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The map label for this gene is xerD [H]

Identifier: 94309464

GI number: 94309464

Start: 555094

End: 556002

Strand: Reverse

Name: xerD [H]

Synonym: Rmet_0519

Alternate gene names: 94309464

Gene position: 556002-555094 (Counterclockwise)

Preceding gene: 94309465

Following gene: 94309463

Centisome position: 14.15

GC content: 67.66

Gene sequence:

>909_bases
ATGACGGCGGCACTCGATGGCGACCTGTCGCTGGTCGACCGGTTCTGCGATGCGTTGTGGCTCGAAGATGGCCTGGCACG
CAATACGATCGACGCCTACCGGCGCGACCTGGCCATGCTGGCGCGCTGGCTGCACGAGTCCGGCACCACGGCGTTACTGG
GCGTCGACGACACCGCGCTTTCCGGATACTTCGCCGCGCGTCACCTGGAGACGCGCGCTTCCTCGGCCAATCGCCGCCTG
ACTGTGTTCCGCCGTTTCTATCAGTGGGCCCTGCGCGAGCACATGATCGAGGCCGACCCCTGCCTGCTGCTGCGCCCCGC
CAAGCAGCCACCCCGGTTCCCGAAGACGCTGTCCGAGGCACAGGTGGTGGCGCTGCTGGAAGCCCCCGATATCGAAACGC
CGCTGGGCCTGCGGGACCGCACCATGCTCGAACTGATGTATGCGAGCGGGCTGCGCGTGTCCGAGCTCACGAACATGAAG
ACCATCGAAGTCGGCCTGAATGAAGGCGTGGCGCGCGTGGTTGGCGGCAAGGGCAACAAGGAGCGGCTGGTGCCATTCGG
CGCGCAGGCCGGCGACTGGCTGCATCGCTACCTGTCCGATGCGCGCCCCACGTTGCTGGCGGGCCGCGCGTGCGACGAAC
TCTTCGTCACGCAGCGCGGCGAGGGCATGACGCGCCAGACGTTCTGGCACCTGATCAAGAAACACGCGCGTGACGCGGGC
ATTCACGCCCCGCTCTCCCCGCATACGCTCCGGCACGCCTTTGCCACGCACCTGCTTAATCACGGCGCCGACCTGCGCGT
GGTGCAGCTGCTGCTGGGGCACGCCGATATCTCCACCACGCAGATCTACACGCACGTCGCGCGCGAGCGCCTGCGCGAAC
TGCACCTGCATCACCATCCGCGCGGCTGA

Upstream 100 bases:

>100_bases
TGGCGGCCAACGGACTCGGCGGCTTCGCGCATCATGGCGAGGAAGGATTCCATCTGGGCGTGAAGCGCTGGCTGCTGCGC
CATGAAGGCGCGATGCTGCT

Downstream 100 bases:

>100_bases
CCCGCGCGACCGACCACGCGATATGAGCAAGAGCAAGCACGTCTCCGAAACCCCCGCCACGCAAATGCTGCGCAAGCACG
GCGTCACGTTCGGCGAGCAC

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTAALDGDLSLVDRFCDALWLEDGLARNTIDAYRRDLAMLARWLHESGTTALLGVDDTALSGYFAARHLETRASSANRRL
TVFRRFYQWALREHMIEADPCLLLRPAKQPPRFPKTLSEAQVVALLEAPDIETPLGLRDRTMLELMYASGLRVSELTNMK
TIEVGLNEGVARVVGGKGNKERLVPFGAQAGDWLHRYLSDARPTLLAGRACDELFVTQRGEGMTRQTFWHLIKKHARDAG
IHAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRELHLHHHPRG

Sequences:

>Translated_302_residues
MTAALDGDLSLVDRFCDALWLEDGLARNTIDAYRRDLAMLARWLHESGTTALLGVDDTALSGYFAARHLETRASSANRRL
TVFRRFYQWALREHMIEADPCLLLRPAKQPPRFPKTLSEAQVVALLEAPDIETPLGLRDRTMLELMYASGLRVSELTNMK
TIEVGLNEGVARVVGGKGNKERLVPFGAQAGDWLHRYLSDARPTLLAGRACDELFVTQRGEGMTRQTFWHLIKKHARDAG
IHAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRELHLHHHPRG
>Mature_301_residues
TAALDGDLSLVDRFCDALWLEDGLARNTIDAYRRDLAMLARWLHESGTTALLGVDDTALSGYFAARHLETRASSANRRLT
VFRRFYQWALREHMIEADPCLLLRPAKQPPRFPKTLSEAQVVALLEAPDIETPLGLRDRTMLELMYASGLRVSELTNMKT
IEVGLNEGVARVVGGKGNKERLVPFGAQAGDWLHRYLSDARPTLLAGRACDELFVTQRGEGMTRQTFWHLIKKHARDAGI
HAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRELHLHHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=301, Percent_Identity=56.8106312292359, Blast_Score=318, Evalue=2e-88,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=34.9315068493151, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790768, Length=170, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=27.3255813953488, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33986; Mature: 33855

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAALDGDLSLVDRFCDALWLEDGLARNTIDAYRRDLAMLARWLHESGTTALLGVDDTAL
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
SGYFAARHLETRASSANRRLTVFRRFYQWALREHMIEADPCLLLRPAKQPPRFPKTLSEA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
QVVALLEAPDIETPLGLRDRTMLELMYASGLRVSELTNMKTIEVGLNEGVARVVGGKGNK
HEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCEEEEECCCCCHHHHHCCCCCC
ERLVPFGAQAGDWLHRYLSDARPTLLAGRACDELFVTQRGEGMTRQTFWHLIKKHARDAG
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
IHAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRELHLHHHP
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
RG
CC
>Mature Secondary Structure 
TAALDGDLSLVDRFCDALWLEDGLARNTIDAYRRDLAMLARWLHESGTTALLGVDDTAL
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
SGYFAARHLETRASSANRRLTVFRRFYQWALREHMIEADPCLLLRPAKQPPRFPKTLSEA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
QVVALLEAPDIETPLGLRDRTMLELMYASGLRVSELTNMKTIEVGLNEGVARVVGGKGNK
HEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCEEEEECCCCCHHHHHCCCCCC
ERLVPFGAQAGDWLHRYLSDARPTLLAGRACDELFVTQRGEGMTRQTFWHLIKKHARDAG
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
IHAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLRELHLHHHP
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
RG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]