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The map label for this gene is glcD2 [H]

Identifier: 94310073

GI number: 94310073

Start: 1235111

End: 1236535

Strand: Reverse

Name: glcD2 [H]

Synonym: Rmet_1128

Alternate gene names: 94310073

Gene position: 1236535-1235111 (Counterclockwise)

Preceding gene: 94310074

Following gene: 94310066

Centisome position: 31.48

GC content: 65.47

Gene sequence:

>1425_bases
ATGCACTCCGATTCCTTCCTCGATCTTTGCCGCGCAGCCATCGGTTCGCAGAACGTGCTGACCGACCCGGCCGACAAGGC
ACCCTACCTGACCGACTGGCGCCGCCGCTACACCGGCGACGCGCTGGCCGTGCTGCGTCCCGGCTCGACCGAGGAAGTCG
CGGCGGTGATGCGTGCCTGCCATGCGCACAAGCTGGCCGTGGTGCCCCAGGGTGGCAACACAGGCCTGTGCGGCGGCGCC
ACCCCCGAACCCGGCGATGCTGCCGCGCGTGGCACGGTGGTGCTGTCCCTGCAGCGCATGAACCGCGTGCGGCAGGTCGA
CCCGCTCAATAACACGATCACCGTCGAGGCCGGCGTGATCCTGCAGCAACTGCAGGAGGCCGCGCAGACACACGGCCGGC
TGTTCCCGCTCTCGCTGGCGGCCGAAGGCAGCTGCACGATCGGCGGCAACCTGTCGACGAACGCCGGCGGCACCGCCGTG
CTGCGCTACGGCAACACGCGCGAACTCTGCCTGGGGCTCGAGGTCGTGAACATCAAGGGCGAGGTCTGGGATGGCCTGCG
CGGCCTGCGCAAGGACAATACCGGCTATGACCTGCGCGACCTGTTCATCGGCGCCGAAGGCACGCTCGGCATCATCACCG
CCGCGGTCATGAAGCTGTTTCCGGCGCCGCGCGCGCGGGTCACCGCGCTGGCCGCCGTTGAAAGCCCACGCGCCGCGCTG
GCGCTGCTGGCCATCGCGCAATCGCACGCGGGCGCCATGCTGACCGGTTTCGAGTTGATGTCCGCGATGTGCATGGATCT
GGTGACGAAGCACTACCCGCAGTTGCGCTACCCGTTCACCGCCCATCATCCGCAACTCGTTCTGCTGGAACTGTCCGACA
GCGAGAGCGAAGAACACGCGCGGACGATCTTCGAAAAAATGATGGAGGTAGCGTTCGAAGCCGGCGTGGTCAAGGATGCC
GTGGTGGCCGAATCGGTACAGCAGTCACGCGATTTCTGGAACCTGCGCGAACACATTCCGCTGGCGCAGGTCGAGGAAGG
CAAGAACATCAAGCACGATATCGCCGTGCCGATCTCGCGCGTGGCGGACTTCATCGAGACCACCGACACGCTGCTGCAAG
ACGCCTTCCCCGGCGCGCGCATGGTCACGTTCGGCCATCTTGGCGATGGCAACTTGCACTACAACGTGTCGCCGCCGGTC
GGCGTGGATCATGATCAGTTCCTGTCGCACCAGGATGCGATCAACCTGATCGTCCACAACAGCGTGCATGTCCACAACGG
CTCGATCTCGGCCGAACACGGCCTTGGCCAACTCAAGCGCGAGGAGAACCGCCGCTACAAGAGCGAGGTGGAACTGGCGA
TGATGCGGGCCATCAAGCAGGCGCTGGATCCGCAAGGGTTGATGAACCCCGGAAAGGTGGTTTGA

Upstream 100 bases:

>100_bases
GCACGATCCTCTATCTGCGACCCTTCAAGCGGCGCGCCAAGGCATTGACCAAAACAGCGACCAAGACGGCAACCAAAACG
CAATCCAACCACTGACTGCC

Downstream 100 bases:

>100_bases
GGATTCGGGCGGGGCATGGCAACCACATGCCCCGTCAGTGCGGCATCCCCCCGTCATCCCCCTCGAACAACGCCCCGCAC
AACGCCTCGCCCTCCTCCGT

Product: glycolate oxidase subunit glcD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MHSDSFLDLCRAAIGSQNVLTDPADKAPYLTDWRRRYTGDALAVLRPGSTEEVAAVMRACHAHKLAVVPQGGNTGLCGGA
TPEPGDAAARGTVVLSLQRMNRVRQVDPLNNTITVEAGVILQQLQEAAQTHGRLFPLSLAAEGSCTIGGNLSTNAGGTAV
LRYGNTRELCLGLEVVNIKGEVWDGLRGLRKDNTGYDLRDLFIGAEGTLGIITAAVMKLFPAPRARVTALAAVESPRAAL
ALLAIAQSHAGAMLTGFELMSAMCMDLVTKHYPQLRYPFTAHHPQLVLLELSDSESEEHARTIFEKMMEVAFEAGVVKDA
VVAESVQQSRDFWNLREHIPLAQVEEGKNIKHDIAVPISRVADFIETTDTLLQDAFPGARMVTFGHLGDGNLHYNVSPPV
GVDHDQFLSHQDAINLIVHNSVHVHNGSISAEHGLGQLKREENRRYKSEVELAMMRAIKQALDPQGLMNPGKVV

Sequences:

>Translated_474_residues
MHSDSFLDLCRAAIGSQNVLTDPADKAPYLTDWRRRYTGDALAVLRPGSTEEVAAVMRACHAHKLAVVPQGGNTGLCGGA
TPEPGDAAARGTVVLSLQRMNRVRQVDPLNNTITVEAGVILQQLQEAAQTHGRLFPLSLAAEGSCTIGGNLSTNAGGTAV
LRYGNTRELCLGLEVVNIKGEVWDGLRGLRKDNTGYDLRDLFIGAEGTLGIITAAVMKLFPAPRARVTALAAVESPRAAL
ALLAIAQSHAGAMLTGFELMSAMCMDLVTKHYPQLRYPFTAHHPQLVLLELSDSESEEHARTIFEKMMEVAFEAGVVKDA
VVAESVQQSRDFWNLREHIPLAQVEEGKNIKHDIAVPISRVADFIETTDTLLQDAFPGARMVTFGHLGDGNLHYNVSPPV
GVDHDQFLSHQDAINLIVHNSVHVHNGSISAEHGLGQLKREENRRYKSEVELAMMRAIKQALDPQGLMNPGKVV
>Mature_474_residues
MHSDSFLDLCRAAIGSQNVLTDPADKAPYLTDWRRRYTGDALAVLRPGSTEEVAAVMRACHAHKLAVVPQGGNTGLCGGA
TPEPGDAAARGTVVLSLQRMNRVRQVDPLNNTITVEAGVILQQLQEAAQTHGRLFPLSLAAEGSCTIGGNLSTNAGGTAV
LRYGNTRELCLGLEVVNIKGEVWDGLRGLRKDNTGYDLRDLFIGAEGTLGIITAAVMKLFPAPRARVTALAAVESPRAAL
ALLAIAQSHAGAMLTGFELMSAMCMDLVTKHYPQLRYPFTAHHPQLVLLELSDSESEEHARTIFEKMMEVAFEAGVVKDA
VVAESVQQSRDFWNLREHIPLAQVEEGKNIKHDIAVPISRVADFIETTDTLLQDAFPGARMVTFGHLGDGNLHYNVSPPV
GVDHDQFLSHQDAINLIVHNSVHVHNGSISAEHGLGQLKREENRRYKSEVELAMMRAIKQALDPQGLMNPGKVV

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=459, Percent_Identity=38.9978213507625, Blast_Score=285, Evalue=5e-77,
Organism=Homo sapiens, GI37595756, Length=479, Percent_Identity=30.4801670146138, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI37595754, Length=502, Percent_Identity=29.2828685258964, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI4501993, Length=200, Percent_Identity=30.5, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1789351, Length=466, Percent_Identity=29.1845493562232, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787977, Length=502, Percent_Identity=24.9003984063745, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI48994907, Length=503, Percent_Identity=22.6640159045726, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788454, Length=173, Percent_Identity=34.1040462427746, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534361, Length=456, Percent_Identity=34.8684210526316, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI71992373, Length=483, Percent_Identity=26.9151138716356, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71992381, Length=483, Percent_Identity=26.9151138716356, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71992392, Length=373, Percent_Identity=28.686327077748, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17556096, Length=184, Percent_Identity=27.1739130434783, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320023, Length=477, Percent_Identity=35.6394129979036, Blast_Score=313, Evalue=4e-86,
Organism=Saccharomyces cerevisiae, GI6320764, Length=474, Percent_Identity=32.7004219409283, Blast_Score=272, Evalue=7e-74,
Organism=Saccharomyces cerevisiae, GI6320027, Length=453, Percent_Identity=27.8145695364238, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI18921117, Length=463, Percent_Identity=36.7170626349892, Blast_Score=281, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24639277, Length=463, Percent_Identity=36.7170626349892, Blast_Score=281, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24639275, Length=463, Percent_Identity=36.7170626349892, Blast_Score=281, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24653753, Length=194, Percent_Identity=27.8350515463918, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 51324; Mature: 51324

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSDSFLDLCRAAIGSQNVLTDPADKAPYLTDWRRRYTGDALAVLRPGSTEEVAAVMRAC
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHH
HAHKLAVVPQGGNTGLCGGATPEPGDAAARGTVVLSLQRMNRVRQVDPLNNTITVEAGVI
HCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEEHHHHH
LQQLQEAAQTHGRLFPLSLAAEGSCTIGGNLSTNAGGTAVLRYGNTRELCLGLEVVNIKG
HHHHHHHHHHCCCEEEEEEECCCCEEECCCCCCCCCCEEEEEECCCCEEEEEEEEEEECC
EVWDGLRGLRKDNTGYDLRDLFIGAEGTLGIITAAVMKLFPAPRARVTALAAVESPRAAL
HHHHHHHHHCCCCCCCCHHHEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHH
ALLAIAQSHAGAMLTGFELMSAMCMDLVTKHYPQLRYPFTAHHPQLVLLELSDSESEEHA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHH
RTIFEKMMEVAFEAGVVKDAVVAESVQQSRDFWNLREHIPLAQVEEGKNIKHDIAVPISR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHCCHHH
VADFIETTDTLLQDAFPGARMVTFGHLGDGNLHYNVSPPVGVDHDQFLSHQDAINLIVHN
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHEEEEEEC
SVHVHNGSISAEHGLGQLKREENRRYKSEVELAMMRAIKQALDPQGLMNPGKVV
EEEEECCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MHSDSFLDLCRAAIGSQNVLTDPADKAPYLTDWRRRYTGDALAVLRPGSTEEVAAVMRAC
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHH
HAHKLAVVPQGGNTGLCGGATPEPGDAAARGTVVLSLQRMNRVRQVDPLNNTITVEAGVI
HCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEEHHHHH
LQQLQEAAQTHGRLFPLSLAAEGSCTIGGNLSTNAGGTAVLRYGNTRELCLGLEVVNIKG
HHHHHHHHHHCCCEEEEEEECCCCEEECCCCCCCCCCEEEEEECCCCEEEEEEEEEEECC
EVWDGLRGLRKDNTGYDLRDLFIGAEGTLGIITAAVMKLFPAPRARVTALAAVESPRAAL
HHHHHHHHHCCCCCCCCHHHEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHH
ALLAIAQSHAGAMLTGFELMSAMCMDLVTKHYPQLRYPFTAHHPQLVLLELSDSESEEHA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHH
RTIFEKMMEVAFEAGVVKDAVVAESVQQSRDFWNLREHIPLAQVEEGKNIKHDIAVPISR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHCCHHH
VADFIETTDTLLQDAFPGARMVTFGHLGDGNLHYNVSPPVGVDHDQFLSHQDAINLIVHN
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHEEEEEEC
SVHVHNGSISAEHGLGQLKREENRRYKSEVELAMMRAIKQALDPQGLMNPGKVV
EEEEECCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]