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The map label for this gene is ychM [C]

Identifier: 94310133

GI number: 94310133

Start: 1301500

End: 1303311

Strand: Reverse

Name: ychM [C]

Synonym: Rmet_1188

Alternate gene names: 94310133

Gene position: 1303311-1301500 (Counterclockwise)

Preceding gene: 94310134

Following gene: 94310129

Centisome position: 33.18

GC content: 65.95

Gene sequence:

>1812_bases
ATGCGTGCGAATCTGGCCCTGACGCGCTGGTTTCCCTGGCTCCCGCGCGTCACGCCGCTGACGCTGCGCGCCGATCTGGT
TGCCGGACTGCTTGGCGCGGTGCTGGTGCTACCGCAGGGCGTGGCCTTTGCCACGCTGGCCGGTCTACCCCCCCAGTACG
GCATCTATACGGCCGTGATCCCCTGCATCGTCGCCGCCCTGTTCGGCTCGAGCTGGCATGTGATGTCGGGACCGACCAAC
GCCAATTCCCTCGCGCTGTTCGCCATGCTGAGTCCGGTGGCATTTGCGGGCAGCCCCGCCTATATCTCGCTGGCGCTGGC
GGTCACGATGCTGGTCGGCATCCTGCAACTGGCGGTAGGCGCGCTCCGGCTCGGATCGCTCGCCAATTTCATTTCGCCAT
CGGTTCTACTCGGTTTCACCTGTGGCGCCGCGACCTTGATCGGACTTCACGCGCTGAAGGATCTGCTTGGGCTTGCCGTG
CCAACCGGCACGAGCGCATTCGGCGTGGTGCGCTTCCTGCTCGACAATCTCGACACGGTCAGCGGTAGCGCGTTGATCGT
CGGCGCCGTGACGCTGGCGGTCACGCTGCTCGTCAAACGGATCTCGCGCCGCGCGCCCTTCATGCTGATCGGCCTGCTCG
CCGGCTACGGCGTTGCGCTGCTGCTCAACTCCACTGGTTGGGGCGCCGCCAGGCATGTGAACGTGGTGGGGCCGATTCCA
TCGGCGATTCCACCATTCCATATCCCCGACATCAACTGGCGCACGGTGCCTGACCTGCTGGGCATTGCCTCGGCACTGAC
CATCGTCGCGCTCGGCCAGTCGATTTCGATTGCCAAGGCCGTGGCATTGCGCTCGGGCCAGCACATCGACGCCAACCGCG
AGTTCATCGGCCAGGGGCTGTCGAATATCGCGGGCGGATTTTTCTCCGGCTACATTTCTTGTGGATCGCTGAACCGCTCG
GTCCCGAATTTCGAGGCCGGCGCGCAGACGCCTCTGGCCAGCGTGTTCTCTGCGCTGCTGCTGGTCGTGCTCGTCATGGT
CAGCGCGCCGCTGCTGGCGCAGATTCCGCTGGCGGCGATCTCGGCCATGCTGCTGCTCGTGGCCTGGGGCCTGTTCGATT
TCCAGCGCCTGCGCCGTATCGCGCGACTCTCGCGCACCGAGTTCGCGATTGCGGTAGGCACGTTCGTCGCCACGCTGGCG
ATCCGGCTCGAGATGGCCGTATTGCTCGGCACGATTCTGTCGCTCGTCGCGTACCTGTATCGCACCTCGCGCCCCGCCGT
GCGCAGCCTCGTGCCGGATGCCGATGACCCTGGCCGCCGCTTCACACCGCTGGACGAACTGCGCCGACCCCAACCGGAAT
GTCCGCAGTTGAAGCTCCTGCGCATGGAAGGCGCGATCTACTTCGGCGCCGTGCAATACGTCACCGATCGCCTGCACTGG
CTGCGCACGGTCAACGCCAGCCAGAAGCATCTGCTGGCGATGACCAAGAGCATGAACTTCATCGACCTGGCCGGCGCGGA
GATGTGGGAAGCCGAGCTGGCCGAGCGGCGTGCAGCCGGCGGCAACCTCTATTTCCACCGTCCGCGCACGCAGGTCCTCG
AGACCTGGGAACAGACCGGTTTCACCGCCAAGCTCGGCGACGACCACATCTTCCCCACCAAGCGACAGGCGCTGCACACG
ATCATCGGCAGTCTTTCGCCCGACATCTGCGCGCAATGCCAGGCGCGCATCTTCGAGGAATGCGCGCAGCGCCCGGGAGC
CGTGCCGCGCTCGCCACAAGCCAACGCGTCAGACGCAGCGGCCTCTGCCTGA

Upstream 100 bases:

>100_bases
GCGGCAGTGCGCGACGTGTGTCATCGACAAGGAGCCGCGCCGCTGGGAGCAGCCGTCTGACCACACCCCTGTCGTGGCCA
CGCTCACGCTCGGCTAGCCG

Downstream 100 bases:

>100_bases
GCGGCAATCGGAACAACCAGACGTTGATGTAAGACGAAAGACGGTAGGTATGTGAGCGCGCCGGCCGGTCTACGCGTGAG
ACGTAGCCGAAGCCGGCGGC

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MRANLALTRWFPWLPRVTPLTLRADLVAGLLGAVLVLPQGVAFATLAGLPPQYGIYTAVIPCIVAALFGSSWHVMSGPTN
ANSLALFAMLSPVAFAGSPAYISLALAVTMLVGILQLAVGALRLGSLANFISPSVLLGFTCGAATLIGLHALKDLLGLAV
PTGTSAFGVVRFLLDNLDTVSGSALIVGAVTLAVTLLVKRISRRAPFMLIGLLAGYGVALLLNSTGWGAARHVNVVGPIP
SAIPPFHIPDINWRTVPDLLGIASALTIVALGQSISIAKAVALRSGQHIDANREFIGQGLSNIAGGFFSGYISCGSLNRS
VPNFEAGAQTPLASVFSALLLVVLVMVSAPLLAQIPLAAISAMLLLVAWGLFDFQRLRRIARLSRTEFAIAVGTFVATLA
IRLEMAVLLGTILSLVAYLYRTSRPAVRSLVPDADDPGRRFTPLDELRRPQPECPQLKLLRMEGAIYFGAVQYVTDRLHW
LRTVNASQKHLLAMTKSMNFIDLAGAEMWEAELAERRAAGGNLYFHRPRTQVLETWEQTGFTAKLGDDHIFPTKRQALHT
IIGSLSPDICAQCQARIFEECAQRPGAVPRSPQANASDAAASA

Sequences:

>Translated_603_residues
MRANLALTRWFPWLPRVTPLTLRADLVAGLLGAVLVLPQGVAFATLAGLPPQYGIYTAVIPCIVAALFGSSWHVMSGPTN
ANSLALFAMLSPVAFAGSPAYISLALAVTMLVGILQLAVGALRLGSLANFISPSVLLGFTCGAATLIGLHALKDLLGLAV
PTGTSAFGVVRFLLDNLDTVSGSALIVGAVTLAVTLLVKRISRRAPFMLIGLLAGYGVALLLNSTGWGAARHVNVVGPIP
SAIPPFHIPDINWRTVPDLLGIASALTIVALGQSISIAKAVALRSGQHIDANREFIGQGLSNIAGGFFSGYISCGSLNRS
VPNFEAGAQTPLASVFSALLLVVLVMVSAPLLAQIPLAAISAMLLLVAWGLFDFQRLRRIARLSRTEFAIAVGTFVATLA
IRLEMAVLLGTILSLVAYLYRTSRPAVRSLVPDADDPGRRFTPLDELRRPQPECPQLKLLRMEGAIYFGAVQYVTDRLHW
LRTVNASQKHLLAMTKSMNFIDLAGAEMWEAELAERRAAGGNLYFHRPRTQVLETWEQTGFTAKLGDDHIFPTKRQALHT
IIGSLSPDICAQCQARIFEECAQRPGAVPRSPQANASDAAASA
>Mature_603_residues
MRANLALTRWFPWLPRVTPLTLRADLVAGLLGAVLVLPQGVAFATLAGLPPQYGIYTAVIPCIVAALFGSSWHVMSGPTN
ANSLALFAMLSPVAFAGSPAYISLALAVTMLVGILQLAVGALRLGSLANFISPSVLLGFTCGAATLIGLHALKDLLGLAV
PTGTSAFGVVRFLLDNLDTVSGSALIVGAVTLAVTLLVKRISRRAPFMLIGLLAGYGVALLLNSTGWGAARHVNVVGPIP
SAIPPFHIPDINWRTVPDLLGIASALTIVALGQSISIAKAVALRSGQHIDANREFIGQGLSNIAGGFFSGYISCGSLNRS
VPNFEAGAQTPLASVFSALLLVVLVMVSAPLLAQIPLAAISAMLLLVAWGLFDFQRLRRIARLSRTEFAIAVGTFVATLA
IRLEMAVLLGTILSLVAYLYRTSRPAVRSLVPDADDPGRRFTPLDELRRPQPECPQLKLLRMEGAIYFGAVQYVTDRLHW
LRTVNASQKHLLAMTKSMNFIDLAGAEMWEAELAERRAAGGNLYFHRPRTQVLETWEQTGFTAKLGDDHIFPTKRQALHT
IIGSLSPDICAQCQARIFEECAQRPGAVPRSPQANASDAAASA

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI39752683, Length=545, Percent_Identity=28.4403669724771, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI45827800, Length=545, Percent_Identity=28.4403669724771, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI45827802, Length=448, Percent_Identity=30.3571428571429, Blast_Score=166, Evalue=8e-41,
Organism=Homo sapiens, GI94721257, Length=469, Percent_Identity=26.865671641791, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI94721253, Length=469, Percent_Identity=27.5053304904051, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI94721259, Length=469, Percent_Identity=26.865671641791, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI94721255, Length=469, Percent_Identity=27.5053304904051, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI269784651, Length=544, Percent_Identity=26.6544117647059, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI4557535, Length=513, Percent_Identity=26.9005847953216, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI20336282, Length=515, Percent_Identity=25.0485436893204, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI16306483, Length=515, Percent_Identity=25.0485436893204, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI4505697, Length=498, Percent_Identity=24.4979919678715, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI100913030, Length=515, Percent_Identity=23.6893203883495, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI47131207, Length=526, Percent_Identity=27.7566539923954, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI20336272, Length=526, Percent_Identity=27.7566539923954, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI217272867, Length=389, Percent_Identity=24.9357326478149, Blast_Score=113, Evalue=7e-25,
Organism=Homo sapiens, GI16418413, Length=389, Percent_Identity=24.9357326478149, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI65506789, Length=375, Percent_Identity=28.5333333333333, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI45827804, Length=263, Percent_Identity=29.6577946768061, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI262206105, Length=194, Percent_Identity=27.8350515463918, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI262206075, Length=194, Percent_Identity=27.8350515463918, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI262206069, Length=194, Percent_Identity=27.8350515463918, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI262206063, Length=194, Percent_Identity=27.8350515463918, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI87081859, Length=436, Percent_Identity=30.045871559633, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI86565215, Length=475, Percent_Identity=26.9473684210526, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17562578, Length=627, Percent_Identity=25.1993620414673, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17566848, Length=561, Percent_Identity=25.668449197861, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI86564196, Length=464, Percent_Identity=25.8620689655172, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI193203292, Length=518, Percent_Identity=24.5173745173745, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17551690, Length=501, Percent_Identity=22.3552894211577, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI86564876, Length=392, Percent_Identity=24.234693877551, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI86565213, Length=274, Percent_Identity=27.007299270073, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71982567, Length=406, Percent_Identity=25.3694581280788, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323121, Length=458, Percent_Identity=25.5458515283843, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319771, Length=390, Percent_Identity=25.1282051282051, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6325260, Length=521, Percent_Identity=21.8809980806142, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24663084, Length=566, Percent_Identity=28.0918727915194, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21357695, Length=566, Percent_Identity=28.0918727915194, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24647160, Length=465, Percent_Identity=29.4623655913978, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24649801, Length=460, Percent_Identity=25.6521739130435, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21355087, Length=479, Percent_Identity=28.8100208768267, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI21358229, Length=470, Percent_Identity=26.5957446808511, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24666186, Length=523, Percent_Identity=26.0038240917782, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24651449, Length=462, Percent_Identity=27.2727272727273, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI19922482, Length=523, Percent_Identity=24.282982791587, Blast_Score=138, Evalue=9e-33,
Organism=Drosophila melanogaster, GI85815873, Length=452, Percent_Identity=28.3185840707965, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI21358633, Length=494, Percent_Identity=26.1133603238866, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 64126; Mature: 64126

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRANLALTRWFPWLPRVTPLTLRADLVAGLLGAVLVLPQGVAFATLAGLPPQYGIYTAVI
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHH
PCIVAALFGSSWHVMSGPTNANSLALFAMLSPVAFAGSPAYISLALAVTMLVGILQLAVG
HHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ALRLGSLANFISPSVLLGFTCGAATLIGLHALKDLLGLAVPTGTSAFGVVRFLLDNLDTV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
SGSALIVGAVTLAVTLLVKRISRRAPFMLIGLLAGYGVALLLNSTGWGAARHVNVVGPIP
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCCEEEEEECCCC
SAIPPFHIPDINWRTVPDLLGIASALTIVALGQSISIAKAVALRSGQHIDANREFIGQGL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHCCH
SNIAGGFFSGYISCGSLNRSVPNFEAGAQTPLASVFSALLLVVLVMVSAPLLAQIPLAAI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SAMLLLVAWGLFDFQRLRRIARLSRTEFAIAVGTFVATLAIRLEMAVLLGTILSLVAYLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTSRPAVRSLVPDADDPGRRFTPLDELRRPQPECPQLKLLRMEGAIYFGAVQYVTDRLHW
HCCCHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
LRTVNASQKHLLAMTKSMNFIDLAGAEMWEAELAERRAAGGNLYFHRPRTQVLETWEQTG
HHHCCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCC
FTAKLGDDHIFPTKRQALHTIIGSLSPDICAQCQARIFEECAQRPGAVPRSPQANASDAA
CEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ASA
CCC
>Mature Secondary Structure
MRANLALTRWFPWLPRVTPLTLRADLVAGLLGAVLVLPQGVAFATLAGLPPQYGIYTAVI
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHH
PCIVAALFGSSWHVMSGPTNANSLALFAMLSPVAFAGSPAYISLALAVTMLVGILQLAVG
HHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ALRLGSLANFISPSVLLGFTCGAATLIGLHALKDLLGLAVPTGTSAFGVVRFLLDNLDTV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
SGSALIVGAVTLAVTLLVKRISRRAPFMLIGLLAGYGVALLLNSTGWGAARHVNVVGPIP
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCCEEEEEECCCC
SAIPPFHIPDINWRTVPDLLGIASALTIVALGQSISIAKAVALRSGQHIDANREFIGQGL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHCCH
SNIAGGFFSGYISCGSLNRSVPNFEAGAQTPLASVFSALLLVVLVMVSAPLLAQIPLAAI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SAMLLLVAWGLFDFQRLRRIARLSRTEFAIAVGTFVATLAIRLEMAVLLGTILSLVAYLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTSRPAVRSLVPDADDPGRRFTPLDELRRPQPECPQLKLLRMEGAIYFGAVQYVTDRLHW
HCCCHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
LRTVNASQKHLLAMTKSMNFIDLAGAEMWEAELAERRAAGGNLYFHRPRTQVLETWEQTG
HHHCCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCC
FTAKLGDDHIFPTKRQALHTIIGSLSPDICAQCQARIFEECAQRPGAVPRSPQANASDAA
CEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ASA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]