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The map label for this gene is comL [H]

Identifier: 94310294

GI number: 94310294

Start: 1460941

End: 1461777

Strand: Reverse

Name: comL [H]

Synonym: Rmet_1352

Alternate gene names: 94310294

Gene position: 1461777-1460941 (Counterclockwise)

Preceding gene: 94310297

Following gene: 94310280

Centisome position: 37.21

GC content: 61.53

Gene sequence:

>837_bases
TTGCCCATGCAATTGCAGAGCATGAGACGCGCTAATTGGCGCGCGAGATTTGGAGCGATTTTGCTTGCAGGCGGCTGCGT
CATGCTGTCCGCGTGCGGCCTGCTGGGCGACCAGCCGGACGAAACGGCTGGCTGGTCAGCGAACAAATTATATTCTGAAG
CCAAGGATGCTCTAGATGGCGGCGACTACACGCGCGCCGTCAAGCTCTACGAGAAGCTCGAGGGCCGCTATCCATTTGGC
CGTTACGCCCAGCAGGCGCAGATCGATACGGCCTACGCCAACTACAAGGATGGCGAGACCGCTGCCGCGCTGGCTGCCGT
CGACCGCTTCATCCAGTTGCACCCGAGCCACCCGAACATCGATTACGCCTACTACCTCAAGGGGCTGATCAACTTCAACG
ACAACCTGGGCTGGCTGGGCCGGTTCTCCGGCCAGGATCTGAGCGAACGTGATCCGAAGGCGGCGCGAGCAGCCTATGAC
GCGTTCCAGATCCTGATCACCCGCTACCCGGACAGCAAGTACACGCCCGACGCCACGCTGCGCATGCAGTACATCGTCAA
CTCGCTGGCCCAGCACGAAGTTCACGCGGCGCGTTACTACTATCGCCGCGGCGCCTACCTGGCTGCGGTCAACCGCGCGC
AGCAGGCGCTGAAGGACTACGACGGCGCGCCGGCCAACGAGGAAGCGCTGTATATCATGGTCCGCTCGTATGATGCGCTG
GGCATGAAGGATCTGCGCGACGATGCCGCCCGCGTGATGGAACGCAACTATCCGAACAGCGACTACATCAAATATGGGCA
GCGCCGCAAGGACAAGTCCTGGTGGGAAGTGTTCTGA

Upstream 100 bases:

>100_bases
ACGTCCGCTACGGCGGTGGATTCGGTGTGGCGCTCCGGCCCGGTTTCGGGCTTGGGGCTTCGGCTATAATGCTTGGCGCT
ATTTTTCATCCGGGAACAGG

Downstream 100 bases:

>100_bases
GGTTGCCGAACCTGTCCGCAATGGACATTTCGATGCAAGCAACAAAAAAGTGCCGGTGTCAAGTCTTTCGCGCAAATCAC
GCAGGGCTTGAAACCGTATA

Product: DNA uptake lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MPMQLQSMRRANWRARFGAILLAGGCVMLSACGLLGDQPDETAGWSANKLYSEAKDALDGGDYTRAVKLYEKLEGRYPFG
RYAQQAQIDTAYANYKDGETAAALAAVDRFIQLHPSHPNIDYAYYLKGLINFNDNLGWLGRFSGQDLSERDPKAARAAYD
AFQILITRYPDSKYTPDATLRMQYIVNSLAQHEVHAARYYYRRGAYLAAVNRAQQALKDYDGAPANEEALYIMVRSYDAL
GMKDLRDDAARVMERNYPNSDYIKYGQRRKDKSWWEVF

Sequences:

>Translated_278_residues
MPMQLQSMRRANWRARFGAILLAGGCVMLSACGLLGDQPDETAGWSANKLYSEAKDALDGGDYTRAVKLYEKLEGRYPFG
RYAQQAQIDTAYANYKDGETAAALAAVDRFIQLHPSHPNIDYAYYLKGLINFNDNLGWLGRFSGQDLSERDPKAARAAYD
AFQILITRYPDSKYTPDATLRMQYIVNSLAQHEVHAARYYYRRGAYLAAVNRAQQALKDYDGAPANEEALYIMVRSYDAL
GMKDLRDDAARVMERNYPNSDYIKYGQRRKDKSWWEVF
>Mature_277_residues
PMQLQSMRRANWRARFGAILLAGGCVMLSACGLLGDQPDETAGWSANKLYSEAKDALDGGDYTRAVKLYEKLEGRYPFGR
YAQQAQIDTAYANYKDGETAAALAAVDRFIQLHPSHPNIDYAYYLKGLINFNDNLGWLGRFSGQDLSERDPKAARAAYDA
FQILITRYPDSKYTPDATLRMQYIVNSLAQHEVHAARYYYRRGAYLAAVNRAQQALKDYDGAPANEEALYIMVRSYDALG
MKDLRDDAARVMERNYPNSDYIKYGQRRKDKSWWEVF

Specific function: Required for efficient transformation of Neisseria gonorrhoeae by species-related DNA [H]

COG id: COG4105

COG function: function code R; DNA uptake lipoprotein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0169 (ComL) family [H]

Homologues:

Organism=Escherichia coli, GI1788947, Length=240, Percent_Identity=39.5833333333333, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017689
- InterPro:   IPR011990 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 31693; Mature: 31562

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMQLQSMRRANWRARFGAILLAGGCVMLSACGLLGDQPDETAGWSANKLYSEAKDALDG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCC
GDYTRAVKLYEKLEGRYPFGRYAQQAQIDTAYANYKDGETAAALAAVDRFIQLHPSHPNI
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
DYAYYLKGLINFNDNLGWLGRFSGQDLSERDPKAARAAYDAFQILITRYPDSKYTPDATL
CHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCHHH
RMQYIVNSLAQHEVHAARYYYRRGAYLAAVNRAQQALKDYDGAPANEEALYIMVRSYDAL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCC
GMKDLRDDAARVMERNYPNSDYIKYGQRRKDKSWWEVF
CHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure 
PMQLQSMRRANWRARFGAILLAGGCVMLSACGLLGDQPDETAGWSANKLYSEAKDALDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCC
GDYTRAVKLYEKLEGRYPFGRYAQQAQIDTAYANYKDGETAAALAAVDRFIQLHPSHPNI
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
DYAYYLKGLINFNDNLGWLGRFSGQDLSERDPKAARAAYDAFQILITRYPDSKYTPDATL
CHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCHHH
RMQYIVNSLAQHEVHAARYYYRRGAYLAAVNRAQQALKDYDGAPANEEALYIMVRSYDAL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCC
GMKDLRDDAARVMERNYPNSDYIKYGQRRKDKSWWEVF
CHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8830266 [H]