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The map label for this gene is yihE [H]

Identifier: 94309402

GI number: 94309402

Start: 485852

End: 486898

Strand: Direct

Name: yihE [H]

Synonym: Rmet_0457

Alternate gene names: 94309402

Gene position: 485852-486898 (Clockwise)

Preceding gene: 94309401

Following gene: 94309404

Centisome position: 12.37

GC content: 66.86

Gene sequence:

>1047_bases
ATGAGCGAGCCGGATCGTCCCTCGTCGACCGATGAAGTCCCCTACGCGGGACTGACCCCCGAGTGCATCCTCGATGCGCT
CGAGGCGGCGGGGTTCTATCCGGATGGGCGCTTGCTGGCGCTCAACAGCTACGAGAACCGCGTCTGGCAGGTGGGCATCG
AGGATGCCGCGCCGGTCGTCGCCAAGTTTTATCGGCCGGGCCGCTGGACCGATGCGGCGATCCTTGAGGAACATGCATTC
GTGCAGCAGCTGGCCGGTGCGGAAGTGCCTGCTGTGCCGGCCCTGGCGGCCAATAGCGGCGACCAGTCCGGCACCACGCT
GTTCACACACGAGGGCTTCCGCTTCGCGGTGTTTCCACGTTGCGGGGGCCGCGAACCCGCGCTCGACAAGGCCGAAACCC
GCACCTGGCTCGGGCGCTTCATCGGCCGTATTCACGCCATCGGCGCCACCGCGCCATACCAGGCGCGGCCCGCGCTGGAT
ATCGATACTTTCGGCATTGCATCGCGCGACTATCTGCTCGCGCACGATTGCATTCCCGCCGACCTGCTGGCGCCCTGGCG
TGCGGCGGCGGACCTCGCGCTGGACGGTGTGCGCCGCAGCTACGAGCGTGCCGGAGAGGTTCGCCTGTTGCGTCTGCATG
GGGATTGCCATCGCGGCAATGTGTTGTGGATCGACGAAGAGGATGCACGCGGCCGGGGCACACCCGGGCCGCACTTCGTT
GATTTCGATGACAGCCGCATGGGACCGGCCGTGCAGGATCTGTGGATGCTGCTGGAGGGAGACCGCGTGGCGATGCAGGA
CCAGTTGGCCGACATCGTGGCGGGTTACGAGGACTTCGCGGAATTCGATGCGAGGGAGCTCTGGCTGGTCGAGGCACTTC
GCACGCTGCGCCTGTTGCACTACAGCGCGTGGCTGGCCAGCCGATGGCGCGATCCCGCCTTTCCGGCCGCGTTTCCGTGG
TTCGGCACGGCGCGTTACTGGCAGGATCGCATTCTGGAGTTGCGCGAACAGATCGCGCTCATGGACGAGGCGCCGCTCTG
GGCCTGA

Upstream 100 bases:

>100_bases
AGGACAACACTGCCGCGCCGCCCGCTCGCAATCGTCGGCCGGCCCCGCAGGCGGCCCTGCTCGGCGGTGGCCGCAAGCCC
GCCCACTGATCGCATCCGTC

Downstream 100 bases:

>100_bases
CATCAGCCCGAAGCCGCGCCGTCATGGAACAGCTTGGCCCGAACGGGCCGGCCTTCAGCTTTTTTCCGGCTTGACCATGA
TTACCGGGCATCCGGCGTGC

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSEPDRPSSTDEVPYAGLTPECILDALEAAGFYPDGRLLALNSYENRVWQVGIEDAAPVVAKFYRPGRWTDAAILEEHAF
VQQLAGAEVPAVPALAANSGDQSGTTLFTHEGFRFAVFPRCGGREPALDKAETRTWLGRFIGRIHAIGATAPYQARPALD
IDTFGIASRDYLLAHDCIPADLLAPWRAAADLALDGVRRSYERAGEVRLLRLHGDCHRGNVLWIDEEDARGRGTPGPHFV
DFDDSRMGPAVQDLWMLLEGDRVAMQDQLADIVAGYEDFAEFDARELWLVEALRTLRLLHYSAWLASRWRDPAFPAAFPW
FGTARYWQDRILELREQIALMDEAPLWA

Sequences:

>Translated_348_residues
MSEPDRPSSTDEVPYAGLTPECILDALEAAGFYPDGRLLALNSYENRVWQVGIEDAAPVVAKFYRPGRWTDAAILEEHAF
VQQLAGAEVPAVPALAANSGDQSGTTLFTHEGFRFAVFPRCGGREPALDKAETRTWLGRFIGRIHAIGATAPYQARPALD
IDTFGIASRDYLLAHDCIPADLLAPWRAAADLALDGVRRSYERAGEVRLLRLHGDCHRGNVLWIDEEDARGRGTPGPHFV
DFDDSRMGPAVQDLWMLLEGDRVAMQDQLADIVAGYEDFAEFDARELWLVEALRTLRLLHYSAWLASRWRDPAFPAAFPW
FGTARYWQDRILELREQIALMDEAPLWA
>Mature_347_residues
SEPDRPSSTDEVPYAGLTPECILDALEAAGFYPDGRLLALNSYENRVWQVGIEDAAPVVAKFYRPGRWTDAAILEEHAFV
QQLAGAEVPAVPALAANSGDQSGTTLFTHEGFRFAVFPRCGGREPALDKAETRTWLGRFIGRIHAIGATAPYQARPALDI
DTFGIASRDYLLAHDCIPADLLAPWRAAADLALDGVRRSYERAGEVRLLRLHGDCHRGNVLWIDEEDARGRGTPGPHFVD
FDDSRMGPAVQDLWMLLEGDRVAMQDQLADIVAGYEDFAEFDARELWLVEALRTLRLLHYSAWLASRWRDPAFPAAFPWF
GTARYWQDRILELREQIALMDEAPLWA

Specific function: Probably involved in the extracytoplasmic stress response [H]

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rdoA family [H]

Homologues:

Organism=Escherichia coli, GI1790290, Length=332, Percent_Identity=43.6746987951807, Blast_Score=267, Evalue=6e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: NA

Molecular weight: Translated: 38922; Mature: 38791

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPDRPSSTDEVPYAGLTPECILDALEAAGFYPDGRLLALNSYENRVWQVGIEDAAPVV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCHHHHHH
AKFYRPGRWTDAAILEEHAFVQQLAGAEVPAVPALAANSGDQSGTTLFTHEGFRFAVFPR
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEECCEEEEEECC
CGGREPALDKAETRTWLGRFIGRIHAIGATAPYQARPALDIDTFGIASRDYLLAHDCIPA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCH
DLLAPWRAAADLALDGVRRSYERAGEVRLLRLHGDCHRGNVLWIDEEDARGRGTPGPHFV
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCEEE
DFDDSRMGPAVQDLWMLLEGDRVAMQDQLADIVAGYEDFAEFDARELWLVEALRTLRLLH
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHH
YSAWLASRWRDPAFPAAFPWFGTARYWQDRILELREQIALMDEAPLWA
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEPDRPSSTDEVPYAGLTPECILDALEAAGFYPDGRLLALNSYENRVWQVGIEDAAPVV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCHHHHHH
AKFYRPGRWTDAAILEEHAFVQQLAGAEVPAVPALAANSGDQSGTTLFTHEGFRFAVFPR
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEECCEEEEEECC
CGGREPALDKAETRTWLGRFIGRIHAIGATAPYQARPALDIDTFGIASRDYLLAHDCIPA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCH
DLLAPWRAAADLALDGVRRSYERAGEVRLLRLHGDCHRGNVLWIDEEDARGRGTPGPHFV
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCEEE
DFDDSRMGPAVQDLWMLLEGDRVAMQDQLADIVAGYEDFAEFDARELWLVEALRTLRLLH
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHH
YSAWLASRWRDPAFPAAFPWFGTARYWQDRILELREQIALMDEAPLWA
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]