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The map label for this gene is citT [C]

Identifier: 94309505

GI number: 94309505

Start: 598936

End: 600459

Strand: Reverse

Name: citT [C]

Synonym: Rmet_0560

Alternate gene names: 94309505

Gene position: 600459-598936 (Counterclockwise)

Preceding gene: 94309507

Following gene: 94309504

Centisome position: 15.29

GC content: 64.76

Gene sequence:

>1524_bases
ATGCCTGAATCACAAGTACCTCCTGCCGCCTCCGGCGCCCCCACCGCCGCGACGGCCGTCGCGGCCGCGCCCAAGCTCAA
TATCCACTGGGGTCTGTATGCGGCCGTGGTCGTGCTGATCGCGGTGCTCCTGATACCGATGCCGGCTGACCTGCCTGTGG
CCGGTCAGCGCATGCTGGCCATCCTGGCATTCGCGGTCGTGGTGTGGATTACCGAAGCGGTGACCTACGAGACCAGCGCC
ATCATGATCACGTCGCTGATGGCCGGCCTGATCGGCTTCGCGCCGATGGTCAATGACCCCAACACGCTATATGGCACATC
GCGCGCGCTTGGCATGGCCCTGGCGGGCTTCTCGAACACCGCGCTGGCCCTCGTCGCCGCCGCGCTGTTCATCTCGGCGG
CCATGACCGTGACCGGACTGGACCGGCGCATCGCGCTGGTCACCTTGTCGGCCATCGGCACCAGTACCCGACGCATCCTG
ATCGGCACGATCGCCGTCACGATCCTGCTCAGCCTGGTGGTGCCGAGCGCCACCGCGCGCAGCGCATGTACCGTGCCGAT
CATGATGGGCGTGATCGCCGCATTCGGCGTCGACAAGAAGTCGAACATCGCAGCCGGCATCATGATCATGGTCGCGCAAG
CCACCAGCGTCTGGAACGTCGGTATCCAGACCGCCGCCGCACAGAACCTGCTGACCGCGGGCTTCATGGACAAGCTGCTC
GGCGAACGCGTGACCTGGCTGCAATGGCTGATTGCCGGCGCTCCCTGGGCCATCGTGATGTCGATCGTGCTGTACTTCCT
CGTGCGCTGGCTGCTTCCGCCTGAAACCGACGCAATTGCGGGCGGCAAGGAAGCCGTGCAGCGTGAGCTGGCCGCGCTGG
GTCCGATGACGGGCCCGCAGAAGCGCCTGGCTGCCGTCGCCATCGGCCTGCTGCTGTTCTGGGCCACCGAGGGCAAGCTG
CACAAGTTCGATACGGCGTCGATCACGTTCGTGGGCCTGGTGATCCTGATGCTGCCGCGCATCGGCGTGATGGACTGGAA
GACGATGCAGCAACGCACGCCATGGGGCACGCTGATCGTGTTCGGCGTTGGTATCAGCCTGGGCACCGCGCTGCTGACCA
CGCAGGCCGGCCAATGGCTCGGGAAATTCGTCGTCACGCATTCCGGCCTGGCCAATCACGGCACGCTGCTGGTCTTTGCC
GTGCTGGCGGCATTCCTGATCCTGATCCACCTCGGCTTTGCCAGCGCCACGGCACTGACCTCCGCGATGCTGCCGATCCT
GATCTCGGTACTGCAAACCATACCCGGTGACATGAACAAGGTCGGCATGACGATGCTGCTCGGCTTCACGGTCAGCTTCG
GCTTCATCCTGCCCATCAACGCACCGCAGAACATGGTCTGCCTCGGCACCGATACCTTCAACGGGCGACAGTTCGCGCGC
ATCGGCATCCCGACCACGATCATCGGGTATCTGCTGATGCTGCTGTTCGCGTCGACGTACTGGCGCTGGCTTGGCTGGAT
CTGA

Upstream 100 bases:

>100_bases
TGGCACATCGGCCTTGGCTTCACATAATGAGCCCATGTCGGCCGCGGCGATCCTGCGATACGACGCGACTGGCAGGCTGA
TCCAACATAGGGATTCCACG

Downstream 100 bases:

>100_bases
CCGGCAAACATGCAACCTCGCCGCTGACACAAGCGCCCCCAAACCTTCGCCCCCAACGATGATGAAAATTACCCTAGACA
GCGCGCGGCAGTTCGCGCGC

Product: Sodium:sulfate symporter transmembrane region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MPESQVPPAASGAPTAATAVAAAPKLNIHWGLYAAVVVLIAVLLIPMPADLPVAGQRMLAILAFAVVVWITEAVTYETSA
IMITSLMAGLIGFAPMVNDPNTLYGTSRALGMALAGFSNTALALVAAALFISAAMTVTGLDRRIALVTLSAIGTSTRRIL
IGTIAVTILLSLVVPSATARSACTVPIMMGVIAAFGVDKKSNIAAGIMIMVAQATSVWNVGIQTAAAQNLLTAGFMDKLL
GERVTWLQWLIAGAPWAIVMSIVLYFLVRWLLPPETDAIAGGKEAVQRELAALGPMTGPQKRLAAVAIGLLLFWATEGKL
HKFDTASITFVGLVILMLPRIGVMDWKTMQQRTPWGTLIVFGVGISLGTALLTTQAGQWLGKFVVTHSGLANHGTLLVFA
VLAAFLILIHLGFASATALTSAMLPILISVLQTIPGDMNKVGMTMLLGFTVSFGFILPINAPQNMVCLGTDTFNGRQFAR
IGIPTTIIGYLLMLLFASTYWRWLGWI

Sequences:

>Translated_507_residues
MPESQVPPAASGAPTAATAVAAAPKLNIHWGLYAAVVVLIAVLLIPMPADLPVAGQRMLAILAFAVVVWITEAVTYETSA
IMITSLMAGLIGFAPMVNDPNTLYGTSRALGMALAGFSNTALALVAAALFISAAMTVTGLDRRIALVTLSAIGTSTRRIL
IGTIAVTILLSLVVPSATARSACTVPIMMGVIAAFGVDKKSNIAAGIMIMVAQATSVWNVGIQTAAAQNLLTAGFMDKLL
GERVTWLQWLIAGAPWAIVMSIVLYFLVRWLLPPETDAIAGGKEAVQRELAALGPMTGPQKRLAAVAIGLLLFWATEGKL
HKFDTASITFVGLVILMLPRIGVMDWKTMQQRTPWGTLIVFGVGISLGTALLTTQAGQWLGKFVVTHSGLANHGTLLVFA
VLAAFLILIHLGFASATALTSAMLPILISVLQTIPGDMNKVGMTMLLGFTVSFGFILPINAPQNMVCLGTDTFNGRQFAR
IGIPTTIIGYLLMLLFASTYWRWLGWI
>Mature_506_residues
PESQVPPAASGAPTAATAVAAAPKLNIHWGLYAAVVVLIAVLLIPMPADLPVAGQRMLAILAFAVVVWITEAVTYETSAI
MITSLMAGLIGFAPMVNDPNTLYGTSRALGMALAGFSNTALALVAAALFISAAMTVTGLDRRIALVTLSAIGTSTRRILI
GTIAVTILLSLVVPSATARSACTVPIMMGVIAAFGVDKKSNIAAGIMIMVAQATSVWNVGIQTAAAQNLLTAGFMDKLLG
ERVTWLQWLIAGAPWAIVMSIVLYFLVRWLLPPETDAIAGGKEAVQRELAALGPMTGPQKRLAAVAIGLLLFWATEGKLH
KFDTASITFVGLVILMLPRIGVMDWKTMQQRTPWGTLIVFGVGISLGTALLTTQAGQWLGKFVVTHSGLANHGTLLVFAV
LAAFLILIHLGFASATALTSAMLPILISVLQTIPGDMNKVGMTMLLGFTVSFGFILPINAPQNMVCLGTDTFNGRQFARI
GIPTTIIGYLLMLLFASTYWRWLGWI

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. SODIT1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786829, Length=486, Percent_Identity=27.5720164609054, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789444, Length=490, Percent_Identity=25.9183673469388, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786986, Length=321, Percent_Identity=29.2834890965732, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71988385, Length=419, Percent_Identity=23.3890214797136, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32565804, Length=419, Percent_Identity=23.3890214797136, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71989118, Length=458, Percent_Identity=20.7423580786026, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI281366409, Length=547, Percent_Identity=22.3034734917733, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737623, Length=547, Percent_Identity=22.3034734917733, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666468, Length=547, Percent_Identity=22.3034734917733, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551633, Length=547, Percent_Identity=22.3034734917733, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 53526; Mature: 53395

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESQVPPAASGAPTAATAVAAAPKLNIHWGLYAAVVVLIAVLLIPMPADLPVAGQRMLA
CCCCCCCCCCCCCCCHHHHHHHCCCCEECHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ILAFAVVVWITEAVTYETSAIMITSLMAGLIGFAPMVNDPNTLYGTSRALGMALAGFSNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHH
ALALVAAALFISAAMTVTGLDRRIALVTLSAIGTSTRRILIGTIAVTILLSLVVPSATAR
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SACTVPIMMGVIAAFGVDKKSNIAAGIMIMVAQATSVWNVGIQTAAAQNLLTAGFMDKLL
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GERVTWLQWLIAGAPWAIVMSIVLYFLVRWLLPPETDAIAGGKEAVQRELAALGPMTGPQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHH
KRLAAVAIGLLLFWATEGKLHKFDTASITFVGLVILMLPRIGVMDWKTMQQRTPWGTLIV
HHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEE
FGVGISLGTALLTTQAGQWLGKFVVTHSGLANHGTLLVFAVLAAFLILIHLGFASATALT
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAMLPILISVLQTIPGDMNKVGMTMLLGFTVSFGFILPINAPQNMVCLGTDTFNGRQFAR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCEEEE
IGIPTTIIGYLLMLLFASTYWRWLGWI
CCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PESQVPPAASGAPTAATAVAAAPKLNIHWGLYAAVVVLIAVLLIPMPADLPVAGQRMLA
CCCCCCCCCCCCCCHHHHHHHCCCCEECHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ILAFAVVVWITEAVTYETSAIMITSLMAGLIGFAPMVNDPNTLYGTSRALGMALAGFSNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHH
ALALVAAALFISAAMTVTGLDRRIALVTLSAIGTSTRRILIGTIAVTILLSLVVPSATAR
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SACTVPIMMGVIAAFGVDKKSNIAAGIMIMVAQATSVWNVGIQTAAAQNLLTAGFMDKLL
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GERVTWLQWLIAGAPWAIVMSIVLYFLVRWLLPPETDAIAGGKEAVQRELAALGPMTGPQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHH
KRLAAVAIGLLLFWATEGKLHKFDTASITFVGLVILMLPRIGVMDWKTMQQRTPWGTLIV
HHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEE
FGVGISLGTALLTTQAGQWLGKFVVTHSGLANHGTLLVFAVLAAFLILIHLGFASATALT
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAMLPILISVLQTIPGDMNKVGMTMLLGFTVSFGFILPINAPQNMVCLGTDTFNGRQFAR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCEEEE
IGIPTTIIGYLLMLLFASTYWRWLGWI
CCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8405966 [H]