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The map label for this gene is aroA [H]

Identifier: 94309664

GI number: 94309664

Start: 796526

End: 797884

Strand: Direct

Name: aroA [H]

Synonym: Rmet_0719

Alternate gene names: 94309664

Gene position: 796526-797884 (Clockwise)

Preceding gene: 94309663

Following gene: 94309666

Centisome position: 20.28

GC content: 64.46

Gene sequence:

>1359_bases
ATGCCGCCAGCGCGCGCGGCGCGCAACGGCCATGCTGCAGAAAACATGGAACAACTGACCCTCGGCCCCCTGACCCGTGC
TTCCGGCACGGTGCGCCTGCCCGGCTCCAAGAGCATCTCCAACCGCGTGCTGCTGCTGTCCGCGCTCGCCACCGGCGAAA
CGCGCGTCCGCGACCTGCTCGATTCCGACGACACGCGTGTCATGCTCGAAGCGCTCAAGGTGCTCGGCGTGGCATGGCGG
CGCGAGGGCAACGACTGCATCGTGTCCGGCGTGGGCGGAAATTTCCCGAGCAAGGCGGCAGACCTGTTCATGGGTAATGC
CGGCACGGCAATCCGGCCATTGACCGCGGCACTGGCGCTGCAAGGCGGTACGTACAAGCTGAGCGGCGTGCAGCGGATGC
ATGAACGGCCGATCGGCGATCTGGTCGATGGCCTGCGGCAGGTCGGCGCATCGGTGGATTACCTGGGCACGCCCGGCTAC
CCGCCTTTGCAGATCAACCCAGCGCAGATTCGCATTGATGCACCGATCCGTGTGCGCGGCGATGTATCGAGCCAGTTCCT
GACCGCGCTGTTGATGACGTTGCCAATGGCCCAGGCACAATCGGGTCGCATTGAGATCGAAGTGGTCGGCGAATTGATTT
CGAAGCCGTATATCGAGATCACGCTGAACTTGCTGTCGCGCTTCGGTATTGCCGTCGAGAGACAGGGCTGGGAGCGCTTT
ATCCTGCCGGCCGGCGCGCGGTACCGTTCGCCGGGCGAGATCTACGTCGAAGGCGATGCGTCCACGGCATCGTACTTCCT
GGCGGCGGGCGCCATCGGTGGTGGCCCGGTACGCGTGGAGGGTGTGGGCATGGCGAGTATCCAGGGCGATGTTCGGTTTG
CCGATGCGCTGAACCGGATGGGCGCCAACGTGATGGCTGGTGACAACTGGATTGAAGTGCGCGGCACAGAGCGTGACGAC
GGCCGACTCAACGGCATCGAGCTCGACTGCAATCACATTCCTGATGCGGCGATGACGCTGGCCGTGGCCGCGCTGTTCGC
GGAGGGCACCACCACGCTGACCAACATCGCCAGCTGGCGGGTCAAGGAAACGGACCGCATCTCAGCGATGGCGACGGAGC
TGCGCAAGCTCGGCGCGGAGGTGGAGGAGGGGGCTGATTACCTGAAAGTGACGCCGCCGACCTCCCCGGCAACGTGGCAG
ACCCCGGATGCTGGAATTGGCACCTATGATGACCATCGGATGGCCATGTGTTTCTCGTTGGCCGCATTCGGCCCGTTGCC
CGTGAAGATCAACGACCCCGGCTGCGTGGCAAAGACGTTCCCCGAGTACTTCGAGGTATTTGCCGGAGTGGCGCGGTAA

Upstream 100 bases:

>100_bases
AAGGCGATGGCGCGGCGCTCGAACGGCTGTTCGCGCGTGCCAGCGACACACGCCTGAAATGGGGCGCCGCACGGACGGCT
GCCAACAACGTCGAACCCTG

Downstream 100 bases:

>100_bases
ACGGTCACTCAGCCCGGGAGGCCATGATCAGGCGGCGGCGTAACGGGCCGCCGTCGTTGCTTCGGGGGGTGCAGCAAGGG
TTTTGGCCTGGCGTTCGCGG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MPPARAARNGHAAENMEQLTLGPLTRASGTVRLPGSKSISNRVLLLSALATGETRVRDLLDSDDTRVMLEALKVLGVAWR
REGNDCIVSGVGGNFPSKAADLFMGNAGTAIRPLTAALALQGGTYKLSGVQRMHERPIGDLVDGLRQVGASVDYLGTPGY
PPLQINPAQIRIDAPIRVRGDVSSQFLTALLMTLPMAQAQSGRIEIEVVGELISKPYIEITLNLLSRFGIAVERQGWERF
ILPAGARYRSPGEIYVEGDASTASYFLAAGAIGGGPVRVEGVGMASIQGDVRFADALNRMGANVMAGDNWIEVRGTERDD
GRLNGIELDCNHIPDAAMTLAVAALFAEGTTTLTNIASWRVKETDRISAMATELRKLGAEVEEGADYLKVTPPTSPATWQ
TPDAGIGTYDDHRMAMCFSLAAFGPLPVKINDPGCVAKTFPEYFEVFAGVAR

Sequences:

>Translated_452_residues
MPPARAARNGHAAENMEQLTLGPLTRASGTVRLPGSKSISNRVLLLSALATGETRVRDLLDSDDTRVMLEALKVLGVAWR
REGNDCIVSGVGGNFPSKAADLFMGNAGTAIRPLTAALALQGGTYKLSGVQRMHERPIGDLVDGLRQVGASVDYLGTPGY
PPLQINPAQIRIDAPIRVRGDVSSQFLTALLMTLPMAQAQSGRIEIEVVGELISKPYIEITLNLLSRFGIAVERQGWERF
ILPAGARYRSPGEIYVEGDASTASYFLAAGAIGGGPVRVEGVGMASIQGDVRFADALNRMGANVMAGDNWIEVRGTERDD
GRLNGIELDCNHIPDAAMTLAVAALFAEGTTTLTNIASWRVKETDRISAMATELRKLGAEVEEGADYLKVTPPTSPATWQ
TPDAGIGTYDDHRMAMCFSLAAFGPLPVKINDPGCVAKTFPEYFEVFAGVAR
>Mature_451_residues
PPARAARNGHAAENMEQLTLGPLTRASGTVRLPGSKSISNRVLLLSALATGETRVRDLLDSDDTRVMLEALKVLGVAWRR
EGNDCIVSGVGGNFPSKAADLFMGNAGTAIRPLTAALALQGGTYKLSGVQRMHERPIGDLVDGLRQVGASVDYLGTPGYP
PLQINPAQIRIDAPIRVRGDVSSQFLTALLMTLPMAQAQSGRIEIEVVGELISKPYIEITLNLLSRFGIAVERQGWERFI
LPAGARYRSPGEIYVEGDASTASYFLAAGAIGGGPVRVEGVGMASIQGDVRFADALNRMGANVMAGDNWIEVRGTERDDG
RLNGIELDCNHIPDAAMTLAVAALFAEGTTTLTNIASWRVKETDRISAMATELRKLGAEVEEGADYLKVTPPTSPATWQT
PDAGIGTYDDHRMAMCFSLAAFGPLPVKINDPGCVAKTFPEYFEVFAGVAR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=440, Percent_Identity=55, Blast_Score=447, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6320332, Length=451, Percent_Identity=37.6940133037694, Blast_Score=244, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 48242; Mature: 48110

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPARAARNGHAAENMEQLTLGPLTRASGTVRLPGSKSISNRVLLLSALATGETRVRDLL
CCCCCCCCCCCCHHCHHHHCCCCCCCCCCEEECCCCCCCCCEEEEEEEHHCCHHHHHHHH
DSDDTRVMLEALKVLGVAWRREGNDCIVSGVGGNFPSKAADLFMGNAGTAIRPLTAALAL
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHEECCCCCHHHHHHHHHEE
QGGTYKLSGVQRMHERPIGDLVDGLRQVGASVDYLGTPGYPPLQINPAQIRIDAPIRVRG
CCCCEEEHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCCCCEEECCCEEEECCCEEEEC
DVSSQFLTALLMTLPMAQAQSGRIEIEVVGELISKPYIEITLNLLSRFGIAVERQGWERF
CCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCEEECCCCCEE
ILPAGARYRSPGEIYVEGDASTASYFLAAGAIGGGPVRVEGVGMASIQGDVRFADALNRM
EECCCCCCCCCCEEEEECCCCCHHHHEEECCCCCCCEEEEECEEEECCCCCHHHHHHHHC
GANVMAGDNWIEVRGTERDDGRLNGIELDCNHIPDAAMTLAVAALFAEGTTTLTNIASWR
CCEEEECCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHEE
VKETDRISAMATELRKLGAEVEEGADYLKVTPPTSPATWQTPDAGIGTYDDHRMAMCFSL
ECCHHHHHHHHHHHHHHCCHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AAFGPLPVKINDPGCVAKTFPEYFEVFAGVAR
HHCCCEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PPARAARNGHAAENMEQLTLGPLTRASGTVRLPGSKSISNRVLLLSALATGETRVRDLL
CCCCCCCCCCCHHCHHHHCCCCCCCCCCEEECCCCCCCCCEEEEEEEHHCCHHHHHHHH
DSDDTRVMLEALKVLGVAWRREGNDCIVSGVGGNFPSKAADLFMGNAGTAIRPLTAALAL
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHEECCCCCHHHHHHHHHEE
QGGTYKLSGVQRMHERPIGDLVDGLRQVGASVDYLGTPGYPPLQINPAQIRIDAPIRVRG
CCCCEEEHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCCCCCEEECCCEEEECCCEEEEC
DVSSQFLTALLMTLPMAQAQSGRIEIEVVGELISKPYIEITLNLLSRFGIAVERQGWERF
CCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCEEECCCCCEE
ILPAGARYRSPGEIYVEGDASTASYFLAAGAIGGGPVRVEGVGMASIQGDVRFADALNRM
EECCCCCCCCCCEEEEECCCCCHHHHEEECCCCCCCEEEEECEEEECCCCCHHHHHHHHC
GANVMAGDNWIEVRGTERDDGRLNGIELDCNHIPDAAMTLAVAALFAEGTTTLTNIASWR
CCEEEECCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHEE
VKETDRISAMATELRKLGAEVEEGADYLKVTPPTSPATWQTPDAGIGTYDDHRMAMCFSL
ECCHHHHHHHHHHHHHHCCHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AAFGPLPVKINDPGCVAKTFPEYFEVFAGVAR
HHCCCEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA