BacMap

Definition	Cupriavidus metallidurans CH34 chromosome, complete genome.
Accession	NC_007973
Length	3,928,089

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The map label for this gene is bdhA [H]

Identifier: 94309491

GI number: 94309491

Start: 581554

End: 582330

Strand: Reverse

Name: bdhA [H]

Synonym: Rmet_0546

Alternate gene names: 94309491

Gene position: 582330-581554 (Counterclockwise)

Preceding gene: 94309492

Following gene: 94309487

Centisome position: 14.82

GC content: 65.51

Gene sequence:

>777_bases
ATGGTCAATCTGCAAGGCAAGACCGCGCTGGTCACCGGCTCCACCAGCGGCATCGGACTGGGTATCGCCGAAGCGTTGGG
CCGCGCTGGCGCGAACATCGTGCTGAACGGCTTCGGCGATGTCGACGCGGCGCTCGCCACAATCGCGGCAACTGGCGCGC
AATCGGCCCATCACCCGGCGGACATGCGCAAGCCCGATGAGATCGAAGCGATGATCGCCATGGCACGGGAACGCTTTGGC
ACCGTGGACGTGCTGGTCAACAACGCTGGTATCCAGCATGTGGCGCAGGTGGAGGACTTTCCCGCGCAGAAGTGGGACGA
CATCCTGGCCATCAACCTGACGTCGAGCTTCCACACGACGCGGCACGTGATTCCCGCGATGCGGGCCCGTAACTGGGGTC
GTATCGTCAATATCGCGTCGGTGCACGGGCTTGTCGGCTCGGCCGGCAAGTCCGCCTACGTGGCAGCCAAGCATGGTCTC
GTCGGGCTGACCAAGGTCACCGCGCTGGAAACGGCCGGTACCGGCATCACCTGCAACGCGATCTGTCCCGGCTTCGTGCT
GACGCCGCTGGTAGCGGCGCAAATCGATGCGATCGCGAAGCGAGACGGTATTTCGATGGAAGCGGCCCGGGCACGGCTGC
TGTCGGACAAGCAGCCCTCGGGGCAGTTCGTCACGCCGGAGCAGTTGGGCAATCTGGTGCTGATGCTCTGTTCGCCGTTC
GGCGATCAGGTGCGCGGCGCGGCCTGGGCCATGGACGGCGGCTGGACCGCGCAATAG

Upstream 100 bases:

>100_bases
GTCGTATCGCGACATCTTCGCGATCACGATGATCAAGACGATGGCGGTGTTCTTCGTCATCTTCGTGTTCTACGCCACCG
GTCTGGTCTAAGGAGCGGCA

Downstream 100 bases:

>100_bases
CTGTAGCAGTCGCGACACCGCGCGCCACGCCGCATCCGGCATGGCGCGCGGCAGATTGGCGGCGTCTTACAACCCGCCTA
CCCCAGGGAATGTGATCACG

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MVNLQGKTALVTGSTSGIGLGIAEALGRAGANIVLNGFGDVDAALATIAATGAQSAHHPADMRKPDEIEAMIAMARERFG
TVDVLVNNAGIQHVAQVEDFPAQKWDDILAINLTSSFHTTRHVIPAMRARNWGRIVNIASVHGLVGSAGKSAYVAAKHGL
VGLTKVTALETAGTGITCNAICPGFVLTPLVAAQIDAIAKRDGISMEAARARLLSDKQPSGQFVTPEQLGNLVLMLCSPF
GDQVRGAAWAMDGGWTAQ

Sequences:

>Translated_258_residues
MVNLQGKTALVTGSTSGIGLGIAEALGRAGANIVLNGFGDVDAALATIAATGAQSAHHPADMRKPDEIEAMIAMARERFG
TVDVLVNNAGIQHVAQVEDFPAQKWDDILAINLTSSFHTTRHVIPAMRARNWGRIVNIASVHGLVGSAGKSAYVAAKHGL
VGLTKVTALETAGTGITCNAICPGFVLTPLVAAQIDAIAKRDGISMEAARARLLSDKQPSGQFVTPEQLGNLVLMLCSPF
GDQVRGAAWAMDGGWTAQ
>Mature_258_residues
MVNLQGKTALVTGSTSGIGLGIAEALGRAGANIVLNGFGDVDAALATIAATGAQSAHHPADMRKPDEIEAMIAMARERFG
TVDVLVNNAGIQHVAQVEDFPAQKWDDILAINLTSSFHTTRHVIPAMRARNWGRIVNIASVHGLVGSAGKSAYVAAKHGL
VGLTKVTALETAGTGITCNAICPGFVLTPLVAAQIDAIAKRDGISMEAARARLLSDKQPSGQFVTPEQLGNLVLMLCSPF
GDQVRGAAWAMDGGWTAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=31.7647058823529, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI4504505, Length=270, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=31.7829457364341, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI31542939, Length=213, Percent_Identity=32.3943661971831, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=34.0425531914894, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI5031737, Length=188, Percent_Identity=34.0425531914894, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=33.1491712707182, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=27.5862068965517, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4758504, Length=207, Percent_Identity=32.3671497584541, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI59889578, Length=132, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI40254992, Length=255, Percent_Identity=28.2352941176471, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI20149619, Length=209, Percent_Identity=30.1435406698565, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4503817, Length=194, Percent_Identity=30.4123711340206, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI83715985, Length=190, Percent_Identity=31.5789473684211, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=32, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI40807363, Length=192, Percent_Identity=27.6041666666667, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40254986, Length=242, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=28.957528957529, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI142976729, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI7706318, Length=188, Percent_Identity=28.1914893617021, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=26.4591439688716, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI310128830, Length=199, Percent_Identity=27.6381909547739, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI310115468, Length=199, Percent_Identity=27.6381909547739, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=27.6515151515151, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI109715829, Length=242, Percent_Identity=26.8595041322314, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI25282469, Length=213, Percent_Identity=26.7605633802817, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI209862901, Length=231, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI19923983, Length=231, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI4503301, Length=257, Percent_Identity=24.5136186770428, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI225579078, Length=211, Percent_Identity=28.9099526066351, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=35.2713178294574, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=34.7826086956522, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=32.6848249027237, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=33.984375, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=31.640625, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=30.4347826086957, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI2367175, Length=238, Percent_Identity=31.5126050420168, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789057, Length=191, Percent_Identity=33.5078534031414, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=28.1853281853282, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=29.296875, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367365, Length=255, Percent_Identity=30.9803921568627, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=30.0546448087432, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1786701, Length=204, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789378, Length=193, Percent_Identity=25.3886010362694, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=29.6875, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=29.5019157088123, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI193203115, Length=204, Percent_Identity=32.3529411764706, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193203117, Length=206, Percent_Identity=32.0388349514563, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17564282, Length=194, Percent_Identity=30.9278350515464, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=29.2307692307692, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=194, Percent_Identity=32.4742268041237, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17538182, Length=201, Percent_Identity=32.3383084577114, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=212, Percent_Identity=30.188679245283, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=27.4509803921569, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=189, Percent_Identity=29.1005291005291, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=279, Percent_Identity=27.2401433691756, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=25.187969924812, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=196, Percent_Identity=29.0816326530612, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555612, Length=210, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=30.03663003663, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=244, Percent_Identity=26.6393442622951, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=196, Percent_Identity=27.5510204081633, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=195, Percent_Identity=24.6153846153846, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=25.830258302583, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=204, Percent_Identity=28.921568627451, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=264, Percent_Identity=26.5151515151515, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=202, Percent_Identity=29.2079207920792, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=26.1992619926199, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=24.812030075188, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71997099, Length=211, Percent_Identity=28.436018957346, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=23.6842105263158, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=246, Percent_Identity=25.609756097561, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=280, Percent_Identity=25.7142857142857, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=200, Percent_Identity=32.5, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=191, Percent_Identity=25.6544502617801, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=30.078125, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355319, Length=261, Percent_Identity=29.8850574712644, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=31.3725490196078, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24644339, Length=193, Percent_Identity=32.6424870466321, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859837, Length=193, Percent_Identity=32.1243523316062, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357041, Length=212, Percent_Identity=30.188679245283, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=29.6577946768061, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21355631, Length=168, Percent_Identity=31.547619047619, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=26.8041237113402, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI17737361, Length=204, Percent_Identity=30.3921568627451, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24643142, Length=274, Percent_Identity=26.6423357664234, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357673, Length=252, Percent_Identity=25.7936507936508, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221510726, Length=188, Percent_Identity=28.1914893617021, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571387, Length=209, Percent_Identity=27.7511961722488, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644337, Length=261, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=33.6842105263158, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581726, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584744, Length=203, Percent_Identity=29.064039408867, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574402, Length=201, Percent_Identity=28.8557213930348, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364892, Length=166, Percent_Identity=25.9036144578313, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356301, Length=196, Percent_Identity=25, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331218, Length=196, Percent_Identity=29.5918367346939, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24665243, Length=196, Percent_Identity=29.5918367346939, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 26786; Mature: 26786

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLQGKTALVTGSTSGIGLGIAEALGRAGANIVLNGFGDVDAALATIAATGAQSAHHPA
CCCCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCC
DMRKPDEIEAMIAMARERFGTVDVLVNNAGIQHVAQVEDFPAQKWDDILAINLTSSFHTT
CCCCCHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCCCCCCEEEEEECCCHHHH
RHVIPAMRARNWGRIVNIASVHGLVGSAGKSAYVAAKHGLVGLTKVTALETAGTGITCNA
HHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCEEEEECCCCEEHHHHEEEECCCCCEEECC
ICPGFVLTPLVAAQIDAIAKRDGISMEAARARLLSDKQPSGQFVTPEQLGNLVLMLCSPF
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEECHHHHHHEEEEEECCC
GDQVRGAAWAMDGGWTAQ
CCHHCCEEEEECCCCCCC
>Mature Secondary Structure
MVNLQGKTALVTGSTSGIGLGIAEALGRAGANIVLNGFGDVDAALATIAATGAQSAHHPA
CCCCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCC
DMRKPDEIEAMIAMARERFGTVDVLVNNAGIQHVAQVEDFPAQKWDDILAINLTSSFHTT
CCCCCHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCCCCCCEEEEEECCCHHHH
RHVIPAMRARNWGRIVNIASVHGLVGSAGKSAYVAAKHGLVGLTKVTALETAGTGITCNA
HHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCEEEEECCCCEEHHHHEEEECCCCCEEECC
ICPGFVLTPLVAAQIDAIAKRDGISMEAARARLLSDKQPSGQFVTPEQLGNLVLMLCSPF
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEECHHHHHHEEEEEECCC
GDQVRGAAWAMDGGWTAQ
CCHHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA