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The map label for this gene is nahR [H]

Identifier: 94309839

GI number: 94309839

Start: 981278

End: 982228

Strand: Direct

Name: nahR [H]

Synonym: Rmet_0894

Alternate gene names: 94309839

Gene position: 981278-982228 (Clockwise)

Preceding gene: 94309831

Following gene: 94309841

Centisome position: 24.98

GC content: 66.14

Gene sequence:

>951_bases
ATGCACGGACGCGACCATCTCGATACATATCTACTGCGGGTGCTTCACACACTGCTGACTGAGCAGAGCGTGACACGTAC
CGCCGTGCGCCTCGGCCAGTCGCAGCCCGCCATCAGCAACACGCTCAAGCGGCTGCGCGAGATCACCGGGGACGCCATTC
TGGTGCGCGGCAAGAGCGGCATGGTGCCCACCGAGCGCGGCCGCGAACTGCTGCTGCTGGCCGAGCAGAGTCTGGCCGCG
ATGGATCGCATCGCCCGCCCCCCGCAGCAGTTCGATCCCGCCACCACCACGCGGACGTTCCACCTTGGGGCGCCCGACTA
TCTTGACGCGTTCTTCCTGCCGAATATCGTCGAGCGCGTGCGGCGGCTTGCGCCGGGCGCGAAGCTGTTCGTCCACCCGA
TGACGCAGTCGACCGACTTTCTGGATGCGCTGGAGCAGGGCCATCTCGATATCGTGGTCGGCAACTGGCTGTCGCCGCCC
GAGCATCTGCATATCTCGCCGCTGTTCGATGACGAGGTCGTCTGTATGCTCGGCGCGCAGCACCCGCTGGCGCGTCACGG
GCTGACGCTGCGCCACTACCTGGAAATGCCGCATCTGGCGCCGGCGCCGTATGCGTCGATGCAGCGCAGCATGATCGACC
AGGCGCTGGCGGAGCAGGGCTACAAGCGGAATATTCAGGTCACGCTGCCGTACTTCGGGCTGGTGCCCTACGTGCTGATG
AAGACGGACATGGTGTTCACCACGGGCCGGCAGTTTGCCGCGCATTACGCGCAGTACCTGCCGATCCGCATGGTGCCGTC
ACCGGTGCAGTTCCCGCGCATGCGCTTCTACCAGCTCTGGCACGAGCGTTGCCATGCGGCGCCGGACGTGATGTGGATGC
GGCGGATGATTGCCGAGGTCGCGACGGATCTGCCACAGCTTCCACGGCTGGAGGCCACCGGGGCGGGCTGA

Upstream 100 bases:

>100_bases
TGCCGGATTTGACCGTTTCGGGGGTGGCTGTCTTACACTATGCGCCGTTCCCATCCCCCACGCCACCCACGCCAAGCCAT
ATGGCGGGCTGGCACCTGCC

Downstream 100 bases:

>100_bases
GTCCGGCGCCCCCGTGGTTATGCCGGGACTTCCGCGCCGTCCCGGCTTCGGTTGCGTCGCCTGGTTACTTTGCCTTGTAG
TCGGGGAAGAAGAGTTGTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MHGRDHLDTYLLRVLHTLLTEQSVTRTAVRLGQSQPAISNTLKRLREITGDAILVRGKSGMVPTERGRELLLLAEQSLAA
MDRIARPPQQFDPATTTRTFHLGAPDYLDAFFLPNIVERVRRLAPGAKLFVHPMTQSTDFLDALEQGHLDIVVGNWLSPP
EHLHISPLFDDEVVCMLGAQHPLARHGLTLRHYLEMPHLAPAPYASMQRSMIDQALAEQGYKRNIQVTLPYFGLVPYVLM
KTDMVFTTGRQFAAHYAQYLPIRMVPSPVQFPRMRFYQLWHERCHAAPDVMWMRRMIAEVATDLPQLPRLEATGAG

Sequences:

>Translated_316_residues
MHGRDHLDTYLLRVLHTLLTEQSVTRTAVRLGQSQPAISNTLKRLREITGDAILVRGKSGMVPTERGRELLLLAEQSLAA
MDRIARPPQQFDPATTTRTFHLGAPDYLDAFFLPNIVERVRRLAPGAKLFVHPMTQSTDFLDALEQGHLDIVVGNWLSPP
EHLHISPLFDDEVVCMLGAQHPLARHGLTLRHYLEMPHLAPAPYASMQRSMIDQALAEQGYKRNIQVTLPYFGLVPYVLM
KTDMVFTTGRQFAAHYAQYLPIRMVPSPVQFPRMRFYQLWHERCHAAPDVMWMRRMIAEVATDLPQLPRLEATGAG
>Mature_316_residues
MHGRDHLDTYLLRVLHTLLTEQSVTRTAVRLGQSQPAISNTLKRLREITGDAILVRGKSGMVPTERGRELLLLAEQSLAA
MDRIARPPQQFDPATTTRTFHLGAPDYLDAFFLPNIVERVRRLAPGAKLFVHPMTQSTDFLDALEQGHLDIVVGNWLSPP
EHLHISPLFDDEVVCMLGAQHPLARHGLTLRHYLEMPHLAPAPYASMQRSMIDQALAEQGYKRNIQVTLPYFGLVPYVLM
KTDMVFTTGRQFAAHYAQYLPIRMVPSPVQFPRMRFYQLWHERCHAAPDVMWMRRMIAEVATDLPQLPRLEATGAG

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=303, Percent_Identity=26.7326732673267, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790147, Length=304, Percent_Identity=25.6578947368421, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081904, Length=253, Percent_Identity=26.8774703557312, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789506, Length=297, Percent_Identity=22.2222222222222, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35883; Mature: 35883

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGRDHLDTYLLRVLHTLLTEQSVTRTAVRLGQSQPAISNTLKRLREITGDAILVRGKSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCC
MVPTERGRELLLLAEQSLAAMDRIARPPQQFDPATTTRTFHLGAPDYLDAFFLPNIVERV
CCCCCCCCEEEEEHHHHHHHHHHHCCCCHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
RRLAPGAKLFVHPMTQSTDFLDALEQGHLDIVVGNWLSPPEHLHISPLFDDEVVCMLGAQ
HHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCEEECCCCCCCCCEEECCC
HPLARHGLTLRHYLEMPHLAPAPYASMQRSMIDQALAEQGYKRNIQVTLPYFGLVPYVLM
CCHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHH
KTDMVFTTGRQFAAHYAQYLPIRMVPSPVQFPRMRFYQLWHERCHAAPDVMWMRRMIAEV
HHHHHHHCHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ATDLPQLPRLEATGAG
HHCCCCCCCCCCCCCC
>Mature Secondary Structure
MHGRDHLDTYLLRVLHTLLTEQSVTRTAVRLGQSQPAISNTLKRLREITGDAILVRGKSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCC
MVPTERGRELLLLAEQSLAAMDRIARPPQQFDPATTTRTFHLGAPDYLDAFFLPNIVERV
CCCCCCCCEEEEEHHHHHHHHHHHCCCCHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
RRLAPGAKLFVHPMTQSTDFLDALEQGHLDIVVGNWLSPPEHLHISPLFDDEVVCMLGAQ
HHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCEEECCCCCCCCCEEECCC
HPLARHGLTLRHYLEMPHLAPAPYASMQRSMIDQALAEQGYKRNIQVTLPYFGLVPYVLM
CCHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHH
KTDMVFTTGRQFAAHYAQYLPIRMVPSPVQFPRMRFYQLWHERCHAAPDVMWMRRMIAEV
HHHHHHHCHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ATDLPQLPRLEATGAG
HHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]