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The map label for this gene is mdtA [H]

Identifier: 94309459

GI number: 94309459

Start: 550070

End: 551641

Strand: Reverse

Name: mdtA [H]

Synonym: Rmet_0514

Alternate gene names: 94309459

Gene position: 551641-550070 (Counterclockwise)

Preceding gene: 94309462

Following gene: 94309458

Centisome position: 14.04

GC content: 68.51

Gene sequence:

>1572_bases
ATGCTTCAGGCCATCCCCCTGACGGCGAGGCACCCTGCCCGTGCGATGCGGCATACTGCTGCAACTTCGACGTCACAATG
CTTGTGCGAATACCGTTGGCACGCCCCACTTTTTCGTCGTGCCGCTCCCAGGATTCCGGTCATGTCCAACCCAGAACAAG
GTCAACCCACTCCTCCCAATCCGCCCACACCGGGCGGTAATACCCGGTCGCGTCGCCGCACATGGATCGCCGGCGCAGTC
ATCGTCGTGCTAGCCGGTGCCGGCTGGTACTGGCACGGCCATCGCAAGGCCGCGCAGCAAGCCGGCGCCACGAGTGCCGG
CGCGGCCAGTGGCGCTGCCGGGATGGGCGCGGGCAAGCGGGGCCCCGGAGGCGCTAGCGGCGCCGGTGGCCCTGGCGGCC
CGGGCGCGCAGCAGCGCTCGCCAGTGGTGGTCAACCGCGTGACGCGCCGCAACATGGACGTGGTGCTGAACGGCCTGGGC
AACGTGACGCCGGTGGCCAACGTCACGGTGCGCGCGCAGGTCTCCGGCCCGCTGCTCAAAGTGCTGTTCAAGGAAGGCCA
GATGGTCAAGGCCGGCGACGTGCTCGCCGAAATCGACCCGCGCCCGTTCCAGGCCACGCTCGACCAGGCTGTCGGCCAAC
TCGCGCGCGACCAGGCATTGCTCCAGAACGCCCGCCTGGACCAGAAACGCTACAAGACGCTGCTGGCGCAGGACTCGATC
TCGAGCCAGCAGGTAGATACGCAGGACGCGCTGGTGCGCCAGTACGAGGGGACGGTCAAGACCGATCAGGGTAACGTCGA
CAACGCGCGCATCCAGCTTGGCTACACGCGCATCGTCGCGCCGACGTCGGGCCGCATTGGCCTGCGTCAGGTCGACCCGG
GCAATATCGTCAATCCAAGCGACACCAACGGCATCGCCCTGATCACCCAGATCCAGCCGATCGCGGTGCTGTACACGATC
CCCGAAGACAACCTGCCCTCGGTGCTGAAGAAGCTCAACGCCGGCGAGAAGCTGGCGGTGCAAGCCTGGGACCGCCAGAT
GCGCAACCAGCTCGGTGAAGGCACGCTGCTGACCACGGACAACCAGATCGACACCACCACGGGCACCGTCAAGCTCAAGG
CAATCTTCGCGAACACCGACGGCATGTTGTTCCCGAACCAGTTCGTCAACGTGCGCACGCGCATCGACACGCTGGAAGAC
GCCACCGTGATCCCGATCGCGGCGATCCAGCGGGGCCAGCAGGGCACGTTCGTGTATGTCGTGGATGACCAGAGCACGGT
CAAGGTGCAGGTCGTCACGCTCGGGCCGGGCGACGGTAGCCACAGCGCCGTGCTCAAGGGCCTGGAGCCCGGGCAGCGCG
TGGTTGTGGATGGCGCGGACCGCCTGAAGGAAGGCATGACCGTCGAGGCGGTAGACCCGGCGGCACGTGCCGCGGCGCTC
ACGCCGGCGAGTTCGCCACGCGCCCGCGGCCGTCGCGGCGGCGGCGCGAGCGGCGTCCACGGTGCCAGCGGCGCGCGGGC
AGCCAGCGGCGCCCATGGCTCGGGCGCGAGCCCGCAGCAGGCACAGCCGTAA

Upstream 100 bases:

>100_bases
CCCGGACCGTTTTGTTTCCGGAGGTTACACCCACGTCGTTGGTAATCCGCTGTAATAAAAGCAGGGCGCGGCGAAACAGG
TGGGATGGGAGCCGCACATT

Downstream 100 bases:

>100_bases
GGCGAGGAGTCGAGGAGCGGCATGAATCCCTCACGCATCTTTATCGAGCGGCCAGTCGCCACAGCGCTGCTGATGGTGGC
CATCCTGCTGTCGGGGCTGG

Product: multidrug efflux system, subunit A

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MLQAIPLTARHPARAMRHTAATSTSQCLCEYRWHAPLFRRAAPRIPVMSNPEQGQPTPPNPPTPGGNTRSRRRTWIAGAV
IVVLAGAGWYWHGHRKAAQQAGATSAGAASGAAGMGAGKRGPGGASGAGGPGGPGAQQRSPVVVNRVTRRNMDVVLNGLG
NVTPVANVTVRAQVSGPLLKVLFKEGQMVKAGDVLAEIDPRPFQATLDQAVGQLARDQALLQNARLDQKRYKTLLAQDSI
SSQQVDTQDALVRQYEGTVKTDQGNVDNARIQLGYTRIVAPTSGRIGLRQVDPGNIVNPSDTNGIALITQIQPIAVLYTI
PEDNLPSVLKKLNAGEKLAVQAWDRQMRNQLGEGTLLTTDNQIDTTTGTVKLKAIFANTDGMLFPNQFVNVRTRIDTLED
ATVIPIAAIQRGQQGTFVYVVDDQSTVKVQVVTLGPGDGSHSAVLKGLEPGQRVVVDGADRLKEGMTVEAVDPAARAAAL
TPASSPRARGRRGGGASGVHGASGARAASGAHGSGASPQQAQP

Sequences:

>Translated_523_residues
MLQAIPLTARHPARAMRHTAATSTSQCLCEYRWHAPLFRRAAPRIPVMSNPEQGQPTPPNPPTPGGNTRSRRRTWIAGAV
IVVLAGAGWYWHGHRKAAQQAGATSAGAASGAAGMGAGKRGPGGASGAGGPGGPGAQQRSPVVVNRVTRRNMDVVLNGLG
NVTPVANVTVRAQVSGPLLKVLFKEGQMVKAGDVLAEIDPRPFQATLDQAVGQLARDQALLQNARLDQKRYKTLLAQDSI
SSQQVDTQDALVRQYEGTVKTDQGNVDNARIQLGYTRIVAPTSGRIGLRQVDPGNIVNPSDTNGIALITQIQPIAVLYTI
PEDNLPSVLKKLNAGEKLAVQAWDRQMRNQLGEGTLLTTDNQIDTTTGTVKLKAIFANTDGMLFPNQFVNVRTRIDTLED
ATVIPIAAIQRGQQGTFVYVVDDQSTVKVQVVTLGPGDGSHSAVLKGLEPGQRVVVDGADRLKEGMTVEAVDPAARAAAL
TPASSPRARGRRGGGASGVHGASGARAASGAHGSGASPQQAQP
>Mature_523_residues
MLQAIPLTARHPARAMRHTAATSTSQCLCEYRWHAPLFRRAAPRIPVMSNPEQGQPTPPNPPTPGGNTRSRRRTWIAGAV
IVVLAGAGWYWHGHRKAAQQAGATSAGAASGAAGMGAGKRGPGGASGAGGPGGPGAQQRSPVVVNRVTRRNMDVVLNGLG
NVTPVANVTVRAQVSGPLLKVLFKEGQMVKAGDVLAEIDPRPFQATLDQAVGQLARDQALLQNARLDQKRYKTLLAQDSI
SSQQVDTQDALVRQYEGTVKTDQGNVDNARIQLGYTRIVAPTSGRIGLRQVDPGNIVNPSDTNGIALITQIQPIAVLYTI
PEDNLPSVLKKLNAGEKLAVQAWDRQMRNQLGEGTLLTTDNQIDTTTGTVKLKAIFANTDGMLFPNQFVNVRTRIDTLED
ATVIPIAAIQRGQQGTFVYVVDDQSTVKVQVVTLGPGDGSHSAVLKGLEPGQRVVVDGADRLKEGMTVEAVDPAARAAAL
TPASSPRARGRRGGGASGVHGASGARAASGAHGSGASPQQAQP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=409, Percent_Identity=43.7652811735941, Blast_Score=325, Evalue=4e-90,
Organism=Escherichia coli, GI1789665, Length=310, Percent_Identity=35.1612903225806, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786668, Length=310, Percent_Identity=34.8387096774194, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789929, Length=333, Percent_Identity=28.8288288288288, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI87081951, Length=119, Percent_Identity=36.1344537815126, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 54850; Mature: 54850

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQAIPLTARHPARAMRHTAATSTSQCLCEYRWHAPLFRRAAPRIPVMSNPEQGQPTPPN
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCC
PPTPGGNTRSRRRTWIAGAVIVVLAGAGWYWHGHRKAAQQAGATSAGAASGAAGMGAGKR
CCCCCCCCCHHHHHHHHHEEEEEEECCCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCC
GPGGASGAGGPGGPGAQQRSPVVVNRVTRRNMDVVLNGLGNVTPVANVTVRAQVSGPLLK
CCCCCCCCCCCCCCCCCCCCCCEEHHHHHCCHHHEEECCCCCCCCCEEEEEEECCCHHHH
VLFKEGQMVKAGDVLAEIDPRPFQATLDQAVGQLARDQALLQNARLDQKRYKTLLAQDSI
HHHHCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
SSQQVDTQDALVRQYEGTVKTDQGNVDNARIQLGYTRIVAPTSGRIGLRQVDPGNIVNPS
CCCCCCHHHHHHHHHCCCEECCCCCCCCEEEEEEEEEEEECCCCCCEEEECCCCCCCCCC
DTNGIALITQIQPIAVLYTIPEDNLPSVLKKLNAGEKLAVQAWDRQMRNQLGEGTLLTTD
CCCCEEEEEEECEEEEEEECCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCEEECC
NQIDTTTGTVKLKAIFANTDGMLFPNQFVNVRTRIDTLEDATVIPIAAIQRGQQGTFVYV
CCCCCCCCEEEEEEEEECCCCCCCCHHHEEEEHHHCCCCCCEEEEHHHHCCCCCCCEEEE
VDDQSTVKVQVVTLGPGDGSHSAVLKGLEPGQRVVVDGADRLKEGMTVEAVDPAARAAAL
ECCCCEEEEEEEEECCCCCCHHHHHCCCCCCCEEEEECHHHHHCCCEEEECCHHHHHEEC
TPASSPRARGRRGGGASGVHGASGARAASGAHGSGASPQQAQP
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLQAIPLTARHPARAMRHTAATSTSQCLCEYRWHAPLFRRAAPRIPVMSNPEQGQPTPPN
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCC
PPTPGGNTRSRRRTWIAGAVIVVLAGAGWYWHGHRKAAQQAGATSAGAASGAAGMGAGKR
CCCCCCCCCHHHHHHHHHEEEEEEECCCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCC
GPGGASGAGGPGGPGAQQRSPVVVNRVTRRNMDVVLNGLGNVTPVANVTVRAQVSGPLLK
CCCCCCCCCCCCCCCCCCCCCCEEHHHHHCCHHHEEECCCCCCCCCEEEEEEECCCHHHH
VLFKEGQMVKAGDVLAEIDPRPFQATLDQAVGQLARDQALLQNARLDQKRYKTLLAQDSI
HHHHCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
SSQQVDTQDALVRQYEGTVKTDQGNVDNARIQLGYTRIVAPTSGRIGLRQVDPGNIVNPS
CCCCCCHHHHHHHHHCCCEECCCCCCCCEEEEEEEEEEEECCCCCCEEEECCCCCCCCCC
DTNGIALITQIQPIAVLYTIPEDNLPSVLKKLNAGEKLAVQAWDRQMRNQLGEGTLLTTD
CCCCEEEEEEECEEEEEEECCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCEEECC
NQIDTTTGTVKLKAIFANTDGMLFPNQFVNVRTRIDTLEDATVIPIAAIQRGQQGTFVYV
CCCCCCCCEEEEEEEEECCCCCCCCHHHEEEEHHHCCCCCCEEEEHHHHCCCCCCCEEEE
VDDQSTVKVQVVTLGPGDGSHSAVLKGLEPGQRVVVDGADRLKEGMTVEAVDPAARAAAL
ECCCCEEEEEEEEECCCCCCHHHHHCCCCCCCEEEEECHHHHHCCCEEEECCHHHHHEEC
TPASSPRARGRRGGGASGVHGASGARAASGAHGSGASPQQAQP
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA