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The map label for this gene is clpB [H]

Identifier: 94309563

GI number: 94309563

Start: 677318

End: 679999

Strand: Reverse

Name: clpB [H]

Synonym: Rmet_0618

Alternate gene names: 94309563

Gene position: 679999-677318 (Counterclockwise)

Preceding gene: 94309564

Following gene: 94309562

Centisome position: 17.31

GC content: 64.65

Gene sequence:

>2682_bases
ATGACCACCCGCGATTACTCTCCCTTTCTGCGACGCCTGAACGACCACTGCGCCCGTGCTCTGGCGGATGCAGCCAGTCT
TTGCGAAACCCGCGCGCACCGTGACATCGAGGTGGAGCACTGGCTGATCAAACTGATGGAACAGGGTGACGGCGACCTGC
TTGCCATCCTGCGTCGCTACGAGCTGGATGTCGATGGGATCTGGAACGGACTGCTGGCTGCGGTCGACCACCTGCCGCAT
GACCTCCGGGGCAGGCCGGGGCTATCGCAGCGCCTGGGCCAGTGGCTGGAGGCAGCGTGGATGCGCGCCTCGCTCGAATC
CACGGCCCCGGGCGTAGACAGATCGATTCGTTCGGCCCACTTGCTGGCGGCACTGGCGGAGACGCCGCACCTGTTGCGCG
CCCCGGATGCCTGGCCGCTGCTGAGCGTGTCTGCCGCGCAGATTGAGCGGCTGATGCCTGAACTGGACGAGATATCTGTC
GAGGCAACATCGCCGATCACGCCTAGCCAGGGACCGGCGACCATCGCTACAAGGCGCCCTGCCGGCCAGCCCGACAACTC
TGCCCTCTCTCGTTTCACCACGGACGTCACGCAAAAGGCGCGCGATGGCAAGATCGACCCTGTGTTTGGCCGCGACGTCG
AGATCCGGCAGATGGTCGATATCCTCGCCCGGCGCCGTAAGAACAATCCGATTCTGGTCGGCGAACCGGGGGTCGGCAAA
ACTGCGCTCGTCGAAGGGCTGGCGCTCAAGATCGCCGAAGAGGATGTGCCCACGGCCATCCGGGACGTGACCGTACTCAC
CTTGGATATGGGCCTCCTGCAAGCCGGTGCGGGCGTCAAGGGCGAGTTCGAGCAGCGCCTCAAGAATGTCATTGAAGCCG
TCCAGCAGTCGCCGACGCCCATCCTGCTCTTCATCGACGAGGCGCACACCCTGATTGGCGCCGGCAACACGGCCGGTGGC
GCCGATGCCGCCAACCTGCTCAAGCCTGCACTGGCACGGGGCGAACTACGCACGATCGCGGCAACCACCTGGTCCGAATA
CAAGCAGTACTTCGAGCGCGACGCGGCGCTGGAGCGCCGCTTCCAGATGGTCAAGGTCGATGAGCCCGATGATGAGAACG
CCTGCCTGATGTTGCGCGGGCTCAAGGATCGGTATGCACAGCACCACAACGTCCACATCACCGATGCCGCCGTCGCAGCC
GCCGTCCGTCTTTCACGTCGCTATCTGACTGGGCGCCAACTGCCCGACAAGGCTGTCGACCTGATCGACACGGCGGCTGC
GCGGGTGCGCATGAGTCAGGAGGCCAGGCCCGTGGCGATCTGCACCCTTGAAGCCGAACGCGCGGCGCTGGGGGTCGAGT
ACTTGGCGCTGCAGCAGGATCAGGGTGCCACCGGCGAGGACAAGCGCAATCGTCTGTCGGCGATCGAGACGCGCCTACGC
GAACTTGCCATCGAACTCGGACAGCTTGAGTTCGAATTAGCGGCGCAGAAGGACGCTGCCGACAAGCTGATGGTGCTGCG
TGCCCAATGGCAGGCCGCTACCGACGCTTCCGAGCGCCACGATCTCGCGTCCTCCATTCAGGCTGCCCACCAGGTCCTGG
CCGCGCACGGTCAGGCGACACTTCTACATGCAGAAGTTGCTGAGACCGTCGTGGCGCAGGTAATTGCCGACTGGACCGGC
GTGCCGGTTGACAACCTGTTGTCGAATGAACTGGCCACCCTGCTGGAGCTGGAGGCACGCCTCGGACGGGTCGTGGTCGG
GCAGGACGAGGCGCTGGCCGCGCTCGGCAAAAGCCTGCGCGCCTCCAAGGCGGGCTTGAAATCCGAGGAGGCACCGCTGG
GCGTCTTTCTCCTCGTGGGCCCTTCCGGGGTCGGCAAGACCGAAACGGCACGGGCACTGGCCGATCTCATGTTCGGCGGT
GAACGCTCGCTCATCACGATCAACCTGTCGGAGTATCAGGAAGCCCACACCGTATCGCAATTGAAGGGATCGCCGCCGGG
CTATGTCGGCTATGGCGAGGGCGGCATCCTGACTGAGGCTGTCCGTCAGCGCCCCTACAGCGTGGTCCTCCTGGATGAGG
TGGAAAAGGCCCATCGGGACGTGCTCAACCTGTTCTACCAGGTCTTCGATCGCGGCTTCATGCGCGATGGCGAAGGCCGG
GTCATTGATTTCCGCAACACCGTCATCCTGATGACATCGAATCTCGGCAGCGAGCAAATCCTGGCGGCCACCGACGCCAC
AACGGAAGCTGGTGTGGAAATCCCCGCCAGCGCGCTGATGGAGACCATCCGGCCGCTCCTGATCGACCGCTTCCAACCCG
CGCTGCTGGCGCGCTTCCAGACCATTGTGTACCGGCCGCTCGCCGCGGAGGCCATGGCCACGATCGTAGGGATGAAGCTG
GCCAAGGTGGCCGAGCGCATCGAACGCCGGTTCGACGTGCCGCTGCGCTGCGACGACGCCCTGGTGGCCGAACTGGTGCG
CGCCTGCCTGCTGCCTGACTCTGGCGCACGCAATATCGACAGCCTGCTCGACCAGCAGATCTTGCCCGTGCTGTCGCGTG
AATTGCTGATACGCATGGCCAACAGGCAGGTACCTGCGTCTATCCGGCTCTCGTTCTCCGAGGAGGACGGCATTGGGCTG
GACTTCGATGATGCGGCAACCACCGCGGAGGAATACGCGTGA

Upstream 100 bases:

>100_bases
GAACGAGCGCTCGTAAGCGCCATCGCAGCCGGTGCCTGGCGTCGGCTAGCGAACCAGCGCTCTCGTCTTCTCCACTGCGG
CACCGCAGCGATACGCCACC

Downstream 100 bases:

>100_bases
CGCGCGGCGGGCCGGGTCTCTTCGAAGCCGTCACCGGGTTCTTTGCGAATGGCGTTGCCGTTGACGAGTTAGATGCGTCG
ACCCAGACCTTCCTGTCGGT

Product: Chaperone ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 893; Mature: 892

Protein sequence:

>893_residues
MTTRDYSPFLRRLNDHCARALADAASLCETRAHRDIEVEHWLIKLMEQGDGDLLAILRRYELDVDGIWNGLLAAVDHLPH
DLRGRPGLSQRLGQWLEAAWMRASLESTAPGVDRSIRSAHLLAALAETPHLLRAPDAWPLLSVSAAQIERLMPELDEISV
EATSPITPSQGPATIATRRPAGQPDNSALSRFTTDVTQKARDGKIDPVFGRDVEIRQMVDILARRRKNNPILVGEPGVGK
TALVEGLALKIAEEDVPTAIRDVTVLTLDMGLLQAGAGVKGEFEQRLKNVIEAVQQSPTPILLFIDEAHTLIGAGNTAGG
ADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDENACLMLRGLKDRYAQHHNVHITDAAVAA
AVRLSRRYLTGRQLPDKAVDLIDTAAARVRMSQEARPVAICTLEAERAALGVEYLALQQDQGATGEDKRNRLSAIETRLR
ELAIELGQLEFELAAQKDAADKLMVLRAQWQAATDASERHDLASSIQAAHQVLAAHGQATLLHAEVAETVVAQVIADWTG
VPVDNLLSNELATLLELEARLGRVVVGQDEALAALGKSLRASKAGLKSEEAPLGVFLLVGPSGVGKTETARALADLMFGG
ERSLITINLSEYQEAHTVSQLKGSPPGYVGYGEGGILTEAVRQRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGR
VIDFRNTVILMTSNLGSEQILAATDATTEAGVEIPASALMETIRPLLIDRFQPALLARFQTIVYRPLAAEAMATIVGMKL
AKVAERIERRFDVPLRCDDALVAELVRACLLPDSGARNIDSLLDQQILPVLSRELLIRMANRQVPASIRLSFSEEDGIGL
DFDDAATTAEEYA

Sequences:

>Translated_893_residues
MTTRDYSPFLRRLNDHCARALADAASLCETRAHRDIEVEHWLIKLMEQGDGDLLAILRRYELDVDGIWNGLLAAVDHLPH
DLRGRPGLSQRLGQWLEAAWMRASLESTAPGVDRSIRSAHLLAALAETPHLLRAPDAWPLLSVSAAQIERLMPELDEISV
EATSPITPSQGPATIATRRPAGQPDNSALSRFTTDVTQKARDGKIDPVFGRDVEIRQMVDILARRRKNNPILVGEPGVGK
TALVEGLALKIAEEDVPTAIRDVTVLTLDMGLLQAGAGVKGEFEQRLKNVIEAVQQSPTPILLFIDEAHTLIGAGNTAGG
ADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDENACLMLRGLKDRYAQHHNVHITDAAVAA
AVRLSRRYLTGRQLPDKAVDLIDTAAARVRMSQEARPVAICTLEAERAALGVEYLALQQDQGATGEDKRNRLSAIETRLR
ELAIELGQLEFELAAQKDAADKLMVLRAQWQAATDASERHDLASSIQAAHQVLAAHGQATLLHAEVAETVVAQVIADWTG
VPVDNLLSNELATLLELEARLGRVVVGQDEALAALGKSLRASKAGLKSEEAPLGVFLLVGPSGVGKTETARALADLMFGG
ERSLITINLSEYQEAHTVSQLKGSPPGYVGYGEGGILTEAVRQRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGR
VIDFRNTVILMTSNLGSEQILAATDATTEAGVEIPASALMETIRPLLIDRFQPALLARFQTIVYRPLAAEAMATIVGMKL
AKVAERIERRFDVPLRCDDALVAELVRACLLPDSGARNIDSLLDQQILPVLSRELLIRMANRQVPASIRLSFSEEDGIGL
DFDDAATTAEEYA
>Mature_892_residues
TTRDYSPFLRRLNDHCARALADAASLCETRAHRDIEVEHWLIKLMEQGDGDLLAILRRYELDVDGIWNGLLAAVDHLPHD
LRGRPGLSQRLGQWLEAAWMRASLESTAPGVDRSIRSAHLLAALAETPHLLRAPDAWPLLSVSAAQIERLMPELDEISVE
ATSPITPSQGPATIATRRPAGQPDNSALSRFTTDVTQKARDGKIDPVFGRDVEIRQMVDILARRRKNNPILVGEPGVGKT
ALVEGLALKIAEEDVPTAIRDVTVLTLDMGLLQAGAGVKGEFEQRLKNVIEAVQQSPTPILLFIDEAHTLIGAGNTAGGA
DAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDENACLMLRGLKDRYAQHHNVHITDAAVAAA
VRLSRRYLTGRQLPDKAVDLIDTAAARVRMSQEARPVAICTLEAERAALGVEYLALQQDQGATGEDKRNRLSAIETRLRE
LAIELGQLEFELAAQKDAADKLMVLRAQWQAATDASERHDLASSIQAAHQVLAAHGQATLLHAEVAETVVAQVIADWTGV
PVDNLLSNELATLLELEARLGRVVVGQDEALAALGKSLRASKAGLKSEEAPLGVFLLVGPSGVGKTETARALADLMFGGE
RSLITINLSEYQEAHTVSQLKGSPPGYVGYGEGGILTEAVRQRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRV
IDFRNTVILMTSNLGSEQILAATDATTEAGVEIPASALMETIRPLLIDRFQPALLARFQTIVYRPLAAEAMATIVGMKLA
KVAERIERRFDVPLRCDDALVAELVRACLLPDSGARNIDSLLDQQILPVLSRELLIRMANRQVPASIRLSFSEEDGIGLD
FDDAATTAEEYA

Specific function: Required for secretion of hcp1 probably by providing the energy source for its translocation [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=299, Percent_Identity=34.7826086956522, Blast_Score=171, Evalue=3e-42,
Organism=Escherichia coli, GI1788943, Length=893, Percent_Identity=38.2978723404255, Blast_Score=555, Evalue=1e-159,
Organism=Escherichia coli, GI1787109, Length=277, Percent_Identity=45.8483754512635, Blast_Score=253, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6320464, Length=698, Percent_Identity=40.1146131805158, Blast_Score=478, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6323002, Length=696, Percent_Identity=37.5, Blast_Score=440, Evalue=1e-124,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR017729
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97475; Mature: 97344

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRDYSPFLRRLNDHCARALADAASLCETRAHRDIEVEHWLIKLMEQGDGDLLAILRRY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
ELDVDGIWNGLLAAVDHLPHDLRGRPGLSQRLGQWLEAAWMRASLESTAPGVDRSIRSAH
CCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LLAALAETPHLLRAPDAWPLLSVSAAQIERLMPELDEISVEATSPITPSQGPATIATRRP
HHHHHHHCCCHHCCCCCCCCHHCCHHHHHHHCCHHHHCCCCCCCCCCCCCCCCEEEECCC
AGQPDNSALSRFTTDVTQKARDGKIDPVFGRDVEIRQMVDILARRRKNNPILVGEPGVGK
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCH
TALVEGLALKIAEEDVPTAIRDVTVLTLDMGLLQAGAGVKGEFEQRLKNVIEAVQQSPTP
HHHHHHHHHEECCCCCCHHHHHHHHEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCE
ILLFIDEAHTLIGAGNTAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERR
EEEEEECCCEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FQMVKVDEPDDENACLMLRGLKDRYAQHHNVHITDAAVAAAVRLSRRYLTGRQLPDKAVD
HHEEECCCCCCCCCEEEEECHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHH
LIDTAAARVRMSQEARPVAICTLEAERAALGVEYLALQQDQGATGEDKRNRLSAIETRLR
HHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHH
ELAIELGQLEFELAAQKDAADKLMVLRAQWQAATDASERHDLASSIQAAHQVLAAHGQAT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHH
LLHAEVAETVVAQVIADWTGVPVDNLLSNELATLLELEARLGRVVVGQDEALAALGKSLR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHH
ASKAGLKSEEAPLGVFLLVGPSGVGKTETARALADLMFGGERSLITINLSEYQEAHTVSQ
HHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
LKGSPPGYVGYGEGGILTEAVRQRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGR
HCCCCCCEEECCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VIDFRNTVILMTSNLGSEQILAATDATTEAGVEIPASALMETIRPLLIDRFQPALLARFQ
EEEECCEEEEEECCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
TIVYRPLAAEAMATIVGMKLAKVAERIERRFDVPLRCDDALVAELVRACLLPDSGARNID
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
SLLDQQILPVLSRELLIRMANRQVPASIRLSFSEEDGIGLDFDDAATTAEEYA
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TTRDYSPFLRRLNDHCARALADAASLCETRAHRDIEVEHWLIKLMEQGDGDLLAILRRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
ELDVDGIWNGLLAAVDHLPHDLRGRPGLSQRLGQWLEAAWMRASLESTAPGVDRSIRSAH
CCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LLAALAETPHLLRAPDAWPLLSVSAAQIERLMPELDEISVEATSPITPSQGPATIATRRP
HHHHHHHCCCHHCCCCCCCCHHCCHHHHHHHCCHHHHCCCCCCCCCCCCCCCCEEEECCC
AGQPDNSALSRFTTDVTQKARDGKIDPVFGRDVEIRQMVDILARRRKNNPILVGEPGVGK
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCH
TALVEGLALKIAEEDVPTAIRDVTVLTLDMGLLQAGAGVKGEFEQRLKNVIEAVQQSPTP
HHHHHHHHHEECCCCCCHHHHHHHHEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCE
ILLFIDEAHTLIGAGNTAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERR
EEEEEECCCEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FQMVKVDEPDDENACLMLRGLKDRYAQHHNVHITDAAVAAAVRLSRRYLTGRQLPDKAVD
HHEEECCCCCCCCCEEEEECHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHH
LIDTAAARVRMSQEARPVAICTLEAERAALGVEYLALQQDQGATGEDKRNRLSAIETRLR
HHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHH
ELAIELGQLEFELAAQKDAADKLMVLRAQWQAATDASERHDLASSIQAAHQVLAAHGQAT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHH
LLHAEVAETVVAQVIADWTGVPVDNLLSNELATLLELEARLGRVVVGQDEALAALGKSLR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHH
ASKAGLKSEEAPLGVFLLVGPSGVGKTETARALADLMFGGERSLITINLSEYQEAHTVSQ
HHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHH
LKGSPPGYVGYGEGGILTEAVRQRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGR
HCCCCCCEEECCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VIDFRNTVILMTSNLGSEQILAATDATTEAGVEIPASALMETIRPLLIDRFQPALLARFQ
EEEECCEEEEEECCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
TIVYRPLAAEAMATIVGMKLAKVAERIERRFDVPLRCDDALVAELVRACLLPDSGARNID
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
SLLDQQILPVLSRELLIRMANRQVPASIRLSFSEEDGIGLDFDDAATTAEEYA
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]