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The map label for this gene is ybdR [H]

Identifier: 94310252

GI number: 94310252

Start: 1424194

End: 1425255

Strand: Reverse

Name: ybdR [H]

Synonym: Rmet_1308

Alternate gene names: 94310252

Gene position: 1425255-1424194 (Counterclockwise)

Preceding gene: 94310253

Following gene: 94310251

Centisome position: 36.28

GC content: 55.18

Gene sequence:

>1062_bases
ATGAAAGCCGCAGTCTATTACGGTCCGCAGGATATTCGCTGTACGGATATTCCAGACCCTGTCATTCGCTCCGACCACGA
AATGCTAGTCAAAGTAACGGCCACATCGATATGTGGCTCCGATTTGCACCTTTACCGGGGCGCGCTTGATGGAATCATGG
AAAAAGGCAAGTCCCAAACAGGTCATGAGTTGATCGGCGAAGTCGTGGAGGTCGGTAAGAGCGTCGGGCGCTTCAAGCAG
GGGGATCGCGTCAGTATGGGGTACTCAGTCTCATGCGGCCACTGCTACATGTGCGAGGTTGGGCAGACCGCACATTGTGA
GACTACCAAAAACGCAGTCTATGGATTCGGCATACCTTTCGGCAGCATCAATGGAACTCATGCGGAGGCCCTGATCGTCC
CTCACGCGGATGGTCACGCGATGAATGTGCCGAAGGGAATTCCCGATGAAGCGGCGGTTACGCTTTCCTGCAACCTGCCG
TCGGCAATCATCGCCAACCGCCTGGCCGATATCCAGGTCGGGGAGAATGTTGCACTGGTGGGCTGCGGGCCGACGGGTAT
GATGACTCTCGATATCGCGCTGCACAGAGGGCCAGGGCGCGTGGTTGTGCTCGATAAGGTTGCCCATCGTCTTGACGTCG
TGCGCAAAAAAGGGGGCGTGGCGATTGATGCGAACCAGGAAGACTGGAAAGAAAAAGCACTGGCAGAAACCGGCGGACGT
GGCTTTGACAAAGTGATCGAGGTGGTCGGTTATCCCGAAACCCTACAGATGTGCCTCGATCTGGTTCGCCCCGGCGGAAC
GGTTGCCGCGATCGGCGTTTTCTGCGACTCAACTTTCAATCTGAATTTGGCCGATGTGTTTCTGCGCAATATCAGCTTGC
ACATGAATGGCTTCGCTAACGCCCAGCCTTACATGTGGGAGGCATTGCGGCTGATGGAGCGTGGTGTGATCAATCCGCAA
GAGTACTTTTCACACGCGTTCGAACTTGCTGATGTCGACAAGGCATTCTCGGTCTTTCATCAGAAATCGGACAGCGCAAT
GAAGGTACTGATCCGGCCATAA

Upstream 100 bases:

>100_bases
GTTTTTGAACTGGCCTCTTAAGTATGAAGAGGGGTTGAGACATCAGGATACGGGAAGGTGAAAGCACCACTTATGCTAAC
TAATCTATAAGGAATCCAAA

Downstream 100 bases:

>100_bases
AGCTGCTTCGACGTAAAGCGAGGGTGAGCGCGAGAACGCTCATACCATTATTAGAAAAAATCTGGTAAGGAGACGAAATT
GAAGATCAATCAGAGTTGTG

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKAAVYYGPQDIRCTDIPDPVIRSDHEMLVKVTATSICGSDLHLYRGALDGIMEKGKSQTGHELIGEVVEVGKSVGRFKQ
GDRVSMGYSVSCGHCYMCEVGQTAHCETTKNAVYGFGIPFGSINGTHAEALIVPHADGHAMNVPKGIPDEAAVTLSCNLP
SAIIANRLADIQVGENVALVGCGPTGMMTLDIALHRGPGRVVVLDKVAHRLDVVRKKGGVAIDANQEDWKEKALAETGGR
GFDKVIEVVGYPETLQMCLDLVRPGGTVAAIGVFCDSTFNLNLADVFLRNISLHMNGFANAQPYMWEALRLMERGVINPQ
EYFSHAFELADVDKAFSVFHQKSDSAMKVLIRP

Sequences:

>Translated_353_residues
MKAAVYYGPQDIRCTDIPDPVIRSDHEMLVKVTATSICGSDLHLYRGALDGIMEKGKSQTGHELIGEVVEVGKSVGRFKQ
GDRVSMGYSVSCGHCYMCEVGQTAHCETTKNAVYGFGIPFGSINGTHAEALIVPHADGHAMNVPKGIPDEAAVTLSCNLP
SAIIANRLADIQVGENVALVGCGPTGMMTLDIALHRGPGRVVVLDKVAHRLDVVRKKGGVAIDANQEDWKEKALAETGGR
GFDKVIEVVGYPETLQMCLDLVRPGGTVAAIGVFCDSTFNLNLADVFLRNISLHMNGFANAQPYMWEALRLMERGVINPQ
EYFSHAFELADVDKAFSVFHQKSDSAMKVLIRP
>Mature_353_residues
MKAAVYYGPQDIRCTDIPDPVIRSDHEMLVKVTATSICGSDLHLYRGALDGIMEKGKSQTGHELIGEVVEVGKSVGRFKQ
GDRVSMGYSVSCGHCYMCEVGQTAHCETTKNAVYGFGIPFGSINGTHAEALIVPHADGHAMNVPKGIPDEAAVTLSCNLP
SAIIANRLADIQVGENVALVGCGPTGMMTLDIALHRGPGRVVVLDKVAHRLDVVRKKGGVAIDANQEDWKEKALAETGGR
GFDKVIEVVGYPETLQMCLDLVRPGGTVAAIGVFCDSTFNLNLADVFLRNISLHMNGFANAQPYMWEALRLMERGVINPQ
EYFSHAFELADVDKAFSVFHQKSDSAMKVLIRP

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=353, Percent_Identity=25.2124645892351, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786825, Length=391, Percent_Identity=30.690537084399, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1790045, Length=348, Percent_Identity=30.1724137931034, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787863, Length=363, Percent_Identity=28.6501377410468, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI226510992, Length=324, Percent_Identity=30.8641975308642, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788073, Length=339, Percent_Identity=28.9085545722714, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788075, Length=366, Percent_Identity=26.5027322404372, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082125, Length=339, Percent_Identity=25.6637168141593, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081918, Length=345, Percent_Identity=28.695652173913, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790718, Length=334, Percent_Identity=26.6467065868263, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786552, Length=379, Percent_Identity=26.1213720316623, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788407, Length=284, Percent_Identity=24.2957746478873, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=360, Percent_Identity=27.5, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17562878, Length=222, Percent_Identity=32.8828828828829, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71988145, Length=337, Percent_Identity=27.0029673590504, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562584, Length=345, Percent_Identity=25.2173913043478, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562582, Length=315, Percent_Identity=24.7619047619048, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=334, Percent_Identity=27.5449101796407, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6319955, Length=334, Percent_Identity=27.5449101796407, Blast_Score=102, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6319258, Length=392, Percent_Identity=25.5102040816327, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319257, Length=387, Percent_Identity=23.7726098191214, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320033, Length=345, Percent_Identity=23.768115942029, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=343, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=321, Percent_Identity=24.9221183800623, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=324, Percent_Identity=23.4567901234568, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323961, Length=324, Percent_Identity=22.8395061728395, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17737897, Length=354, Percent_Identity=27.683615819209, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI17137530, Length=354, Percent_Identity=27.683615819209, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI221457811, Length=333, Percent_Identity=27.3273273273273, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45551930, Length=333, Percent_Identity=27.3273273273273, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45550770, Length=333, Percent_Identity=27.3273273273273, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17737895, Length=342, Percent_Identity=23.6842105263158, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38129; Mature: 38129

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVYYGPQDIRCTDIPDPVIRSDHEMLVKVTATSICGSDLHLYRGALDGIMEKGKSQT
CCCEEEECCCCCEECCCCCHHHCCCCEEEEEEEEHHHCCCHHHHHHHHHHHHHHHCCCCC
GHELIGEVVEVGKSVGRFKQGDRVSMGYSVSCGHCYMCEVGQTAHCETTKNAVYGFGIPF
HHHHHHHHHHHHHHHHHCCCCCEEECCEEECCCCEEEECCCCCCCCCCCCCCEEECCCCC
GSINGTHAEALIVPHADGHAMNVPKGIPDEAAVTLSCNLPSAIIANRLADIQVGENVALV
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCEEECCCEEEE
GCGPTGMMTLDIALHRGPGRVVVLDKVAHRLDVVRKKGGVAIDANQEDWKEKALAETGGR
EECCCCEEEEEEEEECCCCCEEEHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCC
GFDKVIEVVGYPETLQMCLDLVRPGGTVAAIGVFCDSTFNLNLADVFLRNISLHMNGFAN
CHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHEEECCCCC
AQPYMWEALRLMERGVINPQEYFSHAFELADVDKAFSVFHQKSDSAMKVLIRP
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MKAAVYYGPQDIRCTDIPDPVIRSDHEMLVKVTATSICGSDLHLYRGALDGIMEKGKSQT
CCCEEEECCCCCEECCCCCHHHCCCCEEEEEEEEHHHCCCHHHHHHHHHHHHHHHCCCCC
GHELIGEVVEVGKSVGRFKQGDRVSMGYSVSCGHCYMCEVGQTAHCETTKNAVYGFGIPF
HHHHHHHHHHHHHHHHHCCCCCEEECCEEECCCCEEEECCCCCCCCCCCCCCEEECCCCC
GSINGTHAEALIVPHADGHAMNVPKGIPDEAAVTLSCNLPSAIIANRLADIQVGENVALV
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCEEECCCEEEE
GCGPTGMMTLDIALHRGPGRVVVLDKVAHRLDVVRKKGGVAIDANQEDWKEKALAETGGR
EECCCCEEEEEEEEECCCCCEEEHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCC
GFDKVIEVVGYPETLQMCLDLVRPGGTVAAIGVFCDSTFNLNLADVFLRNISLHMNGFAN
CHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHEEECCCCC
AQPYMWEALRLMERGVINPQEYFSHAFELADVDKAFSVFHQKSDSAMKVLIRP
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]