLQVRPRGWHLDEKHVTIDGKR
CCCHHHHCCCCEEHHHHHHHHEEECCCCCEEEECCCEEEEEECCCCCCCCCCEEEECCCC
VSGGIFDFALFLFHNAKEQIARGAGPFFYLPKMESHLEARLWNDIFVMAQKEVGLPQGTV
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHEEEEHHCCCCCCHH
KATVLIETILAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKVDKNFCLADRAKVTM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEE
TSPFMRAYALLLLKTCHKRGAPAIGGMSALIPIKNDPEKNAIAMQGIIGDKRRDATDGYD
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCC
GGWVAHPGLVEPAMKEFVDVLGDRPNQFDKQRPDVEVKGADLLNFQPEAPITEAGLRMNI
CCEECCCCCCCHHHHHHHHHHCCCCCHHHCCCCCEEECCCCEECCCCCCCCCCCCEEEEE
NVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGKLEDGRKVTAEMVRA
EECCEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LIPEELAKVREVVGAGATYDRAAQIFEQMSTSEDFAEFLTLPLYEEV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHCC
>Mature Secondary Structure 
AITLPAGMKITGEILPAYEDILTPEALALVDKLHRAFEARRQELLAARVARTKRLDAGE
EEECCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LPDFLPETKSIREGDWKVAPVPKALECRRVEITGPVEAKMVINAFNSGADSYMTDFEDSN
CCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCCCHHHHHEEHHCCCCHHHHHCCCCCC
TPNWHNQMQGQVNLKSAVRRTLTLDSNGKHYKLNDKIATLQVRPRGWHLDEKHVTIDGKR
CCCHHHHCCCCEEHHHHHHHHEEECCCCCEEEECCCEEEEEECCCCCCCCCCEEEECCCC
VSGGIFDFALFLFHNAKEQIARGAGPFFYLPKMESHLEARLWNDIFVMAQKEVGLPQGTV
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHEEEEHHCCCCCCHH
KATVLIETILAAFEMEEILYELREHSAGLNAGRWDYIFSCIKKFKVDKNFCLADRAKVTM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEE
TSPFMRAYALLLLKTCHKRGAPAIGGMSALIPIKNDPEKNAIAMQGIIGDKRRDATDGYD
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCC
GGWVAHPGLVEPAMKEFVDVLGDRPNQFDKQRPDVEVKGADLLNFQPEAPITEAGLRMNI
CCEECCCCCCCHHHHHHHHHHCCCCCHHHCCCCCEEECCCCEECCCCCCCCCCCCEEEEE
NVGIHYLGAWLAGNGCVPIHNLMEDAATAEISRSQVWQWIRSPKGKLEDGRKVTAEMVRA
EECCEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LIPEELAKVREVVGAGATYDRAAQIFEQMSTSEDFAEFLTLPLYEEV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA