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The map label for this gene is ugd [H]

Identifier: 94309671

GI number: 94309671

Start: 803084

End: 804457

Strand: Direct

Name: ugd [H]

Synonym: Rmet_0726

Alternate gene names: 94309671

Gene position: 803084-804457 (Clockwise)

Preceding gene: 94309670

Following gene: 94309672

Centisome position: 20.44

GC content: 62.23

Gene sequence:

>1374_bases
ATGAAAGTCACGATTATCGGTAGCGGCTATGTCGGTCTGGTGACCGGCGCCTGTCTGGCCGAACTCGGCAACTCCGTGTT
CTGCCTCGATGTCGACGAAAAGAAGATCGCGCTGCTGAATGCCGGCGGCGTGCCGATCTACGAACCAGGCCTGAAAGAGC
TGATTGACCGCAACCGTGCGGCCGGCCGCCTGACGTTCTCGACCGATGTTGCCGCCAGCGTCGAACATGCCGACGTACAG
TTCATCGCCGTGGGTACCCCGCCGGACGAAGACGGCTCGGCGGATCTGAAGTACGTGCTGGCAGCGGCCCGCAATATCGG
CCGGCATATGACCGGCTTCAAGGTGGTGGTGGACAAGTCGACCGTGCCGGTTGGCACGGGCGATCGCGTCAGCGCCGTGA
TTCGCGAGGAACTGGCCGCGCGCGGTCTGGAAGACCTGCAGTTCTCGGTGGTATCGAACCCCGAGTTCCTGAAGGAAGGC
GCGGCCGTGGAAGACTTCATGCGTCCGGACCGTATCGTGCTGGGCTGCGCGCCCGACGTTGCGGGCCGCCATGCGCAGGC
GATCATGCGTCAGCTCTACTCGCCGTTCAATCGTAACCACGAGCGCACGTTCTATATGGATGTCCGTTCGGCCGAGTTCA
CCAAGTACGCCGCGAACTCGATGCTGGCCACGCGTATCTCCTTTATGAACGAGCTGGCCAATTTGGCCGACGAGGTCGGT
GCGGACATCGAACTCGTGCGCCTCGGCATCGGTTCGGATCCGCGTATTGGCTATAGCTTCCTGTACGCCGGCGCAGGCTA
TGGCGGTTCGTGCTTCCCGAAGGACGTGCAGGCGCTGATGCGCACGGCTAGCGCCCATGGCAAGCCGATGCGCGTGCTGG
AGGCCGTGGAGGCCGTCAACGATTCCCAGAAGCAGGTGCTTGGCGACAAGATCATCAAGCGATTTGGCGAGGATCTGACA
GGCAAGACGTTTGGCGTCTGGGGTCTGGCATTCAAGCCGAATACCGACGATATGCGCGAGGCGCCGTCCCGTGTGCTGGC
GCGTGAGATGATTTCGCGCGGCGCGTCGTTGCGCGTACACGATCCGGTGGCGATGGACGAGGCGCGTCGCGTGCTCGAGC
TCGATCTGGCCGATATTCCGGACGCCATGGCGCGCATCCAGTTCTGCAACGCCCAGATGGACGTGCTCAAGGATGCCGAC
GCACTCGTGATCGTGACCGAATGGAAGGTGTTCCGCAGCCCGGATTTCTCGCAAATTCGCAACATGCTCAAAACGCCTGT
CATTATTGATGGTCGTAATCTCTACGAACCCGATGCCATGGCCGAGGCCGGCATCGAGTACCACGCGATCGGGCGCTCGA
GCTCGGCGCACTGA

Upstream 100 bases:

>100_bases
CTGGGAAACGTATGCGCCACGCCGCTCCGAAGCGCTGGGCTAAGCCGCTACACGCAACGCCCCGGGCGATCAAGATCATT
ACTATTCTGGAGCTTCCGCA

Downstream 100 bases:

>100_bases
CCCGTTCAATCCGCGTATCCGTGAGAGCCCGATCGAGCCGCGTCCCAGTTGGGCGCGGCCAGGGCGCAAAGGGAAGTTCA
TGAGCAAGAACCCGATTTCG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKVTIIGSGYVGLVTGACLAELGNSVFCLDVDEKKIALLNAGGVPIYEPGLKELIDRNRAAGRLTFSTDVAASVEHADVQ
FIAVGTPPDEDGSADLKYVLAAARNIGRHMTGFKVVVDKSTVPVGTGDRVSAVIREELAARGLEDLQFSVVSNPEFLKEG
AAVEDFMRPDRIVLGCAPDVAGRHAQAIMRQLYSPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNELANLADEVG
ADIELVRLGIGSDPRIGYSFLYAGAGYGGSCFPKDVQALMRTASAHGKPMRVLEAVEAVNDSQKQVLGDKIIKRFGEDLT
GKTFGVWGLAFKPNTDDMREAPSRVLAREMISRGASLRVHDPVAMDEARRVLELDLADIPDAMARIQFCNAQMDVLKDAD
ALVIVTEWKVFRSPDFSQIRNMLKTPVIIDGRNLYEPDAMAEAGIEYHAIGRSSSAH

Sequences:

>Translated_457_residues
MKVTIIGSGYVGLVTGACLAELGNSVFCLDVDEKKIALLNAGGVPIYEPGLKELIDRNRAAGRLTFSTDVAASVEHADVQ
FIAVGTPPDEDGSADLKYVLAAARNIGRHMTGFKVVVDKSTVPVGTGDRVSAVIREELAARGLEDLQFSVVSNPEFLKEG
AAVEDFMRPDRIVLGCAPDVAGRHAQAIMRQLYSPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNELANLADEVG
ADIELVRLGIGSDPRIGYSFLYAGAGYGGSCFPKDVQALMRTASAHGKPMRVLEAVEAVNDSQKQVLGDKIIKRFGEDLT
GKTFGVWGLAFKPNTDDMREAPSRVLAREMISRGASLRVHDPVAMDEARRVLELDLADIPDAMARIQFCNAQMDVLKDAD
ALVIVTEWKVFRSPDFSQIRNMLKTPVIIDGRNLYEPDAMAEAGIEYHAIGRSSSAH
>Mature_457_residues
MKVTIIGSGYVGLVTGACLAELGNSVFCLDVDEKKIALLNAGGVPIYEPGLKELIDRNRAAGRLTFSTDVAASVEHADVQ
FIAVGTPPDEDGSADLKYVLAAARNIGRHMTGFKVVVDKSTVPVGTGDRVSAVIREELAARGLEDLQFSVVSNPEFLKEG
AAVEDFMRPDRIVLGCAPDVAGRHAQAIMRQLYSPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNELANLADEVG
ADIELVRLGIGSDPRIGYSFLYAGAGYGGSCFPKDVQALMRTASAHGKPMRVLEAVEAVNDSQKQVLGDKIIKRFGEDLT
GKTFGVWGLAFKPNTDDMREAPSRVLAREMISRGASLRVHDPVAMDEARRVLELDLADIPDAMARIQFCNAQMDVLKDAD
ALVIVTEWKVFRSPDFSQIRNMLKTPVIIDGRNLYEPDAMAEAGIEYHAIGRSSSAH

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=470, Percent_Identity=35.531914893617, Blast_Score=262, Evalue=4e-70,
Organism=Homo sapiens, GI296040438, Length=372, Percent_Identity=34.9462365591398, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI296040443, Length=321, Percent_Identity=34.5794392523364, Blast_Score=172, Evalue=4e-43,
Organism=Escherichia coli, GI1788340, Length=403, Percent_Identity=27.5434243176179, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI48994968, Length=454, Percent_Identity=27.5330396475771, Blast_Score=131, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17560350, Length=467, Percent_Identity=36.4025695931477, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI17136908, Length=465, Percent_Identity=33.5483870967742, Blast_Score=248, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49777; Mature: 49777

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTIIGSGYVGLVTGACLAELGNSVFCLDVDEKKIALLNAGGVPIYEPGLKELIDRNRA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHCCCC
AGRLTFSTDVAASVEHADVQFIAVGTPPDEDGSADLKYVLAAARNIGRHMTGFKVVVDKS
CCEEEEECCHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTGDRVSAVIREELAARGLEDLQFSVVSNPEFLKEGAAVEDFMRPDRIVLGCAPDV
CCCCCCCHHHHHHHHHHHHHCCHHHHEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCCC
AGRHAQAIMRQLYSPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNELANLADEVG
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADIELVRLGIGSDPRIGYSFLYAGAGYGGSCFPKDVQALMRTASAHGKPMRVLEAVEAVN
CCEEEEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
DSQKQVLGDKIIKRFGEDLTGKTFGVWGLAFKPNTDDMREAPSRVLAREMISRGASLRVH
CHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEC
DPVAMDEARRVLELDLADIPDAMARIQFCNAQMDVLKDADALVIVTEWKVFRSPDFSQIR
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHCCCCEEEEEEECHHHCCCCHHHHH
NMLKTPVIIDGRNLYEPDAMAEAGIEYHAIGRSSSAH
HHHCCCEEECCCCCCCCHHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure
MKVTIIGSGYVGLVTGACLAELGNSVFCLDVDEKKIALLNAGGVPIYEPGLKELIDRNRA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHCCCC
AGRLTFSTDVAASVEHADVQFIAVGTPPDEDGSADLKYVLAAARNIGRHMTGFKVVVDKS
CCEEEEECCHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTGDRVSAVIREELAARGLEDLQFSVVSNPEFLKEGAAVEDFMRPDRIVLGCAPDV
CCCCCCCHHHHHHHHHHHHHCCHHHHEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCCC
AGRHAQAIMRQLYSPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNELANLADEVG
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADIELVRLGIGSDPRIGYSFLYAGAGYGGSCFPKDVQALMRTASAHGKPMRVLEAVEAVN
CCEEEEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
DSQKQVLGDKIIKRFGEDLTGKTFGVWGLAFKPNTDDMREAPSRVLAREMISRGASLRVH
CHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEC
DPVAMDEARRVLELDLADIPDAMARIQFCNAQMDVLKDADALVIVTEWKVFRSPDFSQIR
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHCCCCEEEEEEECHHHCCCCHHHHH
NMLKTPVIIDGRNLYEPDAMAEAGIEYHAIGRSSSAH
HHHCCCEEECCCCCCCCHHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]