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The map label for this gene is cysS [H]

Identifier: 94310030

GI number: 94310030

Start: 1176601

End: 1178076

Strand: Direct

Name: cysS [H]

Synonym: Rmet_1085

Alternate gene names: 94310030

Gene position: 1176601-1178076 (Clockwise)

Preceding gene: 94310025

Following gene: 94310031

Centisome position: 29.95

GC content: 62.33

Gene sequence:

>1476_bases
ATGGGGCTCGCGCGCCATCGACATGCTTGTCAGCGCGCGGCAGTCTCGCTCGATGTCATCGACGCCGTATCCACTCACAT
CCGCTTCATGCAGCAATTGAACATCTACAACACGCTCGCGCGTGAAAAGCAGCCATTCGTGCCCATCGAACCCGGCAAGG
TCCGCATGTATGTGTGCGGCATGACCGTGTACGACTACTGTCACGTTGGCCATGCGCGGGTGATGGTGGTGTTCGATATG
GTGCACCGCTGGCTGCGCGCCGCCGGGTACGACGTGACGTACGTCCAGAACATCACTGATATCGATGACAAGATCATTCG
TCGCGCCGCGGAGAACGGCGAGACGATCGGTCAGCTCACCACGCGTTTCATCCAGTACATGCACGAGGATGCCACGGCGC
TGGGCGTGATCCGTCCCGACTATGAGCCGCGCGCGACCGAATACGTGCCGCAGATGCTCAATATCATCGAGAAACTCGAA
GCCAAGGGCCTGGCCTACCAGGCGACGGACGGCGACGTGAACTACTCGGTGCGCAAGTTCCCGGGCTACGGCAAGCTGTC
GGGCAAGTCGCTGGAAGATCTGCGCGCCGGCGAGCGCGTCAATGCCAACGATGCCAAGCAGGATCCGCTCGACTTCGTAC
TGTGGAAGTCGGCCAAGGCAACCGAGCCGCCCGAAAGCAAGTGGGACTCGAAGTGGGGCAGCGGCCGTCCGGGCTGGCAT
ATCGAATGCTCGGCCATGAGCTGCACGCTGCTCGGTGAGCATTTCGATATTCACGGCGGCGGCGCGGACCTGCAGTTCCC
GCACCACGAGAACGAGATCGCGCAATCGGAAGGGGCTTCCGGCAGGCCGTTCGTCAATATGTGGATGCACAACGGTTTCG
TGCGTGTGAATGACGAGAAGATGTCGAAATCGCTCGGCAACTTCTTCACGATCCGCGACGTGCTGAAGGAGTACGACGCC
GAAGTGGTGCGCTTCTTCATCCTGCGCGCGCACTATCGGAGCCCGCTGAACTATAGCGATGCCCACCTTGATGACGCACG
CCACGCACTGACGCGCCTGTATACAGCGCTCAAGGAAACGCAGCCCGGCGGTTGCGCGGTGGATTGGGAAGAGTCTCACG
CGAAGCGCTTTGCCGAAGCGATGAACGACGACTTCAACACGCCAATCGCCATGTCGGTGCTGTTCGACCTGGCCAGCGAG
GTCAATCGCACCGGTTCCGTGGCCGCGGCGCATCAACTCAAGGCGCTCGGCGGCACGCTGGGTCTGCTTGAGCGCGATCC
GCACACGTTCCTGCAAGGTGGTCATGTCGCCGGCAGCCTGAGCGGCGAGCAGATCGAAGCGCAGATCGCGGCCCGCCGTG
CGGCCAAGGCCGCGCGCAATTTCGCCGAGGCCGACCGCATTCGCGCCGAATTGCTCGAAGCCGGCGTGGTGCTGGAAGAC
AAGCCAGGTGGTGCCACCGAGTGGAGGCGTGCTTGA

Upstream 100 bases:

>100_bases
CGGCATTCTAACAAAGCGGCGGGGCGTGGAGCACAGGTCGCAAGTTCGCGTGACATTGTCGGCAGCGCGTCCGGCCGCCG
TTGATGGCTTCCGGTAAGAT

Downstream 100 bases:

>100_bases
ACGCTGCCGCGCGCAAGCCGAAGGCGGTTGCACCTGCCCAGCCGAAGCCGGTGGCGGGGAAGGCTGCCGCCAAGGTCGCG
CCAAAGGCCGGCGGCAAGCC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MGLARHRHACQRAAVSLDVIDAVSTHIRFMQQLNIYNTLAREKQPFVPIEPGKVRMYVCGMTVYDYCHVGHARVMVVFDM
VHRWLRAAGYDVTYVQNITDIDDKIIRRAAENGETIGQLTTRFIQYMHEDATALGVIRPDYEPRATEYVPQMLNIIEKLE
AKGLAYQATDGDVNYSVRKFPGYGKLSGKSLEDLRAGERVNANDAKQDPLDFVLWKSAKATEPPESKWDSKWGSGRPGWH
IECSAMSCTLLGEHFDIHGGGADLQFPHHENEIAQSEGASGRPFVNMWMHNGFVRVNDEKMSKSLGNFFTIRDVLKEYDA
EVVRFFILRAHYRSPLNYSDAHLDDARHALTRLYTALKETQPGGCAVDWEESHAKRFAEAMNDDFNTPIAMSVLFDLASE
VNRTGSVAAAHQLKALGGTLGLLERDPHTFLQGGHVAGSLSGEQIEAQIAARRAAKAARNFAEADRIRAELLEAGVVLED
KPGGATEWRRA

Sequences:

>Translated_491_residues
MGLARHRHACQRAAVSLDVIDAVSTHIRFMQQLNIYNTLAREKQPFVPIEPGKVRMYVCGMTVYDYCHVGHARVMVVFDM
VHRWLRAAGYDVTYVQNITDIDDKIIRRAAENGETIGQLTTRFIQYMHEDATALGVIRPDYEPRATEYVPQMLNIIEKLE
AKGLAYQATDGDVNYSVRKFPGYGKLSGKSLEDLRAGERVNANDAKQDPLDFVLWKSAKATEPPESKWDSKWGSGRPGWH
IECSAMSCTLLGEHFDIHGGGADLQFPHHENEIAQSEGASGRPFVNMWMHNGFVRVNDEKMSKSLGNFFTIRDVLKEYDA
EVVRFFILRAHYRSPLNYSDAHLDDARHALTRLYTALKETQPGGCAVDWEESHAKRFAEAMNDDFNTPIAMSVLFDLASE
VNRTGSVAAAHQLKALGGTLGLLERDPHTFLQGGHVAGSLSGEQIEAQIAARRAAKAARNFAEADRIRAELLEAGVVLED
KPGGATEWRRA
>Mature_490_residues
GLARHRHACQRAAVSLDVIDAVSTHIRFMQQLNIYNTLAREKQPFVPIEPGKVRMYVCGMTVYDYCHVGHARVMVVFDMV
HRWLRAAGYDVTYVQNITDIDDKIIRRAAENGETIGQLTTRFIQYMHEDATALGVIRPDYEPRATEYVPQMLNIIEKLEA
KGLAYQATDGDVNYSVRKFPGYGKLSGKSLEDLRAGERVNANDAKQDPLDFVLWKSAKATEPPESKWDSKWGSGRPGWHI
ECSAMSCTLLGEHFDIHGGGADLQFPHHENEIAQSEGASGRPFVNMWMHNGFVRVNDEKMSKSLGNFFTIRDVLKEYDAE
VVRFFILRAHYRSPLNYSDAHLDDARHALTRLYTALKETQPGGCAVDWEESHAKRFAEAMNDDFNTPIAMSVLFDLASEV
NRTGSVAAAHQLKALGGTLGLLERDPHTFLQGGHVAGSLSGEQIEAQIAARRAAKAARNFAEADRIRAELLEAGVVLEDK
PGGATEWRRA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=387, Percent_Identity=39.2764857881137, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI303304987, Length=234, Percent_Identity=42.3076923076923, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI62240992, Length=234, Percent_Identity=42.3076923076923, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI10835051, Length=234, Percent_Identity=42.3076923076923, Blast_Score=179, Evalue=8e-45,
Organism=Homo sapiens, GI21269877, Length=234, Percent_Identity=42.3076923076923, Blast_Score=178, Evalue=8e-45,
Organism=Escherichia coli, GI1786737, Length=468, Percent_Identity=55.5555555555556, Blast_Score=497, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17509795, Length=236, Percent_Identity=40.2542372881356, Blast_Score=175, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17509797, Length=236, Percent_Identity=40.2542372881356, Blast_Score=175, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6324082, Length=339, Percent_Identity=31.2684365781711, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI19922218, Length=388, Percent_Identity=36.8556701030928, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI19922364, Length=350, Percent_Identity=35.4285714285714, Blast_Score=175, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 54918; Mature: 54786

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLARHRHACQRAAVSLDVIDAVSTHIRFMQQLNIYNTLAREKQPFVPIEPGKVRMYVCG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
MTVYDYCHVGHARVMVVFDMVHRWLRAAGYDVTYVQNITDIDDKIIRRAAENGETIGQLT
CHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHH
TRFIQYMHEDATALGVIRPDYEPRATEYVPQMLNIIEKLEAKGLAYQATDGDVNYSVRKF
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEC
PGYGKLSGKSLEDLRAGERVNANDAKQDPLDFVLWKSAKATEPPESKWDSKWGSGRPGWH
CCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHCCCCCCCCCCCCE
IECSAMSCTLLGEHFDIHGGGADLQFPHHENEIAQSEGASGRPFVNMWMHNGFVRVNDEK
EEECCEEEEEECCCEEECCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCEEEECHHH
MSKSLGNFFTIRDVLKEYDAEVVRFFILRAHYRSPLNYSDAHLDDARHALTRLYTALKET
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHC
QPGGCAVDWEESHAKRFAEAMNDDFNTPIAMSVLFDLASEVNRTGSVAAAHQLKALGGTL
CCCCCEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHH
GLLERDPHTFLQGGHVAGSLSGEQIEAQIAARRAAKAARNFAEADRIRAELLEAGVVLED
HHCCCCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
KPGGATEWRRA
CCCCCCCCCCC
>Mature Secondary Structure 
GLARHRHACQRAAVSLDVIDAVSTHIRFMQQLNIYNTLAREKQPFVPIEPGKVRMYVCG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
MTVYDYCHVGHARVMVVFDMVHRWLRAAGYDVTYVQNITDIDDKIIRRAAENGETIGQLT
CHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCHHHHHHH
TRFIQYMHEDATALGVIRPDYEPRATEYVPQMLNIIEKLEAKGLAYQATDGDVNYSVRKF
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEC
PGYGKLSGKSLEDLRAGERVNANDAKQDPLDFVLWKSAKATEPPESKWDSKWGSGRPGWH
CCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHCCCCCCCCCCCCE
IECSAMSCTLLGEHFDIHGGGADLQFPHHENEIAQSEGASGRPFVNMWMHNGFVRVNDEK
EEECCEEEEEECCCEEECCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCEEEECHHH
MSKSLGNFFTIRDVLKEYDAEVVRFFILRAHYRSPLNYSDAHLDDARHALTRLYTALKET
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHC
QPGGCAVDWEESHAKRFAEAMNDDFNTPIAMSVLFDLASEVNRTGSVAAAHQLKALGGTL
CCCCCEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHH
GLLERDPHTFLQGGHVAGSLSGEQIEAQIAARRAAKAARNFAEADRIRAELLEAGVVLED
HHCCCCCHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
KPGGATEWRRA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA