Click here to switch to the map view.

The map label for this gene is 94310146

Identifier: 94310146

GI number: 94310146

Start: 1320742

End: 1321713

Strand: Direct

Name: 94310146

Synonym: Rmet_1201

Alternate gene names: NA

Gene position: 1320742-1321713 (Clockwise)

Preceding gene: 94310144

Following gene: 94310147

Centisome position: 33.62

GC content: 63.58

Gene sequence:

>972_bases
ATGATGTCATTCAGGCACTTTCCGGGCCGCTCATCCTGCCCCATCCCGATGCTTGCCTTTTACGCCGATCATTTCGTCCT
GCCGTTGCCGCCGGGTCACCGTTTTCCGATGCGCAAATACAGCATGCTGCGTGATGCGGTGGTGCGCGAGGTAGGCGGGG
TGGAACTGCAAGAGGCGCCGCGTGCCGACGATGCAACACTCGCATTGGCCCACACCGCTGCCTATATCGAGGACGTTTCC
ACTGGCCAACTCGATGCCGCGCGTCAGCGCGAGATCGGCTTTCCCTGGTCGCATGAAATGGTGGAGCGTTCCCGGCGCTC
GGCCGGCGCGACGATTGCCGCTTGCAGGGTGGCGCTGGAGCAGGGTATCGCGGCGAATCTGGCTGGCGGCACTCACCACG
CGTACGCGGACAAAGGGGCGGGGTTTTGCGTATTCAATGACGCGGCGATTGCGGCGCGTCGCCTGCAGCGCGACGGCAGC
GTCCGGCGTGTGGCGGTCATCGATCTCGACGTCCACCAGGGCAACGGTACCGCATCGATCCTGCGTGATGACCCGACGAT
ATTTACGCTGTCGCTGCATGGCGAGAAGAACTACCCGTTTCGCAAGGAAGCTAGCGATCTCGACGTCGGGTTGCCGGATG
GGTGCGATGACGGTACCTATGCCGTCGCGCTGGCGTCCGCGCTAGAAACCCTGTTCGCACGATTCGATCCCGATCTGCTG
ATCTACCTGGCCGGCGCCGATCCTCATGAGGGTGATCGCCTGGGGCGATTGAAGCTCACGATGGCCGGTCTCGCGCAGCG
AGACAGCATGGTGTTCGAAGCGGCACGATCGCGTGGGTTGCCGGTCGCCGTTGCCATGGCGGGTGGCTATGGCAACCAGA
TCGAGGACACGGTCGCCGTGCATACGCAGACCATCATGCTTGCCGCGCGGTATCACGCACAGCTTGCCGCCGAACGCGCG
AGCGTGTCATGA

Upstream 100 bases:

>100_bases
TGATGCGGCGCGGGAGATCCTGGCGTTTTCTGGCGGTTTCGGCGATTGGTGTGCCGCAGCGGGAGGGGAGTGCTACCATC
GCTGACTGCCCGGTCGGATA

Downstream 100 bases:

>100_bases
ATCGATTGCAATCCGTTGGAACCTTGTGGCGGCCAGTGCGCTCATATCGAGCTGTCGTGCATCTGGCCGGTGCCGTTTGT
CCGAGCCATTCCTGACGCCA

Product: histone deacetylase superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MMSFRHFPGRSSCPIPMLAFYADHFVLPLPPGHRFPMRKYSMLRDAVVREVGGVELQEAPRADDATLALAHTAAYIEDVS
TGQLDAARQREIGFPWSHEMVERSRRSAGATIAACRVALEQGIAANLAGGTHHAYADKGAGFCVFNDAAIAARRLQRDGS
VRRVAVIDLDVHQGNGTASILRDDPTIFTLSLHGEKNYPFRKEASDLDVGLPDGCDDGTYAVALASALETLFARFDPDLL
IYLAGADPHEGDRLGRLKLTMAGLAQRDSMVFEAARSRGLPVAVAMAGGYGNQIEDTVAVHTQTIMLAARYHAQLAAERA
SVS

Sequences:

>Translated_323_residues
MMSFRHFPGRSSCPIPMLAFYADHFVLPLPPGHRFPMRKYSMLRDAVVREVGGVELQEAPRADDATLALAHTAAYIEDVS
TGQLDAARQREIGFPWSHEMVERSRRSAGATIAACRVALEQGIAANLAGGTHHAYADKGAGFCVFNDAAIAARRLQRDGS
VRRVAVIDLDVHQGNGTASILRDDPTIFTLSLHGEKNYPFRKEASDLDVGLPDGCDDGTYAVALASALETLFARFDPDLL
IYLAGADPHEGDRLGRLKLTMAGLAQRDSMVFEAARSRGLPVAVAMAGGYGNQIEDTVAVHTQTIMLAARYHAQLAAERA
SVS
>Mature_323_residues
MMSFRHFPGRSSCPIPMLAFYADHFVLPLPPGHRFPMRKYSMLRDAVVREVGGVELQEAPRADDATLALAHTAAYIEDVS
TGQLDAARQREIGFPWSHEMVERSRRSAGATIAACRVALEQGIAANLAGGTHHAYADKGAGFCVFNDAAIAARRLQRDGS
VRRVAVIDLDVHQGNGTASILRDDPTIFTLSLHGEKNYPFRKEASDLDVGLPDGCDDGTYAVALASALETLFARFDPDLL
IYLAGADPHEGDRLGRLKLTMAGLAQRDSMVFEAARSRGLPVAVAMAGGYGNQIEDTVAVHTQTIMLAARYHAQLAAERA
SVS

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=255, Percent_Identity=32.5490196078431, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI209862883, Length=248, Percent_Identity=32.6612903225806, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI13128860, Length=285, Percent_Identity=27.719298245614, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI8923769, Length=258, Percent_Identity=26.7441860465116, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI13128864, Length=220, Percent_Identity=29.5454545454545, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI20070354, Length=281, Percent_Identity=28.4697508896797, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI13128862, Length=211, Percent_Identity=29.3838862559242, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI293336691, Length=261, Percent_Identity=26.8199233716475, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI17158039, Length=210, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI30795202, Length=210, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI30795204, Length=210, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI62750349, Length=180, Percent_Identity=30, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI62750347, Length=180, Percent_Identity=30, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI169234807, Length=169, Percent_Identity=32.5443786982249, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI148539870, Length=169, Percent_Identity=32.5443786982249, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI153085395, Length=151, Percent_Identity=31.1258278145695, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI262073088, Length=183, Percent_Identity=25.6830601092896, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI262073092, Length=158, Percent_Identity=31.6455696202532, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI226529806, Length=168, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=270, Percent_Identity=29.2592592592593, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17537347, Length=277, Percent_Identity=28.8808664259928, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17508561, Length=204, Percent_Identity=32.843137254902, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193206283, Length=176, Percent_Identity=32.3863636363636, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17540332, Length=176, Percent_Identity=32.3863636363636, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17540334, Length=176, Percent_Identity=32.3863636363636, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17561978, Length=209, Percent_Identity=29.1866028708134, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25154022, Length=217, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI193209491, Length=179, Percent_Identity=31.2849162011173, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25154020, Length=216, Percent_Identity=28.7037037037037, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17534739, Length=257, Percent_Identity=26.4591439688716, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321244, Length=288, Percent_Identity=28.125, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6323999, Length=287, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324307, Length=209, Percent_Identity=28.7081339712919, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325325, Length=156, Percent_Identity=30.1282051282051, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24649807, Length=191, Percent_Identity=36.6492146596859, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24642144, Length=199, Percent_Identity=31.6582914572864, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24642142, Length=199, Percent_Identity=31.6582914572864, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360899, Length=199, Percent_Identity=31.6582914572864, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24642146, Length=199, Percent_Identity=31.6582914572864, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24657891, Length=204, Percent_Identity=29.9019607843137, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24644244, Length=180, Percent_Identity=28.8888888888889, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641720, Length=220, Percent_Identity=29.5454545454545, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281360801, Length=220, Percent_Identity=29.5454545454545, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281360799, Length=220, Percent_Identity=29.5454545454545, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34874; Mature: 34874

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSFRHFPGRSSCPIPMLAFYADHFVLPLPPGHRFPMRKYSMLRDAVVREVGGVELQEAP
CCCCCCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
RADDATLALAHTAAYIEDVSTGQLDAARQREIGFPWSHEMVERSRRSAGATIAACRVALE
CCCCCEEEHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
QGIAANLAGGTHHAYADKGAGFCVFNDAAIAARRLQRDGSVRRVAVIDLDVHQGNGTASI
CCCEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEE
LRDDPTIFTLSLHGEKNYPFRKEASDLDVGLPDGCDDGTYAVALASALETLFARFDPDLL
EECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
IYLAGADPHEGDRLGRLKLTMAGLAQRDSMVFEAARSRGLPVAVAMAGGYGNQIEDTVAV
EEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHH
HTQTIMLAARYHAQLAAERASVS
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSFRHFPGRSSCPIPMLAFYADHFVLPLPPGHRFPMRKYSMLRDAVVREVGGVELQEAP
CCCCCCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEECCCC
RADDATLALAHTAAYIEDVSTGQLDAARQREIGFPWSHEMVERSRRSAGATIAACRVALE
CCCCCEEEHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHH
QGIAANLAGGTHHAYADKGAGFCVFNDAAIAARRLQRDGSVRRVAVIDLDVHQGNGTASI
CCCEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEE
LRDDPTIFTLSLHGEKNYPFRKEASDLDVGLPDGCDDGTYAVALASALETLFARFDPDLL
EECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEE
IYLAGADPHEGDRLGRLKLTMAGLAQRDSMVFEAARSRGLPVAVAMAGGYGNQIEDTVAV
EEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHH
HTQTIMLAARYHAQLAAERASVS
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]