Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 94309914

GI number: 94309914

Start: 1053204

End: 1054145

Strand: Direct

Name: nahR [H]

Synonym: Rmet_0969

Alternate gene names: 94309914

Gene position: 1053204-1054145 (Clockwise)

Preceding gene: 94309911

Following gene: 94309915

Centisome position: 26.81

GC content: 69.0

Gene sequence:

>942_bases
ATGCAGCTCAGCCGGATCGATCTCAATCTCTTCGTAGTATTCGACGCCATCTACAGCGAGGGGAGCATCACCGCTGCCGC
GCGCCAGTTGAACCTGACGCAGCCGGCCGTGAGCCACGCGCTGGGCCGGCTGCGCACGCTGTTCGACGATCCGCTGTTCG
AGCGCCGGGGGCAGGGCATGGCGCCGACGCCGCTGGCCCGTTCGTTGGCCGGGGAGGTGCGTGGGGCGTTGCAGTCCTTC
GCCCGGACGCTGCAGGACACGCCGCACTTCGACCCCACCAACACCACGCGCCGGTTCACCATCGGCATGCGCGACGCGCT
CGAGTCCACGCTGCTGCCGCCGCTGATGGCGCGCGTGACCGCGATGGCGCCGCACGTGGAGATTGCGGCGATTCGCTTCG
ACCGGCGCGAGATGGAGTCCGAGCTGCTGGCCGGCACGCTGGACGCCGCGATCGACATCCTGCTGCCGGTATCGCCGGCG
ATCCATCACGCCGCGTTCATGTCCGATCCGATGGTGGTGCTGGCGCGGCGCGATCATCCGCTGGTCAAGAAGGAGCTGAC
GCTCGAGCGCTATCTCGCGGCCGAGCACGTGCACGTGTCCTCGCGGCGGCGAGGCGCGGGGCTGGAGGACCAGGCGCTGC
ATCGCATGGGCCTGACGCGGCGGGTGCGCCTGCGTTGCCAGCACTATGCAGCCGCGTGCCGGGTGGTCAGTTGCACCGAT
CTGCTGGCCACGCTGCCGCTGCGCTACGCGCGCATCGCCAACGAGCCCTATGCCAACCGCCTGCTGTCGCTGCCGTTCAA
GGTGCCGTCGCTCGAACTGCATCTGTACTGGCACGCGGGCGGCGAGAACGACGGCGCGAACCGCTGGCTGCGCGAGCAGC
TGATGACGGTGATGGAATCGCTCGGCAGTGGCATGACGGATGTCACGTCGGCTGCCGAGTAA

Upstream 100 bases:

>100_bases
AAACTGACGTCGTGTCGATCGGTTGCCGGCTGGCCCCAATGCCCGCTGCGCGATCTGGCGTGCGTCTCGTGCCAGTCAAG
CATTCGCGCAGGAAGGTGCC

Downstream 100 bases:

>100_bases
CCCCGGGTTAACGTTGTCAGACAAACGCCGATTTCAACAGCGGGTGTGATCGCCAAGAATCGCCGGATCTTCTCGACAGG
AGGGACGGCATGGCTGACAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MQLSRIDLNLFVVFDAIYSEGSITAAARQLNLTQPAVSHALGRLRTLFDDPLFERRGQGMAPTPLARSLAGEVRGALQSF
ARTLQDTPHFDPTNTTRRFTIGMRDALESTLLPPLMARVTAMAPHVEIAAIRFDRREMESELLAGTLDAAIDILLPVSPA
IHHAAFMSDPMVVLARRDHPLVKKELTLERYLAAEHVHVSSRRRGAGLEDQALHRMGLTRRVRLRCQHYAAACRVVSCTD
LLATLPLRYARIANEPYANRLLSLPFKVPSLELHLYWHAGGENDGANRWLREQLMTVMESLGSGMTDVTSAAE

Sequences:

>Translated_313_residues
MQLSRIDLNLFVVFDAIYSEGSITAAARQLNLTQPAVSHALGRLRTLFDDPLFERRGQGMAPTPLARSLAGEVRGALQSF
ARTLQDTPHFDPTNTTRRFTIGMRDALESTLLPPLMARVTAMAPHVEIAAIRFDRREMESELLAGTLDAAIDILLPVSPA
IHHAAFMSDPMVVLARRDHPLVKKELTLERYLAAEHVHVSSRRRGAGLEDQALHRMGLTRRVRLRCQHYAAACRVVSCTD
LLATLPLRYARIANEPYANRLLSLPFKVPSLELHLYWHAGGENDGANRWLREQLMTVMESLGSGMTDVTSAAE
>Mature_313_residues
MQLSRIDLNLFVVFDAIYSEGSITAAARQLNLTQPAVSHALGRLRTLFDDPLFERRGQGMAPTPLARSLAGEVRGALQSF
ARTLQDTPHFDPTNTTRRFTIGMRDALESTLLPPLMARVTAMAPHVEIAAIRFDRREMESELLAGTLDAAIDILLPVSPA
IHHAAFMSDPMVVLARRDHPLVKKELTLERYLAAEHVHVSSRRRGAGLEDQALHRMGLTRRVRLRCQHYAAACRVVSCTD
LLATLPLRYARIANEPYANRLLSLPFKVPSLELHLYWHAGGENDGANRWLREQLMTVMESLGSGMTDVTSAAE

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=296, Percent_Identity=30.4054054054054, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87081766, Length=270, Percent_Identity=28.1481481481481, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=25.8278145695364, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1786820, Length=284, Percent_Identity=25, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787601, Length=250, Percent_Identity=24, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34848; Mature: 34848

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSRIDLNLFVVFDAIYSEGSITAAARQLNLTQPAVSHALGRLRTLFDDPLFERRGQGM
CCCEEEEEEEEEEEEHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCC
APTPLARSLAGEVRGALQSFARTLQDTPHFDPTNTTRRFTIGMRDALESTLLPPLMARVT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHCCHHHHHHHH
AMAPHVEIAAIRFDRREMESELLAGTLDAAIDILLPVSPAIHHAAFMSDPMVVLARRDHP
HHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEECCCC
LVKKELTLERYLAAEHVHVSSRRRGAGLEDQALHRMGLTRRVRLRCQHYAAACRVVSCTD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LLATLPLRYARIANEPYANRLLSLPFKVPSLELHLYWHAGGENDGANRWLREQLMTVMES
HHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
LGSGMTDVTSAAE
HCCCCHHHHHCCC
>Mature Secondary Structure
MQLSRIDLNLFVVFDAIYSEGSITAAARQLNLTQPAVSHALGRLRTLFDDPLFERRGQGM
CCCEEEEEEEEEEEEHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCC
APTPLARSLAGEVRGALQSFARTLQDTPHFDPTNTTRRFTIGMRDALESTLLPPLMARVT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHCCHHHHHHHH
AMAPHVEIAAIRFDRREMESELLAGTLDAAIDILLPVSPAIHHAAFMSDPMVVLARRDHP
HHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEECCCC
LVKKELTLERYLAAEHVHVSSRRRGAGLEDQALHRMGLTRRVRLRCQHYAAACRVVSCTD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LLATLPLRYARIANEPYANRLLSLPFKVPSLELHLYWHAGGENDGANRWLREQLMTVMES
HHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
LGSGMTDVTSAAE
HCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]