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The map label for this gene is xseA [H]

Identifier: 94309483

GI number: 94309483

Start: 572770

End: 574215

Strand: Direct

Name: xseA [H]

Synonym: Rmet_0538

Alternate gene names: 94309483

Gene position: 572770-574215 (Clockwise)

Preceding gene: 335055497

Following gene: 335055498

Centisome position: 14.58

GC content: 66.32

Gene sequence:

>1446_bases
TTGACATTGCCGGTATGCTGTGGACATGTCCATCCCAGGCCGCGTGCGCGGCTGCGAACCATGCCAGACAACGAGAACTT
TCCGCGCGCGATGCCGTCTCAGCCGCCCACGCGCACCCGTGATGTGATCCAGGTCAGTGAACTGAATCACGCCATCGCCG
GCGTGCTCGAACGCAGCTTTCCACTCGCCTGGGTCCGGGGAGAGATCTCGAATTTCACGCGGGCGGCCAGTGGGCATTGG
TATTTCTCGCTCAAGGACGCACGCGCGCAGATTCGTTGTGTGATGTTTCGCGGGCGTAATCAGCATGTCGACTTTTCGCC
ACGCGAAGGGGAGGCTGTCGAGGTGCGCGCGCTGGTGTCGATGTATGAGGCGCGTGGTGAACTGCAACTCGGCGTCGAAG
CCATGCGTCGTGCCGGGCTCGGGAATCTCTACGAGGCGTTCTTGCGGCTCAAGGAAAAACTGGCGCAGGCAGGTCTGTTC
GATACTGAGCGGAAACGCCCCATTCCGGATCATCCGCGTGTGATCGGCGTGGTGACCTCGCTGCAGGCCGCTGCGATGCG
CGACGTGTTGACCACGTTGCAACGCCGCGCCCCGCATGTGCCGGTGATCGTCTATCCGGTGCCAGTCCAGGGGGCGGGCG
CTGCGGAAAAAATCGCCGCGATGCTCGACACCGCCAGCGCGAGGCGCGAATGCGACGTGCTGATCCTCTGCCGGGGCGGC
GGCAGCATCGAAGACCTCTGGTCGTTCAATGAGGAAGTGGTGGCGCATGCCATCGCGCGGTGTGCCGTGCCCGTGGTCTC
CGGTGTCGGTCACGAAACCGATTTCACGATTGCCGATTTCGTGGCCGACGTGCGCGCGCCGACGCCAACCGGCGCGGCGG
AACTGGTGAGCCCCGACCGCGCGCATCTGCTTCAGGCCACGCGCCGTGCCCGTGATGCGCTGGCGCAGGCAATGGACCGG
CAACTCGAGCGTCGCGCGCAGCATCTGGAATGGCTCGGACGCAGGTTGCGCAGCCCGCAGGCGCAGTTGCAGGAGCGTCG
CGCCCAGGTCGACAATCTGGCCCGGCACATGCGCTCGGCACTGCGCGATACGGTGGCCGTACAGCGCCACCGCGTGGACG
TGCTGGCAATGCGCTGGCGTGCCTGCAAGCCCGACATTGGTGCGGCGCAGGCGGAGCTGGGCCGCCTGGCGGCACGCATG
GCAGCTGCGGCCGCACGGCGGCATGAGCGCGAGACGGCACGCTTGGCGCGTGCGTCGGGCGCGCTGGAACTGCTGGCGCC
CCAACGAACGCTTGAGCGTGGCTATGCGGTGTTGCTTGACAATCGTGGCCGCGCCCTGCGGTCGCCGGTCGAGTTGCGTG
CAGGCAGCATTGTCGAAGCACATCTGGCGGACGGGGTTGCCGACATCGAAATCGCCGGTGTGCAGGCCAAGCTGGCGAGC
TTCTGA

Upstream 100 bases:

>100_bases
ATTGCCTGTTTTTTGCGCCGTCCAAAAAATCATAAGAATCAAAGGCTTGCACCAGAACATGCGGATTGCGGCCAGGCGCG
CGTGAAGGGGGAGGTGCCCC

Downstream 100 bases:

>100_bases
CAACCTCCCCCGGCCCTGTGCCGGGGAAACTAACATGAGGGCAGGGGGCTTTCCGACGTCGTTTGCGCGGGTCTGGCAAG
TCACCTACAATCGGCAGTTC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTLPVCCGHVHPRPRARLRTMPDNENFPRAMPSQPPTRTRDVIQVSELNHAIAGVLERSFPLAWVRGEISNFTRAASGHW
YFSLKDARAQIRCVMFRGRNQHVDFSPREGEAVEVRALVSMYEARGELQLGVEAMRRAGLGNLYEAFLRLKEKLAQAGLF
DTERKRPIPDHPRVIGVVTSLQAAAMRDVLTTLQRRAPHVPVIVYPVPVQGAGAAEKIAAMLDTASARRECDVLILCRGG
GSIEDLWSFNEEVVAHAIARCAVPVVSGVGHETDFTIADFVADVRAPTPTGAAELVSPDRAHLLQATRRARDALAQAMDR
QLERRAQHLEWLGRRLRSPQAQLQERRAQVDNLARHMRSALRDTVAVQRHRVDVLAMRWRACKPDIGAAQAELGRLAARM
AAAAARRHERETARLARASGALELLAPQRTLERGYAVLLDNRGRALRSPVELRAGSIVEAHLADGVADIEIAGVQAKLAS
F

Sequences:

>Translated_481_residues
MTLPVCCGHVHPRPRARLRTMPDNENFPRAMPSQPPTRTRDVIQVSELNHAIAGVLERSFPLAWVRGEISNFTRAASGHW
YFSLKDARAQIRCVMFRGRNQHVDFSPREGEAVEVRALVSMYEARGELQLGVEAMRRAGLGNLYEAFLRLKEKLAQAGLF
DTERKRPIPDHPRVIGVVTSLQAAAMRDVLTTLQRRAPHVPVIVYPVPVQGAGAAEKIAAMLDTASARRECDVLILCRGG
GSIEDLWSFNEEVVAHAIARCAVPVVSGVGHETDFTIADFVADVRAPTPTGAAELVSPDRAHLLQATRRARDALAQAMDR
QLERRAQHLEWLGRRLRSPQAQLQERRAQVDNLARHMRSALRDTVAVQRHRVDVLAMRWRACKPDIGAAQAELGRLAARM
AAAAARRHERETARLARASGALELLAPQRTLERGYAVLLDNRGRALRSPVELRAGSIVEAHLADGVADIEIAGVQAKLAS
F
>Mature_480_residues
TLPVCCGHVHPRPRARLRTMPDNENFPRAMPSQPPTRTRDVIQVSELNHAIAGVLERSFPLAWVRGEISNFTRAASGHWY
FSLKDARAQIRCVMFRGRNQHVDFSPREGEAVEVRALVSMYEARGELQLGVEAMRRAGLGNLYEAFLRLKEKLAQAGLFD
TERKRPIPDHPRVIGVVTSLQAAAMRDVLTTLQRRAPHVPVIVYPVPVQGAGAAEKIAAMLDTASARRECDVLILCRGGG
SIEDLWSFNEEVVAHAIARCAVPVVSGVGHETDFTIADFVADVRAPTPTGAAELVSPDRAHLLQATRRARDALAQAMDRQ
LERRAQHLEWLGRRLRSPQAQLQERRAQVDNLARHMRSALRDTVAVQRHRVDVLAMRWRACKPDIGAAQAELGRLAARMA
AAAARRHERETARLARASGALELLAPQRTLERGYAVLLDNRGRALRSPVELRAGSIVEAHLADGVADIEIAGVQAKLASF

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=449, Percent_Identity=41.8708240534521, Blast_Score=345, Evalue=4e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 53158; Mature: 53027

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPVCCGHVHPRPRARLRTMPDNENFPRAMPSQPPTRTRDVIQVSELNHAIAGVLERSF
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PLAWVRGEISNFTRAASGHWYFSLKDARAQIRCVMFRGRNQHVDFSPREGEAVEVRALVS
CHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
MYEARGELQLGVEAMRRAGLGNLYEAFLRLKEKLAQAGLFDTERKRPIPDHPRVIGVVTS
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
LQAAAMRDVLTTLQRRAPHVPVIVYPVPVQGAGAAEKIAAMLDTASARRECDVLILCRGG
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCC
GSIEDLWSFNEEVVAHAIARCAVPVVSGVGHETDFTIADFVADVRAPTPTGAAELVSPDR
CCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCHH
AHLLQATRRARDALAQAMDRQLERRAQHLEWLGRRLRSPQAQLQERRAQVDNLARHMRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LRDTVAVQRHRVDVLAMRWRACKPDIGAAQAELGRLAARMAAAAARRHERETARLARASG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ALELLAPQRTLERGYAVLLDNRGRALRSPVELRAGSIVEAHLADGVADIEIAGVQAKLAS
CHHHHCCHHHHHCCCEEEEECCCCHHCCCHHHCCCCEEHHHHHCCCCCEEEECHHHHHHC
F
C
>Mature Secondary Structure 
TLPVCCGHVHPRPRARLRTMPDNENFPRAMPSQPPTRTRDVIQVSELNHAIAGVLERSF
CCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PLAWVRGEISNFTRAASGHWYFSLKDARAQIRCVMFRGRNQHVDFSPREGEAVEVRALVS
CHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
MYEARGELQLGVEAMRRAGLGNLYEAFLRLKEKLAQAGLFDTERKRPIPDHPRVIGVVTS
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
LQAAAMRDVLTTLQRRAPHVPVIVYPVPVQGAGAAEKIAAMLDTASARRECDVLILCRGG
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCC
GSIEDLWSFNEEVVAHAIARCAVPVVSGVGHETDFTIADFVADVRAPTPTGAAELVSPDR
CCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCHH
AHLLQATRRARDALAQAMDRQLERRAQHLEWLGRRLRSPQAQLQERRAQVDNLARHMRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LRDTVAVQRHRVDVLAMRWRACKPDIGAAQAELGRLAARMAAAAARRHERETARLARASG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ALELLAPQRTLERGYAVLLDNRGRALRSPVELRAGSIVEAHLADGVADIEIAGVQAKLAS
CHHHHCCHHHHHCCCEEEEECCCCHHCCCHHHCCCCEEHHHHHCCCCCEEEECHHHHHHC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA