Click here to switch to the map view.

The map label for this gene is ureC [H]

Identifier: 94309906

GI number: 94309906

Start: 1045698

End: 1047416

Strand: Direct

Name: ureC [H]

Synonym: Rmet_0961

Alternate gene names: 94309906

Gene position: 1045698-1047416 (Clockwise)

Preceding gene: 94309905

Following gene: 94309907

Centisome position: 26.62

GC content: 64.81

Gene sequence:

>1719_bases
ATGAGCGTGAAGATCTCCAGGCAGGCCTATGCCGAGATGTTCGGCCCGACCACGGGCGACAGGTTGCGTCTTGCCGACAC
GGACCTTGTGATCGAAGTCGAGCGCGATTTCACGATCTACGGCGAGGAAGTGAAGTTCGGCGGCGGCAAGGTGATTCGCG
ATGGCATGGGCCAGAGCCAGCGCATGTCGAAGGACTGCGTCGACACGGTGGTCACCAACGCACTGATCATCGACCACTGG
GGCATCGTGAAGGCCGATATCGGGCTGAAGCACGGGCGCATCGCGGCAATCGGCAAGGCGGGTAATCCGGATATCCAGCC
GGGGGTGACGATCATCGTCGGGCCGGGTACCGAGGTCATCGCGGGCGAGGGGATGATTGTCACCGCTGGCGGCATCGACA
CGCACATCCACTTCATCTGCCCGCAGCAGATCGAAGAAGCGCTGATGAGCGGCGTGACGACGATGATCGGCGGCGGCACC
GGGCCGGCGACGGGCACCTATGCGACGACCGTGACGCCGGGCCCGTGGTACATGGAGCGGATGCTGCAGGCGGCCGATGC
GTATCCGATGAACATCGGCTTTCTCGGCAAGGGCAACGCCAGCCTGGCGGCGCCGCTGACCGAGCAGGTGGAGGCGGGCG
CCATCGGCTTGAAGCTGCACGAGGACTGGGGCACCACGCCGCAGGCGATCGACACCTGCCTGTCCGTGGCCGATGCCACC
GATACCCAAGTGGCGATCCACACCGATACGCTCAACGAAGGCGGTTTTGTCGAGGCGACGATTGCCGCGTTCAAGGGCCG
CACGATCCATACGTATCACACCGAGGGCGCGGGTGGCGGCCACGCGCCGGACATCATCAAGGTTTGCGGCGAGGCTAATG
TGCTGCCGTCGTCGACCAATCCGACGCGCCCGTACACCGTGAACACGCTGGACGAGCACCTGGACATGTTGATGGTCTGC
CATCACCTGGATCCGGCCATTGCGGAGGACATTGCGTTCGCCGAGTCGCGCATCCGTCGCGAGACCATCGCGGCCGAGGA
CATCCTGCATGACCTGGGCGCGTTCTCGATGATCTCGAGCGATTCGCAGGCCATGGGCCGCGTGGGCGAGGTGATCATTC
GCACGTGGCAGACCGCGCACAAGATGGCCGCGCAGCGCGGCAAGTTGCCCGGCGATCCACACGATGCGCGTGGCGGGCAC
GACAACTTCCGCGTCAAGCGCTATATCGCCAAGTACACGATCAATCCAGCGCTCACGCACGGTATCGCGCACGAGGTGGG
GTCGATCGAAGTCGGCAAGTGGGCGGATCTGGTGTTCTGGAAGCCGGCCTTCTTCGGCGTGAAGCCGAGCCTGATTCTCA
AGGGCGGCATGATCGCGGCGGCGGCGATGGGCGATCCGAATGCCTCGATCCCGACACCGCAGCCGGTGCACTATCGTCCG
ATGTTCGCTTCGGCCGGCGGGGCGCTGCCGAGATCGTCGCTCACCTTCGTCTCGCAGGCGGCGCTGGCGGCGAATGTCGG
CGAGCGCTATGGCCTGGCCAAGACGCTCACCGCAGTGCGCGGCACGCGTACCGTCAGCAAACGCGACATGGTGCACAATG
ACTGGCAGCCGCACGTCACCGTGGATCCGGAGACTTACCAGGTGGTAGCCGATGGTCAGCTGCTGACGTGCGAACCTGCC
ACTGTGCTGCCGATGGCGCAGCGCTATTTCCTGTTCTGA

Upstream 100 bases:

>100_bases
TGCGCTTCGAGCCGGGGCAGTCGCGCACGGTACAACTCGTGGCGCTGGACGGTGACCGCATCGTCTATGGTTTCAACGGC
AGAATCATGGGAGCACTCTG

Downstream 100 bases:

>100_bases
CCCGTGATCAAGATCGACAAACACCTGCCCGCTCCGCACGGCATCGCGCCGGTACTCGTGCGCCGCGCGCCGAAGCTCGT
CCTGCCGTTCGGCGAACGCA

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MSVKISRQAYAEMFGPTTGDRLRLADTDLVIEVERDFTIYGEEVKFGGGKVIRDGMGQSQRMSKDCVDTVVTNALIIDHW
GIVKADIGLKHGRIAAIGKAGNPDIQPGVTIIVGPGTEVIAGEGMIVTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGT
GPATGTYATTVTPGPWYMERMLQAADAYPMNIGFLGKGNASLAAPLTEQVEAGAIGLKLHEDWGTTPQAIDTCLSVADAT
DTQVAIHTDTLNEGGFVEATIAAFKGRTIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTRPYTVNTLDEHLDMLMVC
HHLDPAIAEDIAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVIIRTWQTAHKMAAQRGKLPGDPHDARGGH
DNFRVKRYIAKYTINPALTHGIAHEVGSIEVGKWADLVFWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRP
MFASAGGALPRSSLTFVSQAALAANVGERYGLAKTLTAVRGTRTVSKRDMVHNDWQPHVTVDPETYQVVADGQLLTCEPA
TVLPMAQRYFLF

Sequences:

>Translated_572_residues
MSVKISRQAYAEMFGPTTGDRLRLADTDLVIEVERDFTIYGEEVKFGGGKVIRDGMGQSQRMSKDCVDTVVTNALIIDHW
GIVKADIGLKHGRIAAIGKAGNPDIQPGVTIIVGPGTEVIAGEGMIVTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGT
GPATGTYATTVTPGPWYMERMLQAADAYPMNIGFLGKGNASLAAPLTEQVEAGAIGLKLHEDWGTTPQAIDTCLSVADAT
DTQVAIHTDTLNEGGFVEATIAAFKGRTIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTRPYTVNTLDEHLDMLMVC
HHLDPAIAEDIAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVIIRTWQTAHKMAAQRGKLPGDPHDARGGH
DNFRVKRYIAKYTINPALTHGIAHEVGSIEVGKWADLVFWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRP
MFASAGGALPRSSLTFVSQAALAANVGERYGLAKTLTAVRGTRTVSKRDMVHNDWQPHVTVDPETYQVVADGQLLTCEPA
TVLPMAQRYFLF
>Mature_571_residues
SVKISRQAYAEMFGPTTGDRLRLADTDLVIEVERDFTIYGEEVKFGGGKVIRDGMGQSQRMSKDCVDTVVTNALIIDHWG
IVKADIGLKHGRIAAIGKAGNPDIQPGVTIIVGPGTEVIAGEGMIVTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTG
PATGTYATTVTPGPWYMERMLQAADAYPMNIGFLGKGNASLAAPLTEQVEAGAIGLKLHEDWGTTPQAIDTCLSVADATD
TQVAIHTDTLNEGGFVEATIAAFKGRTIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTRPYTVNTLDEHLDMLMVCH
HLDPAIAEDIAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVIIRTWQTAHKMAAQRGKLPGDPHDARGGHD
NFRVKRYIAKYTINPALTHGIAHEVGSIEVGKWADLVFWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRPM
FASAGGALPRSSLTFVSQAALAANVGERYGLAKTLTAVRGTRTVSKRDMVHNDWQPHVTVDPETYQVVADGQLLTCEPAT
VLPMAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 61138; Mature: 61007

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS01120 UREASE_1 ; PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKISRQAYAEMFGPTTGDRLRLADTDLVIEVERDFTIYGEEVKFGGGKVIRDGMGQSQ
CCEEECHHHHHHHHCCCCCCEEEEECCCEEEEEECCEEEECCEEEECCCEEEECCCCCHH
RMSKDCVDTVVTNALIIDHWGIVKADIGLKHGRIAAIGKAGNPDIQPGVTIIVGPGTEVI
HHHHHHHHHHHHCEEEEECCCEEEECCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCEE
AGEGMIVTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGPATGTYATTVTPGPWYMER
ECCCEEEEECCCCEEEEEECHHHHHHHHHHCHHHHHCCCCCCCCCCEEEEECCCHHHHHH
MLQAADAYPMNIGFLGKGNASLAAPLTEQVEAGAIGLKLHEDWGTTPQAIDTCLSVADAT
HHHHHCCCCCEEEEEECCCCCEECCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCC
DTQVAIHTDTLNEGGFVEATIAAFKGRTIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTN
CCEEEEEECCCCCCCEEEEEHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCC
PTRPYTVNTLDEHLDMLMVCHHLDPAIAEDIAFAESRIRRETIAAEDILHDLGAFSMISS
CCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSQAMGRVGEVIIRTWQTAHKMAAQRGKLPGDPHDARGGHDNFRVKRYIAKYTINPALTH
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEEHHHEECCHHHHH
GIAHEVGSIEVGKWADLVFWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRP
HHHHHCCCEECCCCEEEEEECCHHHCCCHHHEEECCEEEEEECCCCCCCCCCCCCCEECC
MFASAGGALPRSSLTFVSQAALAANVGERYGLAKTLTAVRGTRTVSKRDMVHNDWQPHVT
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHCCCCCCCEE
VDPETYQVVADGQLLTCEPATVLPMAQRYFLF
ECCCEEEEEECCEEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
SVKISRQAYAEMFGPTTGDRLRLADTDLVIEVERDFTIYGEEVKFGGGKVIRDGMGQSQ
CEEECHHHHHHHHCCCCCCEEEEECCCEEEEEECCEEEECCEEEECCCEEEECCCCCHH
RMSKDCVDTVVTNALIIDHWGIVKADIGLKHGRIAAIGKAGNPDIQPGVTIIVGPGTEVI
HHHHHHHHHHHHCEEEEECCCEEEECCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCEE
AGEGMIVTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGPATGTYATTVTPGPWYMER
ECCCEEEEECCCCEEEEEECHHHHHHHHHHCHHHHHCCCCCCCCCCEEEEECCCHHHHHH
MLQAADAYPMNIGFLGKGNASLAAPLTEQVEAGAIGLKLHEDWGTTPQAIDTCLSVADAT
HHHHHCCCCCEEEEEECCCCCEECCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCC
DTQVAIHTDTLNEGGFVEATIAAFKGRTIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTN
CCEEEEEECCCCCCCEEEEEHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCC
PTRPYTVNTLDEHLDMLMVCHHLDPAIAEDIAFAESRIRRETIAAEDILHDLGAFSMISS
CCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSQAMGRVGEVIIRTWQTAHKMAAQRGKLPGDPHDARGGHDNFRVKRYIAKYTINPALTH
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEEHHHEECCHHHHH
GIAHEVGSIEVGKWADLVFWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRP
HHHHHCCCEECCCCEEEEEECCHHHCCCHHHEEECCEEEEEECCCCCCCCCCCCCCEECC
MFASAGGALPRSSLTFVSQAALAANVGERYGLAKTLTAVRGTRTVSKRDMVHNDWQPHVT
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHCCCCCCCEE
VDPETYQVVADGQLLTCEPATVLPMAQRYFLF
ECCCEEEEEECCEEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA